Toshiyuki Kaji - Publications, H-index & Citations

Toshiyuki Kaji

tokyo university of science

24H指数

184论文数

2.1K被引数

收录论文 26

发表时间

Comparative Analysis of Structurally Diverse PFAS-Induced Injury in Vascular Endothelial Cells and Characterization of Necroptosis-Related Cell Death Signaling 结构多样的PFAS诱导血管内皮细胞损伤的对比分析及坏死性凋亡相关细胞死亡信号特征的表征

Toxics

IF4.1

2026-06-12

OAAI

Sayori Ichijo; Toshiyuki Kaji; Tomoya Fujie

Cell Density-Dependent Suppression of Perlecan and Biglycan Expression by Gold Nanocluster in Vascular Endothelial Cells

Cells

IF5.2

2026-01-23

OAAI

Takato Hara; Misato Saeki; Misaki Shirai; Yuichi Negishi; Chika Yamamoto; Toshiyuki Kaji

The Reversible Neurotoxic Effects of Methylmercury on the Dorsal Root Ganglion: Temporal Dynamics in Rats 甲基汞对背根神经节可逆性神经毒性的影响：大鼠中的时间动态

International Journal of Molecular Sciences 2026, Vol. 27, Page 116

IF4.9

2025-12-22

OAAI

Yo Shinoda; Kaito Yamashiro; Ayaka Matsuki; Yuka Sekiguchi; Satoshi Tatsumi; Shino Homma-Takeda; Oki Sekizawa; Marika Abe; Misaki Ozawa; Eiko Yoshida; Yasuhiro Shinkai; Tsutomu Takahashi; Yasuyuki Fujiwara; Toshiyuki Kaji

Extracellular ATP Suppresses Perlecan Core Protein Synthesis via P2Y2 Receptor-Mediated Inhibition of Akt Signaling in Cultured Vascular Endothelial Cells 细胞外ATP通过P2Y2受体介导的Akt信号通路抑制抑制培养的血管内皮细胞中Perlecan核心蛋白的合成

International Journal of Molecular Sciences 2025, Vol. 26, Page 10973

IF4.9

2025-11-15

OAAI

Lihito Ikeuchi; Takato Hara; Kazuki Kitabatake; Fumiaki Uchiumi; Chika Yamamoto; Mitsutoshi Tsukimoto; Tomoya Fujie; Toshiyuki Kaji

Cadmium promotes hyaluronan synthesis by inducing hyaluronan synthase 3 expression in cultured vascular endothelial cells via the c-Jun N-terminal kinase-c-Jun pathway 镉通过诱导c-Jun N末端激酶-c-Jun通路介导的透明质酸合成酶3表达，促进培养的血管内皮细胞中透明质酸的合成。

TOXICOLOGY

IF4.6

2025-02-01

PREAI

Shirai, Misaki; Hara, Takato; Kaji, Toshiyuki; Yamamoto, Chika

Induction of ZIP8, a ZIP transporter, via NF-cB signaling by the activation of IcBa and JNK signaling in cultured vascular endothelial cells exposed to cadmium 镉暴露培养的血管内皮细胞中IcBa和JNK信号的激活通过nf-cb信号传导诱导ZIP转运蛋白ZIP8

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2022-01-01

OAAI

Fujie, Tomoya; Ito, Keisuke; Ozaki, Yusuke; Takahashi, Suzuka; Yamamoto, Chika; Kaji, Toshiyuki

ATP and ADP enhance DNA damage repair in γ-irradiated BEAS-2B human bronchial epithelial cells through activation of P2X7 and P2Y12 receptors

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2020-11-01

OAAI

Kitabatake, Kazuki; Kaji, Toshiyuki; Tsukimoto, Mitsutoshi

Methylmercury promotes prostacyclin release from cultured human brain microvascular endothelial cells via induction of cyclooxygenase-2 through activation of the EGFR-p38 MAPK pathway by inhibiting protein tyrosine phosphatase 1B activity

TOXICOLOGY

IF4.6

2017-12-01

OAAI

Yoshida, Eiko; Kurita, Masaru; Eto, Komyo; Kumagai, Yoshito; Kaji, Toshiyuki

Transforming Growth Factor-1 Modulates the Expression of Syndecan-4 in Cultured Vascular Endothelial Cells in a Biphasic Manner

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2017-04-10

OAAI

Hara, Takato; Yoshida, Eiko; Fujiwara, Yasuyuki; Yamamoto, Chika; Kaji, Toshiyuki

Biglycan Intensifies ALK5-Smad2/3 Signaling by TGF-1 and Downregulates Syndecan-4 in Cultured Vascular Endothelial Cells

