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P

Peter Hokland

Aarhus University
H指数:46
被引数:9,396

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工作经历

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荣誉奖项

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Dual intron-targeted CRISPR-Cas9-mediated disruption of the AML RUNX1-RUNX1T1 fusion gene effectively inhibits proliferation and decreases tumor volume in vitro and in vivo

AML RUNX1-RUNX1T1融合基因的双内含子靶向CRISPR-Cas9-mediated破坏有效抑制体外和体内肿瘤增殖并减小肿瘤体积

LEUKEMIA
IF13.4
2023-07-188
OAAI
Neldeborg, Signe; Soerensen, Johannes Frasez; Moller, Charlotte Thornild; Bill, Marie; Gao, Zongliang; Bak, Rasmus O.; Holm, Kasper; Sorensen, Boe; Nyegaard, Mette; Luo, Yonglun; Hokland, Peter; Stougaard, Magnus; Ludvigsen, Maja; Holm, Christian Kanstrup
Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions
BLOOD CANCER DISCOVERY
IF11.5
2020-07-0131
OA
Silvestri, Giovannino; Trotta, Rossana; Stramucci, Lorenzo; Ellis, Justin J.; Harb, Jason G.; Neviani, Paolo; Wang, Shuzhen; Eisfeld, Ann-Kathrin; Walker, Christopher J.; Zhang, Bin; Srutova, Klara; Gambacorti-Passerini, Carlo; Pineda, Gabriel; Jamieson, Catriona H. M.; Stagno, Fabio; Vigneri, Paolo; Nteliopoulos, Georgios; May, Philippa C.; Reid, Alistair G.; Garzon, Ramiro; Roy, Denis-Claude; Moutuou, Moutuaata M.; Guimond, Martin; Hokland, Peter; Deininger, Michael W.; Fitzgerald, Garrett; Harman, Christopher; Dazzi, Francesco; Milojkovic, Dragana; Apperley, Jane F.; Marcucci, Guido; Qi, Jianfei; Polakova, Katerina Machova; Zou, Ying; Fan, Xiaoxuan; Baer, Maria R.; Calabretta, Bruno; Perrotti, Danilo
High-Throughput Sequencing-Based Investigation of Viruses in Human Cancers by Multienrichment Approach

