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Alison P. Klein

Johns Hopkins School of Medicine
H指数:76
被引数:3.6万

个人简介

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Different diabetes types and pancreatic ductal adenocarcinoma: a Mendelian randomization and pathway/gene-set analysis

不同糖尿病类型和胰腺导管腺癌：一项孟德尔随机化与通路/基因集分析

JNCI: Journal of the National Cancer Institute
IF0
2025-11-090
PRE
Ting Zhang, PhD; Xing Hua, PhD; Chirayu Mohindroo, MBBS; Xiaoyu Wang, MS; Diptavo Dutta, PhD; Jia Liu, PhD; Shilpa Katta, MS; Shengchao A Li, MS; Jiahui Wang, MS; Samuel O Antwi, PhD; Alan A Arslan, MD; Laura E Beane Freeman, PhD; Paige M Bracci, PhD, MPH; Federico Canzian, PhD; Mengmeng Du, PhD; Steven Gallinger, PhD; Phyllis J Goodman, MS; Verena Katzke, PhD; Charles Kooperberg, PhD; Loic Le Marchand, MD, PhD; Rachel E Neale, PhD; Alpa V Patel, PhD; Sandra Perdomo, PhD; Xiao-Ou Shu, MD, PhD, MPH; Kala Visvanathan, MD, MHS; Stephen K Van Den Eeden, PhD; Emily White, PhD, MS; Wei Zheng, MD, PhD, MPH; Demetrius Albanes, MD; Gabriella Andreotti, PhD, MPH; William R Bamlet, PhD; Paul Brennan, PhD; Julie E Buring, PhD; Stephen J Chanock, MD; Yu Chen, PhD, MPH; Burcu Darst, PhD; Pietro Ferrari, PhD; Edward L Giovannucci, MD, PhD; Michael Goggins, MD; Christopher Haiman, PhD; Manal Hassan, MD, MPH, PhD; Elizabeth A Holly, PhD, MPH; Rayjean J Hung, PhD; Miranda R Jones, PhD, MHS; Peter Kraft, PhD; Robert C Kurtz, MD; Núria Malats, MD, PhD; Steven C Moore, PhD, MPH; Kimmie Ng, MD, MPH; Ann L Oberg, PhD; Irene Orlow, PhD, MS; Ulrike Peters, PhD, MPH; Miquel Porta, MD, MPH, PhD; Kari G Rabe, MS; Nathaniel Rothman, MD, MPH, MHS; Maria-José Sánchez, PhD; Howard D Sesso, PhD, MPH; Debra T Silverman, PhD; Melissa C Southey, PhD; Caroline Y Um, PhD, MPH, RD; James Yarmolinsky, PhD; Herbert Yu, MD, PhD; Chen Yuan, PhD; Jun Zhong, PhD; Brian M Wolpin, MD, MPH; Harvey A Risch, MD, PhD; Laufey T Amundadottir, PhD; Alison P Klein, PhD, MHS; Kai Yu, PhD; Haoyu Zhang, PhD; Rachael Z Stolzenberg-Solomon, PhD, MPH, RD
Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits

连锁不平衡评分回归识别肝细胞癌与临床相关性状之间的遗传相关性

International Journal of Cancer
IF4.7
2025-09-270
OAAI
Younghun Han; Vikram R. Shaw; Jinyoung Byun; Aaron P. Thrift; Catherine Zhu; Donghui Li; Rikita I. Hatia; Robin Kate Kelley; Sean P. Cleary; Anna S. Lok; Paige M. Bracci; Jennifer B. Permuth; Roxana Bucur; Jennifer Knox; Jian-Min Yuan; Amit G. Singal; Prasun K. Jalal; R. Mark Ghobrial; Yuko Kono; Dimpy P. Shah; Mindie H. Nguyen; Neehar D. Parikh; Richard Kim; Hui-Chen Wu; Hashem El-Serag; Ping Chang; Yun Shin Chun; Jian Gu; Chad Huff; Asif Rashid; Lu-Yu Hwang; Alison P. Klein; Saira A. Khaderi; Ahmed O. Kaseb; Kathrine A. McGlynn; Lewis R. Roberts; Manal M. Hassan; Christopher I. Amos
Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33

