José Brás - Publications, H-index & Citations

José Brás

van andel institute

84H指数

382论文数

4.4W被引数

收录论文 128

发表时间

Maternal Longevity is Associated With Reduced Risk but an Earlier Onset of Alzheimer’s Disease in Offspring 母体长寿与后代患阿尔茨海默病风险降低但发病年龄提前相关

Journal of Geriatric Psychiatry and Neurology

IF2.5

2026-02-16

PREAI

Miguel Tábuas-Pereira; Francisco Mano; Catarina Bernardes; João Durães; Marisa Lima; Kaitlyn DenHaan; Kimberly Paquette; Célia Kun-Rodrigues; Susana Carmona; Teresa Tábuas; Pedro Faustino; Mariana Ruth Coelho; Anuschka Silva-Spínola; Diana Duro; Maria Rosário Almeida; João Malva; Inês Baldeiras; José Brás; Rita Guerreiro; Isabel Santana

Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer’s disease 疾病突变的结构域定位揭示了阿尔茨海默氏病的致病性SORL1变体

Molecular Neurodegeneration

IF17.5

2025-12-01

OAAI

Olav M. Andersen; Matthijs W. J. de Waal; Giulia Monti; Niccolo Tesi; Anne Mette G. Jensen; Christa de Geus; Rosalina van Spaendonk; Maartje Vogel; Shahzad Ahmad; Najaf Amin; Philippe Amouyel; Gary W. Beecham; Céline Bellenguez; Claudine Berr; Joshua C. Bis; Anne Boland; Paola Bossù; Femke Bouwman; Jose Bras; Camille Charbonnier; Jordi Clarimon; Carlos Cruchaga; Antonio Daniele; Jean-François Dartigues; Stéphanie Debette; Jean-François Deleuze; Nicola Denning; Anita L. DeStefano; Oriol Dols-Icardo; Cornelia M. van Duijn; Lindsay A. Farrer; Maria Victoria Fernández; Wiesje M. van der Flier; Nick C. Fox; Daniela Galimberti; Emmanuelle Genin; Johan J. P. Gille; Benjamin Grenier-Boley; Detelina Grozeva; Yann Le Guen; Rita Guerreiro; Jonathan L. Haines; Clive Holmes; Holger Hummerich; M. Arfan Ikram; M. Kamran Ikram; Amit Kawalia; Robert Kraaij; Jean-Charles Lambert; Marc Lathrop; Afina W. Lemstra; Alberto Lleó; Richard M. Myers; Marcel M. A. M. Mannens; Rachel Marshall; Eden R. Martin; Carlo Masullo; Richard Mayeux; Simon Mead; Patrizia Mecocci; Alun Meggy; Merel O. Mol; Benedetta Nacmias; Adam C. Naj; Valerio Napolioni; J. Nicholas Cochran; Gaël Nicolas; Florence Pasquier; Pau Pastor; Margaret A. Pericak-Vance; Yolande A. L. Pijnenburg; Fabrizio Piras; Olivier Quenez; Alfredo Ramirez; Rachel Raybould; Richard Redon; Marcel J. T. Reinders; Anne-Claire Richard; Steffi G. Riedel-Heller; Fernando Rivadeneira; Jeroen G. J. van Rooij; Stéphane Rousseau; Natalie S. Ryan; Pascual Sanchez-Juan; Gerard D. Schellenberg; Philip Scheltens; Jonathan M. Schott; Sudha Seshadri; Daoud Sie; Rebecca Sims; Erik A. Sistermans; Sandro Sorbi; John C. van Swieten; Betty Tijms; André G. Uitterlinden; Pieter Jelle Visser; Michael Wagner; David Wallon; Li-San Wang; Julie Williams; Jennifer S. Yokoyama; Aline Zarea; Sven J. van der Lee; Johan G. Olsen; Marc Hulsman; Henne Holstege

Genome-wide association study of neuropathological features in Lewy body disease Lewy体病神经病理学特征的全基因组关联研究

