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收藏Imaging of the Effect of Alcohol-Containing Media on the Performance of Hypromellose Hydrophilic Matrix Tablets: Comparison of Direct Compression and Regular Grades of Polymer
Mawla, Nihad; Hanley, Sarah; Walton, Karl; Kaialy, Waseem; Hussain, Tariq; Ward, Adam; Brown, Jonathan; Conway, Barbara R.; Timmins, Peter; Asare-Addo, Kofi
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收藏IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes
Darwich, Adam S.; Margolskee, Alison; Pepin, Xavier; Aarons, Leon; Galetin, Aleksandra; Rostami-Hodjegan, Amin; Carlert, Sara; Hammarberg, Maria; Hilgendorf, Constanze; Johansson, Pernilla; Karlsson, Eva; Murphy, Donal; Tannergren, Christer; Thorn, Helena; Yasin, Mohammed; Mazuir, Florent; Nicolas, Olivier; Ramusovic, Sergej; Xu, Christine; Pathak, Shriram M.; Korjamo, Timo; Laru, Johanna; Malkki, Jussi; Pappinen, Sari; Tuunainen, Johanna; Dressman, Jennifer; Hansmann, Simone; Kostewicz, Edmund; He, Handan; Heimbach, Tycho; Wu, Fan; Hoft, Carolin; Pang, Yan; Bolger, Michael B.; Huehn, Eva; Lukacova, Viera; Mullin, James M.; Szeto, Ke X.; Costales, Chester; Lin, Jian; McAllister, Mark; Modi, Sweta; Rotter, Charles; Varma, Manthena; Wong, Mei; Mitra, Amitava; Bevernage, Jan; Biewenga, Jeike; Van Peer, Achiel; Lloyd, Richard; Shardlow, Carole; Langguth, Peter; Mishenzon, Irina; Mai Anh Nguyen; Brown, Jonathan; Lennernas, Hans; Abrahamsson, Bertil
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收藏IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results
Margolskee, Alison; Darwich, Adam S.; Pepin, Xavier; Aarons, Leon; Galetin, Aleksandra; Rostami-Hodjegan, Amin; Carlert, Sara; Hammarberg, Maria; Hilgendorf, Constanze; Johansson, Pernilla; Karlsson, Eva; Murphy, Donal; Tannergren, Christer; Thorn, Helena; Yasin, Mohammed; Mazuir, Florent; Nicolas, Olivier; Ramusovic, Sergej; Xu, Christine; Pathak, Shriram M.; Korjamo, Timo; Laru, Johanna; Malkki, Jussi; Pappinen, Sari; Tuunainen, Johanna; Dressman, Jennifer; Hansmanni, Simone; Kostewicz, Edmund; He, Handan; Heimbach, Tycho; Wu, Fan; Hoft, Carolin; Laplanche, Loic; Pang, Yan; Bolger, Michael B.; Huehn, Eva; Lukacova, Viera; Mullin, James M.; Szeto, Ke X.; Costales, Chester; Lin, Jian; McAllister, Mark; Modi, Sweta; Rotter, Charles; Varma, Manthena; Wong, Mei; Mitra, Amitava; Bevernage, Jan; Biewenga, Jeike; Van Peer, Achiel; Lloyd, Richard; Shardlow, Carole; Langguth, Peter; Mishenzon, Irina; Mai Anh Nguyen; Brown, Jonathan; Lennernas, Hans; Abrahamsson, Bertil
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收藏Imaging Dehydration Kinetics of a Channel Hydrate Form of the HIV-1 Attachment Inhibitor Prodrug BMS-663068
Leane, Michael M.; Gamble, John F.; Brown, Jonathan; Hughes, Helen; Crull, George; Engstrom, Josh; Gao, Qi; Bunker, Matt; Rutherford, Sandra; Parker, Andrew; Roberts, Clive J.; Tobyn, Mike
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收藏Compartmental absorption modeling and site of absorption studies to determine feasibility of an extended-release formulation of an HIV-1 attachment inhibitor phosphate ester prodrug
Brown, Jonathan; Chien, Caly; Timmins, Peter; Dennis, Andrew; Doll, Walter; Sandefer, Erik; Page, Richard; Nettles, Richard E.; Zhu, Li; Grasela, Dennis
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收藏Amorphous Drug-PVP Dispersions: Application of Theoretical, Thermal and Spectroscopic Analytical Techniques to the Study of a Molecule With Intermolecular Bonds in Both the Crystalline and Pure Amorphous State
Tobyn, Michael; Brown, Jonathan; Dennis, Andrew B.; Fakes, Michael; Gao, Qi; Gamble, John; Khimyak, Yaroslav Z.; Mcgeorge, Gary; Patel, Chhaya; Sinclair, Wayne; Timmins, Peter; Yin, Shawn
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收藏Enhancement of oral bioavailability of an HIV-attachment inhibitor by nanosizing and amorphous formulation approaches
Fakes, Michael G.; Vakkalagadda, Blisse J.; Qian, Feng; Desikan, Sridhar; Gandhi, Rajesh B.; Lai, Chiajen; Hsieh, Alice; Franchini, Miriam K.; Toale, Helen; Brown, Jonathan
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