KLHL17基因表达中的等位基因效应构成了 chr1p36.33 位点胰腺癌的全基因组关联信号。

NATURE COMMUNICATIONS
IF15.7
2025-04-300
OA
Connelly, Katelyn E.; Hullin, Katherine; Abdolalizadeh, Ehssan; Zhong, Jun; Eiser, Daina; O'Brien, Aidan; Collins, Irene; Das, Sudipto; Duncan, Gerard; Albanes, Demetrius; Andreotti, Gabriella; Arslan, Alan A.; Beane-Freeman, Laura; Berndt, Sonja I.; Buring, Julie E.; Campa, Daniele; Canzian, Federico; Chen, Yu; Chung, Charles C.; Eliassen, A. Heather; Gaziano, J. Michael; Giovannucci, Edward L.; Goodman, Phyllis J.; Haiman, Christopher A.; Hicks, Belynda; Hutchinson, Amy; Jones, Miranda R.; Katzke, Verena; Kooperberg, Charles; Kraft, Peter; Lee, I-Min; Lemarchand, Loic; Malats, Nuria; Manning, Michelle R.; Maennistoe, Satu; Milne, Roger; Moore, Steven C.; Mucci, Lorelei; Patel, Alpa V.; Peters, Ulrike; Real, Francisco X.; Rothman, Nathaniel; Sesso, Howard D.; Setiawan, Veronica W.; Shu, Xiao-Ou; Silverman, Debra; Stampfer, Meir J.; Southey, Melissa C.; Tobias, Geoffrey S.; Truong, Therese; Um, Caroline; Visvanathan, Kala; Wentzensen, Nicolas; White, Emily; Yuan, Chen; Zheng, Wei; Wactawski-Wende, Jean; Willett, Walter C.; Stoltzenberg-Solomon, Rachael Z.; Antwi, Samuel O.; Bracci, Paige M.; Gallinger, Steven; Goggins, Michael; Hassan, Manal; Holly, Elizabeth A.; Hung, Rayjean J.; Li, Donghui; Neale, Rachel E.; Rabe, Kari G.; Risch, Harvey A.; Yu, Herbert; Chanock, Stephen J.; Stolzenberg-Solomon, Rachael Z.; Klein, Alison P.; Wolpin, Brian M.; Hoskins, Jason W.; Andresson, Thorkell; Smith, Jill P.; Amundadottir, Laufey T.
Unraveling pancreatic cancer susceptibility at 5p15.33: Functional characterization of a novel VNTR element

5 p15.33的胰腺癌易感性: 新型VNTR元件的功能表征

CANCER RESEARCH
IF16.6
2024-09-150
PRE
O'Brien, Aidan; Kong, Hyunkyung; Patel, Minal; Connelly, Katelyn E.; Xu, Mai; Collins, Irene; Zhong, Jun; Hoskins, Jason; Ho, Michelle; Papenburg, Brenen; Iles, Mark M.; Law, Matthew H.; Landi, Maria-Teresa; Stolzenber-Solomon, Rachael; Wolpin, Brian M.; Klein, Alison P.; Orr, Nick; Chanock, Stephen J.; Lindstrom, Sara; Stern, Marc-Henri; Prokunina-Olsson, Ludmila; Choi, Jieyon; Brown, Kevin M.; Amundadottir, Laufey T.
Genome-Wide Analysis to Assess if Heavy Alcohol Consumption Modifies the Association between SNPs and Pancreatic Cancer Risk
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
IF3.4
2024-06-130
PRE
Ni, Zhanmo; Kundu, Prosenjit; Mckean, David F.; Wheeler, William; Albanes, Demetrius; Andreotti, Gabriella; Antwi, Samuel O.; Arslan, Alan A.; Bamlet, William R.; Beane-Freeman, Laura E.; Berndt, Sonja I.; Bracci, Paige M.; Brennan, Paul; Buring, Julie E.; Chanock, Stephen J.; Gallinger, Steven; Gaziano, J. M.; Giles, Graham G.; Giovannucci, Edward L.; Goggins, Michael G.; Goodman, Phyllis J.; Haiman, Christopher A.; Hassan, Manal M.; Holly, Elizabeth A.; Hung, Rayjean J.; Katzke, Verena; Kooperberg, Charles; Kraft, Peter; Lemarchand, Loic; Li, Donghui; Mccullough, Marjorie L.; Milne, Roger L.; Moore, Steven C.; Neale, Rachel E.; Oberg, Ann L.; Patel, Alpa V.; Peters, Ulrike; Rabe, Kari G.; Risch, Harvey A.; Shu, Xiao-Ou; Smith-Byrne, Karl; Visvanathan, Kala; Wactawski-Wende, Jean; White, Emily; Wolpin, Brian M.; Yu, Herbert; Zeleniuch-Jacquotte, Anne; Zheng, Wei; Zhong, Jun; Amundadottir, Laufey T.; Stolzenberg-Solomon, Rachael Z.; Klein, Alison P.
A Randomized Trial of Two Remote Health Care Delivery Models on the Uptake of Genetic Testing and Impact on PatientReported Psychological Outcomes in Families With Pancreatic Cancer: The Genetic Education, Risk Assessment, and Testing (GENERATE) Study