BRAIN

IF11.7

2025-06-01

PREAI

Valentino, Rebecca R.; Koga, Shunsuke; Soto-Beasley, Alexandra, I; Ono, Daisuke; Wieczorek, Mikolaj A.; Johnson, Patrick W.; White, Launia J.; Watkins, Molly M.; Murray, Melissa E.; Kasanuki, Koji; McLean, Pamela J.; Springer, Wolfdieter; Uitti, Ryan J.; Fields, Julie A.; Botha, Hugo; Ramanan, Vijay K.; Kantarci, Kejal; Lowe, Val J.; Jack Jr, Clifford R.; Bras, Jose; Guerreiro, Rita; Ertekin-Taner, Nilufer; Savica, Rodolfo; Graff-Radford, Jonathan; Petersen, Ronald C.; Parisi, Joseph E.; Reichard, R. Ross; Graff-Radford, Neill R.; Ferman, Tanis J.; Boeve, Bradley F.; Wszolek, Zbigniew K.; Dickson, Dennis W.; Heckman, Michael G.; Ross, Owen A.

Genome-wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease 全基因组关联分析确定APOE是路易体病中线粒体自噬的修饰因子

ALZHEIMERS & DEMENTIA

IF11.1

2025-05-01

OAAI

Hou, X; Heckman, MG; Fiesel, FC; Koga, S; Soto-Beasley, AI; Watzlawik, JO; Zhao, J; Valentino, RR; Johnson, PW; White, LJ; Quicksall, ZS; Reddy, JS; Bras, J; Guerreiro, R; Zhao, N; Bu, GJ; Dickson, DW; Ross, OA; Springer, W

Exome sequencing of a Portuguese cohort of early-onset Alzheimer's disease implicates the X-linked lysosomal gene GLA

SCIENTIFIC REPORTS

IF3.9

2025-04-04

OAAI

Tabuas-Pereira, Miguel; Bras, Jose; Taipa, Ricardo; Del Tredici, Kelly; Paquette, Kimberly; Chaudhry, Sophia; Denhaan, Kaitlyn; Duraes, Joao; Lima, Marisa; Bernardes, Catarina; Carmona, Susana; Baldeiras, Ines; Almeida, Rosario; Santana, Isabel; Guerreiro, Rita

Lysosomal polygenic risk is associated with the severity of neuropathology in Lewy body disease

BRAIN

IF11.7

2023-05-29

OAAI

Tunold, Jon-Anders; Tan, Manuela M. X.; Koga, Shunsuke; Geut, Hanneke; Rozemuller, Annemieke J. M.; Valentino, Rebecca; Sekiya, Hiroaki; Martin, Nicholas B.; Heckman, Michael G.; Bras, Jose; Guerreiro, Rita; Dickson, Dennis W.; Toft, Mathias; van de Berg, Wilma D. J.; Ross, Owen A.; Pihlstrom, Lasse

Reply to: Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates

SCIENTIFIC REPORTS

IF3.9

2023-03-14

OAAI

Guerreiro, Rita; Bras, Jose

TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients

NEUROBIOLOGY OF AGING

IF3.5

2023-03-01

OAAI

Foddis, Marco; Blumenau, Sonja; Holtgrewe, Manuel; Paquette, Kimberly; Westra, Kaitlyn; Alonso, Isabel; Macario, Maria do Carmo; Morgadinho, Ana Sofia; Velon, Ana Graca; Santo, Gustavo; Santana, Isabel; Monkare, Saana; Kuuluvainen, Liina; Schleutker, Johanna; Poyhonen, Minna; Myllykangas, Liisa; Pavlovic, Aleksandra; Kostic, Vladimir; Dobricic, Valerija; Lohmann, Ebba; Hanagasi, Hasmet; Santos, Mariana; Guven, Gamze; Bilgic, Basar; Bras, Jose; Beule, Dieter; Dirnagl, Ulrich; Guerreiro, Rita; Sassi, Celeste

Reconsidering the role of blood-brain barrier in Alzheimer's disease: From delivery to target 重新考虑血脑屏障在阿尔茨海默病中的作用: 从交付到目标

