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Г

Галина Ф. Махаева

postovsky institute of organic synthesis, ural branch of russian academy of sciences
H指数:28
被引数:2,535

个人简介

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教育背景

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工作经历

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荣誉奖项

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Synthesis of Tacrine/Amiridine Conjugates with Aminomethylidene Derivatives of Trifluoroacetoacetic Ester and their Biological Potential for the Therapy of Alzheimer's Disease

合成了他克林/安理申共轭物与三氟乙酰乙酸酯的氨基甲基烯衍生物及其治疗阿尔茨海默病的生物学潜力。

CHEMMEDCHEM
IF3.4
2025-10-011
PRE
Grishchenko, Maria V.; Makhaeva, Galina F.; Burgart, Yanina V.; Kovaleva, Nadezhda V.; Boltneva, Natalia P.; Skornyakova, Tatiana S.; Rudakova, Elena V.; Astakhova, Tatiana Y.; Timokhina, Elena N.; Pronkin, Pavel G.; Shchegolkov, Evgeny V.; Saloutin, Victor; Charushin, Valery N.
2-Arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropanoic acids as selective and effective carboxylesterase inhibitors with powerful antioxidant potential
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2024-12-010
PRE
V. Burgart, Yanina; Makhaeva, Galina F.; Khudina, Olga G.; Krasnykh, Olga P.; V. Kovaleva, Nadezhda; Elkina, Natalia A.; Boltneva, Natalia P.; V. Rudakova, Elena; V. Lushchekina, Sofya; Shchegolkov, Evgeny V.; Triandafilova, Galina A.; Malysheva, Ksenia O.; Serebryakova, Olga G.; Borisevich, Sophia S.; Ilyina, Margarita G.; Zhilina, Ekaterina F.; Saloutin, Victor I.; Charushin, Valery N.; Richardson, Rudy J.
Efficient synthesis and evaluation of therapeutic potential of fluorine containing 2-arylchromen-4-ones

含氟2-芳基色烯-4-酮的有效合成和治疗潜力评估

MOLECULAR DIVERSITY
IF3.8
2024-07-162
PRE
Troshkova, Nadezhda; Politanskaya, Larisa; Wang, Jiaying; Niukalova, Maria; Khasanov, Shokhrukh; Esaulkova, Iana; Zarubaev, Vladimir; Boltneva, Natalia; Rudakova, Elena; Kovaleva, Nadezhda; Serebryakova, Olga; Makhaeva, Galina; Valuisky, Nikita; Ibragimova, Umida; Litvinov, Roman; Babkov, Denis; Usenov, Kubanych; Chertenkov, Matvey; Pokrovsky, Mikhail; Cheresiz, Sergey; Pokrovsky, Andrey
Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease
MOLECULES
IF4.6
2024-01-095
OAAI
Makhaeva, Galina F.; Kovaleva, Nadezhda V.; Rudakova, Elena V.; Boltneva, Natalia P.; Lushchekina, Sofya V.; Astakhova, Tatiana Y.; Timokhina, Elena N.; Serkov, Igor V.; Proshin, Alexey N.; Soldatova, Yuliya V.; Poletaeva, Darya A.; Faingold, Irina I.; Mumyatova, Viktoriya A.; Terentiev, Alexey A.; Radchenko, Eugene V.; Palyulin, Vladimir A.; Bachurin, Sergey O.; Richardson, Rudy J.
Powerful Potential of Polyfluoroalkyl-Containing 4-Arylhydrazinylidenepyrazol-3-ones for Pharmaceuticals
MOLECULES
IF4.6
2022-12-216
OAAI
Burgart, Yanina V. V.; Elkina, Natalia A. A.; Shchegolkov, Evgeny V. V.; Krasnykh, Olga P. P.; Makhaeva, Galina F. F.; Triandafilova, Galina A. A.; Solodnikov, Sergey Yu.; Boltneva, Natalia P. P.; Rudakova, Elena V. V.; Kovaleva, Nadezhda V. V.; Serebryakova, Olga G. G.; Ulitko, Mariya V. V.; Borisevich, Sophia S. S.; Gerasimova, Natalia A. A.; Evstigneeva, Natalia P. P.; Kozlov, Sergey A. A.; Korolkova, Yuliya V. V.; Minin, Artem S. S.; Belousova, Anna V. V.; Mozhaitsev, Evgenii S. S.; Klabukov, Artem M. M.; Saloutin, Victor I. I.
Synthesis of 4-Aminopyrazol-5-ols as Edaravone Analogs and Their Antioxidant Activity