一项关于胰腺癌家庭基因检测的吸收和对患者报告的心理结果的影响的两种远程医疗保健模式的随机试验: 遗传教育，风险评估和测试 (GENERATE) 研究

GASTROENTEROLOGY
IF25.1
2024-05-012
PRE
Rodriguez, Nicolette J.; Furniss, C. Sloane; Yurgelun, Matthew B.; Ukaegbu, Chinedu; Constantinou, Pamela E.; Fortes, Ileana; Caruso, Alyson; Schwartz, Alison N.; Stopfer, Jill E.; Underhill-Blazey, Meghan; Kenner, Barbara; Nelson, Scott H.; Okumura, Sydney; Zhou, Alicia Y.; Coffin, Tara B.; Uno, Hajime; Horiguchi, Miki; Ocean, Allyson J.; McAllister, Florencia; Lowy, Andrew M.; Klein, Alison P.; Madlensky, Lisa; Petersen, Gloria M.; Garber, Judy E.; Lippman, Scott M.; Goggins, Michael G.; Maitra, Anirban; Syngal, Sapna
Genome-wide association study identifies high-impact susceptibility loci for hepatocellular carcinoma in North America

全基因组关联研究确定北美肝细胞癌的高影响易感位点

HEPATOLOGY
IF15.8
2024-02-205
OAAI
Hassan, Manal M.; Li, Donghui; Han, Younghun; Byun, Jinyoung; Hatia, Rikita I.; Long, Erping; Choi, Jiyeon; Kelley, Robin Kate; Cleary, Sean P.; Lok, Anna S.; Bracci, Paige; Permuth, Jennifer B.; Bucur, Roxana; Yuan, Jian-Min; Singal, Amit G.; Jalal, Prasun K.; Ghobrial, R. Mark; Santella, Regina M.; Kono, Yuko; Shah, Dimpy P.; Nguyen, Mindie H.; Liu, Geoffrey; Parikh, Neehar D.; Kim, Richard; Wu, Hui-Chen; El-Serag, Hashem; Chang, Ping; Li, Yanan; Chun, Yun Shin; Lee, Sunyoung S.; Gu, Jian; Hawk, Ernest; Sun, Ryan; Huff, Chad; Rashid, Asif; Amin, Hesham M.; Beretta, Laura; Wolff, Robert A.; Antwi, Samuel O.; Patt, Yehuda; Hwang, Lu-Yu; Klein, Alison P.; Zhang, Karen; Schmidt, Mikayla A.; White, Donna L.; Goss, John A.; Khaderi, Saira A.; Marrero, Jorge A.; Cigarroa, Francisco G.; Shah, Pankil K.; Kaseb, Ahmed O.; Roberts, Lewis R.; Amos, Christopher I.
Genetic Susceptibility to Nonalcoholic Fatty Liver Disease and Risk for Pancreatic Cancer: Mendelian Randomization
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
IF3.4
2023-06-233
OA
King, Sontoria D.; Veliginti, Swathi; Brouwers, Martijn C. G. J.; Ren, Zhewen; Zheng, Wei; Setiawan, Veronica W.; Wilkens, Lynne R.; Shu, Xiao-Ou; Arslan, Alan A.; Freeman, Laura E. Beane; Bracci, Paige M.; Canzian, Federico; Du, Mengmeng; Gallinger, Steven J.; Giles, Graham G.; Goodman, Phyllis J.; Haiman, Christopher A.; Kogevinas, Manolis; Kooperberg, Charles; LeMarchand, Loic; Neale, Rachel E.; Visvanathan, Kala; White, Emily; Albanes, Demetrius; Andreotti, Gabriella; Babic, Ana; Berndt, Sonja I.; Brais, Lauren K.; Brennan, Paul; Buring, Julie E.; Rabe, Kari G.; Bamlet, William R.; Chanock, Stephen J.; Fuchs, Charles S.; Gaziano, J. Michael; Giovannucci, Edward L.; Hackert, Thilo; Hassan, Manal M.; Katzke, Verena; Kurtz, Robert C.; Lee, I. -Min; Malats, Nuria; Murphy, Neil; Oberg, Ann L.; Orlow, Irene; Porta, Miquel; Real, Francisco