Karel Královec

university of pardubice

H指数:14

被引数:663

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Antimicrobial Activity of Acidifying Hyaluronic Acid–Starch Microfiber Dressings Against Clinical Isolates from Chronic Wounds

酸化透明质酸-淀粉微纤维敷料对临床慢性伤口分离株的抗菌活性

Journal of Functional Biomaterials

IF5.2

2026-03-040

Harmine Derivatives as Anticancer Agents Endowed With Potent and Selective Antileukemia Activity: Synthesis, Biological Evaluation, Proapoptotic and Genotoxic Activity

哈曼因衍生物作为具有强效和选择性抗白血病活性的抗癌剂：合成、生物评价、促凋亡和遗传毒性活性

Archiv der Pharmazie

IF3.6

2026-02-100

OAAI

Antiproliferative activity and apoptosis-inducing mechanism of Amaryllidaceae alkaloid montanine on A549 and MOLT-4 human cancer cells

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2023-10-013

OAAI

Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities

石蒜科生物碱氨苯己碱的半合成衍生物的设计及其体外细胞毒活性的探索

SAUDI PHARMACEUTICAL JOURNAL

IF3.4

2023-08-013

OAAI

Multimodal Contrast Agent Enabling pH Sensing Based on Organically Functionalized Gold Nanoshells with Mn-Zn Ferrite Cores

基于具有mn-zn铁氧体核的有机功能化金纳米壳实现pH传感的多模式造影剂

NANOMATERIALS

IF4.3

2022-01-275

OAAI

Chemical Composition of Natural Hydrolates and Their Antimicrobial Activity on Arcobacter-Like Cells in Comparison with Other Microorganisms

MOLECULES

IF4.6

2020-11-3029

OAAI

Magnetic nanoparticles of Ga-substituted ε-Fe2O3 for biomedical applications: Magnetic properties, transverse relaxivity, and effects of silica-coated particles on cytoskeletal networks

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

IF3.9

2020-03-2410

OAAI

Bersavine: A Novel Bisbenzylisoquinoline Alkaloid with Cytotoxic, Antiproliferative and Apoptosis-Inducing Effects on Human Leukemic Cells

MOLECULES

IF4.6

2020-02-207

OAAI

Scoulerine affects microtubule structure, inhibits proliferation, arrests cell cycle and thus culminates in the apoptotic death of cancer cells

SCIENTIFIC REPORTS

IF3.9

2018-03-1934

OAAI

Synthesis, characterization and in vitro evaluation of substituted N-(2-phenylcyclopropyl)carbamates as acetyl- and butyrylcholinesterase inhibitors

取代的N-(2-苯基环丙基) 氨基甲酸酯作为乙酰胆碱酯酶和丁酰胆碱酯酶抑制剂的合成，表征和体外评估

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2016-08-019

OAAI

Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-irreversible inhibitors

1-[(1R)-1-(6-氟-1，3-苯并噻唑-2-基) 乙基]-3-烷基氨基甲酸酯，新型乙酰胆碱酯酶和丁酰胆碱酯酶假不可逆抑制剂的合成，结构表征，对接，亲脂性和细胞毒性

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-04-0131

PREAI

Comparative cytotoxicity of chelidonine and homochelidonine, the dimethoxy analogues isolated from Chelidonium majus L. (Papaveraceae), against human leukemic and lung carcinoma cells

PHYTOMEDICINE

IF8.3

2016-03-0129

PREAI

The effect of Amaryllidaceae alkaloids haemanthamine and haemanthidine on cell cycle progression and apoptosis in p53-negative human leukemic Jurkat cells

PHYTOMEDICINE

IF8.3

2014-03-0166

PRE

Synthesis and in vitro evaluation of new derivatives of 2-substituted-6-fluorobenzo[d]thiazoles as cholinesterase inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2013-04-0144

PRE

Albumin-coated monodisperse magnetic poly(glycidyl methacrylate) microspheres with immobilized antibodies: Application to the capture of epithelial cancer cells

带有固定抗体的白蛋白包被的单分散磁性聚 (甲基丙烯酸缩水甘油酯) 微球: 用于捕获上皮癌细胞

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

IF3.9

2012-07-0651

PREAI

Karel Královec

个人简介

教育背景

工作经历

荣誉奖项

研究方向