Laufey T. Ámundadóttir

national institutes of health

H指数:54

被引数:1.3万

个人简介

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教育背景

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工作经历

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荣誉奖项

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3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility

基于3D染色质的变异-基因图谱在57种人类细胞类型中的研究揭示了自身免疫性疾病易感性的细胞和遗传架构

Genome Biology

IF9.4

2025-12-080

OAAI

Khanh B. Trang; Prabhat Sharma; Laura Cook; Zachary Mount; Rajan M. Thomas; Nikhil N. Kulkarni; Emylette Cruz Cabrera; Suzanna Rachimi; Matthew C. Pahl; James A. Pippin; Chun Su; Klaus H. Kaestner; Joan M. O’Brien; Yadav Wagley; Kurt D. Hankenson; Ashley Jermusyk; Jason W. Hoskins; Laufey T. Amundadottir; Mai Xu; Kevin M. Brown; Stewart A. Anderson; Wenli Yang; Paul M. Titchenell; Patrick Seale; Babette S. Zemel; Alessandra Chesi; Neil Romberg; Megan K. Levings; Struan F. A. Grant; Andrew D. Wells

Different diabetes types and pancreatic ductal adenocarcinoma: a Mendelian randomization and pathway/gene-set analysis

不同糖尿病类型和胰腺导管腺癌：一项孟德尔随机化与通路/基因集分析

JNCI: Journal of the National Cancer Institute

IF0

2025-11-090

PRE

Ting Zhang, PhD; Xing Hua, PhD; Chirayu Mohindroo, MBBS; Xiaoyu Wang, MS; Diptavo Dutta, PhD; Jia Liu, PhD; Shilpa Katta, MS; Shengchao A Li, MS; Jiahui Wang, MS; Samuel O Antwi, PhD; Alan A Arslan, MD; Laura E Beane Freeman, PhD; Paige M Bracci, PhD, MPH; Federico Canzian, PhD; Mengmeng Du, PhD; Steven Gallinger, PhD; Phyllis J Goodman, MS; Verena Katzke, PhD; Charles Kooperberg, PhD; Loic Le Marchand, MD, PhD; Rachel E Neale, PhD; Alpa V Patel, PhD; Sandra Perdomo, PhD; Xiao-Ou Shu, MD, PhD, MPH; Kala Visvanathan, MD, MHS; Stephen K Van Den Eeden, PhD; Emily White, PhD, MS; Wei Zheng, MD, PhD, MPH; Demetrius Albanes, MD; Gabriella Andreotti, PhD, MPH; William R Bamlet, PhD; Paul Brennan, PhD; Julie E Buring, PhD; Stephen J Chanock, MD; Yu Chen, PhD, MPH; Burcu Darst, PhD; Pietro Ferrari, PhD; Edward L Giovannucci, MD, PhD; Michael Goggins, MD; Christopher Haiman, PhD; Manal Hassan, MD, MPH, PhD; Elizabeth A Holly, PhD, MPH; Rayjean J Hung, PhD; Miranda R Jones, PhD, MHS; Peter Kraft, PhD; Robert C Kurtz, MD; Núria Malats, MD, PhD; Steven C Moore, PhD, MPH; Kimmie Ng, MD, MPH; Ann L Oberg, PhD; Irene Orlow, PhD, MS; Ulrike Peters, PhD, MPH; Miquel Porta, MD, MPH, PhD; Kari G Rabe, MS; Nathaniel Rothman, MD, MPH, MHS; Maria-José Sánchez, PhD; Howard D Sesso, PhD, MPH; Debra T Silverman, PhD; Melissa C Southey, PhD; Caroline Y Um, PhD, MPH, RD; James Yarmolinsky, PhD; Herbert Yu, MD, PhD; Chen Yuan, PhD; Jun Zhong, PhD; Brian M Wolpin, MD, MPH; Harvey A Risch, MD, PhD; Laufey T Amundadottir, PhD; Alison P Klein, PhD, MHS; Kai Yu, PhD; Haoyu Zhang, PhD; Rachael Z Stolzenberg-Solomon, PhD, MPH, RD

Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33

KLHL17基因表达中的等位基因效应构成了 chr1p36.33 位点胰腺癌的全基因组关联信号。

NATURE COMMUNICATIONS

IF15.7

2025-04-300

Connelly, Katelyn E.; Hullin, Katherine; Abdolalizadeh, Ehssan; Zhong, Jun; Eiser, Daina; O'Brien, Aidan; Collins, Irene; Das, Sudipto; Duncan, Gerard; Albanes, Demetrius; Andreotti, Gabriella; Arslan, Alan A.; Beane-Freeman, Laura; Berndt, Sonja I.; Buring, Julie E.; Campa, Daniele; Canzian, Federico; Chen, Yu; Chung, Charles C.; Eliassen, A. Heather; Gaziano, J. Michael; Giovannucci, Edward L.; Goodman, Phyllis J.; Haiman, Christopher A.; Hicks, Belynda; Hutchinson, Amy; Jones, Miranda R.; Katzke, Verena; Kooperberg, Charles; Kraft, Peter; Lee, I-Min; Lemarchand, Loic; Malats, Nuria; Manning, Michelle R.; Maennistoe, Satu; Milne, Roger; Moore, Steven C.; Mucci, Lorelei; Patel, Alpa V.; Peters, Ulrike; Real, Francisco X.; Rothman, Nathaniel; Sesso, Howard D.; Setiawan, Veronica W.; Shu, Xiao-Ou; Silverman, Debra; Stampfer, Meir J.; Southey, Melissa C.; Tobias, Geoffrey S.; Truong, Therese; Um, Caroline; Visvanathan, Kala; Wentzensen, Nicolas; White, Emily; Yuan, Chen; Zheng, Wei; Wactawski-Wende, Jean; Willett, Walter C.; Stoltzenberg-Solomon, Rachael Z.; Antwi, Samuel O.; Bracci, Paige M.; Gallinger, Steven; Goggins, Michael; Hassan, Manal; Holly, Elizabeth A.; Hung, Rayjean J.; Li, Donghui; Neale, Rachel E.; Rabe, Kari G.; Risch, Harvey A.; Yu, Herbert; Chanock, Stephen J.; Stolzenberg-Solomon, Rachael Z.; Klein, Alison P.; Wolpin, Brian M.; Hoskins, Jason W.; Andresson, Thorkell; Smith, Jill P.; Amundadottir, Laufey T.

A Common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice

一种与胰腺癌风险相关的常见CTRB错折叠变异体可导致小鼠内质网应激和炎症。

GUT

IF25.8

2025-04-190

PRE

3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity

ELIFE

IF0

2025-01-150

Unraveling pancreatic cancer susceptibility at 5p15.33: Functional characterization of a novel VNTR element

5 p15.33的胰腺癌易感性: 新型VNTR元件的功能表征

CANCER RESEARCH

IF16.6

2024-09-150

PRE

The functional characterization of pancreatic ductal adenocarcinoma GWAS risk variants in primary pancreatic cells - A pilot study

CANCER RESEARCH

IF16.6

2024-09-150

PRE

A novel approach to understanding pancreas cancer risk through enhancer- promoter interactions

CANCER RESEARCH

IF16.6

2024-09-150

PRE

Functional characterization of the 1p36.33 pancreatic cancer GWAS locus

CANCER RESEARCH

IF16.6

2024-09-150

PRE

High-throughput characterization of functional variants highlights heterogeneity and polygenicity underlying lung cancer susceptibility

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2024-07-014

OAAI

Genome-Wide Analysis to Assess if Heavy Alcohol Consumption Modifies the Association between SNPs and Pancreatic Cancer Risk

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

IF3.4

2024-06-130

PRE

Ni, Zhanmo; Kundu, Prosenjit; Mckean, David F.; Wheeler, William; Albanes, Demetrius; Andreotti, Gabriella; Antwi, Samuel O.; Arslan, Alan A.; Bamlet, William R.; Beane-Freeman, Laura E.; Berndt, Sonja I.; Bracci, Paige M.; Brennan, Paul; Buring, Julie E.; Chanock, Stephen J.; Gallinger, Steven; Gaziano, J. M.; Giles, Graham G.; Giovannucci, Edward L.; Goggins, Michael G.; Goodman, Phyllis J.; Haiman, Christopher A.; Hassan, Manal M.; Holly, Elizabeth A.; Hung, Rayjean J.; Katzke, Verena; Kooperberg, Charles; Kraft, Peter; Lemarchand, Loic; Li, Donghui; Mccullough, Marjorie L.; Milne, Roger L.; Moore, Steven C.; Neale, Rachel E.; Oberg, Ann L.; Patel, Alpa V.; Peters, Ulrike; Rabe, Kari G.; Risch, Harvey A.; Shu, Xiao-Ou; Smith-Byrne, Karl; Visvanathan, Kala; Wactawski-Wende, Jean; White, Emily; Wolpin, Brian M.; Yu, Herbert; Zeleniuch-Jacquotte, Anne; Zheng, Wei; Zhong, Jun; Amundadottir, Laufey T.; Stolzenberg-Solomon, Rachael Z.; Klein, Alison P.

