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M

Matthew Freeman

university of oxford

59H指数
251论文数
1.3W被引数
收录论文 80
发表时间
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The cytoplasmic domain of the pseudoprotease iRhom2 mediates distinct signaling mechanisms to control activation of the cell surface protease ADAM17伪蛋白酶iRhom2的胞质结构域介导不同的信号机制以调控细胞表面蛋白酶ADAM17的活化。
errJournal of Biological Chemistry
IF3.9
err2025-08-28
err0
errOAAI
errFangfang Lu; Marjorie Fournier; Matthew Freeman
err分享
err收藏
Eta-secretase-like processing of the amyloid precursor protein (APP) by the rhomboid protease RHBDL4
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-08-01
err1
errOAAI
errPenalva, Ylauna Christine Megane; Paschkowsky, Sandra; Recinto, Sherilyn Junelle; Duchesne, Anthony; Hammond, Thomas; Spiegler, Pascal; Jansen, Gregor; Levet, Clemence; Charron, Francois; Freeman, Matthew; Mckinney, R. Anne; Trempe, Jean-Francois; Munter, Lisa Marie
err分享
err收藏
Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals
errMOLECULAR CELL
IF16.6
err2024-06-01
err0
errOAAI
errLu, Fangfang; Zhao, Hongtu; Dai, Yaxin; Wang, Yingdi; Lee, Chia-Hsueh; Freeman, Matthew
err分享
err收藏
Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway
errMOLECULAR CELL
IF16.6
err2024-01-01
err2
errOAAI
errDulloo, Iqbal; Tellier, Michael; Levet, Clemence; Chikh, Anissa; Zhang, Boyan; Blaydon, Diana C.; Webb, Catherine M.; Kelsell, David P.; Freeman, Matthew
err分享
err收藏
The Forest of Biologists-for biologists, for biology
errDISEASE MODELS & MECHANISMS
IF3.3
err2023-03-13
err0
errOAAI
errMoulton, O. Claire; Freeman, Matthew
err分享
err收藏
The Forest of Biologists-for biologists, for biology
errDEVELOPMENT
IF3.6
err2023-03-13
err3
errOAAI
errMoulton, O. Claire; Freeman, Matthew
err分享
err收藏
The Forest of Biologists-for biologists, for biology
errJOURNAL OF CELL SCIENCE
IF3.6
err2023-03-13
err0
errOAAI
errMoulton, O. Claire; Freeman, Matthew
err分享
err收藏
Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-03
err27
errOAAI
errTang, Jingjing; Frey, Jeremy M.; Wilson, Carole L.; Moncada-Pazos, Angela; Levet, Clemence; Freeman, Matthew; Rosenfeld, Michael E.; Stanley, E. Richard; Raines, Elaine W.; Bornfeldt, Karin E.
err分享
err收藏
iRhom2 regulates ERBB signalling to promote KRAS-driven tumour growth of lung cancer cells
errJOURNAL OF CELL SCIENCE
IF3.6
err2022-09-08
err9
errOAAI
errSieber, Boris; Lu, Fangfang; Stribbling, Stephen M.; Grieve, Adam G.; Ryan, Anderson J.; Freeman, Matthew
err分享
err收藏
The mammalian rhomboid protein RHBDL4 protects against endoplasmic reticulum stress by regulating the morphology and distribution of ER sheets
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-06-01
err5
errOAAI
errLastun, Viorica L.; Levet, Clemence; Freeman, Matthew
err分享
err收藏
iRhom pseudoproteases regulate ER stress-induced cell death through IP3 receptors and BCL-2
errNATURE COMMUNICATIONS
IF15.7
err2022-03-10
err14
errOAAI
errDulloo, Iqbal; Atakpa-Adaji, Peace; Yeh, Yi-Chun; Levet, Clemence; Muliyil, Sonia; Lu, Fangfang; Taylor, Colin W.; Freeman, Matthew
err分享
err收藏
Conformational surveillance of Orai1 by a rhomboid intramembrane protease prevents inappropriate CRAC channel activation
errMOLECULAR CELL
IF16.6
err2021-12-01
err5
errOAAI
errGrieve, Adam G.; Yeh, Yi-Chun; Chang, Yu-Fen; Huang, Hsin-Yi; Zarcone, Lucrezia; Breuning, Johannes; Johnson, Nicholas; Strisovsky, Kvido; Brown, Marion H.; Parekh, Anant B.; Freeman, Matthew
err分享
err收藏
Rhomboid Proteins in Cell Signaling
errFASEB JOURNAL
IF4.2
err2021-05-14
err0
PREAI
errFreeman, Matthew; Grieve, Adam
err分享
err收藏
The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2021-05-05
err12
errOAAI
errDusterhoft, Stefan; Kahveci-Tuerkoez, Selcan; Wozniak, Justyna; Seifert, Anke; Kasparek, Petr; Ohm, Henrike; Liu, Shixin; Kopkanova, Jana; Lokau, Juliane; Garbers, Christoph; Preisinger, Christian; Sedlacek, Radislav; Freeman, Matthew; Ludwig, Andreas
err分享
err收藏
ADAM17-triggered TNF signalling protects the ageing Drosophila retina from lipid droplet-mediated degeneration
errEMBO JOURNAL
IF8.3
err2020-07-26
err27
errOAAI
errMuliyil, Sonia; Levet, Clemence; Dusterhoft, Stefan; Dulloo, Iqbal; Cowley, Sally A.; Freeman, Matthew
err分享
err收藏
Bacterial rhomboid proteases mediate quality control of orphan membrane proteins细菌菱形蛋白酶介导孤儿膜蛋白的质量控制
errEMBO JOURNAL
IF8.3
err2020-04-27
err20
errOAAI
errLiu, Guangyu; Beaton, Stephen E.; Grieve, Adam G.; Evans, Rhiannon; Rogers, Miranda; Strisovsky, Kvido; Armstrong, Fraser A.; Freeman, Matthew; Exley, Rachel M.; Tang, Christoph M.
err分享
err收藏
Rhomboid Proteins in Cell Signaling
errFASEB JOURNAL
IF4.2
err2020-04-15
err0
errOAAI
errFreeman, Matthew
err分享
err收藏
A genome-wide association study in mice reveals a role for Rhbdf2 in skeletal homeostasis
errSCIENTIFIC REPORTS
IF3.9
err2020-02-24
err10
errOAAI
errLevy, Roei; Levet, Clemence; Cohen, Keren; Freeman, Matthew; Mott, Richard; Iraqi, Fuad; Gabet, Yankel
err分享
err收藏
Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2019-07-01
err11
errOAAI
errIkeda, Kyojiro N.; Freeman, Matthew
err分享
err收藏
FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex
errELIFE
IF0
err2018-06-13
err55
errOAAI
errKunzel, Ulrike; Grieve, Adam Graham; Meng, Yao; Sieber, Boris; Cowley, Sally A.; Freeman, Matthew
err分享
err收藏

研究方向

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合作学者
合作期刊
J
J. B. Gurdon
H 指数: 96 · 论文数: 380
F
Fräser A. Armstrong
H 指数: 93 · 论文数: 501
E
E. Richard Stanley
H 指数: 89 · 论文数: 276
J
James Briscoe
H 指数: 83 · 论文数: 427
E
Elaine W. Raines
H 指数: 80 · 论文数: 218
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