Robert C. Glen - Publications, H-index & Citations

Robert C. Glen

Imperial College London

56H指数

366论文数

2.0W被引数

收录论文 83

发表时间

Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control 微生物三甲胺对IRAK4的抑制减弱了代谢性炎症并改善了血糖控制

Nature Metabolism

IF20.8

2025-12-08

OAAI

Julien Chilloux; Francois Brial; Amandine Everard; David Smyth; Petros Andrikopoulos; Liyong Zhang; Hubert Plovier; Antonis Myridakis; Lesley Hoyles; José Maria Moreno-Navarrete; Jèssica Latorre Luque; Viviana Casagrande; Rossella Menghini; Blerina Ahmetaj-Shala; Christine Blancher; Laura Martinez-Gili; Selin Gencer; Jane F. Fearnside; Richard H. Barton; Ana Luisa Neves; Alice R. Rothwell; Christelle Gérard; Sophie Calderari; Mark J. Williamson; Julian E. Fuchs; Lata Govada; Claire L. Boulangé; Saroor Patel; James Scott; Mark Thursz; Naomi Chayen; Robert C. Glen; Nigel J. Gooderham; Jeremy K. Nicholson; Massimo Federici; José Manuel Fernández-Real; Dominique Gauguier; Peter P. Liu; Patrice D. Cani; Marc-Emmanuel Dumas

Cerebrovascular damage caused by the gut microbe/host co-metabolite p-cresol sulfate is prevented by blockade of the EGF receptor

GUT MICROBES

IF11

2024-11-24

OAAI

Shah, Sita N.; Knausenberger, Tobias B-A.; Pontifex, Matthew G.; Connell, Emily; Le Gall, Gwenaelle; Hardy, Tom A. J.; Randall, David W.; Mccafferty, Kieran; Yaqoob, Muhammad M.; Solito, Egle; Mueller, Michael; Stachulski, Andrew V.; Glen, Robert C.; Vauzour, David; Hoyles, Lesley; Mcarthur, Simon

Regulation of blood brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide

MICROBIOME

IF12.7

2021-11-27

OAAI

Hoyles, Lesley; Pontifex, Matthew G.; Rodriguez-Ramiro, Ildefonso; Anis-Alavi, M. Areeb; Jelane, Khadija S.; Snelling, Tom; Solito, Egle; Fonseca, Sonia; Carvalho, Ana L.; Carding, Simon R.; Muller, Michael; Glen, Robert C.; Vauzour, David; McArthur, Simon

IonFlow: a galaxy tool for the analysis of ionomics data sets

METABOLOMICS

IF3.3

2021-09-25

OAAI

Iacovacci, J.; Lin, W.; Griffin, J. L.; Glen, R. C.

G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic

SCIENTIFIC REPORTS

IF3.9

2021-04-22

OAAI

Ingwersen, Thies; Linnenberg, Christian; D'Acunto, Emanuela; Temori, Shabnam; Paolucci, Irene; Wasilewski, David; Mohammadi, Behnam; Kirchmair, Johannes; Glen, Robert C.; Miranda, Elena; Glatzel, Markus; Galliciotti, Giovanna

Structure-based identification of dual ligands at the A2AR and PDE10A with anti-proliferative effects in lung cancer cell-lines

JOURNAL OF CHEMINFORMATICS

IF5.7

2021-03-03

OAAI

Kalash, Leen; Winfield, Ian; Safitri, Dewi; Bermudez, Marcel; Carvalho, Sabrina; Glen, Robert; Ladds, Graham; Bender, Andreas

Extraction and Integration of Genetic Networks from Short-Profile Omic Data Sets 短剖面组学数据集遗传网络的提取与集成

METABOLITES

IF3.7

2020-10-29

OAAI

Iacovacci, Jacopo; Peluso, Alina; Ebbels, Timothy; Ralser, Markus; Glen, Robert C.

Consequences of Lipid Remodeling of Adipocyte Membranes Being Functionally Distinct from Lipid Storage in Obesity

JOURNAL OF PROTEOME RESEARCH

IF3.6

2020-07-10

OAAI

Liu, Ke-di; Acharjee, Animesh; Hinz, Christine; Liggi, Sonia; Murgia, Antonio; Denes, Julia; Gulston, Melanie K.; Wang, Xinzhu; Chu, Yajing; West, James A.; Glen, Robert C.; Roberts, Lee D.; Murray, Andrew J.; Griffin, Julian L.

Validating the validation: reanalyzing a large-scale comparison of deep learning and machine learning models for bioactivity prediction

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2020-01-20

OAAI

Robinson, Matthew C.; Glen, Robert C.; Lee, Alpha A.

