Wolfgang Hoyer

Forschungszentrum Julich

H指数:35

被引数:7,205

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Liquid-liquid phase-separated tau colocalizes with and stabilizes Aβ oligomers

液-液相分离的tau蛋白与Aβ寡聚物共定位并稳定其结构

Communications Chemistry

IF6.2

2026-08-100

An islet amyloid polypeptide oligomer model inhibits fibril formation

胰岛淀粉样多肽寡聚物模型抑制原纤维形成

Biophysical Chemistry

IF2.2

2026-04-290

OAAI

Peptidomimetics Inspired by α-Synuclein or Its Chaperone αB-Crystallin Differentially Modulate α-Synuclein Aggregation

Journal of Medicinal Chemistry

IF6.8

2026-01-230

PRE

Direct disassembly of α-syn preformed fibrils into α-syn monomers by an all-D-peptide

通过一种全D-肽将α-syn预形成原纤维直接解离为α-syn单体

npj Parkinson's Disease

IF0

2025-09-220

OAAI

Off-pathway oligomers of x-synuclein and A/β inhibit secondary nucleation of x-synuclein amyloid fibrils

X-突触蛋白和A/β的非通路寡聚体抑制X-突触蛋白淀粉样纤维的次级成核

JOURNAL OF MOLECULAR BIOLOGY

IF4.5

2025-02-010

OAAI

Disordered regions of inhibitor-bound α- synuclein suppress seed-induced fibril nucleation in cells

CELL REPORTS PHYSICAL SCIENCE

IF7.3

2024-09-010

Phase Separation and Aggregation of α-Synuclein Diverge at Different Salt Conditions

不同盐条件下 α-突触核蛋白的相分离和聚集

ADVANCED SCIENCE

IF14.1

2024-07-070

Editorial: The biochemistry of amyloids in neurodegenerative diseases, volume II

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-06-270

OAAI

Development and Implementation of an Internal Quality Control Sample to Standardize Oligomer-Based Diagnostics of Alzheimer's Disease

DIAGNOSTICS

IF3.3

2023-05-114

OAAI

Amyloid oligomers as on-pathway precursors or off-pathway competitors of fibrils

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2023-02-0922

OAAI

The role of heat shock proteins in preventing amyloid toxicity

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2022-12-151

OAAI

Cucurbit[7]uril Inhibits Islet Amyloid Polypeptide Aggregation by Targeting N Terminus Hot Segments and Attenuates Cytotoxicity

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2022-06-142

OAAI

Cucurbit[7]uril Inhibits Islet Amyloid Polypeptide Aggregation by Targeting N Terminus Hot Segments and Attenuates Cytotoxicity

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2022-05-316

PRE

Structural basis for the inhibition of IAPP fibril formation by the co-chaperonin prefoldin

NATURE COMMUNICATIONS

IF15.7

2022-05-025

OAAI

Alpha-Synuclein-Specific Naturally Occurring Antibodies Inhibit Aggregation In Vitro and In Vivo

BIOMOLECULES

IF4.8

2022-03-1810

OAAI

Editorial: The Biochemistry of Amyloids in Neurodegenerative Diseases, Volume I

FRONTIERS IN NEUROSCIENCE

IF3.2

2021-12-160

OAAI

Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting

内溶酶体a β 浓度和pH触发a β 寡聚体的形成，从而有效诱导Tau错误分选

NATURE COMMUNICATIONS

IF15.7

2021-07-3059

OAAI

A β-Wrapin Targeting the N-Terminus of α-Synuclein Monomers Reduces Fibril-Induced Aggregation in Neurons

FRONTIERS IN NEUROSCIENCE

IF3.2

2021-07-1310

OAAI

β-Turn exchanges in the α-synuclein segment 44-TKEG-47 reveal high sequence fidelity requirements of amyloid fibril elongation

Α-突触核蛋白片段44-TKEG-47中的 β 转角交换揭示了淀粉样蛋白原纤维延伸的高序列保真度要求

BIOPHYSICAL CHEMISTRY

IF2.2

2021-02-0114

OAAI

Structural details of amyloid β oligomers in complex with human prion protein as revealed by solid-state MAS NMR spectroscopy

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-0124

OAAI

Wolfgang Hoyer

个人简介

教育背景

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