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T

Thomas Christoph

nih national cancer institute (nci)

H指数:32

被引数:3,544

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A novel dual mode-of-action anti-hyperalgesic compound in rats which is neuroprotective and promotes neuroregeneration

一种新型的双重作用模式抗痛觉过敏化合物，具有神经保护作用并促进神经再生

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2022-05-017

PRE

Voltage-gated calcium currents in human dorsal root ganglion neurons

IF5.5

2021-08-2714

OA

In vitro characterization of the thermoneutral transient receptor potential vanilloid-1 (TRPV1) inhibitor GRTE16523

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2020-03-0113

PREAI

Distribution of functional opioid receptors in human dorsal root ganglion neurons

IF5.5

2020-02-2534

OAAI

The nociceptin/orphanin FQ receptor system as a target to alleviate cancer-induced bone pain in rats: Model validation and pharmacological evaluation

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2020-01-216

OAAI

4-Aminophenyl acetamides and propanamides as potent transient receptor potential vanilloid 1 (TRPV1) ligands

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2018-08-014

PREAI

Nociceptin/orphanin FQ opioid peptide (NOP) receptor and μ-opioid peptide (MOP) receptors both contribute to the anti-hypersensitive effect of cebranopadol in a rat model of arthritic pain

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2018-08-0120

PREAI

Selectivity profiling of NOP, MOP, DOP and KOP receptor antagonists in the rat spinal nerve ligation model of mononeuropathic pain

NOP，MOP，DOP和KOP受体拮抗剂在单神经病理性疼痛大鼠脊神经结扎模型中的选择性分析

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2018-05-0114

PREAI

t-Butyl pyridine and phenyl C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2017-04-019

OAAI

Opioid-type Respiratory Depressant Side Effects of Cebranopadol in Rats Are Limited by Its Nociceptin/Orphanin FQ Peptide Receptor Agonist Activity

IF9.1

2017-04-0135

PRE

Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study

IF5.5

2016-10-0178

OAAI

Wodarski, Rachel; Delaney, Ada; Ultenius, Camilla; Morland, Rosie; Andrews, Nick; Baastrup, Catherine; Bryden, Luke A.; Caspani, Ombretta; Christoph, Thomas; Gardiner, Natalie J.; Huang, Wenlong; Kennedy, Jeffrey D.; Koyama, Suguru; Li, Dominic; Ligocki, Marcin; Lindsten, Annika; Machin, Ian; Pekcec, Anton; Robens, Angela; Rotariu, Sanziana M.; Voss, Sabrina; Segerdahl, Marta; Stenfors, Carina; Svensson, Camilla I.; Treede, Rolf-Detlef; Uto, Katsuhiro; Yamamoto, Kazumi; Rutten, Kris; Rice, Andrew S. C.

Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2015-11-017

OAAI

Mechanical hyperalgesia in rats with diabetic polyneuropathy is selectively inhibited by local peripheral nociceptin/orphanin FQ receptor and μ-opioid receptor agonism

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2015-05-0121

PREAI

Pharmacogenomic study of the role of the nociceptin/orphanin FQ receptor and opioid receptors in diabetic hyperalgesia

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2014-10-0112

PREAI

Synthesis and Pharmacological Evaluation of 5-Pyrrolidinylquinoxalines as a Novel Class of Peripherally Restricted κ-Opioid Receptor Agonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-08-0539

PREAI

Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2014-06-2485

OAAI

Discovery of Spiro[cyclohexane-dihydropyrano[3,4-b]indole]-amines as Potent NOP and Opioid Receptor Agonists

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2014-06-2473

OAAI

Cebranopadol: A Novel Potent Analgesic Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonists

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2014-06-01170

PREAI

The Mu-Opioid Receptor Agonist/Noradrenaline Reuptake Inhibition (MOR-NRI) Concept in Analgesia: The Case of Tapentadol

IF7.4

2014-02-2889

PREAI

Lack of synergistic interaction between the two mechanisms of action of tapentadol in gastrointestinal transit

EUROPEAN JOURNAL OF PAIN

IF3.4

2014-02-2614

PREAI