未登录 分享 收藏
分享 收藏
3-(3-Azabicyclo[2, 2, 1]heptan-2-yl)-1,2,4-oxadiazoles as Novel Potent DPP-4 Inhibitors to Treat T2DM 3-(3-氮杂双环[2,2,1]庚烷-2-基)-1,2,4-恶二唑作为新型强效DPP-4抑制剂治疗T2DM Zinevich, Tatiana V.; Maslov, Ivan O.; Kirichenko, Olga G.; Shorshnev, Sergey V.; Gureev, Maxim A.; Dolgushin, Fedor M.; Porozov, Yuri B.; Trukhan, Vladimir M. 分享 收藏
Molecular Periphery Design Allows Control of the New Nitrofurans Antimicrobial Selectivity Vinogradova, Lyubov; Lukin, Alexey; Komarova, Kristina; Zhuravlev, Maxim; Fadeev, Artem; Chudinov, Mikhail; Rogacheva, Elizaveta; Kraeva, Lyudmila; Gureev, Maxim; Porozov, Yuri; Dogonadze, Marine; Vinogradova, Tatiana 分享 收藏
The Nitrofuran-Warhead-Equipped Spirocyclic Azetidines Show Excellent Activity against Mycobacterium tuberculosis Komarova, Kristina; Vinogradova, Lyubov; Lukin, Alexey; Zhuravlev, Maxim; Deniskin, Dmitry; Chudinov, Mikhail; Gureev, Maxim; Dogonadze, Marine; Zabolotnykh, Natalia; Vinogradova, Tatiana; Lavrova, Anastasia; Yablonskiy, Petr 分享 收藏
The Potential of Usnic-Acid-Based Thiazolo-Thiophenes as Inhibitors of the Main Protease of SARS-CoV-2 Viruses Yarovaya, Olga I.; Filimonov, Aleksandr S.; Baev, Dmitriy S.; Borisevich, Sophia S.; Zaykovskaya, Anna V.; Chirkova, Varvara Yu.; Marenina, Mariya K.; Meshkova, Yulia V.; Belenkaya, Svetlana V.; Shcherbakov, Dmitriy N.; Gureev, Maxim A.; Luzina, Olga A.; Pyankov, Oleg V.; Salakhutdinov, Nariman F.; Khvostov, Mikhail V. 分享 收藏
Novel 1,2,4-Triazole- and Tetrazole-Containing 4H-Thiopyrano[2,3-b]quinolines: Synthesis Based on the Thio-Michael/aza-Morita-Baylis-Hillman Tandem Reaction and Investigation of Antiviral Activity 新型1,2，含4-三唑和四唑的4h-噻喃并 [2，3-b] 喹啉: 基于thio-michael/aza-morita-baylis-hillman串联反应的合成和抗病毒活性的研究 Khramchikhin, Andrey V.; Skryl'nikova, Mariya A.; Gureev, Maxim A.; Zarubaev, Vladimir V.; Esaulkova, Iana L.; Ilyina, Polina A.; Mammeri, Oussama Abdelhamid; Spiridonova, Dar'ya V.; Porozov, Yuri B.; Ostrovskii, Vladimir A. 分享 收藏
分享 收藏
Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos Chen, Deng; Osipyan, Angelina; Adriana, Jeaunice; Kader, Mohammed; Gureev, Maxim; Knol, Catharina W. J.; Sigmund, Marie-Catherine; Xiao, Zhangping; van der Wouden, Petra E.; Cool, Robbert H.; Poelarends, Gerrit J.; Dekker, Frank J. 分享 收藏
分享 收藏
分享 收藏
Novel [1,2,4]triazolo[3,4-b][1,3,4]thiadiazine and [1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine Derivatives: Synthesis, Anti-Viral In Vitro Study and Target Validation Activity 新型 [1,2，4] 三唑并 [3，4-b][1,3，4] 噻二嗪和 [1,2，4] 三唑并 [3，4-b][1,3，4] 噻二氮杂衍生物: 合成，抗病毒体外研究和目标验证活性 Khramchikhin, Andrey, V; Skryl'nikova, Mariya A.; Esaulkova, Iana L.; Sinegubova, Ekaterina O.; Zarubaev, Vladimir V.; Gureev, Maxim A.; Puzyk, Aleksandra M.; Ostrovskii, Vladimir A. 分享 收藏
分享 收藏