依达拉奉类似物4-氨基吡唑-5-醇的合成及其抗氧化活性

MOLECULES
IF4.6
2022-11-0911
OAAI
Burgart, Yanina, V; Makhaeva, Galina F.; Krasnykh, Olga P.; Borisevich, Sophia S.; Agafonova, Natalia A.; Kovaleva, Nadezhda, V; Boltneva, Natalia P.; Rudakova, Elena, V; Shchegolkov, Evgeny, V; Triandafilova, Galina A.; Gazizov, Denis A.; Serebryakova, Olga G.; Ulitko, Maria, V; Khursan, Sergey L.; Saloutin, Victor, I; Richardson, Rudy J.
Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile

作为乙酰胆碱酯酶和丁酰胆碱酯酶抑制剂的双氨吡啶: N官能化决定了多靶点抗阿尔茨海默氏病的活性

MOLECULES
IF4.6
2022-02-0415
OAAI
Makhaeva, Galina F.; Kovaleva, Nadezhda V.; Boltneva, Natalia P.; Rudakova, Elena V.; Lushchekina, Sofya V.; Astakhova, Tatiana Yu.; Serkov, Igor V.; Proshin, Alexey N.; Radchenko, Eugene V.; Palyulin, Vladimir A.; Korabecny, Jan; Soukup, Ondrej; Bachurin, Sergey O.; Richardson, Rudy J.
Conjugation of Aminoadamantane and γ-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands
MOLECULES
IF4.6
2021-09-1118
OAAI
Bachurin, Sergey O.; Makhaeva, Galina F.; Shevtsova, Elena F.; Aksinenko, Alexey Yu; Grigoriev, Vladimir V.; Shevtsov, Pavel N.; Goreva, Tatiana, V; Epishina, Tatiana A.; Kovaleva, Nadezhda, V; Pushkareva, Elena A.; Boltneva, Natalia P.; Lushchekina, Sofya, V; Gabrelyan, Alexey, V; Zamoyski, Vladimir L.; Dubova, Lyudmila G.; Rudakova, Elena, V; Fisenko, Vladimir P.; Bovina, Elena, V; Richardson, Rudy J.
Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2021-06-0115
PRE
Makhaeva, Galina F.; Lushchekina, Sofya, V; Boltneva, Natalia P.; Serebryakova, Olga G.; Kovaleva, Nadezhda, V; Rudakova, Elena, V; Elkina, Natalia A.; Shchegolkov, Evgeny, V; Burgart, Yanina, V; Stupina, Tatyana S.; Terentiev, Alexey A.; Radchenko, Eugene, V; Palyulin, Vladimir A.; Saloutin, Victor, I; Bachurin, Sergey O.; Richardson, Rudy J.
New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer's Disease Treatment
MOLECULES
IF4.6
2020-12-1239
OAAI
Makhaeva, Galina F.; Kovaleva, Nadezhda, V; Rudakova, Elena, V; Boltneva, Natalia P.; Lushchekina, Sofya, V; Faingold, Irina I.; Poletaeva, Darya A.; Soldatova, Yuliya, V; Kotelnikova, Raisa A.; Serkov, Igor, V; Ustinov, Anatoly K.; Proshin, Alexey N.; Radchenko, Eugene, V; Palyulin, Vladimir A.; Richardson, Rudy J.
Multiple biological active 4-aminopyrazoles containing trifluoromethyl and their 4-nitroso-precursors: Synthesis and evaluation
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2020-12-0121
PREAI
Burgart, Yanina, V; Agafonova, Natalia A.; Shchegolkov, Evgeny, V; Krasnykh, Olga P.; Kushch, Svetlana O.; Evstigneeva, Natalia P.; Gerasimova, Natalia A.; Maslova, Vera V.; Triandafilova, Galina A.; Solodnikov, Sergey Yu; Ulitko, Maria, V; Makhaeva, Galina F.; Rudakova, Elena, V; Borisevich, Sophia S.; Zilberberg, Natalia, V; Kungurov, Nikolai, V; Saloutin, Victor, I; Chupakhin, Oleg N.

研究方向

暂未获取到该数据
N
Natalia P. Boltneva
H 指数:21论文数:104被引数:1,474
Е
Елена В. Рудакова
H 指数:22论文数:154被引数:1,625
N
N. V. Kovaleva
H 指数:19论文数:138被引数:1,288
S
Sofya V. Lushchekina
H 指数:31论文数:143被引数:2,520
R
Rudy J. Richardson
H 指数:37论文数:203被引数:5,965
С
С. О. Бачурин
H 指数:38论文数:292被引数:5,388
O
Olga G. Serebryakova
H 指数:16论文数:55被引数:741
В
В. И. Салоутин
H 指数:25论文数:962被引数:4,016
Y
Yanina V. Burgart
H 指数:23论文数:403被引数:2,725
E
Evgeny V. Shchegolkov
H 指数:17论文数:159被引数:1,004