通过多富集方法对人类癌症中的病毒进行基于高通量测序的研究

JOURNAL OF INFECTIOUS DISEASES
IF4.5
2019-06-2811
OAAI
Mollerup, Sarah; Asplund, Maria; Friis-Nielsen, Jens; Kjartansdottir, Kristin Ros; Fridholm, Helena; Hansen, Thomas Arn; Herrera, Jose Alejandro Romero; Barnes, Christopher James; Jensen, Randi Holm; Richter, Stine Raith; Nielsen, Ida Broman; Pietroni, Carlotta; Alquezar-Planas, David E.; Rey-Iglesia, Alba; Olsen, Pernille V. S.; Rajpert-De Meyts, Ewa; Groth-Pedersen, Line; von Buchwald, Christian; Jensen, David H.; Gniadecki, Robert; Hogdall, Estrid; Langhoff, Jill Levin; Pete, Imre; Vereczkey, Ildiko; Baranyai, Zsolt; Dybkaer, Karen; Johnsen, Hans Erik; Steiniche, Torben; Hokland, Peter; Rosenberg, Jacob; Baandrup, Ulrik; Sicheritz-Ponten, Thomas; Willerslev, Eske; Brunak, Soren; Lund, Ole; Mourier, Tobias; Vinner, Lasse; Izarzugaza, Jose M. G.; Nielsen, Lars Peter; Hansen, Anders Johannes
The tumor suppressor activity of miR-300 is detrimental for leukemia development but required for leukemia stem cell maintenance
CANCER RESEARCH
IF16.6
2018-07-010
PRE
Silvestri, Giovannino; Stramucci, Lorenzo; Ellis, Justin; Harb, Jason; Neviani, Paolo; Zhang, Bin; Srutova, Klara; Pineda, Gabriel; Jamieson, Catriona; Calabretta, Bruno; Stagno, Fabio; Vigneri, Paolo; Nteliopoulos, Georgios; May, Philippa; Reid, Alistar; Garzon, Ramiro; Roy, Denis-Claude; Guimond, Martin; Hokland, Peter; Deininger, Michael; Fitzgerald, Garrett; Harman, Chris; Dazzi, Francesco; Milojkovic, Dragana; Apperley, Jane; Marcucci, Guido; Qi, Jianfei; Machova-Polakova, Katerina; Fan, Xiaoxuan; Baer, Maria; Trotta, Rossana; Perrotti, Danilo
Role of the MSC-derived exosomal and endogenous JAK2-SET/PP2A-β-catenin-modulator miR-300 in leukemic stem/progenitor proliferation and survival in CML
CANCER RESEARCH
IF16.6
2016-07-150
PRE
Trotta, Rossana; Silvestri, Giovannino; Stramucci, Lorenzo; Ellis, Justin J.; Yu, Justine; Harb, Jason J.; Neviani, Paolo; Marcucci, Guido; Srutova, Klara; Machova, Polakova K.; Roy, Denis-Claude; Hokland, Peter; Deininger, Michael; Bhatia, Ravi; Gambacorti-Passerini, Carlo; Milojkovic, Dragana; Reid, Alistair; Apperley, Jane; Livak, Ferenc; Qi, Jianfei; Baer, Maria R.; Perrotti, Danilo
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2013-09-03191
OA
Neviani, Paolo; Harb, Jason G.; Oaks, Joshua J.; Santhanam, Ramasamy; Walker, Christopher J.; Ellis, Justin J.; Ferenchak, Gregory; Dorrance, Adrienne M.; Paisie, Carolyn A.; Eiring, Anna M.; Ma, Yihui; Mao, Hsiaoyin C.; Zhang, Bin; Wunderlich, Mark; May, Philippa C.; Sun, Chaode; Saddoughi, Sahar A.; Bielawski, Jacek; Blum, William; Klisovic, Rebecca B.; Solt, Janelle A.; Byrd, John C.; Volinia, Stefano; Cortes, Jorge; Huettner, Claudia S.; Koschmieder, Steffen; Holyoake, Tessa L.; Devine, Steven; Caligiuri, Michael A.; Croce, Carlo M.; Garzon, Ramiro; Ogretmen, Besim; Arlinghaus, Ralph B.; Chen, Ching-Shih; Bittman, Robert; Hokland, Peter; Roy, Denis-Claude; Milojkovic, Dragana; Apperley, Jane; Goldman, John M.; Reid, Alistair; Mulloy, James C.; Bhatia, Ravi; Marcucci, Guido; Perrotti, Danilo
BCR-ABL1 kinase activity but not its expression is dispensable for Ph plus quiescent stem cell survival which depends on the PP2A-controlled Jak2 activation and is sensitive to FTY720 treatment
CANCER RESEARCH
IF16.6
2011-04-010
PRE
Neviani, Paolo; Harb, Jason; Oaks, Joshua; Walker, Christopher; Santhanam, Ramasamy; Paisie, Carolyn; Eiring, Anna; Zhang, Bin; Perazzona, Bastianella; Ma, Y.; Mao, Charlene; Marcucci, Guido; Holyoake, Tessa; Volinia, Stefano; Cortes, Jorge; Caligiuri, Michael; Huettner, Claudia; Bittman, Robert; Chen, Ching-Shih; Arlinghaus, Ralph; Hokland, Peter; Roy, Denis-Claude; Bhatia, Ravi; Perrotti, Danilo
Suppression of RISC-independent decoy and RISC-mediated RNA-pairing activities of microRNA-328 is required for maturation-arrest and enhanced survival of blast crisis CML progenitors
CANCER RESEARCH
IF16.6
2010-04-010
PRE
Eiring, Anna M.; Harb, Jason; Neviani, Paolo; Oaks, Joshua J.; Liu, Shujun; Spizzo, Riccardo; Schwind, Sebastian; Santhanam, Ramasamy; Hickey, Christopher; Becker, Heiko; Chandler, Jason C.; Andino, Raul; Cortes, Jorge; Hokland, Peter; Huettner, Claudia S.; Bhatia, Ravi; Roy, Denis C.; Liebhaber, Stephen; Caligiuri, Michael A.; Marcucci, Guido; Garzon, Ramiro; Croce, Carlo M.; Calin, George A.; Perrotti, Danilo

研究方向

暂未获取到该数据
G
Guido Marcucci
H 指数:118论文数:1,187被引数:5.3万
D
Danilo Perrotti
H 指数:62论文数:297被引数:1.5万
P
Paolo Neviani
H 指数:31论文数:159被引数:5,400
D
Denis‐Claude Roy
H 指数:54论文数:390被引数:1.3万
J
Jason G. Harb
H 指数:16论文数:91被引数:1,919
N
Niels Pallisgaard
H 指数:40论文数:246被引数:7,708
A
Anni Aggerholm
H 指数:19论文数:65被引数:1,652
C
Claudia S. Huettner
H 指数:27论文数:84被引数:5,038
J
Justin J. Ellis
H 指数:5论文数:37被引数:442
C
Charlotte Guldborg Nyvold
H 指数:22论文数:144被引数:1,525