Sushma Singh - Publications, H-index & Citations

Sushma Singh

jawaharlal nehru university, new delhi

24H指数

90论文数

1.5K被引数

收录论文 22

发表时间

Immunization with glutamine synthetase-deficient live attenuated parasites induces the differentiation of memory T cells to protect hosts from virulent infection of Leishmania donovani 用缺乏谷氨酰胺合酶的活减毒寄生虫进行免疫，可诱导记忆T细胞的分化，以保护宿主免受利什曼原虫（Leishmania donovani）的毒力感染。

Vaccine

IF3.5

2025-07-15

PREAI

Sanhita Ghosh; Kamalika Roy; Vinay Kumar; Mintu Karan; Sharmistha Paul; Debolina Manna; Monalisa Ray; Mousumi Das; Budhaditya Mukherjee; Sushma Singh; Chiranjib Pal

Repurposing of propafenone, an FDA approved anti-arrhythmic drug for antileishmanial therapy 普罗帕酮的再利用，一种FDA批准的抗心律失常药物用于抗利什曼治疗

Biochimie

IF3

2025-06-21

PREAI

Anindita Paul; Pradyot Kumar Roy; Sandra Lalchhuanawmi; Neerupudi Kishore Babu; Mohd Faiz Khan; Sushma Singh

Mechanistic and structural insights into vitamin B2 metabolizing enzyme riboflavin kinase from Leishmania donovani 多诺瓦尼利什曼原虫维生素B2代谢酶核黄素激酶的机理和结构见解

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-10-01

PREAI

Roy, Pradyot Kumar; Paul, Anindita; Khandibharad, Shweta; Kolhe, Sanket Dattatray; Farooque, Qureshi Sameer Shaikh; Singh, Shailza; Singh, Sushma

Pyridoxal kinase gene deletion leads to impaired growth, deranged redox metabolism and cell cycle arrest in Leishmania donovani

BIOCHIMIE

IF3

2024-07-01

PREAI

Roy, Pradyot Kumar; Paul, Anindita; Lalchhuanawmi, Sandra; Babu, Neerupudi Kishore; Singh, Sushma

Analytical method development, validation, and out-of-specification investigations for polyethylene glycol

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2023-10-01

PREAI

Huang, Tyler C.; Chu, Gaosheng; Singh, Sushma

Leishmania donovani 6-phosphogluconolactonase: Crucial for growth and host infection?

MICROBIAL PATHOGENESIS

IF3.5

2023-05-01

PREAI

Paul, Anindita; Roy, Pradyot Kumar; Babu, Neerupudi Kishore; Dhumal, Tushar Tukaram; Singh, Sushma

Molecular explorations of the Leishmania donovani 6-phosphogluconolactonase enzyme, a key player in the pentose phosphate pathway

BIOCHIMIE

IF3

2022-11-01

PREAI

Dhumal, Tushar Tukaram; Kumar, Rajender; Paul, Anindita; Roy, Pradyot Kumar; Garg, Prabha; Singh, Sushma

A Core-Linker-Polyamine (CLP) Strategy Enables Rapid Discovery of Antileishmanial Aminoalkylquinolinecarboxamides That Target Oxidative Stress Mechanism

CHEMMEDCHEM

IF3.4

2022-07-08

PREAI

Shah, Archana P.; Hura, Neha; Babu, Neerupudi Kishore; Roy, Nibedita; Rao, Vajja Krishna; Paul, Anindita; Roy, Pradyot Kumar; Singh, Sushma; Guchhait, Sankar K.

Identification of 2-arylquinazolines with alkyl-polyamine motifs as potent antileishmanial agents: synthesis and biological evaluation studies

RSC MEDICINAL CHEMISTRY

IF3.6

2022-01-01

OAAI

Kumari, Anjila; Jaiswal, Tara; Kumar, Vinay; Hura, Neha; Kumar, Gulshan; Babu, Neerupudi Kishore; Acharya, Ayan; Roy, Pradyot K.; Guchhait, Sankar K.; Singh, Sushma

Targeting the Trypanothione Reductase of Tissue-Residing Leishmania in Hosts' Reticuloendothelial System: A Flexible Water-Soluble Ferrocenylquinoline-Based Preclinical Drug Candidate 靶向宿主网状内皮系统中组织存在的利什曼原虫的锥虫硫酮还原酶: 一种灵活的水溶性二茂铁基喹啉基临床前候选药物

