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Nicholas J. Paradis

Rowan University

H指数:7

被引数:167

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Elucidating HER2-directed chimeric antigen receptor (CAR) activation mechanism using homology modeling and all-atom molecular dynamics simulation.

利用同源建模和全原子分子动力学模拟阐明HER2靶向嵌合抗原受体(CAR)的激活机制。

Computational and Structural Biotechnology Journal

IF4.1

2026-01-020

OAAI

New acridone derivatives to target telomerase and oncogenes - an anticancer approach

靶向端粒酶和癌基因的新喹诺酮衍生物——一种抗癌方法

RSC MEDICINAL CHEMISTRY

IF3.6

2025-01-010

OA

Enhanced detection and molecular modeling of adaptive mutations in SARS-CoV-2 coding and non-coding regions using the c/μ test

VIRUS EVOLUTION

IF4

2024-11-060

OAAI

Oncogenic and telomeric G-quadruplexes: Targets for porphyrin-triphenylphosphonium conjugates

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-10-011

OAAI

Binding Mechanism of the Active Form of Molnupiravir to RdRp of SARS-CoV-2 and Designing Potential Analogues: Insights from Molecular Dynamics Simulations

IF4.3

2024-09-241

OAAI

Elucidating the stabilization mechanism of a K +-depleted c-MYC DNA G-quadruplex in hydrophobic imidazolium-based ionic liquids using spectroscopy coupled with molecular dynamics simulations

JOURNAL OF MOLECULAR LIQUIDS

IF5.2

2024-04-010

OAAI

Novel Inhibitors to MmpL3 Transporter of Mycobacterium tuberculosis by Structure-Based High-Throughput Virtual Screening and Molecular Dynamics Simulations

IF4.3

2024-03-123

OAAI

Appraisals on the chemical characterization and biological potentials of Ranunculus constantinopolitanus extracts using chromatographic, computational, and molecular network approaches

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2023-11-010

PRE

Probing the Activation Mechanisms of Agonist DPI-287 to Delta-Opioid Receptor and Novel Agonists Using Ensemble-Based Virtual Screening with Molecular Dynamics Simulations

IF4.3

2023-08-311

OAAI

Inhibition Mechanism of Anti-TB Drug SQ109: Allosteric Inhibition of TMM Translocation of Mycobacterium Tuberculosis MmpL3 Transporter

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2023-08-177

OAAI

Phenolic compounds as potential adenosine deaminase inhibitors: molecular docking and dynamics simulation coupled with MM-GBSA calculations

酚类化合物作为潜在的腺苷脱氨酶抑制剂: 分子对接和动力学模拟与mm-gbsa计算相结合

IF2.4

2023-07-302

PRE

L-shaped distribution of the relative substitution rate (c/?) observed for SARS-COV-2?s genome, inconsistent with the selectionist theory, the neutral theory and the nearly neutral theory but a near-neutral balanced selection theory: Implication on ?neutralist-selectionist? debate

COMPUTERS IN BIOLOGY AND MEDICINE

IF6.3

2023-02-013

OAAI

To probe the binding of TMPyP4 to c-MYC G-quadruplex with in water and in imidazolium-based ionic liquids using spectroscopy coupled with molecular dynamics simulations

JOURNAL OF MOLECULAR LIQUIDS

IF5.2

2022-11-018

OAAI

Thermodynamic destabilization of azurin by four different tetramethylguanidinium amino acid ionic liquids

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2021-06-0110

OAAI

Mechanistic insight on the remdesivir binding to RNA-Dependent RNA polymerase (RdRp) of SARS-cov-2

关于remdesivir与SARS-cov-2的RNA依赖性RNA聚合酶 (RdRp) 结合的机理见解

COMPUTERS IN BIOLOGY AND MEDICINE

IF6.3

2021-02-0127

OAAI

Effects of Ionic Liquids on Metalloproteins

IF4.6

2021-01-1918

OAAI