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A FIRST-IN-HUMAN TRIAL OF INTRATHECAL CDC1 THERAPY FOR BREAST CANCER LEPTOMENINGEAL DISEASE INDUCES ADAPTIVE IMMUNITY WITH TRANSCRIPTOMIC EVIDENCE OF IMMUNE AWAKENING IN THE CSF 一项关于鞘内CDC1疗法治疗乳腺癌软脑膜疾病的首次人体临床试验，诱导了适应性免疫，并在脑脊液中观察到转录组学证据表明免疫系统被激活。 Forsyth, Peter; Gandhi, Shipra; Law, Vincent; Ahmed, Kamran; Piteo, Cecily; Evernden, Brittany; Pina, Yolanda; Smalley, Inna; Tran, Nam; Kalinski, Pawel; Czerniecki, Brian 分享 收藏
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NK receptor signaling lowers the TCR activation threshold: role in selective recognition of cancer cells, but not healthy tissues, by TAA-specific CTLs Dong, Bowen; Obermajer, Natasa; Tsuji, Takemasa; Matsuzaki, Junko; Bonura, Cindy; Sander, Cindy; Withers, Henry; Long, Mark; Chavel, Colin A.; Olejniczak, Scott H.; Minderman, Hans; Kirkwood, John M.; Edwards, Robert P.; Storkus, Walter J.; Romero, Pedro; Kalinski, Pawel 分享 收藏
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A A FIRST IN HUMAN PHASE I TRIAL OF INTRATHECAL DENDRITIC CELLS PRIMED AGAINST HER2/HER3 IN PATIENTS WITH LEPTOMENINGEAL DISEASE FROM TRIPLE-NEGATIVE OR HER2+BREAST CANCER SHOW DEVELOPMENT OF ADAPTIVE IMMUNE RESPONSES 一项首次人体I期临床试验，评估鞘内注射针对HER2/HER3的树突状细胞在来自三阴性或HER2+乳腺癌患者的软脑膜疾病患者中诱导适应性免疫反应的发展。 Forsyth, P. A.; Gandhi, S.; Law, V; Ahmed, K. A.; Piteo, C.; Evernden, B. R.; Pina, Y.; Smalley, I; Tran, N.; Kalinski, P.; Czerniecki, B. J. 分享 收藏
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Chronic rejection models for vascularized composite tissue allotransplantation 血管化复合组织异体移植的慢性排斥反应模型 Fisher, Daniel T.; Mackey, Emily; Kononov, Eugene; Bogner, Paul N.; Sharma, Umesh; Yu, Han; Cetrulo, Curtis L.; Seshadri, Mukund; Kalinski, Pawel; Skitzki, Joseph J.; Repasky, Elizabeth A.; Kim, Minhyung 分享 收藏
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Systemic chemokine-modulatory regimen combined with neoadjuvant chemotherapy in patients with triple-negative breast cancer Gandhi, Shipra; Slomba, Ronald T.; Janes, Cayla; Fitzpatrick, Victoria; Miller, Janine; Attwood, Kristopher; Ioannou, Giorgio; Ozbey, Sinem; De Souza, Igor; Roudko, Vladimir; Kumar, Prasanna; Kalathil, Suresh; Kokolus, Kathleen M.; Wang, Jianming; Gomez, Eduardo Cortes; Takabe, Kazuaki; Edge, Stephen; Young, Jessica; Cappuccino, Helen; Opyrchal, Mateusz; O'Connor, Tracey; Levine, Ellis G.; Gnjatic, Sacha; Kalinski, Pawel 分享 收藏
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Therapeutic Anti-Tumor Efficacy of DC-Based Vaccines Targeting TME-Associated Antigens Is Improved When Combined with a Chemokine-Modulating Regimen and/or Anti-PD-L1 Taylor, Jennifer L.; Kokolus, Kathleen M.; Basse, Per H.; Filderman, Jessica N.; Cosgrove, Chloe E.; Watkins, Simon C.; Gambotto, Andrea; Lowe, Devin B.; Edwards, Robert P.; Kalinski, Pawel; Storkus, Walter J. 分享 收藏
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Chemokine-modulating regimen (rintatolimod, IFN-α2b, celecoxib): New strategy to drive CD8+T- cells into triple negative breast cancer Gandhi, Shipra; Jones, Cayla; Opyrchal, Mateusz; Slomba, Ronald; Attwood, Kristopher; Wang, Jianmin; Gomez, Eduardo Cortes; O'Connor, Tracey; Levine, Ellis; Kalinski, Pawel 分享 收藏
Comprehensive immune profiling reveals factors associated with neoadjuvant chemotherapy response in triple negative breast cancer Seager, Robert; Ko, Heidi; Pabla, Sarabjot; Senosain, Maria-Fernanda; Kalinski, Pawel; Van Roey, Erik; Gao, Shuang; Strickland, Kyle; Previs, Rebecca; Nesline, Mary; Hastings, Stephanie; Zhang, Shengle; Conroy, Jeffrey; Jensen, Taylor; Eisenberg, Marcia; Caveney, Brian; Severson, Eric; Ramkissoon, Shakti; Gandhi, Shipra 分享 收藏
Immunologic Factors Associated with Differential Response to Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer Seager, Robert J.; Ko, Heidi; Pabla, Sarabjot; Senosain, Maria-Fernanda; Kalinski, Pawel; Van Roey, Erik; Gao, Shuang; Strickland, Kyle C.; Previs, Rebecca Ann; Nesline, Mary K.; Hastings, Stephanie; Zhang, Shengle; Conroy, Jeffrey M.; Jensen, Taylor J.; Eisenberg, Marcia; Caveney, Brian; Severson, Eric A.; Ramkissoon, Shakti; Gandhi, Shipra 分享 收藏
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