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J

John W.M. Creemers

KU Leuven
H指数:47
被引数:8,509

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Furin sustains tumor-promoting signals in KRAS- and BRAF-mutated colorectal cancer by engaging the TGF-β1-COX-2 axis in a reciprocal regulatory network

Furin 通过参与 TGF-β1-COX-2 轴的互惠调控网络，维持 KRAS-和BRAF 突变的结直肠癌中的促癌信号

Oncogene
IF7.3
2026-07-120
PRE
Yiyang Liu; Géraldine Siegfried; Simon Pernot; Zongsheng He; Marta Martin Bornez; Sabine Tejpar; Fanny Castanet; Gregoire Desolneux; Serge Evrard; Torsten Steinmetzer; John W. M. Creemers; Abdel-Majid Khatib
Missense variants in CMS22 patients reveal that PREPL has both enzymatic and nonenzymatic functions

CMS22患者的错义变异表明PREPL具有酶和非酶功能

JCI INSIGHT
IF6.1
2024-09-100
OA
Monnens, Yenthe; Theodoropoulou, Anastasia; Rosier, Karen; Bhalla, Kritika; Mahy, Alexia; Vanhoutte, Roeland; Meulemans, Sandra; Cavani, Edoardo; Antanasijevic, Aleksandar; Lemmens, Irma; Lee, Jennifer A.; Spellicy, Catherine J.; Schroer, Richard J.; Maselli, Ricardo A.; Laverty, Chamindra G.; Agostinis, Patrizia; Pagliarini, David J.; Verhelst, Steven; Marcaida, Maria J.; Rochtus, Anne; Dal Peraro, Matteo; Creemers, John W. M.

研究方向

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S
Sandra Meulemans
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Jeroen Declercq
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Wim J.M. Van de Ven
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Anne White
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Jaak Jaeken
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Stephen O’Rahilly
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