X.; Rothman, Nathaniel; Sesso, Howard D.; Silverman, Debra T.; Thompson Jr, Ian M.; Wactawski-Wende, Jean; Wang, Xiaoliang; Wentzensen, Nicolas; Yu, Herbert; Zeleniuch-Jacquotte, Anne; Yu, Kai; Wolpin, Brian M.; Duell, Eric J.; Li, Donghui; Hung, Rayjean J.; Perdomo, Sandra; McCullough, Marjorie L.; Freedman, Neal D.; Patel, Alpa, V; Peters, Ulrike; Riboli, Elio; Sund, Malin; Tjonneland, Anne; Zhong, Jun; Van den Eeden, Stephen K.; Kraft, Peter; Risch, Harvey A.; Amundadottir, Laufey T.; Klein, Alison P.; Stolzenberg-Solomon, Rachael Z.; Antwi, Samuel O.
Somatic loss of ATM is a late event in pancreatic tumorigenesis

ATM的体细胞丢失是胰腺肿瘤发生的晚期事件

JOURNAL OF PATHOLOGY
IF5.2
2023-06-223
OAAI
Paranal, Raymond M.; Jiang, Zhengdong; Hutchings, Danielle; Kryklyva, Valentyna; Gauthier, Christian; Fujikura, Kohei; Nanda, Neha; Huang, Bo; Skaro, Michael; Wolfgang, Christopher L.; He, Jin; Klimstra, David S.; Brand, Randall E.; Singhi, Aatur D.; DeMarzo, Angelo; Zheng, Lei; Goggins, Michael; Brosens, Lodewijk A. A.; Hruban, Ralph H.; Klein, Alison P.; Lotan, Tamara; Wood, Laura D.; Roberts, Nicholas J.
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings ;(vol 72, pg 433, 2023)
DIABETES
IF7.5
2023-04-280
OA
Mastracci, Teresa L.; Apte, Minoti; Amundadottir, Laufey T.; Alvarsson, Alexandra; Artandi, Steven; Bellin, Melena D.; Bernal-Mizrachi, Ernesto; Caicedo, Alejandro; Campbell-Thompson, Martha; Cruz-Monserrate, Zobeida; El Ouaamari, Abdelfattah; Gaulton, Kyle J.; Geisz, Andrea; Goodarzi, Mark O.; Hara, Manami; Hull-Meichle, Rebecca L.; Kleger, Alexander; Klein, Alison P.; Kopp, Janel L.; Kulkarni, Rohit N.; Muzumdar, Mandar D.; Naren, Anjaparavanda P.; Oakes, Scott A.; Olesen, Soren S.; Phelps, Edward A.; Powers, Alvin C.; Stabler, Cherie L.; Tirkes, Temel; Whitcomb, David C.; Yadav, Dhiraj; Yong, Jing; Zaghloul, Norann A.; Pandol, Stephen J.; Sander, Maike
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings
DIABETES
IF7.5
2023-03-203
PRE
Mastracci, Teresa L.; Apte, Minoti; Amundadottir, Laufey T.; Alvarsson, Alexandra; Artandi, Steven; Bellin, Melena D.; Bernal-Mizrachi, Ernesto; Caicedo, Alejandro; Campbell-Thompson, Martha; Cruz-Monserrate, Zobeida; El Ouaamari, Abdelfattah; Gaulton, Kyle J.; Geisz, Andrea; Goodarzi, Mark O.; Hara, Manami; Hull-Meichle, Rebecca L.; Kleger, Alexander; Klein, Alison P.; Kopp, Janel L.; Kulkarni, Rohit N.; Muzumdar, Mandar D.; Naren, Anjaparavanda P.; Oakes, Scott A.; Olesen, Soren S.; Phelps, Edward A.; Powers, Alvin C.; Stabler, Cherie L.; Tirkes, Temel; Whitcomb, David C.; Yadav, Dhiraj; Yong, Jing; Zaghloul, Norann A.; Pandol, Stephen J.; Sander, Maike
Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions

