Prasanna Rajagopalan

College of Applied Medical Sciences

H指数:18

被引数:878

个人简介

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KS79356, a novel kynureninase inhibitor, suppresses triple-negative breast cancer progression by attenuating the TNF-α/NFκB–CD44–Akt signaling axis

KS79356，一种新型色氨酸酶抑制剂，通过减弱TNF-α/NFκB–CD44–Akt信号轴抑制三阴性乳腺癌进展

Medical Oncology

IF3.5

2026-08-290

PRE

Integrated discovery of SBLR876: a potent RAGE inhibitor mitigating AGE–RAGE–NF-κB-mediated cytotoxicity and inflammation in diabetic kidney disease

SBLR876的整合发现：一种强效的RAGE抑制剂，可减轻糖尿病肾病中AGE–RAGE–NF-κB介导的细胞毒性和炎症

Biochemical and Biophysical Research Communications

IF2.2

2026-03-050

PRE

Selectively targeting the IKKβ by 11,11’-methylenebisdibenzo[a, c]phenazine (SIKB-7543) downregulates aberrant NF-κB signaling to control the proliferation and induce apoptosis in Hodgkin lymphoma

通过11,11’-亚甲基双二苯并[a, c]菲嗪（SIKB-7543）选择性靶向IKKβ，下调异常的NF-κB信号通路以控制霍奇金淋巴瘤的增殖并诱导其凋亡。

Medical Oncology

IF3.5

2025-10-160

PRE

Identification of 8-(2-methyl phenyl)-9H-benzo[f]indeno[2,1-c] quinolin-9-one (C-5635020) as a novel and selective TGFβ RII kinase inhibitor for breast cancer therapy

鉴定8-(2-甲基苯基)-9H-苯并[f]吲哚[2,1-c]喹啉-9-酮（C-5635020）为一种新型且选择性的TGFβ RII激酶抑制剂，用于乳腺癌治疗

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IF2.2

2025-02-010

PRE

GC/MS characterization and computational kinome-wide screening of pomegranate fruit extract identifies key phytochemicals interacting to CDK kinases implicated in acute myeloid leukemia cells

JOURNAL OF FOOD BIOCHEMISTRY

IF4.2

2022-04-223

Computational analysis and in vitro evaluation of TMF 104, for its antioxidant, antimicrobial, and anticancer efficacies

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

IF2.7

2022-04-111

PRE

Glucose and oleic acid mediate cellular alterations in GLP-1-induced insulin-positive differentiating UCBMSCs

JOURNAL OF FOOD BIOCHEMISTRY

IF4.2

2022-03-040

PRE

High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2021-11-026

PREAI

FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling

PHARMACOLOGICAL REPORTS

IF3.8

2021-09-018

PRE

Cassia auriculata leaf extract ameliorates diabetic nephropathy by attenuating autophagic necroptosis via RIP-1/RIP-3-p-p38MAPK signaling

JOURNAL OF FOOD BIOCHEMISTRY

IF4.2

2021-06-0210

OAAI

Thymoquinone inhibits IL-7-induced tumor progression and metastatic invasion in prostate cancer cells by attenuating matrix metalloproteinase activity and Akt/NF-κB signaling

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

IF2.7

2020-11-1121

PREAI

Thymoquinone (Tq) protects necroptosis induced by autophagy/mitophagy-dependent oxidative stress in human bronchial epithelial cells exposed to cigarette smoke extract (CSE)

JOURNAL OF FOOD BIOCHEMISTRY

IF4.2

2020-07-0713

OAAI

Indirubin-3-monoxime and thymoquinone exhibit synergistic efficacy as therapeutic combination in in-vitro and in-vivo models of Lung cancer

ARCHIVES OF PHARMACAL RESEARCH

IF7.5

2020-06-2518

PREAI

Thymoquinone attenuates IgE-mediated allergic response via pi3k-Akt-NFκB pathway and upregulation of the Nrf2-HO1 axis

JOURNAL OF FOOD BIOCHEMISTRY

IF4.2

2020-03-2412

OAAI

FCX-146, a potent allosteric inhibitor of Akt kinase in cancer cells: Lead optimization of the second-generation arylidene indanone scaffold

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

IF2.7

2020-02-2416

PREAI

Thymoquinone attenuates oxidative stress of kidney mitochondria and exerts nephroprotective effects in oxonic acid-induced hyperuricemia rats

百里香醌减轻氧酸诱导的高尿酸血症大鼠肾脏线粒体氧化应激并发挥肾保护作用

BIOFACTORS

IF5

2019-11-2328

PREAI

Rational combinations of indirubin and arylidene derivatives exhibit synergism in human non-small cell lung carcinoma cells

JOURNAL OF FOOD BIOCHEMISTRY

IF4.2

2019-04-2414

OAAI

Thymoquinone attenuates phosphorylation of AKT to inhibit kidney cancer cell proliferation

JOURNAL OF FOOD BIOCHEMISTRY

IF4.2

2019-01-2933

OAAI

Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+]i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro

CELLS

IF5.2

2018-12-0626

OAAI

Anti-cancer effect of Cassia auriculata leaf extract in vitro through cell cycle arrest and induction of apoptosis in human breast and larynx cancer cell lines

CELL BIOLOGY INTERNATIONAL

IF3.1

2013-01-0255

PREAI

Prasanna Rajagopalan

个人简介

教育背景

工作经历

荣誉奖项

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