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Paul G. Thomas

St Jude Children's Research Hospital
H指数:81
被引数:2.5万

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Aberrant thymic architecture and enhanced interferon signaling in Down syndrome

唐氏综合征中异常胸腺结构与增强的干扰素信号通路

Nature Communications
IF15.7
2026-10-290
OAAI
Trent Hall; Andrew Schild; Lei Li; Heather Sheppard; Hannah Chasteen; Yutian Liu; Anitria Cotton; Rashid Mehmood; Felipe Segato Dezem; Jason Hodges; Matthew Lear; Bailey Fountain; Yiping Fan; Jeffrey Gossett; Guolian Kang; Gabriela Gheorghe; Jeremy Chase Crawford; Paul Thomas; Yongqiang Feng; Gang Wu; Jasmine Plummer; Umar Boston; John D. Crispino
T and B cells recognize splicing-derived neutrophil neoantigens in lupus

T和B细胞识别狼疮中剪接来源的中性粒细胞新抗原

Nature
IF48.5
2026-10-280
OAAI
Rayan Najjar; Xiaoxing Wang; Farheen Shaikh; Ning Wang; Ethan Le; Jie An; Mohammad Pourshamsi; Cecilia Mustelin; Fatemeh Moadab; Spencer Mirabile-Brightman; Leslie Montero; Karla S. Zavala; Vincent Gureghian; Gabriela Cervantes; Sadie J. Van den Bogaerde; Samir Adhikari; Mikhail V. Pogorelyy; Paul G. Thomas; Stephen P. Schoenberger; Tomas Mustelin
Infection history and TCR sequence features shape the breadth of TCR cross-reactivity

感染史和TCR序列特征塑造了TCR交叉反应的广度

Cell Reports
IF6.9
2026-10-240
OAAI
Jessica A. Gaevert; Koshlan Mayer-Blackwell; Mikhail V. Pogorelyy; Stefan A. Schattgen; Allison M. Kirk; Susu Duan; Lee-Ann Van de Velde; Aisha Hegab Souquette; Walid Awad; Deryn G. St. James; Nicholas A. Clark; Daniel Luque Duque; E. Kaitlynn Allen; Grant Lythe; Carmen Molina-Paris; Jeremy Chase Crawford; Andrew Fiore-Gartland; Philip Bradley; Anastasia A. Minervina; Paul G. Thomas
Uneven TCR chain pairing constraints govern epitope recognition

TCR链配对的非均匀约束调控表位识别

Science
IF45.8
2026-09-030
PRE
Anastasia A. Minervina; Mikhail V. Pogorelyy; Koshlan Mayer-Blackwell; Ricky Tirtakusuma; Stefan A. Schattgen; Andrew Fiore-Gartland; Aleksandra M. Walczak; Thierry Mora; Philip Bradley; Paul G. Thomas
Receptor allostery promotes context-specific Sonic Hedgehog signaling during embryonic development

受体别构调节促进胚胎发育过程中背景特异性的Sonic Hedgehog信号传导

Nature Communications
IF15.7
2026-07-240
OA
Miriam E. Dillard; Christina A. Daly; Rojalin Pradhan; Shariq S. Ansari; Samantha J. Hack; William C. Wright; Daniel P. Stewart; Mohamed A. Ghonim; Yan Zhang; Robin Canac; Ivan P. Moskowitz; Shondra M. Pruett-Miller; Jeffrey Steinberg; Yong-Dong Wang; April D. Sykes; Motomi Mori; Christopher C. Hom; Taosheng Chen; Paul G. Thomas; James P. Bridges; Stacey K. Ogden
The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome
Leukemia
IF13.4
2026-07-210
OA
Austin C. Boucher; Wojciech Rosikiewicz; Anitria Cotton; Amber L. Broadhurst; Te Ling; Rishika Vadlamudi; Melanie Bremm; Anna-Lena Schmell; Lahiri Konada; Madeline Niederkorn; Josiah D. Murray; Yichao Li; Shilpa Narina; Sarah Inglott; Anindita Roy; Philip Ancliff; Ricky Tirtakusuma; Jing Ma; Michael P. Walsh; Jeffery M. Klco; Paul G. Thomas; Yiwen Wang; Aristotelis Tsirigos; Yong Cheng; Beisi Xu; Xiaotu Ma; Soheil Meshinchi; Elvin Wagenblast; Shondra M. Pruett-Miller; Sridhar Rao; Gang Wu; Yunusa Olufadi; Guolian Kang; Zuzana Tothova; Jeffrey W. Taub; Yubin Ge; Paresh Vyas; Jan-Henning Klusmann; John D. Crispino
High-dimensional multiomics reveals perturbations to IL-6/IL-6R axis and RUNX3 in CD4+ T cells during third-trimester pregnancy

高维多组学揭示孕晚期CD4+ T细胞中IL-6/IL-6R轴和RUNX3的扰动

Clinical & Translational Immunology
IF3.8
2026-04-280
OAAI
Jennifer R Habel; Thi H O Nguyen; Natasha de Alwis; E Kaitlynn Allen; Shihan Li; Morgan J Skinner; Jennifer A Juno; Stephen J Kent; Katherine Bond; Deborah A Williamson; Martha Lappas; Natalie J Hannan; Susan Walker; Jan Schroeder; Jeremy Chase Crawford; Paul G Thomas; Katherine Kedzierska; Louise C Rowntree
BACH2 regulates T cell lineage state to enhance CAR T cell function

