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ATR and PKMYT1 Inhibition Resensitizes a Subset of TNBC Patient-Derived Models to Carboplatin, Inducing Mitotic Catastrophe ATR和PKMYT1抑制使部分三阴性乳腺癌患者衍生的模型对卡铂重新敏感，并诱导有丝分裂灾难 Guay, Juliet; Kuasne, Hellen; Chabot, Catherine; Bozek, Kathryn; Majedi, Yasamin; Buchanan, Marguerite; Aguilar-Mahecha, Adriana; Bareke, Eric; Ulmer, Benjamin; Kong, Tim; Yang, Kangning; Liao, Minyan; Elebute, Oluwadara; Guo, Ruining; Monast, Anie; Morin, Genevieve; Huang, Sidong; Park, Morag; Basik, Mark 分享 收藏
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Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring Kuzmin, Elena; Baker, Toby M.; Lesluyes, Tom; Monlong, Jean; Abe, Kento T.; Coelho, Paula P.; Schwartz, Michael; Del Corpo, Joseph; Zou, Dongmei; Morin, Genevieve; Pacis, Alain; Yang, Yang; Martinez, Constanza; Barber, Jarrett; Kuasne, Hellen; Li, Rui; Bourgey, Mathieu; Fortier, Anne-Marie; Davison, Peter G.; Omeroglu, Atilla; Guiot, Marie-Christine; Morris, Quaid; Kleinman, Claudia L.; Huang, Sidong; Gingras, Anne-Claude; Ragoussis, Jiannis; Bourque, Guillaume; Van Loo, Peter; Park, Morag 分享 收藏
Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in Cancer 共靶向CDK4/6和BRD4促进癌症的衰老和铁死亡敏感性 Zhu, Xianbing; Fu, Zheng; Dutchak, Kendall; Arabzadeh, Azadeh; Milette, Simon; Steinberger, Jutta; Morin, Genevieve; Monast, Anie; Pilon, Virginie; Kong, Tim; Adams, Bianca N.; Prando Munhoz, Erika; Hosein, Hannah J. B.; Fang, Tianxu; Su, Jing; Xue, Yibo; Rayes, Roni; Sangwan, Veena; Walsh, Logan A.; Chen, Guojun; Quail, Daniela F.; Spicer, Jonathan D.; Park, Morag; Dankort, David; Huang, Sidong 分享 收藏
Loop Ileostomy Closure as a 23-Hour Stay Procedure With Preoperative Efferent Limb Enteral Stimulation: A Randomized Controlled Trial Charbonneau, Janyssa; Morin, Genevieve; Pare, Xavier G.; Frigault, Jonathan; Drolet, Sebastien; Bouchard, Alexandre; Rouleau-Fournier, Francois; Bouchard, Philippe; Thibault, Claude; Letarte, Francois 分享 收藏
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Evolution of large copy number variants in breast cancer through genetic network rewiring Kuzmin, Elena; Monlong, Jean; Bourgey, Mathieu; Lesluyes, Tom; Barker, Toby; Morin, Genevieve; Zou, Dongmei; Schwartz, Michael; Yang, Yang; Pacis, Alain; Martinez, Constanza; Kuasne, Hellen; Fortier, Anne-Marie; Li, Rui; Kleinman, Claudia; Huang, Sidong; van Loo, Peter; Ragoussis, Jiannis; Bourque, Guillaume; Park, Morag 分享 收藏
SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria (vol 12, 5404, 2021) Xue, Yibo; Morris, Jordan L.; Yang, Kangning; Fu, Zheng; Zhu, Xianbing; Johnson, Fraser; Meehan, Brian; Witkowski, Leora; Yasmeen, Amber; Golenar, Tunde; Coatham, Mackenzie; Morin, Genevieve; Monast, Anie; Pilon, Virginie; Fiset, Pierre Olivier; Jung, Sungmi; Gonzalez, Anne V.; Camilleri-Broet, Sophie; Fu, Lili; Postovit, Lynne-Marie; Spicer, Jonathan; Gotlieb, Walter H.; Guiot, Marie-Christine; Rak, Janusz; Park, Morag; Lockwood, William; Foulkes, William D.; Prudent, Julien; Huang, Sidong 分享 收藏
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin Biondini, Marco; Kiepas, Alex; El-Houjeiri, Leeanna; Nis, Matthew G. An; Hsu, Brian E.; Fortier, Anne-Marie; Morin, Genevieve; Martina, Jose A.; Sirois, Isabelle; Aguilar-Mahecha, Adriana; Gruosso, Tina; McGuirk, Shawn; Rose, April A. N.; Tokat, Unal M.; Johnson, Radia M.; Sahin, Ozgur; Bareke, Eric; St-Pierre, Julie; Park, Morag; Basik, Mark; Majewski, Jacek; Puertollano, Rosa; Pause, Arnim; Huang, Sidong; Keler, Tibor; Siegel, Peter M. 分享 收藏
