Christopher B. Burge - Publications, H-index & Citations

Christopher B. Burge

Cambridge

79H指数

288论文数

7.2W被引数

收录论文 85

发表时间

Widespread naturally variable human exons aid genetic interpretation 广泛分布的自然变异人类外显子有助于遗传学解释

Nature Communications

IF15.7

2025-12-16

OAAI

Hannah N. Jacobs; Bram L. Gorissen; Jeremy Guez; Masahiro Kanai; Kavi Gupta; Hilary K. Finucane; Konrad J. Karczewski; Christopher B. Burge

KATMAP infers splicing factor activity and regulatory targets from knockdown data KATMAP通过敲低数据推断剪接因子活性及其调控靶点

Nature Biotechnology

IF41.7

2025-11-04

OAAI

Michael P. McGurk; David C. McWatters; Christopher B. Burge

Systematic identification of disease-causing promoter and untranslated region variants in 8040 undiagnosed individuals with rare disease 系统性鉴定罕见病未诊断患者中8040例疾病致病启动子及非编码区变异

GENOME MEDICINE

IF11.2

2025-04-14

OAAI

Martin-Geary, Alexandra C.; Blakes, Alexander J. M.; Dawes, Ruebena; Findlay, Scott D.; Lord, Jenny; Dong, Shan; Walker, Susan; Talbot-Martin, Jonathan; Wieder, Nechama; D'Souza, Elston N.; Fernandes, Maria; Hilton, Sarah; Lahiri, Nayana; Campbell, Christopher; Jenkinson, Sarah; Degoede, Christian G. E. L.; Anderson, Emily R.; Candler, Toby; Firth, Helen; Burge, Christopher B.; Sanders, Stephan J.; Ellingford, Jamie; Baralle, Diana; Whiffin, Nicola

Sequence-dependent and -independent effects of intron-mediated enhancement learned from thousands of random introns 从数千个随机内含子中学习到的内含子介导增强的序列依赖和非序列依赖效应

NUCLEIC ACIDS RESEARCH

IF13.1

2025-02-24

OAAI

Kowal, Emma J. K.; Sakai, Yuta; Mcgurk, Michael P.; Pasetsky, Zoe J.; Burge, Christopher B.

Understanding species-specific and conserved RNA-protein interactions in vivo and in vitro 了解体内和体外物种特异性和保守的RNA-蛋白质相互作用

NATURE COMMUNICATIONS

IF15.7

2024-09-27

OAAI

Harris, Sarah E.; Alexis, Maria S.; Giri, Gilbert; Cavazos, Francisco F.; Hu, Yue; Murn, Jernej; Aleman, Maria M.; Burge, Christopher B.; Dominguez, Daniel

Molecular and cellular context influences SCN8A variant function

JCI INSIGHT

IF6.1

2024-05-21

OAAI

Vanoye, Carlos G.; Abramova, Tatiana V.; DeKeyser, Jean -Marc; Ghabra, Nora F.; Oudin, Madeleine J.; Burge, Christopher B.; Helbig, Ingo; Thompson, Christopher H.; George, Alfred L.

An interpretable model of pre-mRNA splicing for animal and plant genes

SCIENCE ADVANCES

IF12.5

2024-05-10

OAAI

Mccue, Kayla; Burge, Christopher B.

Regulatory features aid interpretation of 3'UTR variants

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2024-02-01

OAAI

Romo, Lindsay; Findlay, Scott D.; Burge, Christopher B.

Improved modeling of RNA-binding protein motifs in an interpretable neural model of RNA splicing RNA剪接的可解释神经模型中RNA结合蛋白基序的改进建模

GENOME BIOLOGY

IF9.4

2024-01-16

OAAI

Gupta, Kavi; Yang, Chenxi; Mccue, Kayla; Bastani, Osbert; Sharp, Phillip A.; Burge, Christopher B.; Solar-Lezama, Armando

Quantifying negative selection in human 3′ UTRs uncovers constrained targets of RNA-binding proteins

NATURE COMMUNICATIONS

IF15.7

2024-01-02

OAAI

Findlay, Scott D.; Romo, Lindsay; Burge, Christopher B.