Novel 5-Nitrofuran-Tagged Imidazo-Fused Azines and Azoles Amenable by the Groebke-Blackburn-Bienayme Multicomponent Reaction: Activity Profile against ESKAPE Pathogens and Mycobacteria Sapegin, Alexander; Rogacheva, Elizaveta; Kraeva, Lyudmila; Gureev, Maxim; Dogonadze, Marine; Vinogradova, Tatiana; Yablonsky, Petr; Balalaie, Saeed; Baykov, Sergey, V; Krasavin, Mikhail 分享 收藏
Borneol Ester Derivatives as Entry Inhibitors of a Wide Spectrum of SARS-CoV-2 Viruses Yarovaya, Olga I.; Shcherbakov, Dmitriy N.; Borisevich, Sophia S.; Sokolova, Anastasiya S.; Gureev, Maxim A.; Khamitov, Edward M.; Rudometova, Nadezda B.; Zybkina, Anastasiya V.; Mordvinova, Ekaterina D.; Zaykovskaya, Anna V.; Rogachev, Artem D.; Pyankov, Oleg V.; Maksyutov, Rinat A.; Salakhutdinov, Nariman F. 分享 收藏
5-(Sulfamoyl)thien-2-yl 1,3-oxazole inhibitors of carbonic anhydrase II with hydrophilic periphery Kalinin, Stanislav; Kovalenko, Alexander; Valtari, Annika; Nocentini, Alessio; Gureev, Maxim; Urtti, Arto; Korsakov, Mikhail; Supuran, Claudiu T.; Krasavin, Mikhail 分享 收藏
Design, Synthesis and Biological Evaluation of Neogliptin, a Novel 2-Azabicyclo[2.2.1]heptane-Based Inhibitor of Dipeptidyl Peptidase-4 (DPP-4) Maslov, Ivan O.; Zinevich, Tatiana, V; Kirichenko, Olga G.; Trukhan, Mikhail, V; Shorshnev, Sergey, V; Tuaeva, Natalya O.; Gureev, Maxim A.; Dahlen, Amelia D.; Porozov, Yuri B.; Schioth, Helgi B.; Trukhan, Vladimir M. 分享 收藏
Simulation of Molecular Dynamics of SARS-CoV-2 S-Protein in the Presence of Multiple Arbidol Molecules: Interactions and Binding Mode Insights 在多个Arbidol分子存在下SARS-CoV-2 S蛋白的分子动力学模拟: 相互作用和结合模式的见解 Borisevich, Sophia S.; Khamitov, Edward M.; Gureev, Maxim A.; Yarovaya, Olga I.; Rudometova, Nadezhda B.; Zybkina, Anastasiya V.; Mordvinova, Ekaterina D.; Shcherbakov, Dmitriy N.; Maksyutov, Rinat A.; Salakhutdinov, Nariman F. 分享 收藏
A Novel Phenylpyrrolidine Derivative: Synthesis and Effect on Cognitive Functions in Rats with Experimental Ishemic Stroke Borozdenko, Denis A.; Ezdoglian, Aiarpi A.; Shmigol, Tatiana A.; Gonchar, Darya, I; Lyakhmun, Dmitri N.; Tarasenko, Dmitri, V; Golubev, Yaroslav, V; Cherkashova, Elvira A.; Namestnikova, Daria D.; Gubskiy, Ilya L.; Lagunin, Alexey A.; Gubsky, Leonid, V; Chekhonin, Vladimir P.; Borisevich, Sophia S.; Gureev, Maxim A.; Shagina, Anastasia D.; Kiseleva, Nina M.; Negrebetsky, Vadim V.; Baukov, Yuri, I 分享 收藏
π-π Noncovalent Interaction Involving 1,2,4-and 1,3,4-Oxadiazole Systems: The Combined Experimental, Theoretical, and Database Study 涉及1,2，4-和1,3，4-恶二唑系统的 π-π 非共价相互作用: 结合实验，理论和数据库研究 Baykov, Sergey, V; Mikherdov, Alexander S.; Novikov, Alexander S.; Geyl, Kirill K.; Tarasenko, Marina, V; Gureev, Maxim A.; Boyarskiy, Vadim P. 分享 收藏
.png){kind=icon}
.png){kind=icon}
.png)
MOLECULES.png)
OAAI
.png){kind=icon}
分享.png){kind=icon}
收藏