Uncovering dark matter in cancer by identifying epigenetic drivers

TRENDS IN GENETICS

IF16.3

2024-03-010

PRE

Artificial intelligence and improved early detection for pancreatic cancer

INNOVATION

IF25.7

2023-07-014

OAAI

Genetic Susceptibility to Nonalcoholic Fatty Liver Disease and Risk for Pancreatic Cancer: Mendelian Randomization

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

IF3.4

2023-06-233

King, Sontoria D.; Veliginti, Swathi; Brouwers, Martijn C. G. J.; Ren, Zhewen; Zheng, Wei; Setiawan, Veronica W.; Wilkens, Lynne R.; Shu, Xiao-Ou; Arslan, Alan A.; Freeman, Laura E. Beane; Bracci, Paige M.; Canzian, Federico; Du, Mengmeng; Gallinger, Steven J.; Giles, Graham G.; Goodman, Phyllis J.; Haiman, Christopher A.; Kogevinas, Manolis; Kooperberg, Charles; LeMarchand, Loic; Neale, Rachel E.; Visvanathan, Kala; White, Emily; Albanes, Demetrius; Andreotti, Gabriella; Babic, Ana; Berndt, Sonja I.; Brais, Lauren K.; Brennan, Paul; Buring, Julie E.; Rabe, Kari G.; Bamlet, William R.; Chanock, Stephen J.; Fuchs, Charles S.; Gaziano, J. Michael; Giovannucci, Edward L.; Hackert, Thilo; Hassan, Manal M.; Katzke, Verena; Kurtz, Robert C.; Lee, I. -Min; Malats, Nuria; Murphy, Neil; Oberg, Ann L.; Orlow, Irene; Porta, Miquel; Real, Francisco X.; Rothman, Nathaniel; Sesso, Howard D.; Silverman, Debra T.; Thompson Jr, Ian M.; Wactawski-Wende, Jean; Wang, Xiaoliang; Wentzensen, Nicolas; Yu, Herbert; Zeleniuch-Jacquotte, Anne; Yu, Kai; Wolpin, Brian M.; Duell, Eric J.; Li, Donghui; Hung, Rayjean J.; Perdomo, Sandra; McCullough, Marjorie L.; Freedman, Neal D.; Patel, Alpa, V; Peters, Ulrike; Riboli, Elio; Sund, Malin; Tjonneland, Anne; Zhong, Jun; Van den Eeden, Stephen K.; Kraft, Peter; Risch, Harvey A.; Amundadottir, Laufey T.; Klein, Alison P.; Stolzenberg-Solomon, Rachael Z.; Antwi, Samuel O.

Relationship between ABO Blood Group Alleles and Pancreatic Cancer Is Modulated by Secretor (FUT2) Genotype, but Not Lewis Antigen (FUT3) Genotype

ABO血型等位基因与胰腺癌之间的关系受分泌者 (FUT2) 基因型的调节，而不受Lewis抗原 (FUT3) 基因型的调节

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

IF3.4

2023-06-214

Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings ;(vol 72, pg 433, 2023)

DIABETES

IF7.5

2023-04-280

Mastracci, Teresa L.; Apte, Minoti; Amundadottir, Laufey T.; Alvarsson, Alexandra; Artandi, Steven; Bellin, Melena D.; Bernal-Mizrachi, Ernesto; Caicedo, Alejandro; Campbell-Thompson, Martha; Cruz-Monserrate, Zobeida; El Ouaamari, Abdelfattah; Gaulton, Kyle J.; Geisz, Andrea; Goodarzi, Mark O.; Hara, Manami; Hull-Meichle, Rebecca L.; Kleger, Alexander; Klein, Alison P.; Kopp, Janel L.; Kulkarni, Rohit N.; Muzumdar, Mandar D.; Naren, Anjaparavanda P.; Oakes, Scott A.; Olesen, Soren S.; Phelps, Edward A.; Powers, Alvin C.; Stabler, Cherie L.; Tirkes, Temel; Whitcomb, David C.; Yadav, Dhiraj; Yong, Jing; Zaghloul, Norann A.; Pandol, Stephen J.; Sander, Maike

Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings

DIABETES

IF7.5

2023-03-203

PRE

Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions

全基因组分析表征癌症之间的共享遗传力，并确定新的癌症易感区域

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE

IF7.2

2023-03-177

PRE

Lindstrom, Sara; Wang, Lu; Feng, Helian; Majumdar, Arunabha; Huo, Sijia; Macdonald, James; Harrison, Tabitha; Turman, Constance; Chen, Hongjie; Mancuso, Nicholas; Bammler, Theo; Gallinger, Steve; Gruber, Stephen B.; Gunter, Marc J.; Le Marchand, Loic; Moreno, Victor; Offit, Kenneth; De Vivo, Immaculata; O'Mara, Tracy A.; Spurdle, Amanda B.; Tomlinson, Ian; Fitzgerald, Rebecca; Gharahkhani, Puya; Gockel, Ines; Jankowski, Janusz; Macgregor, Stuart; Schumacher, Johannes; Barnholtz-Sloan, Jill; Bondy, Melissa L.; Houlston, Richard S.; Jenkins, Robert B.; Melin, Beatrice; Wrensch, Margaret; Brennan, Paul; Christiani, David C.; Johansson, Mattias; Mckay, James; Aldrich, Melinda C.; Amos, Christopher, I; Landi, Maria Teresa; Tardon, Adonina; Bishop, D. Timothy; Demenais, Florence; Goldstein, Alisa M.; Iles, Mark M.; Kanetsky, Peter A.; Law, Matthew H.; Amundadottir, Laufey T.; Stolzenberg-Solomon, Rachael; Wolpin, Brian M.; Klein, Alison; Petersen, Gloria; Risch, Harvey; Chanock, Stephen J.; Purdue, Mark P.; Scelo, Ghislaine; Pharoah, Paul; Kar, Siddhartha; Hung, Rayjean J.; Pasaniuc, Bogdan; Kraft, Peter

The age-dependent association of risk factors with pancreatic cancer

ANNALS OF ONCOLOGY

IF65.4

2022-07-0127

OAAI

Hepcidin-regulating iron metabolism genes and pancreatic ductal adenocarcinoma: a pathway analysis of genome-wide association studies

铁调素调控铁代谢基因与胰腺导管腺癌: 全基因组关联研究的通路分析

AMERICAN JOURNAL OF CLINICAL NUTRITION

IF6.9

2021-10-0113

OAAI

Julian-Serrano, Sachelly; Yuan, Fangcheng; Wheeler, William; Benyamin, Beben; Machiela, Mitchell J.; Arslan, Alan A.; Beane-Freeman, Laura E.; Bracci, Paige M.; Duell, Eric J.; Du, Mengmeng; Gallinger, Steven; Giles, Graham G.; Goodman, Phyllis J.; Kooperberg, Charles; Le Marchand, Loic; Neale, Rachel E.; Shu, Xiao-Ou; Van den Eeden, Stephen K.; Visvanathan, Kala; Zheng, Wei; Albanes, Demetrius; Andreotti, Gabriella; Ardanaz, Eva; Babic, Ana; Berndt, Sonja, I; Brais, Lauren K.; Brennan, Paul; Bueno-de-Mesquita, Bas; Buring, Julie E.; Chanock, Stephen J.; Childs, Erica J.; Chung, Charles C.; Fabianova, Eleonora; Foretova, Lenka; Fuchs, Charles S.; Gaziano, J. Michael; Gentiluomo, Manuel; Giovannucci, Edward L.; Goggins, Michael G.; Hackert, Thilo; Hartge, Patricia; Hassan, Manal M.; Holcatova, Ivana; Holly, Elizabeth A.; Hung, Rayjean, I; Janout, Vladimir; Kurtz, Robert C.; Lee, I-Min; Malats, Nuria; McKean, David; Milne, Roger L.; Newton, Christina C.; Oberg, Ann L.; Perdomo, Sandra; Peters, Ulrike; Porta, Miquel; Rothman, Nathaniel; Schulze, Matthias B.; Sesso, Howard D.; Silverman, Debra T.; Thompson, Ian M.; Wactawski-Wende, Jean; Weiderpass, Elisabete; Wenstzensen, Nicolas; White, Emily; Wilkens, Lynne R.; Yu, Herbert; Zeleniuch-Jacquotte, Anne; Zhong, Jun; Kraft, Peter; Li, Dounghui; Campbell, Peter T.; Petersen, Gloria M.; Wolpin, Brian M.; Risch, Harvey A.; Amundadottir, Laufey T.; Klein, Alison P.; Yu, Kai; Stolzenberg-Solomon, Rachael Z.

Laufey T. Ámundadóttir

个人简介

教育背景

工作经历

荣誉奖项

研究方向