Manar G. Helal

Mansoura University

H指数:13

被引数:522

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Ivabradine Attenuates Experimental Hepatic Fibrosis by Modulating Inflammatory and Apoptotic Signaling Pathways

伊伐布雷定通过调节炎症和凋亡信号通路减轻实验性肝纤维化

Pharmaceuticals

IF4.8

2026-03-300

OAAI

Targeting the underlying immune mechanism of diabetes-induced myocardial dysfunction via modulation of SIRT-3/p53/TIGAR/PFKFB-3 and SIRT-3/NF-κB signaling pathways as a potential controlling strategy

靶向糖尿病诱导的心肌功能障碍的潜在调控策略，通过调节SIRT-3/p53/TIGAR/PFKFB-3和SIRT-3/NF-κB信号通路以干预其内在免疫机制。

Biomedicine & Pharmacotherapy

IF7.5

2026-01-060

OAAI

Corrigendum to “Dose-dependent renoprotective impact of Lactoferrin against glycerol-induced rhabdomyolysis and acute kidney injury” [Life Sci. 302 (2022) 120646]

勘误：“Lactoferrin对甘油诱导的横纹肌溶解和急性肾损伤的剂量依赖性肾保护作用”[Life Sci. 302 (2022) 120646]

Life Sciences

IF5.1

2025-11-140

PRE

Edaravone protects against cuprizone-induced demyelination in rats by modulating TNF-α/NF-ĸB/NLRP3 signaling and the kynurenine pathway

edaravone通过调节TNF-α/NF-ĸB/NLRP3信号通路和色氨酸通路，保护大鼠免受cuprizone诱导的脱髓鞘损伤。

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2025-07-010

PRE

Protective effect of Dulaglutide, a GLP1 agonist, on acetic acid-induced ulcerative colitis in rats: involvement of GLP-1, TFF-3, and TGF-β/PI3K/NF-κB signaling pathway

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

IF3.1

2024-11-230

OAAI

Renoprotective effect of diacetylrhein on diclofenac-induced acute kidney injury in rats via modulating Nrf2/NF-κB/NLRP3/GSDMD signaling pathways

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2024-05-012

PRE

Inhibitory effect of diacerein on diclofenac-induced acute nephrotoxicity in rats via modulating SIRT1/HIF-1α/NF-κB and SIRT1/p53 regulatory axes

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2024-04-014

PRE

Tiron ameliorates acetic acid-induced colitis in rats: Role of TGF-β/EGFR/ PI3K/NF-κB signaling pathway

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2024-02-010

PRE

Artificial neural network approach for prediction of AuNPs biosynthesis by Streptomyces flavolimosus, characterization, antitumor potency in-vitro and in-vivo against Ehrlich ascites carcinoma

SCIENTIFIC REPORTS

IF3.9

2023-08-0411

OAAI

Eicosapentaenoic acid mitigates ulcerative colitis-induced by acetic acid through modulation of NF-κB and TGF-β/EGFR signaling pathways

LIFE SCIENCES

IF5.1

2023-08-0113

PRE

Nifuroxazide modulates hepatic expression of LXRs/SR-BI/CES1/CYP7A1 and LDL-R and attenuates experimentally-induced hypercholesterolemia and the associated cardiovascular complications

LIFE SCIENCES

IF5.1

2022-10-016

PRE

Dose-dependent renoprotective impact of Lactoferrin against glycerol-induced rhabdomyolysis and acute kidney injury

LIFE SCIENCES

IF5.1

2022-08-0110

PRE

Indapamide Increases IRS1 Expression and Modifies Adiponectin/NLRP3/PPARγ Crosstalk in Type 2 Diabetic Rats

ANTIOXIDANTS

IF6.6

2022-03-319

OAAI

Diacerein versus adipoRon as adiponectin modulators in experimentally-induced end-stage type 2 diabetes mellitus in rats

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

IF4.2

2022-02-018

PRE

Nifuroxazide mitigates cholestatic liver injury by synergistic inhibition of Il-6/B-catenin signaling and enhancement of BSEP and MDRP2 expression

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2021-10-015

PREAI

Saxagliptin defers thioacetamide-induced hepatocarcinogenesis in rats: A novel suppressive impact on Wnt/Hedgehog/Notch1 signaling

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

IF4.2

2021-08-013

PREAI

Potential anti-inflammatory effect of dapagliflozin in HCHF diet-induced fatty liver degeneration through inhibition of TNF-α, IL-1β, and IL-18 in rat liver

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2020-09-0138

PREAI

Tranilast attenuates methotrexate-induced renal and hepatic toxicities: Role of apoptosis-induced tissue proliferation

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

IF2.8

2020-02-1111

PREAI

Irbesartan mitigates acute liver injury, oxidative stress, and apoptosis induced by acetaminophen in mice

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

IF2.8

2020-01-2223

PREAI

Saxagliptin mitigates airway inflammation in a mouse model of acute asthma via modulation of NF-kB and TLR4

LIFE SCIENCES

IF5.1

2019-12-0147

PREAI

Manar G. Helal

个人简介

教育背景

工作经历

荣誉奖项

研究方向