Splicing quality control mediated by DHX15 and its G-patch activator SUGP1

CELL REPORTS

IF6.9

2023-10-01

OAAI

Feng, Qing; Krick, Keegan; Chu, Jennifer; Burge, Christopher B.

Sensory nerves enhance triple-negative breast cancer invasion and metastasis via the axon guidance molecule PlexinB3

NPJ BREAST CANCER

IF7.6

2022-11-04

OAAI

Le, Thanh T.; Payne, Samantha L.; Buckwald, Maia N.; Hayes, Lily A.; Parker, Savannah R.; Burge, Christopher B.; Oudin, Madeleine J.

RBP Image Database: A resource for the systematic characterization of the subcellular distribution properties of human RNA binding proteins

NUCLEIC ACIDS RESEARCH

IF13.1

2022-11-02

OAAI

Bouvrette, Louis Philip Benoit; Wang, Xiaofeng; Boulais, Jonathan; Kong, Jian; Syed, Easin Uddin; Blue, Steven M.; Zhan, Lijun; Olson, Sara; Stanton, Rebecca; Wei, Xintao; Yee, Brian; Van Nostrand, Eric L.; Fu, Xiang-Dong; Burge, Christopher B.; Graveley, Brenton R.; Yeo, Gene W.; Lecuyer, Eric

Widespread occurrence of hybrid internal-terminal exons in human transcriptomes

SCIENCE ADVANCES

IF12.5

2022-01-21

OAAI

Fiszbein, Ana; McGurk, Michael; Calvo-Roitberg, Ezequiel; Kim, GyeungYun; Burge, Christopher B.; Pai, Athma A.

Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS

MOLECULAR CELL

IF16.6

2021-05-01

OAAI

Jourdain, Alexis A.; Begg, Bridget E.; Mick, Eran; Shah, Hardik; Calvo, Sarah E.; Skinner, Owen S.; Sharma, Rohit; Blue, Steven M.; Yeo, Gene W.; Burge, Christopher B.; Mootha, Vamsi K.

Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2020-08-17

OAAI

Begg, Bridget E.; Jens, Marvin; Wang, Peter Y.; Minor, Christine M.; Burge, Christopher B.

Cotargeting among microRNAs in the brain

GENOME RESEARCH

IF5.5

2019-10-24

OAAI

Cherone, Jennifer M.; Jorgji, Vjola; Burge, Christopher B.

Acidification of Tumor at Stromal Boundaries Drives Transcriptome Alterations Associated with Aggressive Phenotypes 基质边界肿瘤的酸化驱动与侵袭性表型相关的转录组改变

CANCER RESEARCH

IF16.6

2019-04-15

172

OAAI

Rohani, Nazanin; Hao, Liangliang; Alexis, Maria S.; Joughin, Brian A.; Krismer, Konstantin; Moufarrej, Mira N.; Soltis, Anthony R.; Lauffenburger, Douglas A.; Yaffe, Michael B.; Burge, Christopher B.; Bhatia, Sangeeta N.; Gertler, Frank B.

Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-03-25

344

OAAI

Kroger, Cornelia; Afeyan, Alexander; Mraz, Jasmin; Eaton, Elinor Ng; Reinhardt, Ferenc; Khodor, Yevgenia L.; Thiru, Prathapan; Bierie, Brian; Ye, Xin; Burge, Christopher B.; Weinberg, Robert A.

Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

NATURE COMMUNICATIONS

IF15.7

2019-03-22

OAAI

Yang, Ei-Wen; Bahn, Jae Hoon; Hsiaol, Esther Yun-Hua; Tan, Boon Xin; Sun, Yiwei; Fu, Ting; Zhou, Bo; Van Nostrand, Eric L.; Pratt, Gabriel A.; Freese, Peter; Wei, Xintao; Quinones-Valdez, Giovanni; Urban, Alexander E.; Graveley, Brenton R.; Burge, Christopher B.; Yeo, Gene W.; Xiao, Xinshu

研究方向