未登录 Low PD-L1 expression, MAP2K2 alterations, and enriched HPV gene signatures characterize brain metastases in head and neck squamous cell carcinoma Dennis, Michael J.; Pavlick, Dean C.; Kacew, Alec; Wotman, Michael; Macconaill, Laura E.; Jones, Stephanie M.; Pfaff, Kathleen L.; Rodig, Scott J.; Eacker, Stephen; Malig, Maika; Reister, Emily; Piccioni, David; Kesari, Santosh; Sehgal, Kartik; Haddad, Robert I.; Cohen, Ezra; Posner, Marshall R.; Deichaite, Ida; Hanna, Glenn J. 分享 收藏
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Safety profile of pembrolizumab monotherapy based on an aggregate safety evaluation of 8937 patients Brahmer, Julie R.; Long, Georgina, V; Hamid, Omid; Garon, Edward B.; Herbst, Roy S.; Andre, Thierry; Armand, Philippe; Bajorin, Dean; Bellmunt, Joaquim; Burtness, Barbara; Choueiri, Toni K.; Cohen, Ezra E. W.; Diaz Jr, Luis A.; Shitara, Kohei; Kulkarni, Girish; McDermott, David; Shah, Manish; Tabernero, Josep; Vogel, Arndt; Zinzani, Pier Luigi; Jafari, Niusha; Birdu, Steven; Snyderu, Ellen; Gause, Christine; Braccou, Oswaldo L.; Pietanza, M. Catherine; Gruberu, Todd; Ribas, Antoni 分享 收藏
A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer 功能性鉴定平台揭示了癌症患者中频繁的自发新抗原特异性T细胞反应 Miller, Aaron M.; Kosaloglu-Yalcin, Zeynep; Westernberg, Luise; Montero, Leslie; Bahmanof, Milad; Frentzen, Angela; Lanka, Manasa; Premlal, Ashmitaa Logandha Ramamoorthy; Seumois, Gregory; Greenbaum, Jason; Brightman, Spencer E.; Zavala, Karla Soria; Thota, Rukman R.; Naradikian, Martin S.; Makani, Samir S.; Lippman, Scott M.; Sette, Alessandro; Cohen, Ezra E. W.; Peters, Bjoern; Schoenberger, Stephen P. 分享 收藏
Pembrolizumab versus methotrexate, docetaxel, or cetuximab in recurrent or metastatic head and neck squamous cell carcinoma (KEYNOTE-040) : Subgroup analysis by pattern of disease recurrence 帕博利珠单抗与甲氨蝶呤，多西他赛或西妥昔单抗在复发或转移性头颈部鳞状细胞癌中的比较 (KEYNOTE-040): 疾病复发模式的亚组分析 Harrington, K. J.; Cohen, E. E. W.; Soulieres, D.; Dinis, J.; Licitra, L.; Ahn, M. -j.; Soria, A.; Machiels, J. -p.; Mach, N.; Mehra, R.; Burtness, B.; Swaby, R. F.; Lin, J.; Ge, J.; Lerman, N.; Le Tourneau, C. 分享 收藏
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A phase II trial of the IO102-IO103 vaccine plus pembrolizumab: preliminary analysis for first-line (1L) treatment of non-small cell lung cancer (NSCLC) and squamous cell carcinoma of the head and neck (SCCHN) Riess, J. W.; Cohen, E.; Spicer, J.; Shaw, P. H.; Rubio Perez, J.; Medina Rodriguez, L.; Chaney, M. F.; O'Neill, S.; Pedersen, A. W.; McDowell, D.; Ehrnrooth, E.; Lopez, P. Garrido 分享 收藏
ALK fusion detection by RNA next-generation sequencing (NGS) compared to DNA in a large, real-world non-small cell lung cancer (NSCLC) dataset Iams, W.; Ben-Shachar, R.; Gai, L.; Beauchamp, K.; Sharma, N.; Islam, S.; Guinney, J.; Nimeiri, H.; Gentzler, R. D.; Cohen, E. 分享 收藏
PEMDA-HN, an open-label, phase II, randomized controlled study of danvatirsen plus pembrolizumab compared to pembrolizumab alone in recurrent or metastatic head and neck squamous cell carcinoma (RM HNSCC) Saba, N.; Youssoufian, H.; Cohen, E.; Singh, J.; Makris, L.; Perdomini, M.; MacIntyre, S.; Denker, A. 分享 收藏
Linked CD4+/CD8+T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression Dolina, Joseph S.; Lee, Joey; Brightman, Spencer E.; McArdle, Sara; Hall, Samantha M.; Thota, Rukman R.; Zavala, Karla S.; Lanka, Manasa; Premlal, Ashmitaa Logandha Ramamoorthy; Greenbaum, Jason A.; Cohen, Ezra E. W.; Peters, Bjoern; Schoenberger, Stephen P. 分享 收藏
