Long‐Cheng Li - Publications, H-index & Citations

Long‐Cheng Li

ractigen therapeutics

37H指数

120论文数

5.9K被引数

收录论文 44

发表时间

Oligonucleotide–siRNA conjugate for SOD1 amyotrophic lateral sclerosis: a phase 1 trial 寡核苷酸–siRNA缀合物用于SOD1肌萎缩侧索硬化症：一项1期临床试验

Nature Medicine

IF50

2026-07-15

OAAI

Weiqi Chen; Lingling Jiang; Chunling Duan; Moorim Kang; Jinyi Ye; Ling Wang; Yuesong Pan; Hui Qu; Xiaoling Liao; Xuejiao Zhou; Yichen Li; Zubao Gan; Junnan Chen; Ian Schacht; Robert F. Place; Long-Cheng Li; Yilong Wang

SCAD: A Modular Platform for Efficient Delivery of Duplex RNA to the CNS and Beyond SCAD：一种用于高效递送双链RNA至中枢神经系统及更远区域的模块化平台

Molecular Therapy Nucleic Acids

IF6.1

2025-10-30

OAAI

Moorim Kang; Wei-Hsiang Lin; Yichen Li; Feifei Xu; Xiaojie Zhou; Chunyan Si; Jianxiu Dai; Jichao He; Ian Schacht; Zubao Gan; Vera Huang; Long-Cheng Li

Intrathecal administration of a novel siRNA modality extends survival and improves motor function in the SOD1G93A ALS mouse model

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2024-03-01

OAAI

Duan, Chunling; Kang, Moorim; Pan, Xiaojie; Gan, Zubao; Huang, Vera; Li, Guanlin; Place, Robert F.; Li, Long-Cheng

Small activating RNA activation of ATOH1 promotes regeneration of human inner ear hair cells

BIOENGINEERED

IF4.2

2022-03-04

OAAI

Zhang, Yong-Li; Kang, Moorim; Wu, Jian-Cheng; Xie, Meng-Yao; Xue, Ruo-Yan; Tang, Qi; Yang, Hua; Li, Long-Cheng

Small activating RNA induced expression of VHL gene in renal cell carcinoma

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2018-04-01

PREAI

Kang, Moo Rim; Park, Ki Hwan; Lee, Chang Woo; Lee, Myeong Youl; Han, Sang-Bae; Li, Long-Cheng; Kang, Jong Soon

saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription

CELL RESEARCH

IF25.9

2016-02-23

105

OAAI

Portnoy, Victoria; Lin, Szu Hua Sharon; Li, Kathy H.; Burlingame, Alma; Hu, Zheng-Hui; Li, Hao; Li, Long-Cheng

RNAa in action: From the exception to the norm

RNA BIOLOGY

IF3.4

2015-01-20

OAAI

Guo, Dan; Barry, Liam; Lin, Sharon Szu Hua; Huang, Vera; Li, Long-Cheng

RETRACTED: Up-regulation of p21WAF1/CIP1 by miRNAs and its implications in bladder cancer cells

FEBS LETTERS

IF3

2014-11-11

OAAI

Wang, Chenghe; Chen, Zhong; Ge, Qiangqiang; Hu, Junhui; Li, Fan; Hu, Jia; Xu, Hua; Ye, Zhangqun; Li, Long-Cheng

miRNA goes nuclear

RNA BIOLOGY

IF3.4

2014-11-05

OAAI

Huang, Vera; Li, Long-Cheng

The multifaceted small RNAs 多面小rna

RNA BIOLOGY

IF3.4

2014-10-27

PREAI

Li, Long-Cheng

Demystifying the nuclear function of Argonaute proteins

RNA BIOLOGY

IF3.4

2014-01-02

OAAI

Huang, Vera; Li, Long-Cheng

saRNA Guided iNOS Up-Regulation Improves Erectile Function of Diabetic Rats

JOURNAL OF UROLOGY

IF6.8

2013-08-01

PREAI

Wang, Tao; Li, Mingchao; Yuan, Huixin; Zhan, Yin; Xu, Hua; Wang, Shaogang; Yang, Weiming; Liu, Jihong; Ye, Zhangqun; Li, Long-Cheng

Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth

CANCER RESEARCH

IF16.6

2012-09-30

OAAI

Kang, Moo Rim; Yang, Glen; Place, Robert F.; Charisse, Klaus; Epstein-Barash, Hila; Manoharan, Muthiah; Li, Long-Cheng

Intravesical delivery of lipid nanoparticle formulated p21(Waf1/Cip1) activating dsRNA induces tumor regression and enhances animal survival in a orthotopic bladder cancer model

CANCER RESEARCH

IF16.6

2012-04-01

PREAI

Kang, MooRim; Yang, Glen; Charisse, Klaus; Epstein-Barash, Hila; Manoharan, Muthiah; Li, Long-Cheng

Formulation of Small Activating RNA Into Lipidoid Nanoparticles Inhibits Xenograft Prostate Tumor Growth by Inducing p21 Expression

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2012-01-01

OAAI

Place, Robert F.; Wang, Ji; Noonan, Emily J.; Meyers, Rachel; Manoharan, Muthiah; Charisse, Klaus; Duncan, Rick; Huang, Vera; Wang, Xiaoling; Li, Long-Cheng

Transient focal ischemia induces extensive temporal changes in rat cerebral MicroRNAome

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2009-01-14

459

OAAI

Dharap, Ashuthosh; Bowen, Kellie; Place, Robert; Li, Long-Cheng; Vemuganti, Raghu

Antitumor effect of dsRNA-induced p21WAF1/CIP1 gene activation in human bladder cancer cells

MOLECULAR CANCER THERAPEUTICS

IF5.5

2008-03-17

101

OAAI

Chen, Zhong; Place, Robert F.; Jia, Zhe-Jun; Pookot, Deepa; Dahiya, Rajvir; Li, Long-Cheng

MicroRNA-373 induces expression of genes with complementary promoter sequences

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2008-02-05

1.1K

OAAI

Place, Robert F.; Li, Long-Cheng; Pookot, Deepa; Noonan, Emily J.; Dahiya, Rajvir

Chromatin changes on the GSTP1 promoter associated with its inactivation in prostate cancer GSTP1启动子上的染色质变化与其在前列腺癌中的失活相关

MOLECULAR CARCINOGENESIS

IF3.2

2007-04-05

OAAI

Okino, Steven T.; Pookot, Deepa; Majid, Shahana; Zhao, Hong; Li, Long-Cheng; Place, Robert F.; Dahiya, Rajvir

Epigenetic modifications of rassf1A gene through chromatin remodeling in prostate cancer

JOURNAL OF UROLOGY

IF6.8

2007-04-01

OAAI

Kawamoto, Ken; Okino, Steven T.; Place, Robert; Urakami, Shinji; Hirata, Hiroshi; Kikuno, Nobuyuki; Kawakami, Toshifurni; Tanaka, Yuichiro; Li, Long-Cheng; Pookot, Deepa; Zhao, Hong; Chen, Zhong; Majid, Shahana; Vejdani, Kaveh; Enokida, Hideki; Nakagawa, Masayuki; Dahiya, Rajvir

研究方向