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Rethinking the rise of early-onset gastrointestinal cancers: a call to action Weinberg, Benjamin A.; Murphy, Caitlin C.; Freyer, David R.; Greathouse, K. Leigh; Blancato, Jan K.; Stoffel, Elena M.; Drewes, Julia L.; Blaes, Anne; Salsman, John M.; You, Y. Nancy; Arem, Hannah; Mukherji, Reetu; Kanth, Priyanka; Hu, Xin; Fabrizio, Anne; Hartley, Marion L.; Giannakis, Marios; Marshall, John L. 分享 收藏
Mutation burden and anti-PD-1 outcomes are not universally associated with immune cell infiltration or lymphoid activation 突变负担和抗PD-1疗效与免疫细胞浸润或淋巴样细胞激活之间并非普遍相关。 Hsiehchen, David; Elliott, Andrew; Xiu, Joanne; Seeber, Andreas; El-Deiry, Wafik; Antonarakis, Emmanuel S.; Graff, Stephanie L.; Hall, Michael J.; Borghaei, Hossein; Hoon, Dave S. B.; V. Liu, Stephen; Ma, Patrick C.; Mckay, Rana R.; Wise-Draper, Trisha; Marshall, John; Sledge, George W.; Spetzler, David; Zhu, Hao 分享 收藏
Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer Wang, Jingyuan; Xiu, Joanne; Battaglin, Francesca; Arai, Hiroyuki; Soni, Shivani; Zhang, Wu; Goldberg, Richard M.; Philip, Philip A.; Seeber, Andreas; Hwang, Jimmy J.; Shields, Anthony F.; Marshall, John L.; Astaturov, Igor; Liu, Tianshu; Lockhart, A. Craig; Korn, W. Michael; Shen, Lin; Lenz, Heinz-Josef 分享 收藏
Tumor specimen cold ischemia time impacts molecular cancer drug target discovery von der Heyde, Silvia; Raman, Nithya; Gabelia, Nina; Matias-Guiu, Xavier; Yoshino, Takayuki; Tsukada, Yuichiro; Melino, Gerry; Marshall, John L.; Wellstein, Anton; Juhl, Hartmut; Landgrebe, Jobst 分享 收藏
Consensus molecular subtyping of metastatic colorectal cancer expands biomarker-directed therapeutic benefit for patients with CMS1 and CMS2 tumors Chowdhury, Saikat; Xiu, Joanne; Ribeiro, Jennifer R.; Nicolaides, Theodore; Zhang, Jian; Korn, W. Michael; Poorman, Kelsey A.; Lenz, Heinz-Josef; Marshall, John L.; Oberley, Matthew J.; Sledge Jr, George W.; Spetzler, David; Kopetz, Scott; Shen, John Paul 分享 收藏
Predictive value of CDC37 gene expression for targeted therapy in metastatic colorectal cancer Arai, Hiroyuki; Yang, Yan; Baca, Yasmine; Millstein, Joshua; Denda, Tadamichi; Ou, Fang-Shu; Innocenti, Federico; Takeda, Hiroyuki; Kubota, Yohei; Doi, Ayako; Horie, Yoshiki; Umemoto, Kumiko; Izawa, Naoki; Wang, Jingyuan; Battaglin, Francesca; Jayachandran, Priya; Algaze, Sandra; Soni, Shivani; Zhang, Wu; Goldberg, Richard M.; Hall, Michael J.; Scott, Aaron James; Hwang, Jimmy J.; Lou, Emil; Weinberg, Benjamin A.; Marshall, John; Goel, Sanjay; Xiu, Joanne; Korn, W. Michael; Venook, Alan P.; Sunakawa, Yu; Lenz, Heinz -Josef 分享 收藏
Tissue-specific thresholds of mutation burden associated with anti-PD-1/L1 therapy benefit and prognosis in microsatellite-stable cancers Muquith, Maishara; Espinoza, Magdalena; Elliott, Andrew; Xiu, Joanne; Seeber, Andreas; El-Deiry, Wafik; Antonarakis, Emmanuel S.; Graff, Stephanie L.; Hall, Michael J.; Borghaei, Hossein; Hoon, Dave S. B.; Liu, Stephen V.; Ma, Patrick C.; McKay, Rana R.; Wise-Draper, Trisha; Marshall, John; Sledge, George W.; Spetzler, David; Zhu, Hao; Hsiehchen, David 分享 收藏
Tissue- specific thresholds and microenvironment correlates of tumor mutation burden associated with immunotherapy benefit and prognosis in microsatellite stable cancers Muquith, Maishara; Espinoza, Magdalena; Elliott, Andrew; Xiu, Joanne; Seeber, Andreas; El-Deiry, Wafik; Antonarakis, Emmanuel S.; Graff, Stephanie; Hall, Michael J.; Borghaei, Hossein; Hoon, Dave S.; Liu, Stephen V.; Ma, Patrick C.; McKay, Rana R.; Wise-Draper, Trisha; Marshall, John; Sledge, George W.; Spetzler, David; Zhu, Hao; Hsieh, David 分享 收藏
AI enabled whole exome& transcriptome liquid biopsy addressing MCED, MRD, and therapy selection on a single platform Abraham, Jim; Domenyuk, Valeriy; Borderias, Maria Perdigones; Yoshino, Takayuki; Heath, Elisabeth I.; Lou, Emil; Liu, Stephen; Marshall, John; El-Deiry, Wafik S.; Shields, Anthony; Dietrich, Martin; Nakamura, Yoshiaki; Fujisawa, Takao; Halbert, David D.; Sacchetti, Dominic; Stahl, Seth; Stark, Adam; Klimov, Sergey; Antani, Sourabh; Nabhan, Chadi; Swensen, Jeffrey; Poste, George; Oberley, Matt; Radovich, Milan; Sledge, George W.; Spetzler, David 分享 收藏
