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Transcriptional Profiling of a Patient-Matched Cohort of Glioblastoma (IDH-Wildtype) for Therapeutic Target and Repurposing Drug Identification 胶质母细胞瘤患者匹配队列 (IDH-野生型) 的转录谱，用于治疗靶标和再利用药物鉴定 Roddy, Aideen C.; McInerney, Caitriona E.; Flannery, Tom; Healy, Estelle G.; Stewart, James P.; Spence, Veronica J.; Walsh, Jamie; Salto-Tellez, Manuel; McArt, Darragh G.; Prise, Kevin M. 分享 收藏
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Evolutionary genetic algorithm identifies IL2RB as a potential predictive biomarker for immune-checkpoint therapy in colorectal cancer Alderdice, Matthew; Craig, Stephanie G.; Humphries, Matthew P.; Gilmore, Alan; Johnston, Nicole; Bingham, Victoria; Coyle, Vicky; Senevirathne, Seedevi; Longley, Daniel B.; Loughrey, Maurice B.; McQuaid, Stephen; James, Jacqueline A.; Salto-Tellez, Manuel; Lawler, Mark; McArt, Darragh G. 分享 收藏
RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer Khawaja, Hajrah; Campbell, Andrew; Roberts, Jamie Z.; Javadi, Arman; O'Reilly, Paul; McArt, Darragh; Allen, Wendy L.; Majkut, Joanna; Rehm, Markus; Bardelli, Alberto; Di Nicolantonio, Federica; Scott, Christopher J.; Kennedy, Richard; Vitale, Nicolas; Harrison, Timothy; Sansom, Owen J.; Longley, Daniel B.; Evergren, Emma; Van Schaeybroeck, Sandra 分享 收藏
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classifieRc: An interactive web interface for the molecular classification of colorectal cancer from RNA-sequencing data Quinn, Gerard; Sessler, Tamas; Allen, Wendy; Maguire, Sarah; Dunne, Philip; McArt, Darragh; VanSteenhouse, Harper; Gallagher, Peter; Lees, Andrea; Longley, Dan; Seligmann, Bruce; Wappett, Mark; McDade, Simon 分享 收藏
Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia Craig, Stephanie G.; Humphries, Matthew P.; Alderdice, Matthew; Bingham, Victoria; Richman, Susan D.; Loughrey, Maurice B.; Coleman, Helen G.; Viratham-Pulsawatdi, Amelie; McCombe, Kris; Murray, Graeme I.; Blake, Andrew; Domingo, Enric; Robineau, James; Brown, Louise; Fisher, David; Seymour, Matthew T.; Quirke, Phil; Bankhead, Peter; McQuaid, Stephen; Lawler, Mark; McArt, Darragh G.; Maughan, Tim S.; James, Jacqueline A.; Salto-Tellez, Manuel 分享 收藏
NUQA: Estimating Cancer Spatial and Temporal Heterogeneity and Evolution through Alignment-Free Methods Roddy, Aideen C.; Jurek-Loughrey, Anna; Souza, Jose; Gilmore, Alan; O'Reilly, Paul G.; Stupnikov, Alexey; de Castro, David Gonzalez; Prise, Kevin M.; Salto-Tellez, Manuel; McArt, Darragh G. 分享 收藏
Artificial intelligence approach identifies IL2RB as a common prognostic and potential predictive biomarker associated with immune checkpoints in colorectal cancer Alderdice, Matthew; Craig, Stephanie; Humphries, Matt; Gilmore, Alan; Bingham, Victoria; Johnston, Nicole; McQuaid, Stephen; Salto-Tellez, Manuel; Lawler, Mark; McArt, Darragh G. 分享 收藏
RALB GTPase: A critical regulator of DR5 cell surface expression and TRAIL sensitivity in RAS mutant colorectal cancer Khawaja, Hajrah; Roberts, Jamie Z.; Javadi, Arman; O'Reilly, Paul; McArt, Darragh; Allen, Wendy L.; Morrison, Markus; Kennedy, Richard; Vitale, Nicolas; Johnston, Patrick G.; Harrison, Tim; Longley, Daniel B.; Evergren, Emma; Van Schaeybroeck, Sandra 分享 收藏
