Christopher L. Burcham - Publications, H-index & Citations

Christopher L. Burcham

Eli Lilly

20H指数

43论文数

1.3K被引数

收录论文 22

发表时间

Reflecting on barriers to continuous pharmaceutical crystallization 反思连续制药结晶的障碍

NATURE CHEMICAL ENGINEERING

IF0

2025-09-01

PREAI

Aprile, Giovanni; Devos, Cedric; Vetter, Thomas; Capellades, Gerard; Girard, Kevin P.; Burcham, Christopher L.; Bhamidi, Venkateswarlu; Green, Daniel; Stelzer, Torsten; Braatz, Richard D.; Myerson, Allan S.

In-situ wet milling for particle size control in continuous crystallization: Expanding the attainable region

CHEMICAL ENGINEERING SCIENCE

IF4.3

2024-12-01

PREAI

Svoboda, Vaclav; Burcham, Christopher L.; Groh, Jennifer McClary; Johnson, Martin D.; Merritt, Jeremy M.; Myers, Steven S.; Stout, James R.

Pharmaceutical Digital Design: From Chemical Structure through Crystal Polymorph to Conceptual Crystallization Process

CRYSTAL GROWTH & DESIGN

IF3.4

2024-06-24

OAAI

Burcham, Christopher L.; Doherty, Michael F.; Peters, Baron G.; Price, Sarah L.; Salvalaglio, Matteo; Reutzel-Edens, Susan M.; Price, Louise S.; Addula, Ravi Kumar Reddy; Francia, Nicholas; Khanna, Vikram; Zhao, Yongsheng

Enabling technologies for biopharmaceutical process development and manufacturing

CHEMICAL ENGINEERING RESEARCH & DESIGN

IF3.9

2023-10-01

OAAI

Nere, Nandkishor K.; Vergis, James M.; Skliar, Dimitri; Bahr, Matthew N.; Jain, Deepak; Burcham, Christopher L.

Single droplets to particles-size, shape, shell thickness and porosity analyses using X-ray computed tomography

CHEMICAL ENGINEERING SCIENCE

IF4.3

2021-12-01

OAAI

Abdullahi, Hassan; Neoptolemou, Petros; Burcham, Christopher L.; Vetter, Thomas

Continuous In Situ Seed Generation through the Integration of a Mixed Suspension Mixed Product Removal and an Oscillatory Baffled Crystallizer for the Control of Crystal Size Distribution and Polymorphic Form

CRYSTAL GROWTH & DESIGN

IF3.4

2021-11-10

PREAI

Wu, Wei-Lee; Oliva, Joseph A.; Kshirsagar, Shivani; Burcham, Christopher L.; Nagy, Zoltan K.

Cross-Pharma Collaboration for the Development of a Simulation Tool for the Model-Based Digital Design of Pharmaceutical Crystallization Processes (CrySiV)

CRYSTAL GROWTH & DESIGN

IF3.4

2021-10-05

PREAI

Szilagyi, Botond; Wu, Wei-Lee; Eren, Ayse; Mackey, Jaron; Kshirsagar, Shivani; Szilagyi, Emoke; Ostergaard, Iben; Qu, Haiyan; Sinha, Kushal; Mlinar, Laurie; Pohlman, Daniel; Chen, Jie; Nere, Nandkishor; Boukerche, Moussa; Korde, Akshay; Ellis, Ryan; Lovette, Michael; Black, Simon; Jawor-Baczynska, Anna; Li, Huayu; Yang, Bing-Shiou; Irdam, Erwin; Patience, Daniel; McKeown, Rahn; Ketchum, Megan; Green, Daniel A.; Reddy, Venkata Ramana; Polster, Christopher; Burcham, Christopher; Jarmer, Daniel; Merritt, Jeremy Miles; Cote, Aaron; Sirota, Eric; Codan, Lorenzo; Schoell, Jochen; Liu, Yiqing Claire; Girard, Kevin P.; Kulkarni, Samir A.; Yang, Yihui; Quon, Justin L.; Nagy, Zoltan K.

Characterizing the Impact of Spray Dried Particle Morphology on Tablet Dissolution Using Quantitative X-Ray Microscopy

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2021-10-01

PREAI

Zhang, Shawn; Stroud, Paul A.; Zhu, Aiden; Johnson, Michael J.; Lomeo, Joshua; Burcham, Christopher L.; Hinds, Jeremy; Blakely, Kyle Allen-Francis; Walworth, Matthew J.

