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K

Klaus Pors

University of Bradford

23H指数
130论文数
1.3K被引数
收录论文 51
发表时间
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Comprehensive proteome profiling of cytochrome P450 isoforms in cancer models癌症模型中细胞色素P450异构体的全面蛋白质组分析
errClinical Proteomics
IF3.3
err2025-11-02
err0
errOAAI
errSadr ul Shaheed; Ahood A. Al-Eidan; Klaus Pors; Laurence Patterson; Chris W. Sutton
err分享
err收藏
Cancer stem cells in focus: Deciphering the dynamic functional landscape of stemness in cancer癌症干细胞研究聚焦：解析癌症中干性的动态功能景观
errbiochimica et biophysica acta reviews on cancer
IF0
err2025-09-03
err0
errOAAI
errGabriel C. Nwokolo; Trivadi Sundaram Ganesan; Klaus Pors; Robert A. Falconer; Sneha Smarakan
err分享
err收藏
Discovery of a reversible ALDH1A3 inhibitor throwugh a consensus docking-based virtual screening study通过基于共识对接的虚拟筛选研究发现的可逆性ALDH1A3抑制剂
errJournal of Computer-Aided Molecular Design
IF3.1
err2025-08-31
err0
errOAAI
errE. Batlle; R. Pequerul; J. Farrés; L. A. Eriksson; K. Pors; V. Jha
err分享
err收藏
Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer3-羟基苯并异恶唑衍生物作为醛酮还原酶1C3 (AKR1C3) 抑制剂靶向前列腺癌的结构指导优化
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-03-01
err4
errOAAI
errPippione, Agnese Chiara; Kovachka, Sandra; Vigato, Chiara; Bertarini, Laura; Mannella, Iole; Sainas, Stefano; Rolando, Barbara; Denasio, Enrica; Piercy-Mycock, Helen; Romalho, Linda; Salladini, Edoardo; Adinolfi, Salvatore; Zonari, Daniele; Peraldo-Neia, Caterina; Chiorino, Giovanna; Passoni, Alice; Mirza, Osman Asghar; Frydenvang, Karla; Pors, Klaus; Lolli, Marco Lucio; Spyrakis, Francesca; Oliaro-Bosso, Simonetta; Boschi, Donatella
err分享
err收藏
Investigation to explore how duocarmycin prodrugs bioactivated by cytochrome P450 enzymes can be used in combination therapy to treat breast cancer cells
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errDenasio, Enrica; Shnyder, Steven D.; Morais, Goreti R.; Martin, Stewart G.; Pors, Klaus
err分享
err收藏
New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-07-01
err12
PREAI
errPippione, Agnese Chiara; Kilic-Kurt, Zuhal; Kovachka, Sandra; Sainas, Stefano; Rolando, Barbara; Denasio, Enrica; Pors, Klaus; Adinolfi, Salvatore; Zonari, Daniele; Bagnati, Renzo; Lolli, Marco Lucio; Spyrakis, Francesca; Oliaro-Bosso, Simonetta; Boschi, Donatella
err分享
err收藏
The Chemerin-CMKLR1 Axis is Functionally important for Central Regulation of Energy Homeostasis
errFRONTIERS IN PHYSIOLOGY
IF3.4
err2022-05-30
err15
errOAAI
errYun, Haesung; Dumbell, Rebecca; Hanna, Katie; Bowen, Junior; McLean, Samantha L.; Kantamneni, Sriharsha; Pors, Klaus; Wu, Qing-Feng; Helfer, Gisela
err分享
err收藏
Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-02-25
err11
errOAAI
errIbrahim, Ali I. M.; Batlle, Elisabet; Sneha, Smarakan; Jimenez, Rafael; Pequerul, Raquel; Pares, Xavier; Rungeler, Till; Jha, Vibhu; Tuccinardi, Tiziano; Sadiq, Maria; Frame, Fiona; Maitland, Norman J.; Farres, Jaume; Pors, Klaus
err分享
err收藏
Editorial: Chemical Biology Tools for Peptide and Protein Research
errFRONTIERS IN CHEMISTRY
IF4.2
err2022-02-18
err1
errOAAI
errTsai, Yu-Hsuan; Iwai, Hideo; Pors, Klaus
err分享
err收藏
Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer
errSCIENTIFIC REPORTS
IF3.9
err2021-09-23
err11
errOAAI
errPresa, Daniela; Khurram, Syed A.; Zubir, Amir Z. A.; Smarakan, Sneha; Cooper, Patricia A.; Morais, Goreti R.; Sadiq, Maria; Sutherland, Mark; Loadman, Paul M.; McCaul, James; Shnyder, Steven D.; Patterson, Laurence H.; Pors, Klaus