BACH2调节T细胞谱系状态以增强CAR T细胞功能

Nature Immunology
IF27.6
2026-01-160
PRE
Tien-Ching Chang; Amanda Heard; John Lattin; John M. Warrington; Amanda Barrett; Jack H. Landmann; Yangdon Tenzin; Vishaal Ganesh; Bryant Thompson; Sadia Afrin; Deepesh Kumar Gupta; Ju-Fang Chang; Julie Ritchey; Mehmet Emrah Selli; Yu-Sung Hsu; Haorui Song; A. J. Federico; Avery Horn; Michael P. Meers; Evan W. Weber; Thomas J. Wandless; Jeremy Chase Crawford; Paul G. Thomas; John F. DiPersio; Stephen Gottschalk; Nathan Singh
High expression of interleukin-18 receptor alpha correlates with severe respiratory viral disease and defines T cells with reduced cytotoxic signatures

白细胞介素-18受体α的高表达与严重呼吸道病毒性疾病相关，并定义了具有降低细胞毒性特征的记忆性T细胞。

Nature Communications
IF15.7
2025-11-240
OAAI
Aira F. Cabug; Jeremy Chase Crawford; Hayley A. McQuilten; Isabelle J. H. Foo; Lilith F. Allen; Deborah Gebregzabher; Robert C. Mettelman; Tanya Novak; Janet Chou; Louise C. Rowntree; Ruth R. Hagen; Abby J. Thomson; Genevieve E. Martin; Brad Gilbertson; Michael NT Souter; Fiona James; Emma Goodall; Simone Rizzetto; Tim Flerlage; Xiaoxiao Jia; Lee-Ann Van de Velde; So Young Chang; Fabio Luciani; Ryan S. Thwaites; Jason A. Trubiano; Tom C. Kotsimbos; Allen C. Cheng; Adrienne G. Randolph; Paul G. Thomas; Jianqing Xu; Zhongfang Wang; Thi H. O. Nguyen; Brendon Y. Chua; Lukasz Kedzierski; Katherine Kedzierska
A therapeutic peptide vaccine for fibrolamellar hepatocellular carcinoma: a phase 1 trial

一种纤维层状肝细胞癌的治疗性多肽疫苗：一项1期临床试验

Nature Medicine
IF50
2025-11-240
OAAI
Marina Baretti; Allison M. Kirk; Brian H. Ladle; Zeal Kamdar; Kayla J. Bendinelli; Won Jin Ho; Samir Adhikari; Nicholas A. Clark; Balaji Sundararaman; Hao Wang; Heng-Chung Kung; Jeric Hernandez; Hanfei Qi; Sarah M. Shin; Alexei Hernandez; Mari Nakazawa; Stefan A. Schattgen; Jeremy Chase Crawford; Mark Furth; Robert A. Anders; Chris Thoburn; Neeha Zaidi; Amanda L. Huff; Julie Nauroth; Elizabeth Jaffee; Mikhail V. Pogorelyy; Paul G. Thomas; Mark Yarchoan
DNAJ-PKAc induces metabolic rewiring and enhanced glutamine flux in fibrolamellar HCC

DNAJ-PKAc诱导纤维层状肝细胞癌的代谢重编程及谷氨酰胺通量增强

Journal of Hepatology
IF33
2025-11-060
PRE
Zeal Kamdar; Ethan Neumann; Kathryn Howe; Donald Long; Waqar Arif; Daniel H. Shu; Aditya Mohan; Emma Kartalia; Jeric Hernandez; Solomon Levin; Kylie Belanger; Kayla Bendinelli; Tamara Y. Lopez-Vidal; James M. Leatherman; Kabeer Munjal; Cissy Zhang; Pratik Khare; Paul G. Thomas; Daniel J. Zabransky; Won Jin Ho; Robert D. Leone; Robert A. Anders; Anne Le; Praveen Sethupathy; Chi V. Dang; Elizabeth M. Jaffee; Mark Yarchoan
Defining molecular gene profiles that underpin superior virus-specific CD8+T cell immunity in nonagenarian and centenarians
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Menon, Tejas; Kedzierski, Lukasz; Nguyen, Oanh; Rowntree, Louise; Habel, Jennifer; Li, Shihan; Foo, Isabelle Jia-Hui; Schattgen, Stefan; Aban, Malet; Peck, Heidi; Douros, Celia; Karapanagiotidis, Theo; Nicholson, Suellen; Barr, Ian; Chaurasia, Priyanka; Littler, Dene; Gras, Stephanie; Rossjohn, Jamie; Thomas, Paul Glyndwr; Crowe, Jane; Flanagan, Katie; Luciani, Fabio; Schroeder, Jan; Van De Sandt, Carolien Emma; Kedzierska, Katherine

研究方向

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Jeremy Chase Crawford
H 指数:44论文数:349被引数:8,877
P
Peter C. Doherty
H 指数:107论文数:696被引数:4.5万
K
Katherine Kedzierska
H 指数:74论文数:382被引数:2.3万
E
E. Kaitlynn Allen
H 指数:25论文数:148被引数:2,999
R
Richard J. Webby
H 指数:106论文数:769被引数:4.3万
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Pradyot Dash
H 指数:28论文数:74被引数:5,291
M
Mikhail V. Pogorelyy
H 指数:30论文数:113被引数:3,898
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Stacey Schultz‐Cherry
H 指数:66论文数:363被引数:1.5万
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Nicole L. La Gruta
H 指数:47论文数:153被引数:7,780
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Thi H. O. Nguyen
H 指数:44论文数:180被引数:1.1万