The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven CancersCANCER DISCOVERYIF33.32024-04-192OAAI
NST-628 is a novel, potent, fully brain-penetrant MAPK pathway molecular glue that inhibits RAS- and RAF-driven cancersCANCER RESEARCHIF16.62024-04-050PRE
NST-628 is a novel molecular glue that inhibits signaling and pathway reactivation in oncogenic RAS-MAPK cancersMOLECULAR CANCER THERAPEUTICSIF5.52023-12-011PRE
Monitoring GAPDH activity and inhibition with cysteine-reactive chemical probesRSC CHEMICAL BIOLOGYIF3.12022-01-012OAAI
The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of CancerJOURNAL OF MEDICINAL CHEMISTRYIF6.82021-03-2320PRE
Reaction Coupling between Wild-Type and Disease-Associated Mutant EZH2ACS CHEMICAL BIOLOGYIF3.82014-08-2830PREAI
Convergent evolution of chromatin modification by structurally distinct enzymes: comparative enzymology of histone H3 Ly27 methylation by human polycomb repressive complex 2 and vSETBIOCHEMICAL JOURNALIF4.32013-06-284PREAI
个人简介
教育背景
工作经历
荣誉奖项
未登录.png){kind=icon}
未登录个人简介教育背景工作经历荣誉奖项
研究方向