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Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs) Pradhan, Balaram; Pavan, Matteo; Fisher, Courtney L.; Salmaso, Veronica; Wan, Tina C.; Keyes, Robert F.; Rollison, Noah; Suresh, R. Rama; Kumar, T. Santhosh; Gao, Zhan-Guo; Smith, Brian C.; Auchampach, John A.; Jacobson, Kenneth A. 分享 收藏
Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A2A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors Kim, Gibae; Jarhad, Dnyandev B.; Lee, Grim; Kim, Gyudong; Hou, Xiyan; Yu, Jinha; Lee, Chang Soo; Warnick, Eugene; Gao, Zhan-Guo; Ahn, Sang Yeop; Kwak, Dongik; Park, Kichul; Lee, Summer Dabin; Park, Tae-uk; Jung, So-young; Lee, Jong Hyun; Choi, Jong-Ryoul; Kim, Myeongjoong; Kim, Donghyun; Kim, Bongtae; Jacobson, Kenneth A.; Jeong, Lak Shin 分享 收藏
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Terpenes from Cannabis sativa induce antinociception in a mouse model of chronic neuropathic pain via activation of adenosine A2A receptors Schwarz, Abigail M.; Keresztes, Attila; Bui, Thai; Hecksel, Ryan; Pena, Adrian; Lent, Brianna; Gao, Zhan-Guo; Gamez-Rivera, Martin; Seekins, Caleb A.; Chou, Kerry; Appel, Taylor L.; Jacobson, Kenneth A.; Al-Obeidi, Fahad A.; Streicher, John M. 分享 收藏
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Extrahelical Binding Site for a 1H-Imidazo[4,5-c]quinolin-4-amine A3 Adenosine Receptor Positive Allosteric Modulator on Helix 8 and Distal Portions of Transmembrane Domains 1 and 7S 螺旋8和跨膜结构域1和7s远端的1h-咪唑 [4，5-c]quinolin-4-amine A3腺苷受体正变构调节剂的螺旋外结合位点 Fisher, Courtney L.; Pavan, Matteo; Salmaso, Veronica; Keyes, Robert F.; Wan, Tina C.; Pradhan, Balaram; Gao, Zhan-Guo; Smith, Brian C.; Jacobson, Kenneth A.; Auchampach, John A. 分享 收藏
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The Hepatokine Orosomucoid 2 Mediates Beneficial Metabolic Effects of Bile Acids Lee, Sung Ho; Suh, Ji Ho; Heo, Mi Jeong; Choi, Jong Min; Yang, Yang; Jung, Hyun-Jung; Gao, Zhanguo; Yu, Yongmei; Jung, Sung Yun; Kolonin, Mikhail G.; Cox, Aaron R.; Hartig, Sean M.; Eltzschig, Holger K.; Ju, Cynthia; Moore, David D.; Kim, Kang Ho 分享 收藏
Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A2A/A3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity (vol 66, pg 12249, 2023) Kim, Gibae; Hou, Xiyan; Byun, Woong Sub; Kim, Gyudong; Jarhad, Dnyandev B.; Lee, Grim; Hyun, Young Eum; Yu, Jinha; Lee, Chang Soo; Qu, Shuhao; Warnick, Eugene; Gao, Zhan-Guo; Kim, Ji Yong; Ji, Seunghee; Shin, Hyunwoo; Choi, Jong-Ryoul; Jacobson, Kenneth A.; Lee, Hyuk Woo; Lee, Sang Kook; Jeong, Lak Shin 分享 收藏
2-Amino-5-arylethynyl-thiophen-3-yl-(phenyl)methanones as A1 Adenosine Receptor Positive Allosteric Modulators Oliva, Paola; Suresh, R. Rama; Pasquini, Silvia; Salmaso, Veronica; Will, Edward J.; Tosh, Dilip K.; Gao, Zhan-Guo; Liu, Naili; Gavrilova, Oksana; Vincenzi, Fabrizio; Varani, Katia; Jacobson, Kenneth A. 分享 收藏
Structure activity relationships of 5-HT2B and 5-HT2C serotonin receptor antagonists: N6, C2 and 5′-Modified (N)-methanocarba-adenosine derivatives 5-HT2B和5-HT2C 5-羟色胺受体拮抗剂的结构活性关系: N6，C2和5 ′-修饰的 (N)-甲烷卡巴-腺苷衍生物 Tosh, Dilip K.; Calkins, Maggie M.; Ivancich, Marko S.; Bock, Hailey A.; Campbell, Ryan G.; Lewicki, Sarah A.; Chen, Eric; Gao, Zhan-Guo; Mccorvy, John D.; Jacobson, Kenneth A. 分享 收藏
Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A2A/A3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity Kim, Gibae; Hou, Xiyan; Byun, Woong Sub; Kim, Gyudong; Jarhad, Dnyandev B.; Lee, Grim; Hyun, Young Eum; Yu, Jinha; Lee, Chang Soo; Qu, Shuhao; Warnick, Eugene; Gao, Zhan-Guo; Kim, Ji Yong; Ji, Seunghee; Shin, Hyunwoo; Choi, Jong-Ryoul; Jacobson, Kenneth A.; Lee, Hyuk Woo; Lee, Sang Kook; Jeong, Lak Shin 分享 收藏
Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y14 Receptor Antagonists Wen, Zhiwei; Pramanik, Asmita; Lewicki, Sarah A.; Jung, Young-Hwan; Gao, Zhan-Guo; Randle, John C. R.; Cronin, Chunxia; Chen, Zhoumou; Giancotti, Luigino A.; Whitehead, Gregory S.; Liang, Bruce T.; Breton, Sylvie; Salvemini, Daniela; Cook, Donald N.; Jacobson, Kenneth A. 分享 收藏
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Anionic phospholipids control mechanisms of GPCR-G protein recognition Thakur, Naveen; Ray, Arka P. P.; Sharp, Liam; Jin, Beining; Duong, Alexander; Pour, Niloofar Gopal; Obeng, Samuel; Wijesekara, Anuradha V. V.; Gao, Zhan-Guo; McCurdy, Christopher R. R.; Jacobson, Kenneth A. A.; Lyman, Edward; Eddy, Matthew T. T. 分享 收藏
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Parenteral Exposure of Mice to Ricin Toxin Induces Fatal Hypoglycemia by Cytokine-Mediated Suppression of Hepatic Glucose-6-Phosphatase Expression Pincus, Seth H.; Kyro, Alexi; Maresh, Grace A.; Peters, Tami; Kempa, Jacob; Marcotte, Tamera K.; Gao, Zhanguo; Ye, Jianping; Copie, Valerie; Song, Kejing 分享 收藏
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