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2023-02-16

OAAI

Sousa, Joao Andre; Bernardes, Catarina; Bernardo-Castro, Sara; Lino, Miguel; Albino, Ines; Ferreira, Lino; Bras, Jose; Guerreiro, Rita; Tabuas-Pereira, Miguel; Baldeiras, Ines; Santana, Isabel; Sargento-Freitas, Joao

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease 外显子组测序鉴定ATP8B4和ABCA1中罕见的破坏性变异为阿尔茨海默病的危险因素

NATURE GENETICS

IF31.8

2022-11-21

OAAI

Holstege, Henne; Hulsman, Marc; Charbonnier, Camille; Grenier-Boley, Benjamin; Quenez, Olivier; Grozeva, Detelina; van Rooij, Jeroen G. J.; Sims, Rebecca; Ahmad, Shahzad; Amin, Najaf; Norsworthy, Penny J.; Dols-Icardo, Oriol; Hummerich, Holger; Kawalia, Amit; Amouyel, Philippe; Beecham, Gary W.; Berr, Claudine; Bis, Joshua C.; Boland, Anne; Bossu, Paola; Bouwman, Femke; Bras, Jose; Campion, Dominique; Cochran, J. Nicholas; Daniele, Antonio; Dartigues, Jean-Francois; Debette, Stephanie; Deleuze, Jean-Francois; Denning, Nicola; DeStefano, Anita L.; Farrer, Lindsay A.; Fernandez, Maria Victoria; Fox, Nick C.; Galimberti, Daniela; Genin, Emmanuelle; Gille, Johan J. P.; Le Guen, Yann; Guerreiro, Rita; Haines, Jonathan L.; Holmes, Clive; Ikram, M. Arfan; Ikram, M. Kamran; Jansen, Iris E.; Kraaij, Robert; Lathrop, Marc; Lemstra, Afina W.; Lleo, Alberto; Luckcuck, Lauren; Mannens, Marcel M. A. M.; Marshall, Rachel; Martin, Eden R.; Masullo, Carlo; Mayeux, Richard; Mecocci, Patrizia; Meggy, Alun; Mol, Merel O.; Morgan, Kevin; Myers, Richard M.; Nacmias, Benedetta; Naj, Adam C.; Napolioni, Valerio; Pasquier, Florence; Pastor, Pau; Pericak-Vance, Margaret A.; Raybould, Rachel; Redon, Richard; Reinders, Marcel J. T.; Richard, Anne-Claire; Riedel-Heller, Steffi G.; Rivadeneira, Fernando; Rousseau, Stephane; Ryan, Natalie S.; Saad, Salha; Sanchez-Juan, Pascual; Schellenberg, Gerard D.; Scheltens, Philip; Schott, Jonathan M.; Seripa, Davide; Seshadri, Sudha; Sie, Daoud; Sistermans, Erik A.; Sorbi, Sandro; van Spaendonk, Resie; Spalletta, Gianfranco; Tesi, Niccolo'; Tijms, Betty; Uitterlinden, Andre G.; van der Lee, Sven J.; Visser, Pieter Jelle; Wagner, Michael; Wallon, David; Wang, Li-San; Zarea, Aline; Clarimon, Jordi; van Swieten, John C.; Greicius, Michael D.; Yokoyama, Jennifer S.; Cruchaga, Carlos; Hardy, John; Ramirez, Alfredo; Mead, Simon; van der Flier, Wiesje M.; van Duijn, Cornelia M.; Williams, Julie; Nicolas, Gael; Bellenguez, Celine; Lambert, Jean-Charles

Challenge accepted: Uncovering the role of rare genetic variants in Alzheimer's disease (vol 17, 3, 2021)

MOLECULAR NEURODEGENERATION

IF17.5

2022-11-01

OAAI

Khani, Marzieh; Gibbons, Elizabeth; Bras, Jose; Guerreiro, Rita

MED27, SLC6A7, and MPPE1 Variants in a Complex Neurodevelopmental Disorder with Severe Dystonia