ACE: A Workbench Using Evolutionary Genetic Algorithms for Analyzing Association in TCGA Gilmore, Alan R.; Alderdice, Matthew; Savage, Kienan, I; O'Reilly, Paul G.; Roddy, Aideen C.; Dunne, Philip D.; Lawler, Mark; McDade, Simon S.; Waugh, David J.; McArt, Darragh G. 分享 收藏
Advancing the molecular understanding of stage I colorectal cancer Dunne, Philip; Loughrey, M. B.; Coleman, H. G.; McBride, R.; Campbell, J.; Alderdice, M.; Redmond, K. L.; Mcart, D. G.; Isella, C.; Leedham, S.; Maughan, T.; Lawler, M. 分享 收藏
p53 activation induces a targetable dependence on FLIPL McIntyre, Alexander; Lees, Andrea; Falcone, Fiammetta; Gregg, Gemma; Tamas, Sessler; Quinn, Gerard; Crawford, Nyree; McArt, Darragh; Dunne, Phillip; Lawler, Mark; Daniel, Longley B.; McDade, Simon S. 分享 收藏
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Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer 局限性前列腺癌28基因缺氧相关预后标记的开发和验证 Yang, Lingjian; Roberts, Darren; Takhar, Mandeep; Erho, Nicholas; Bibby, Becky A. S.; Thiruthaneeswaran, Niluja; Bhandari, Vinayak; Cheng, Wei-Chen; Haider, Syed; McCorry, Amy M. B.; McArt, Darragh; Jain, Suneil; Alshalalfa, Mohammed; Ross, Ashley; Schaffer, Edward; Den, Robert B.; Karnes, R. Jeffrey; Klein, Eric; Hoskin, Peter J.; Freedland, Stephen J.; Lamb, Alastair D.; Neal, David E.; Buffa, Francesca M.; Bristow, Robert G.; Boutros, Paul C.; Davicioni, Elai; Choudhury, Ananya; West, Catharine M. L. 分享 收藏
Depletion of DNMT1 in differentiated human cells highlights key classes of sensitive genes and an interplay with polycomb repression O'Neill, Karla M.; Irwin, Rachelle E.; Mackin, Sarah-Jayne; Thursby, Sara-Jayne; Thakur, Avinash; Bertens, Ciske; Masala, Laura; Loughery, Jayne E. P.; McArt, Darragh G.; Walsh, Colum P. 分享 收藏
Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies 前瞻性患者分层为来自结直肠癌活检的强大癌细胞内在亚型 Alderdice, Matthew; Richman, Susan D.; Gollins, Simon; Stewart, James P.; Hurt, Chris; Adams, Richard; McCorry, Amy M. B.; Roddy, Aideen C.; Vimalachandran, Dale; Isella, Claudio; Medico, Enzo; Maughan, Tim; McArt, Darragh G.; Lawler, Mark; Dunne, Philip D. 分享 收藏
Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy Jain, S.; Lyons, C. A.; Walker, S. M.; McQuaid, S.; Hynes, S. O.; Mitchell, D. M.; Pang, B.; Logan, G. E.; McCavigan, A. M.; O'Rourke, D.; McArt, D. G.; McDade, S. S.; Mills, I. G.; Prise, K. M.; Knight, L. A.; Steele, C. J.; Medlow, P. W.; Berge, V.; Katz, B.; Loblaw, D. A.; Harkin, D. P.; James, J. A.; O'Sullivan, J. M.; Kennedy, R. D.; Waugh, D. J. 分享 收藏
Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer 综合肿瘤识别和自动评分最大限度地减少了病理学家的参与，并为乳腺癌的关键生物标志物提供了新的见解 Bankhead, Peter; Fernandez, Jose A.; McArt, Darragh G.; Boyle, David P.; Li, Gerald; Loughrey, Maurice B.; Irwin, Gareth W.; Harkin, D. Paul; James, Jacqueline A.; McQuaid, Stephen; Salto-Tellez, Manuel; Hamilton, Peter W. 分享 收藏
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