全基因组分析表征癌症之间的共享遗传力，并确定新的癌症易感区域

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
2023-03-177
PRE
Lindstrom, Sara; Wang, Lu; Feng, Helian; Majumdar, Arunabha; Huo, Sijia; Macdonald, James; Harrison, Tabitha; Turman, Constance; Chen, Hongjie; Mancuso, Nicholas; Bammler, Theo; Gallinger, Steve; Gruber, Stephen B.; Gunter, Marc J.; Le Marchand, Loic; Moreno, Victor; Offit, Kenneth; De Vivo, Immaculata; O'Mara, Tracy A.; Spurdle, Amanda B.; Tomlinson, Ian; Fitzgerald, Rebecca; Gharahkhani, Puya; Gockel, Ines; Jankowski, Janusz; Macgregor, Stuart; Schumacher, Johannes; Barnholtz-Sloan, Jill; Bondy, Melissa L.; Houlston, Richard S.; Jenkins, Robert B.; Melin, Beatrice; Wrensch, Margaret; Brennan, Paul; Christiani, David C.; Johansson, Mattias; Mckay, James; Aldrich, Melinda C.; Amos, Christopher, I; Landi, Maria Teresa; Tardon, Adonina; Bishop, D. Timothy; Demenais, Florence; Goldstein, Alisa M.; Iles, Mark M.; Kanetsky, Peter A.; Law, Matthew H.; Amundadottir, Laufey T.; Stolzenberg-Solomon, Rachael; Wolpin, Brian M.; Klein, Alison; Petersen, Gloria; Risch, Harvey; Chanock, Stephen J.; Purdue, Mark P.; Scelo, Ghislaine; Pharoah, Paul; Kar, Siddhartha; Hung, Rayjean J.; Pasaniuc, Bogdan; Kraft, Peter

研究方向

暂未获取到该数据
M
Michael Goggins
H 指数:132论文数:1,051被引数:6.8万
R
Ralph H. Hruban
H 指数:209论文数:1,974被引数:20.3万
G
Gloria M. Petersen
H 指数:135论文数:766被引数:9.6万
L
Laufey T. Ámundadóttir
H 指数:54论文数:415被引数:1.3万
B
Brian M. Wolpin
H 指数:88论文数:1,210被引数:3.0万
H
Harvey A. Risch
H 指数:99论文数:928被引数:4.1万
R
Rachael Z. Stolzenberg‐Solomon
H 指数:81论文数:525被引数:2.0万
P
Peter Kraft
H 指数:158论文数:1,729被引数:10.9万
D
Donghui Li
H 指数:66论文数:449被引数:1.8万
S
Stephen J. Chanock
H 指数:170论文数:2,235被引数:12.6万