An exploratory study of financial toxicity intervention components preferred by cancer survivors Huq, Maisha; Conley, Claire; Derry-Vick, Heather; Khoudary, Amanda; Sorgen, Lia; Billini, Osairys; Gunning, Thomas; Luck, Conor; Kaushik, Shreya; Hurley, Vanessa; Marshall, John; Weinberg, Benjamin; Tesfaye, Anteneh; Ip, Andrew; Potosky, Arnold; Schwartz, Marc D. 分享 收藏
Phase 1 Study of Hypofractionated Proton Beam Radiation Therapy in Adjuvant Pancreatic Cancer (PROTON-PANC) Weinberg, Benjamin A.; Wang, Hongkun; Noel, Marcus S.; He, Aiwu R.; Marshall, John L.; Weiner, Louis M.; Fishbein, Thomas M.; Hodgins, Nicole E.; Winslow, Emily R.; Jackson, Patrick G.; Guerra, Juan F.; Aguila, Francisco; Unger, Keith R. 分享 收藏
PBRM1 mutations might render a subtype of biliary tract cancers sensitive to drugs targeting the DNA damage repair system Zimmer, Kai; Kocher, Florian; Untergasser, Gerold; Kircher, Brigitte; Amann, Arno; Baca, Yasmine; Xiu, Joanne; Korn, W. Micheal; Berger, Martin D. D.; Lenz, Heinz-Josef; Puccini, Alberto; Fontana, Elisa; Shields, Anthony F. F.; Marshall, John L. L.; Hall, Michael; El-Deiry, Wafik S. S.; Hsiehchen, David; Macarulla, Teresa; Tabernero, Josep; Pichler, Renate; Khushman, Moh'd; Manne, Upender; Lou, Emil; Wolf, Dominik; Sokolova, Viktorija; Schnaiter, Simon; Zeimet, Alain G. G.; Gulhati, Pat; Widmann, Gerlig; Seeber, Andreas 分享 收藏
Interim results of a phase II study of fluorouracil (FU), leucovorin (LV), and nanoliposomal irinotecan (nal-IRI) in previously treated advanced biliary tract cancer (NAPOLI-2) Weinberg, B.; He, A.; Tan, B.; Turk, A.; Noel, M.; Marshall, J.; Sung, M.; Wang, H.; Ferguson, C.; Swanson, N.; Pedersen, K. 分享 收藏
The current state of molecular profiling in gastrointestinal malignancies Mukherji, Reetu; Yin, Chao; Hameed, Rumaisa; Alqahtani, Ali Z.; Kulasekaran, Monika; He, Aiwu R.; Weinberg, Benjamin A.; Marshall, John L.; Hartley, Marion L.; Noel, Marcus S. 分享 收藏
Molecular profiling of signet-ring-cell carcinoma (SRCC) from the stomach and colon reveals potential new therapeutic targets Puccini, Alberto; Poorman, Kelsey; Catalano, Fabio; Seeber, Andreas; Goldberg, Richard M.; Salem, Mohamed E.; Shields, Anthony F.; Berger, Martin D.; Battaglin, Francesca; Tokunaga, Ryuma; Naseem, Madiha; Zhang, Wu; Philip, Philip A.; Marshall, John L.; Korn, W. Michael; Lenz, Heinz-Josef 分享 收藏
Association of Homologous Recombination-DNA Damage Response Gene Mutations with Immune Biomarkers in Gastroesophageal Cancers Cerniglia, Michael; Xiu, Joanne; Grothey, Axel; Pishvaian, Michael J.; Baca, Yasmine; Hwang, Jimmy J.; Marshall, John L.; VanderWalde, Ari M.; Shields, Anthony F.; Lenz, Heinz-Josef; Korn, W. Michael; Salem, Mohamed; Philip, Philip A.; Goldberg, Richard M.; Zeng, Jia; Kim, Sunnie S. 分享 收藏
Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients Puccini, Alberto; Seeber, Andreas; Xiu, Joanne; Goldberg, Richard M.; Soldato, Davide; Grothey, Axel; Shields, Anthony F.; Salem, Mohamed E.; Battaglin, Francesca; Berger, Martin D.; El-Deiry, Wafik S.; Tokunaga, Ryuma; Naseem, Madiha; Zhang, Wu; Arora, Sukeshi Patel; Khushman, Moh'd M.; Hall, Michael J.; Philip, Philip A.; Marshall, John L.; Korn, W. Michael; Lenz, Heinz-Josef 分享 收藏
Homologous Recombination Deficiency Alterations in Colorectal Cancer: Clinical, Molecular, and Prognostic Implications 结直肠癌的同源重组缺陷改变: 临床，分子和预后意义 Moretto, Roberto; Elliott, Andrew; Zhang, Jian; Arai, Hiroyuki; Germani, Marco Maria; Conca, Veronica; Xiu, Joanne; Stafford, Phillip; Oberley, Matthew; Abraham, Jim; Spetzler, David; Rossini, Daniele; Antoniotti, Carlotta; Marshall, John; Shields, Anthony; Lopes, Gilberto; Lonardi, Sara; Pietrantonio, Filippo; Tomasello, Gianluca; Passardi, Alessandro; Tamburini, Emiliano; Santini, Daniele; Aprile, Giuseppe; Masi, Gianluca; Falcone, Alfredo; Lenz, Heinz-Josef; Korn, Michael; Cremolini, Chiara 分享 收藏
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