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2017-01-10

OAAI

Hara, Takato; Yoshida, Eiko; Shinkai, Yasuhiro; Yamamoto, Chika; Fujiwara, Yasuyuki; Kumagai, Yoshito; Kaji, Toshiyuki

Magnetic resonance imaging of leukoencephalopathy in amnestic workers exposed to organotin 暴露于有机锡的遗忘工人的脑白质病的磁共振成像

NEUROTOXICOLOGY

IF3.9

2016-12-01

PREAI

Lee, Eunmi; Park, Ji Eun; Iida, Mayu; Fujie, Tomoya; Kaji, Toshiyuki; Ichihara, Gaku; Weon, Young Cheol; Kim, Yangho

Invited Article: Generation of one-million-mode continuous-variable cluster state by unlimited time-domain multiplexing

APL PHOTONICS

IF5.3

2016-09-27

193

OAAI

Yoshikawa, Jun-ichi; Yokoyama, Shota; Kaji, Toshiyuki; Sornphiphatphong, Chanond; Shiozawa, Yu; Makino, Kenzo; Furusawa, Akira

Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells

SCIENTIFIC REPORTS

IF3.9

2016-06-30

OAAI

Unoki, Takamitsu; Abiko, Yumi; Toyama, Takashi; Uehara, Takashi; Tsuboi, Koji; Nishida, Motohiro; Kaji, Toshiyuki; Kumagai, Yoshito

Partial contribution of the Keap1-Nrf2 system to cadmium-mediated metallothionein expression in vascular endothelial cells

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2016-03-01

PREAI

Shinkai, Yasuhiro; Kimura, Tomoki; Itagaki, Ayaka; Yamamoto, Chika; Taguchi, Keiko; Yamamoto, Masayuki; Kumagai, Yoshito; Kaji, Toshiyuki

Effects of Chronic Low-Dose Radiation on Human Neural Progenitor Cells

SCIENTIFIC REPORTS

IF3.9

2016-01-22

OAAI

Katsura, Mari; Cyou-Nakamine, Hiromasa; Zen, Qin; Zen, Yang; Nansai, Hiroko; Amagasa, Shota; Kanki, Yasuharu; Inoue, Tsuyoshi; Kaneki, Kiyomi; Taguchi, Akashi; Kobayashi, Mika; Kaji, Toshiyuki; Kodama, Tatsuhiko; Miyagawa, Kiyoshi; Wada, Youichiro; Akimitsu, Nobuyoshi; Sone, Hideko

Heparan sulfate chains potentiate cadmium cytotoxicity in cultured vascular endothelial cells

ARCHIVES OF TOXICOLOGY

IF6.9

2014-11-25

PREAI

Fujiwara, Yasuyuki; Yamamoto, Chika; Yoshida, Eiko; Kumagai, Yoshito; Kaji, Toshiyuki

Ultra-large-scale continuous-variable cluster states multiplexed in the time domain 在时域中多路复用的超大规模连续变量簇状态

NATURE PHOTONICS

IF32.9

2013-11-17

408

PREAI

Yokoyama, Shota; Ukai, Ryuji; Armstrong, Seiji C.; Sornphiphatphong, Chanond; Kaji, Toshiyuki; Suzuki, Shigenari; Yoshikawa, Jun-ichi; Yonezawa, Hidehiro; Menicucci, Nicolas C.; Furusawa, Akira

Bis(L-cysteinato)zincate(II) as a coordination compound that induces metallothionein gene transcription without inducing cell-stress-related gene transcription

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2012-12-01

PREAI

Kimura, Tomoki; Yoshida, Kengo; Yamamoto, Chika; Suzuki, Minako; Uno, Tomoko; Isobe, Masakazu; Naka, Hiroshi; Yasuike, Shuji; Satoh, Masahiko; Kaji, Toshiyuki; Uchiyama, Masanobu

S-Mercuration of rat sorbitol dehydrogenase by methylmercury causes its aggregation and the release of the zinc ion from the active site

ARCHIVES OF TOXICOLOGY

IF6.9

2012-06-30

PREAI

Kanda, Hironori; Toyama, Takashi; Shinohara-Kanda, Azusa; Iwamatsu, Akihiro; Shinkai, Yasuhiro; Kaji, Toshiyuki; Kikushima, Makoto; Kumagai, Yoshito

Lead Induces the Expression of Endoplasmic Reticulum Chaperones GRP78 and GRP94 in Vascular Endothelial Cells via the JNK-AP-1 Pathway

TOXICOLOGICAL SCIENCES

IF4.1

2010-01-13

OAAI

Shinkai, Yasuhiro; Yamamoto, Chika; Kaji, Toshiyuki

研究方向