A forward genetic screen identifies modifiers of rocaglate responsiveness Shen, Leo; Pugsley, Lauren; Cencic, Regina; Wang, HanChen; Robert, Francis; Naineni, Sai Kiran; Sahni, Ananya; Morin, Genevieve; Zhang, Wenhan; Nijnik, Anastasia; Porco, John A., Jr.; Langlais, David; Huang, Sidong; Pelletier, Jerry 分享 收藏
SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria Xue, Yibo; Morris, Jordan L.; Yang, Kangning; Fu, Zheng; Zhu, Xianbing; Johnson, Fraser; Meehan, Brian; Witkowski, Leora; Yasmeen, Amber; Golenar, Tunde; Coatham, Mackenzie; Morin, Genevieve; Monast, Anie; Pilon, Virginie; Fiset, Pierre Olivier; Jung, Sungmi; Gonzalez, Anne, V; Camilleri-Broet, Sophie; Fu, Lili; Postovit, Lynne-Marie; Spicer, Jonathan; Gotlieb, Walter H.; Guiot, Marie-Christine; Rak, Janusz; Park, Morag; Lockwood, William; Foulkes, William D.; Prudent, Julien; Huang, Sidong 分享 收藏
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The use of conditionally reprogrammed cells for high throughput screening for novel drug combinations to treat drug resistant triple negative breast cancers Aguilar-Mahecha, Adriana; Chabot, Catherine; Santos-Martinez, Nancy; Darini, Cedric; Hajira, Midhet; Kong, Tim; Morin, Genevieve; Huang, Sidong; Park, Morag; Basik, Mark 分享 收藏
SMARCB1 loss induces druggable cyclinD1deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors Xue, Yibo; Zhu, Xianbing; Meehan, Brian; Venneti, Sriram; Martinez, Daniel; Morin, Genevieve; Maiga, Rayelle, I; Chen, Hongbo; Papadakis, Andreas, I; Johnson, Radia M.; O'Sullivan, Maureen J.; Erdreich-Epstein, Anat; Gotlieb, Walter H.; Park, Morag; Judkins, Alexander R.; Pelletier, Jerry; Foulkes, William D.; Rak, Janusz; Huang, Sidong 分享 收藏
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CD44 Promotes PD-L1 Expression and Its Tumor-Intrinsic Function in Breast and Lung Cancers Kong, Tim; Ahn, Ryuhjin; Yang, Kangning; Zhu, Xianbing; Fu, Zheng; Morin, Genevieve; Bramley, Rachel; Cliffe, Nikki C.; Xue, Yibo; Kuasne, Hellen; Li, Qinghao; Jung, Sungmi; Gonzalez, Anne, V; Camilleri-Broet, Sophie; Guiot, Marie-Christine; Park, Morag; Ursini-Siegel, Josie; Huang, Sidong 分享 收藏
SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer Xue, Yibo; Meehan, Brian; Fu, Zheng; Wang, Xue Qing D.; Fiset, Pierre Olivier; Rieker, Ralf; Levins, Cameron; Kong, Tim; Zhu, Xianbing; Morin, Genevieve; Skerritt, Lashanda; Herpel, Esther; Venneti, Sriram; Martinez, Daniel; Judkins, Alexander R.; Jung, Sungmi; Camilleri-Broet, Sophie; Gonzalez, Anne V.; Guiot, Marie-Christine; Lockwood, William W.; Spicer, Jonathan D.; Agaimy, Abbas; Pastor, William A.; Dostie, Josee; Rak, Janusz; Foulkes, William D.; Huang, Sidong 分享 收藏
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary CDK4/6抑制剂靶向SMARCA4-determined高钙血症性卵巢小细胞癌中的细胞周期蛋白D1缺陷 Xue, Yibo; Meehan, Brian; Macdonald, Elizabeth; Venneti, Sriram; Wang, Xue Qing D.; Witkowski, Leora; Jelinic, Petar; Kong, Tim; Martinez, Daniel; Morin, Genevieve; Firlit, Michelle; Abedini, Atefeh; Johnson, Radia M.; Cencic, Regina; Patibandla, Jay; Chen, Hongbo; Papadakis, Andreas I.; Auguste, Aurelie; de Rink, Iris; Kerkhoven, Ron M.; Bertos, Nicholas; Gotlieb, Walter H.; Clarke, Blaise A.; Leary, Alexandra; Witcher, Michael; Guiot, Marie-Christine; Pelletier, Jerry; Dostie, Josee; Park, Morag; Judkins, Alexander R.; Hass, Ralf; Levine, Douglas A.; Rak, Janusz; Vanderhyden, Barbara; Foulkes, William D.; Huang, Sidong 分享 收藏
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