MOVEMENT DISORDERS

IF7.6

2022-07-25

OAAI

Reid, Kimberley M.; Spaull, Robert; Salian, Smrithi; Barwick, Katy; Meyer, Esther; Zhen, Juan; Hirata, Hiromi; Sheipouri, Diba; Benkerroum, Hind; Gorman, Kathleen M.; Papandreou, Apostolos; Simpson, Michael A.; Hirano, Yoshinobu; Farabella, Irene; Topf, Maya; Grozeva, Detelina; Carss, Keren; Smith, Martin; Pall, Hardev; Lunt, Peter; De Gressi, Susanna; Kamsteeg, Erik-Jan; Haack, Tobias B.; Carr, Lucinda; Guerreiro, Rita; Bras, Jose; Maher, Eamonn R.; Scott, Richard H.; Vandenberg, Robert J.; Raymond, F. Lucy; Chong, Wui K.; Sudhakar, Sniya; Mankad, Kshitij; Reith, Maarten E.; Campeau, Philippe M.; Harvey, Robert J.; Kurian, Manju A.

Genome-wide association of polygenic risk extremes for Alzheimer's disease in the UK Biobank

SCIENTIFIC REPORTS

IF3.9

2022-05-19

OAAI

Gouveia, Catarina; Gibbons, Elizabeth; Dehghani, Nadia; Eapen, James; Guerreiro, Rita; Bras, Jose

Molecular Characterization of Portuguese Patients with Hereditary Cerebellar Ataxia 葡萄牙遗传性小脑共济失调患者的分子特征

CELLS

IF5.2

2022-03-12

OAAI

Santos, Mariana; Damasio, Joana; Carmona, Susana; Neto, Joao Luis; Dehghani, Nadia; Guedes, Leonor Correia; Barbot, Clara; Barros, Jose; Bras, Jose; Sequeiros, Jorge; Guerreiro, Rita

In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-01-26

OAAI

Killinger, Bryan A.; Marshall, Lee L.; Chatterjee, Diptaman; Chu, Yaping; Bras, Jose; Guerreiro, Rita; Kordower, Jeffrey H.

Challenge accepted: uncovering the role of rare genetic variants in Alzheimer's disease

MOLECULAR NEURODEGENERATION

IF17.5

2022-01-09

OAAI

Khani, Marzieh; Gibbons, Elizabeth; Bras, Jose; Guerreiro, Rita

Prion-like α-synuclein pathology in the brain of infants with Krabbe disease

BRAIN

IF11.7

2022-01-06

OAAI

Hatton, Christopher; Ghanem, Simona S.; Koss, David J.; Abdi, Ilham Y.; Gibbons, Elizabeth; Guerreiro, Rita; Bras, Jose; Walker, Lauren; Gelpi, Ellen; Heywood, Wendy; Outeiro, Tiago F.; Attems, Johannes; McFarland, Robert; Forsyth, Rob; El-Agnaf, Omar M.; Erskine, Daniel

A comprehensive analysis of copy number variation in a Turkish dementia cohort

HUMAN GENOMICS

IF4.3

2021-07-28

OAAI

Dehghani, Nadia; Guven, Gamze; Kun-Rodrigues, Celia; Gouveia, Catarina; Foster, Kalina; Hanagasi, Hasmet; Lohmann, Ebba; Samanci, Bedia; Gurvit, Hakan; Bilgic, Basar; Bras, Jose; Guerreiro, Rita

How understudied populations have contributed to our understanding of Alzheimer's disease genetics (vol 144, pg 1067, 2021)

BRAIN

IF11.7

2021-05-20

OAAI

Dehghani, Nadia; Bras, Jose; Guerreiro, Rita

Genetic variants in glutamate-, Aβ-, and tau-related pathways determine polygenic risk for Alzheimer's disease

NEUROBIOLOGY OF AGING

IF3.5

2021-05-01

OAAI

Lawingco, Ted; Chaudhury, Sultan; Brookes, Keeley J.; Guetta-Baranes, Tamar; Guerreiro, Rita; Bras, Jose; Hardy, John; Francis, Paul; Thomas, Alan; Belbin, Olivia; Morgan, Kevin

研究方向