err分享
err收藏
Design, Synthesis, Biological Evaluation and In Silico Study of Benzyloxybenzaldehyde Derivatives as Selective ALDH1A3 Inhibitors
errMOLECULES
IF4.6
err2021-09-23
err12
errOAAI
errIbrahim, Ali I. M.; Ikhmais, Balqis; Batlle, Elisabet; AbuHarb, Waed K.; Jha, Vibhu; Jaradat, Khaled T.; Jimenez, Rafael; Pequerul, Raquel; Pares, Xavier; Farres, Jaume; Pors, Klaus
err分享
err收藏
Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2021-06-01
err4
errOAAI
errOrtuzar, Natalia; Karu, Kersti; Presa, Daniela; Morais, Goreti R.; Sheldrake, Helen M.; Shnyder, Steve D.; Barnieh, Francis M.; Loadman, Paul M.; Patterson, Laurence H.; Pors, Klaus; Searcey, Mark
err分享
err收藏
Intratumoural Cytochrome P450 Expression in Breast Cancer: Impact on Standard of Care Treatment and New Efforts to Develop Tumour-Selective Therapies肿瘤内细胞色素P450在乳腺癌中的表达: 对护理治疗标准的影响以及开发肿瘤选择性治疗的新努力
errBIOMEDICINES
IF3.9
err2021-03-12
err30
errOAAI
errSneha, Smarakan; Baker, Simon C.; Green, Andrew; Storr, Sarah; Aiyappa, Radhika; Martin, Stewart; Pors, Klaus
err分享
err收藏
How can the potential of the duocarmycins be unlocked for cancer therapy?
errDRUG DISCOVERY TODAY
IF7.5
err2021-02-01
err21
PREAI
errJukes, Zoe; Morais, Goreti Ribeiro; Loadman, Paul M.; Pors, Klaus
err分享
err收藏
Aldehyde Dehydrogenases and Prostate Cancer: Shedding Light on Isoform Distribution to Reveal Druggable Target醛脱氢酶和前列腺癌: 揭示同工型分布以揭示可药靶标
errBIOMEDICINES
IF3.9
err2020-12-04
err10
errOAAI
errQuattrini, Luca; Sadiq, Maria; Petrarolo, Giovanni; Maitland, Norman J.; Frame, Fiona M.; Pors, Klaus; La Motta, Concettina
err分享
err收藏
Multigram scale synthesis of polycyclic lactones and evaluation of antitumor and other biological properties多环内酯的多克尺度合成及抗肿瘤等生物学性能评价
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2020-01-01
err3
errOAAI
errGrau, Laura; Romero, Manel; Privat-Contreras, Cristian; Presa, Daniela; Vinas, Miguel; Morral, Jordi; Pors, Klaus; Rubio-Martinez, Jaime; Dolors Pujol, Maria
err分享
err收藏
Quantitative profiling of Cytochrome P450 2S1 in colorectal cancer by PRM assay
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errul Shaheed, Sadr; Patterson, Laurence H.; Pors, Klaus; Sutton, Chris W.
err分享
err收藏
Synthesis and biological properties of aryl methyl sulfones
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2018-08-01
err19
PREAI
errNavarro, Lorena; Rosell, Gloria; Sanchez, Silvia; Boixareu, Nuria; Pors, Klaus; Pouplana, Ramon; Campanera, Josep M.; Dolors Pujol, M.
err分享
err收藏
Synthesis and biologic evaluation of diethylbenzaldehyde analogues to probe functional activity of aldehyde dehydrogenase activity in cancer
errCANCER RESEARCH
IF16.6
err2018-07-01
err0
PREAI
errIbrahim, Ali; Sadiq, Maria; Presa, Daniela; Ntafoulis, Ioannis; Alkawi, Ahmad; Frame, Fiona; Maitland, Norman J.; Cournia, Zoe; Loadman, Paul M.; Moreb, Jan; Pors, Klaus
err分享
err收藏
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid基于苯并异恶唑部分的有效和选择性的醛酮还原酶1C3 (AKR1C3) 抑制剂: 生物等排支架跳跃方法在氟芬那酸中的应用
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2018-04-01
err50
errOAAI
errPippione, Agnese Chiara; Carnovale, Irene Maria; Bonanni, Davide; Sini, Marcella; Goyal, Parveen; Marini, Elisabetta; Pors, Klaus; Adinolfi, Salvatore; Zonari, Daniele; Festuccia, Claudio; Wahlgren, Weixiao Yuan; Friemann, Rosmarie; Bagnati, Renzo; Boschi, Donatella; Oliaro-Bosso, Simonetta; Lolli, Marco Lucio
err分享
err收藏

研究方向

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