A multicenter, open-label, randomized, phase II study of cediranib with or without lenalidomide in iodine 131-refractory differentiated thyroid cancer Rosenberg, A. J.; Liao, C. -Y.; Karrison, T.; de Souza, J. A.; Worden, F. P.; Libao, B.; Krzyzanowska, M. K.; Hayes, D. N.; Winquist, E.; Saloura, V.; Prescott, K.; Villaflor, V. M.; Seiwert, T. Y.; Schechter, R. B.; Stadler, W. M.; Cohen, E. E. W.; Vokes, E. E. 分享 收藏
Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors (vol 24, pg 1345, 2023) 新抗原特异性干细胞记忆样CD4 T细胞介导MHC II类阴性实体瘤的CD8 T细胞依赖性免疫疗法 (第24卷，1345页，2023页) Brightman, Spencer E.; Becker, Angelica; Thota, Rukman R.; Naradikian, Martin S.; Chihab, Leila; Zavala, Karla Soria; Premlal, Ashmitaa Logandha Ramamoorthy; Griswold, Ryan Q.; Dolina, Joseph S.; Cohen, Ezra E. W.; Miller, Aaron M.; Peters, Bjoern; Schoenberger, Stephen P. 分享 收藏
Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors 新抗原特异性干细胞记忆样CD4 T细胞介导MHC ⅱ 类阴性实体瘤的CD8 T细胞依赖性免疫治疗 Brightman, Spencer E. E.; Becker, Angelica; Thota, Rukman R. R.; Naradikian, Martin S. S.; Chihab, Leila; Zavala, Karla Soria; Griswold, Ryan Q. Q.; Dolina, Joseph S. S.; Cohen, Ezra E. W.; Miller, Aaron M. M.; Peters, Bjoern; Schoenberger, Stephen P. P. 分享 收藏
Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway 人乳头瘤病毒E5通过抑制免疫蛋白酶体和STING途径抑制免疫力 Miyauchi, Sayuri; Kim, Sangwoo S.; Jones, Riley N.; Zhang, Lin; Guram, Kripa; Sharma, Sonia; Schoenberger, Stephen P.; Cohen, Ezra E. W.; Califano, Joseph A.; Sharabi, Andrew B. 分享 收藏
Clinical activity of MCLA-158 (petosemtamab), an IgG1 bispecific antibody targeting EGFR and LGR5, in advanced head and neck squamous cell cancer (HNSCC) Cohen, Ezra E.; Fayette, Jerome; Daste, Amaury; Even, Caroline; Le Tourneau, Christophe; Brana, Irene; Saada, Esma; Fontana, Elisa; Iglesias, Lara; Kato, Shumei; Garcia-Carbonero, Rocio; Tabernero, Josep; Argiles, Guillem; Magin, Marina; Shen, Yu-Ming; de Leeuw, Renee; Bekradda, Mohamed; Pennella, Eduardo; Wasserman, Ernesto; Stalbovskaya, Viktoriya; van Bueren, Jeroen Lammerts; Jain, Lokesh; Joe, Andrew 分享 收藏
Preliminary dose escalation results of ERAS-601 in combination with cetuximab in FLAGSHP-1: a phase I study of ERAS-601, a potent and selective SHP2 inhibitor, in patients with previously treated advanced or metastatic solid tumors McKean, Meredith; Rosen, Ezra; Barve, Minal; Meniawy, Tarek; Wang, Judy; Hong, David S.; Yang, Jennifer; Li, Zhengrong; Picard, Roxana; Brail, Les; Vecchio, Daniela; John, Thomas; Cohen, Ezra; Obara, Gregory; Parikh, Aparna 分享 收藏
Eganelisib, a First-in-Class PI3Kg Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial Eganelisib，一类PI3Kg抑制剂，用于晚期实体瘤患者: 1/1b期MARIO-1试验的结果 Hong, David S.; Postow, Michael; Chmielowski, Bartosz; Sullivan, Ryan; Patnaik, Amita; Cohen, Ezra E. W.; Shapiro, Geoffrey; Steuer, Conor; Gutierrez, Martin; Yeckes-Rodin, Heather; Ilaria Jr, Robert; O'Connell, Brenda; Peng, Joanna; Peng, Guangbin; Zizlsperger, Nora; Tolcher, Anthony; Wolchok, Jedd D. 分享 收藏
Tumor cells fail to present MHC-II-restricted epitopes derived from oncogenes to CD4+T cells 肿瘤细胞不能将源自癌基因的mhc-ii限制性表位呈递给CD4 T细胞 Brightman, Spencer E.; Naradikian, Martin S.; Thota, Rukman R.; Becker, Angelica; Montero, Leslie; Bahmanof, Milad; Premlal, Ashmitaa Logandha Ramamoorthy; Greenbaum, Jason A.; Peters, Bjoern; Cohen, Ezra E. W.; Miller, Aaron M.; Schoenberger, Stephen P. 分享 收藏
A phase I study of avelumab, palbociclib, and cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma Dennis, Michael J.; Sacco, Assuntina G.; Qi, Yuchen; Bykowski, Julie; Pittman, Emily; Chen, Ruifeng; Messer, Karen; Cohen, Ezra E. W.; Gold, Kathryn A. 分享 收藏
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