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-12-09

PREAI

Mukherjee, Debarati; Yousuf, Md; Dey, Somaditya; Chakraborty, Sondipon; Chaudhuri, Ankur; Kumar, Vinay; Sarkar, Biswajyoti; Nath, Supriya; Hussain, Aabid; Dutta, Aritri; Mishra, Tanushree; Roy, Biswajit Gopal; Singh, Sushma; Chakraborty, Sibani; Adhikari, Susanta; Pal, Chiranjib

Structural exploration of glutamine synthetase from Leishmania donovani: Insights from in silico and in vitro analysis

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2020-03-01

PREAI

Kumar, Vinay; Sri, N. Sushma; Tripathi, Neha; Sharma, Vishnu K.; Bharatam, Prasad V.; Garg, Prabha; Singh, Sushma

Pyridoxal kinase: A vitamin B6 salvage pathway enzyme from Leishmania donovani 吡哆醛激酶: 一种来自多氏利什曼原虫的维生素B6补救途径酶

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2018-11-01

PREAI

Kumar, Vinay; Sharma, Mahesh; Rakesh, Bhadoriya Ruchita; Malik, Chandan Kumar; Neelagiri, Soumya; Neerupudi, Kishore Babu; Garg, Prabha; Singh, Sushma

Biochemical and inhibition studies of glutamine synthetase from Leishmania donovani

MICROBIAL PATHOGENESIS

IF3.5

2017-06-01

PREAI

Kumar, Vinay; Yadav, Shailendra; Soumya, Neelagiri; Kumar, Rohit; Babu, Neerupudi Kishore; Singh, Sushma

AMP-acetyl CoA synthetase from Leishmania donovani: Identification and functional analysis of 'PX4GK' motif

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2015-04-01

PREAI

Soumya, Neelagiri; Kumar, I. Sravan; Shivaprasad, S.; Gorakh, Landage Nitin; Dinesh, Neeradi; Swamy, Kayala Kambagiri; Singh, Sushma

Leishmania donovani eukaryotic initiation factor 5A: Molecular characterization, localization and homology modelling studies

MICROBIAL PATHOGENESIS

IF3.5

2014-08-01

PREAI

Singh, Sushma; Raju, K.; Jatekar, Deepika; Dinesh, Neeradi; Paul, M. Stanley; Sobhia, M. E.

Chemical- and Thermal-Induced Unfolding of Leishmania donovani Ribose-5-Phosphate Isomerase B: a Single-Tryptophan Protein

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

IF3.3

2014-06-07

PREAI

Kaur, Preet Kamal; Supin, Jakka S.; Rashmi, S.; Singh, Sushma

Exploring Leishmania donovani 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) as a potential drug target by biochemical, biophysical and inhibition studies

MICROBIAL PATHOGENESIS

IF3.5

2014-01-01

PREAI

Dinesh, Neeradi; Pallerla, Dheeraj Sree Ram; Kaur, Preet Kamal; Babu, Neerupudi Kishore; Singh, Sushma

Identification and Characterization of a Novel Deoxyhypusine Synthase in Leishmania donovani

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-01-01

OAAI

Chawla, Bhavna; Jhingran, Anupam; Singh, Sushma; Tyagi, Nidhi; Park, Myung Hee; Srinivasan, N.; Roberts, Sigrid C.; Madhubala, Rentala

Characterization of the Entamoeba histolytica Ornithine Decarboxylase-Like Enzyme

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2008-01-02

OAAI

Jhingran, Anupam; Padmanabhan, Prasad K.; Singh, Sushma; Anamika, Krishanpal; Bakre, Abhijeet A.; Bhattacharya, Sudha; Bhattacharya, Alok; Srinivasan, Narayanaswamy; Madhubala, Rentala

Antileishmanial effect of 3-aminooxy-1-aminopropane is due to polyamine depletion

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2007-02-01

OAAI

Singh, Sushma; Mukherjee, Angana; Khomutov, Alex R.; Persson, Lo; Heby, Olle; Chatterjee, Mitali; Madhubala, Rentala

研究方向