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收藏分享 收藏 Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis限制内质网相关降解能力会引发对胰岛素生物合成的急性和慢性效应
Arunagiri, Anoop; Haataja, Leena; Alam, Maroof; Gleason, Noah F.; Mastroianni, Emma; Cheng, Chao-Yin; Bazzi, Sami; Knupp, Jeffrey; Metawea, Ibrahim; Hassan, Anis; Larkin, Dennis; Fang, Deyu; Tsai, Billy; Qi, Ling; Arvan, Peter 分享 收藏 分享 收藏 Permanent neonatal diabetes-causing insulin mutations have dominant negative effects on beta cell identityZhang, Yuwei; Sui, Lina; Du, Qian; Haataja, Leena; Yin, Yishu; Viola, Ryan; Xu, Shuangyi; Nielsson, Christian Ulrik; Leibel, Rudolph L.; Barbetti, Fabrizio; Arvan, Peter; Egli, Dieter 分享 收藏 Nutrient-dependent regulation of β-cell proinsulin contentXu, Xiaoxi; Arunagiri, Anoop; Alam, Maroof; Haataja, Leena; Evans, Charles R.; Zhao, Ivy; Castro-Gutierrez, Roberto; Russ, Holger A.; Demangel, Caroline; Qi, Ling; Tsai, Billy; Liu, Ming; Arvan, Peter 分享 收藏 分享 收藏 Integration of ER protein quality-control mechanisms defines ß cell function and ER architectureShrestha, Neha; Torres, Mauricio; Zhang, Jason; Lu, You; Haataja, Leena; Reinert, Rachel B.; Knupp, Jeffrey; Chen, Yu-Jie; Parlakgul, Gunes; Arruda, Ana Paula; Tsai, Billy; Arvan, Peter; Qi, Ling 分享 收藏 分享 收藏 Adaptation to chronic ER stress enforces pancreatic β-cell plasticityChen, Chien-Wen; Guan, Bo-Jhih; Alzahrani, Mohammed R.; Gao, Zhaofeng; Gao, Long; Bracey, Syrena; Wu, Jing; Mbow, Cheikh A.; Jobava, Raul; Haataja, Leena; Zalavadia, Ajay H.; Schaffer, Ashleigh E.; Lee, Hugo; LaFramboise, Thomas; Bederman, Ilya; Arvan, Peter; Mathews, Clayton E.; Gerling, Ivan C.; Kaestner, Klaus H.; Tirosh, Boaz; Engin, Feyza; Hatzoglou, Maria 分享 收藏 分享 收藏 Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes (vol 70, pg 2580, 2021)Alam, Maroof; Arunagiri, Anoop; Haataja, Leena; Torres, Mauricio; Larkin, Dennis; Kappler, John; Jin, Niyun; Arvan, Peter 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes1型糖尿病中 β 细胞激素原加工和分泌的改变Rodriguez-Calvo, Teresa; Chen, Yi-Chun; Verchere, C. Bruce; Haataja, Leena; Arvan, Peter; Leete, Pia; Richardson, Sarah J.; Morgan, Noel G.; Qian, Wei-Jun; Pugliese, Alberto; Atkinson, Mark; Evans-Molina, Carmella; Sims, Emily K. 分享 收藏 Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft sizeSui, Lina; Xin, Yurong; Du, Qian; Georgieva, Daniela; Diedenhofen, Giacomo; Haataja, Leena; Su, Qi; Zuccaro, Michael, V; Kim, Jinrang; Fu, Jiayu; Xing, Yuan; He, Yi; Baum, Danielle; Goland, Robin S.; Wang, Yong; Oberholzer, Jose; Barbetti, Fabrizio; Arvan, Peter; Kleiner, Sandra; Egli, Dieter 分享 收藏 Normal and defective pathways in biogenesis and maintenance of the insulin storage poolLiu, Ming; Huang, Yumeng; Xu, Xiaoxi; Li, Xin; Alam, Maroof; Arunagiri, Anoop; Haataja, Leena; Ding, Li; Wang, Shusen; Itkin-Ansari, Pamela; Kaufman, Randal J.; Tsai, Billy; Qi, Ling; Arvan, Peter 分享 收藏 Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutationsWang, Heting; Saint-Martin, Cecile; Xu, Jialu; Ding, Li; Wang, Ruodan; Feng, Wenli; Liu, Ming; Shu, Hua; Fan, Zhenqian; Haataja, Leena; Arvan, Peter; Bellanne-Chantelot, Christine; Cui, Jingqiu; Huang, Yumeng 分享 收藏 
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