Tatiana Goncharov - Publications, H-index & Citations

Tatiana Goncharov

roche holding

16H指数

27论文数

2.0K被引数

收录论文 22

发表时间

Dissecting NOD2 inflammatory signaling in a Blau syndrome model

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Goncharov, Tatiana; Wang, Lei; Zhang, Hua; Suto, Eric; Webster, Joshua; Vucic, Domagoj

RIP1 inhibition protects retinal ganglion cells in glaucoma models of ocular injury

CELL DEATH AND DIFFERENTIATION

IF15.4

2024-10-24

OAAI

Kim, Bo Kyoung; Goncharov, Tatiana; Archaimbault, Sebastien A.; Roudnicky, Filip; Webster, Joshua D.; Westenskow, Peter D.; Vucic, Domagoj

Simultaneous substrate and ubiquitin modification recognition by bispecific antibodies enables detection of ubiquitinated RIP1 and RIP2

SCIENCE SIGNALING

IF6.6

2024-01-16

OAAI

Goncharov, Tatiana; Komuves, Laszlo G.; Kist, Matthias; Castellanos, Erick R.; Witt, Axel; Fedorova, Anna V.; Izrael-Tomasevic, Anita; Yu, Kebing; Keir, Mary; Matsumoto, Marissa L.; Vucic, Domagoj

Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-12-20

OAAI

Prado-Acosta, Mariano; Jeong, Seihwan; Utrero-Rico, Alberto; Goncharov, Tatiana; Webster, Joshua D.; Holler, Ernst; Morales, George; Dellepiane, Sergio; Levine, John E.; Rothenberg, Michael E.; Vucic, Domagoj; Ferrara, James L. M.

XIAP deletion sensitizes mice to TNF-induced and RIP1-mediated death

CELL DEATH & DISEASE

IF9.6

2023-04-11

OAAI

Witt, Axel; Goncharov, Tatiana; Lee, Yujung Michelle; Kist, Matthias; Dohse, Monika; Eastham, Jeff; Dugger, Debra; Newton, Kim; Webster, Joshua D.; Vucic, Domagoj

Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-07-08

PREAI

den Besten, Willem; Verma, Kshitij; Yamazoe, Sayumi; Blaquiere, Nicole; Phung, Wilson; Izrael-Tomasevic, Anita; Mulvihill, Melinda M.; Helgason, Elizabeth; Prakash, Sumit; Goncharov, Tatiana; Vucic, Domagoj; Dueber, Erin; Fairbrother, Wayne J.; Wertz, Ingrid; Yu, Kebing; Staben, Steven T.

Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury

CELL DEATH & DISEASE

IF9.6

2021-04-07

OAAI

Stark, Kimberly; Goncharov, Tatiana; Varfolomeev, Eugene; Xie, Luke; Ngu, Hai; Peng, Ivan; Anderson, Keith R.; Verschueren, Erik; Choi, Meena; Kirkpatrick, Donald S.; Easton, Amy; Webster, Joshua D.; McKenzie, Brent S.; Vucic, Domagoj; Bingol, Baris

Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death 损伤的RIPK1泛素化使小鼠对TNF毒性和炎性细胞死亡敏感

CELL DEATH AND DIFFERENTIATION

IF15.4

2020-09-30

OAAI

Kist, Matthias; Komuves, Laszlo G.; Goncharov, Tatiana; Dugger, Debra L.; Yu, Charles; Roose-Girma, Merone; Newton, Kim; Webster, Joshua D.; Vucic, Domagoj

RIP1 kinase activity is critical for skin inflammation but not for viral propagation

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2020-01-27

OAAI

Webster, Joshua D.; Kwon, Youngsu C.; Park, Summer; Zhang, Hua; Corr, Nick; Ljumanovic, Nina; Adedeji, Adeyemi O.; Varfolomeev, Eugene; Goncharov, Tatiana; Preston, Jessica; Santagostino, Sara F.; Patel, Snahel; Xu, Min; Maher, Jonathan; McKenzie, Brent S.; Vucic, Domagoj

Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation

CELL REPORTS

IF6.9

2019-05-01

OAAI

Zhang, Jieqiong; Webster, Joshua D.; Dugger, Debra L.; Goncharov, Tatiana; Roose-Girma, Merone; Hung, Jeffrey; Kwon, Youngsu C.; Vucic, Domagoj; Newton, Kim; Dixit, Vishva M.

Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling

MOLECULAR CELL

IF16.6

2018-02-01

OAAI

Goncharov, Tatiana; Hedayati, Stefanie; Mulvihill, Melinda M.; Izrael-Tomasevic, Anita; Zobel, Kerry; Jeet, Surinder; Fedorova, Anna V.; Eidenschenk, Celine; deVoss, Jason; Yu, Kebing; Shaw, Andrey S.; Kirkpatrick, Donald S.; Fairbrother, Wayne J.; Deshayes, Kurt; Vucic, Domagoj

Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death

CELL DEATH AND DIFFERENTIATION

IF15.4

2016-08-12

100

OAAI

de Almagro, M. Cristina; Goncharov, Tatiana; Izrael-Tomasevic, Anita; Duttler, Stefanie; Kist, Matthias; Varfolomeev, Eugene; Wu, Xiumin; Lee, Wyne P.; Murray, Jeremy; Webster, Joshua D.; Yu, Kebing; Kirkpatrick, Donald S.; Newton, Kim; Vucic, Domagoj

Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination 细胞IAP蛋白和LUBAC差异调节坏死体相关的RIP1泛素化

CELL DEATH & DISEASE

IF9.6

2015-06-25

OAAI

de Almagro, M. C.; Goncharov, T.; Newton, K.; Vucic, D.

Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment

BIOCHEMICAL JOURNAL

IF4.3

2015-02-06

PREAI

Varfolomeev, Eugene; Izrael-Tomasevic, Anita; Yu, Kebing; Bustos, Daisy; Goncharov, Tatiana; Belmont, Lisa D.; Masselot, Alexandre; Bakalarski, Corey E.; Kirkpatrick, Donald S.; Vucic, Domagoj

OTUB1 modulates c-IAP1 stability to regulate signalling pathways

EMBO JOURNAL

IF8.3

2013-03-22

107

OAAI

Goncharov, Tatiana; Niessen, Kyle; de Almagro, Maria Cristina; Izrael-Tomasevic, Anita; Fedorova, Anna V.; Varfolomeev, Eugene; Arnott, David; Deshayes, Kurt; Kirkpatrick, Donald S.; Vucic, Domagoj

Activation of NF-kB and MAP kinases by TNF Family Receptors is regulated by cellular IAPs

CANCER RESEARCH

IF16.6

2012-04-01

PREAI

Varfolomeev, Evgeny; Goncharov, Tatiana; Maecker, Heather; Zobel, Kerry; Komuves, Laszlo; Deshayes, Kurt; Vucic, Domagoj

Cellular Inhibitors of Apoptosis Are Global Regulators of NF-κB and MAPK Activation by Members of the TNF Family of Receptors

SCIENCE SIGNALING

IF6.6

2012-03-20

182

PREAI

Varfolomeev, Eugene; Goncharov, Tatiana; Maecker, Heather; Zobel, Kerry; Komuves, Laszlo G.; Deshayes, Kurt; Vucic, Domagoj

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling c-IAP1和UbcH5促进TNF信号转导中RIP1的K11-linked聚泛素化

EMBO JOURNAL

IF8.3

2010-11-26

308

OAAI

Dynek, Jasmin N.; Goncharov, Tatiana; Dueber, Erin C.; Fedorova, Anna V.; Izrael-Tomasevic, Anita; Phu, Lilian; Helgason, Elizabeth; Fairbrother, Wayne J.; Deshayes, Kurt; Kirkpatrick, Donald S.; Vucic, Domagoj

Targeting IAPs: NF-κB signaling pathways play a critical role in IAP antagonist induced apoptosis

CANCER RESEARCH

IF16.6

2010-04-01

PREAI

Varfolomeev, Eugene; Goncharov, Tatiana; Vucic, Domagoj

Orally Bioavailable Antagonists of Inhibitor of Apoptosis Proteins Based on an Azabicyclooctane Scaffold

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-02-19

PREAI

Cohen, Frederick; Alicke, Bruno; Elliott, Linda O.; Flygare, John A.; Goncharov, Tatiana; Keteltas, Stephen F.; Franklin, Matthew C.; Frankovitz, Stacy; Stephan, Jean-Philippe; Tsui, Vickie; Vucic, Domagoj; Wong, Harvey; Fairbrother, Wayne J.

研究方向