API Continuous Cooling and Antisolvent Crystallization for Kinetic Impurity Rejection in cGMP Manufacturing

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2021-05-16

PREAI

Johnson, Martin D.; Burcham, Christopher L.; May, Scott A.; Calvin, Joel R.; Groh, Jennifer McClary; Myers, Steven S.; Webster, Luke P.; Roberts, Jeffrey C.; Reddy, Venkata Ramana; Luciani, Carla, V; Corrigan, Aoife P.; Spencer, Richard D.; Moylan, Robert; Boyse, Raymond; Murphy, John D.; Stout, James R.

Iterative model-based experimental design for spherical agglomeration processes 基于迭代模型的球形团聚过程实验设计

AICHE JOURNAL

IF4

2021-02-02

PREAI

Pal, Kanjakha; Szilagyi, Botond; Burcham, Christopher L.; Jarmer, Daniel J.; Nagy, Zoltan K.

Further Understanding of Agglomeration Mechanisms in Spherical Crystallization Systems: Benzoic Acid Case Study

CRYSTAL GROWTH & DESIGN

IF3.4

2019-01-16

PREAI

Pena, Ramon; Jarmer, Daniel J.; Burcham, Christopher L.; Nagy, Zoltan K.

A continuous multi-stage mixed-suspension mixed-product-removal crystallization system with fines dissolution

CHEMICAL ENGINEERING RESEARCH & DESIGN

IF3.9

2018-07-01

OAAI

Acevedo, David; Jarmer, Daniel J.; Burcham, Christopher L.; Polster, Christopher S.; Nagy, Zoltan K.

Continuous Manufacturing in Pharmaceutical Process Development and Manufacturing 制药工艺开发和制造中的连续制造

annual review of chemical and biomolecular engineering

IF0

2018-06-07

126

OAAI

Burcham, Christopher L.; Florence, Alastair J.; Johnson, Martin D.

Process Intensification through Continuous Spherical Crystallization Using an Oscillatory Flow Baffled Crystallizer

CRYSTAL GROWTH & DESIGN

IF3.4

2017-08-09

PREAI

Pena, Ramon; Oliva, Joseph A.; Burcham, Christopher L.; Jarmer, Daniel J.; Nagy, Zoltan K.

Modeling and optimization of spherical agglomeration in suspension through a coupled population balance model 基于耦合种群平衡模型的悬浮体球形团聚建模与优化

CHEMICAL ENGINEERING SCIENCE

IF4.3

2017-08-01

PREAI

Pena, Ramon; Burcham, Christopher L.; Jarmer, Daniel J.; Ramkrishna, Doraiswami; Nagy, Zoltan K.

Separation of conglomerate forming enantiomers using a novel continuous preferential crystallization process

AICHE JOURNAL

IF4

2015-08-07

OAAI

Vetter, Thomas; Burcham, Christopher L.; Doherty, Michael F.

Designing Robust Crystallization Processes in the Presence of Parameter Uncertainty Using Attainable Regions

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

IF3.9

2015-06-25

PREAI

Vetter, Thomas; Burcham, Christopher L.; Doherty, Michael F.

Pilot-Scale Continuous Production of LY2886721: Amide Formation and Reactive Crystallization

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2014-10-14

PREAI

Polster, Christopher S.; Cole, Kevin P.; Burcham, Christopher L.; Campbell, Bradley M.; Frederick, Andrea L.; Hansen, Marvin M.; Harding, Molly; Heller, Michael R.; Miller, Michael T.; Phillips, Joseph L.; Pollock, Patrick M.; Zaborenko, Nikolay

Regions of attainable particle sizes in continuous and batch crystallization processes

CHEMICAL ENGINEERING SCIENCE

IF4.3

2014-03-01

119

OAAI

Vetter, Thomas; Burcham, Christopher L.; Doherty, Michael F.

Particle Engineering: A Strategy for Establishing Drug Substance Physical Property Specifications During Small Molecule Development

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2010-01-01

PREAI

Iacocca, Ronald G.; Burcham, Christopher L.; Hilden, Lori R.

研究方向