A Bone Morphogenetic Protein (BMP)-derived Peptide Based on the Type I Receptor-binding Site Modifies Cell-type Dependent BMP Signalling 基于I型受体结合位点的骨形态发生蛋白 (BMP) 衍生肽可修饰细胞类型依赖性BMP信号传导

SCIENTIFIC REPORTS

IF3.9

2019-09-17

OAAI

Tong, Zhen; Guo, Jingxu; Glen, Robert C.; Morrell, Nicholas W.; Li, Wei

Colocalization Features for Classification of Tumors Using Desorption Electrospray Ionization Mass Spectrometry Imaging

ANALYTICAL CHEMISTRY

IF6.7

2019-04-23

OAAI

Inglese, Paolo; Correia, Goncalo; Pruski, Pamela; Glen, Robert C.; Takats, Zoltan

A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2019-04-01

OAAI

Yang, Peiran; Read, Cai; Kuc, Rhoda E.; Nyimanu, Duuamene; Williams, Thomas L.; Crosby, Alexi; Buonincontri, Guido; Southwood, Mark; Sawiak, Stephen J.; Glen, Robert C.; Morrell, Nicholas W.; Davenport, Anthony P.; Maguire, Janet J.

PhenoMeNal: processing and analysis of metabolomics data in the cloud

GIGASCIENCE

IF3.9

2018-12-07

OAAI

Peters, Kristian; Bradbury, James; Bergmann, Sven; Capuccini, Marco; Cascante, Marta; de Atauri, Pedro; Ebbels, Timothy M. D.; Foguet, Carles; Glen, Robert; Gonzalez-Beltran, Alejandra; Gunther, Ulrich L.; Handakas, Evangelos; Hankemeier, Thomas; Haug, Kenneth; Herman, Stephanie; Holub, Petr; Izzo, Massimiliano; Jacob, Daniel; Johnson, David; Jourdan, Fabien; Kale, Namrata; Karaman, Ibrahim; Khalili, Bita; Khonsari, Payam Emami; Kultima, Kim; Lampa, Samuel; Larsson, Anders; Ludwig, Christian; Moreno, Pablo; Neumann, Steffen; Novella, Jon Ander; O'Donovan, Claire; Pearce, Jake T. M.; Peluso, Alina; Piras, Marco Enrico; Pireddu, Luca; Reed, Michelle A. C.; Rocca-Serra, Philippe; Roger, Pierrick; Rosato, Antonio; Rueedi, Rico; Ruttkies, Christoph; Sadawi, Noureddin; Salek, Reza M.; Sansone, Susanna-Assunta; Selivanov, Vitaly; Spjuth, Ola; Schober, Daniel; Thevenot, Etienne A.; Tomasoni, Mattia; van Rijswijk, Merlijn; van Vliet, Michael; Viant, Mark R.; Weber, Ralf J. M.; Zanetti, Gianluigi; Steinbeck, Christoph

Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-09-01

OAAI

Kalash, Leen; Cresser-Brown, Joel; Habchi, Johnny; Morgan, Connor; Miller, David J.; Glen, Robert C.; Allemann, Rudolf K.; Bender, Andreas

Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier

MICROBIOME

IF12.7

2018-03-21

386

OAAI

Hoyles, Lesley; Snelling, Tom; Umlai, Umm-Kulthum; Nicholson, Jeremy K.; Carding, Simon R.; Glen, Robert C.; McArthur, Simon

Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases 神经退行性疾病关键蛋白A1R，A2AR和PDE10A多靶点配体的计算机辅助设计

JOURNAL OF CHEMINFORMATICS

IF5.7

2017-12-30

OAAI

Kalash, Leen; Val, Cristina; Azuaje, Jhonny; Loza, Maria I.; Svensson, Fredrik; Zoufir, Azedine; Mervin, Lewis; Ladds, Graham; Brea, Jose; Glen, Robert; Sotelo, Eddy; Bender, Andreas

Pharmacological targeting of apelin impairs glioblastoma growth apelin的药理学靶向损害胶质母细胞瘤的生长

BRAIN

IF11.7

2017-10-03

OAAI

Harford-Wright, Elizabeth; Andre-Gregoire, Gwennan; Jacobs, Kathryn A.; Treps, Lucas; Le Gonidec, Sophie; Leclair, Heloise M.; Gonzalez-Diest, Sara; Roux, Quentin; Guillonneau, Francois; Loussouarn, Delphine; Oliver, Lisa; Vallette, Francois M.; Foufelle, Fabienne; Valet, Philippe; Davenport, Anthony P.; Glen, Robert C.; Bidere, Nicolas; Gavard, Julie

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

CIRCULATION

IF38.6

2017-03-21

199

OAAI

Yang, Peiran; Read, Cai; Kuc, Rhoda E.; Buonincontri, Guido; Southwood, Mark; Torella, Rubben; Upton, Paul D.; Crosby, Alexi; Sawiak, Stephen J.; Carpenter, T. Adrian; Glen, Robert C.; Morrell, Nicholas W.; Maguire, Janet J.; Davenport, Anthony P.

[Pyr1]Apelin-13(1-12) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr1]Apelin-13

FRONTIERS IN NEUROSCIENCE

IF3.2

2017-02-28

OAAI

Yang, Peiran; Kuc, Rhoda E.; Brame, Aimee L.; Dyson, Alex; Singer, Mervyn; Glen, Robert C.; Cheriyan, Joseph; Wilkinson, Ian B.; Davenport, Anthony P.; Maguire, Janet J.

Deep learning and 3D-DESI imaging reveal the hidden metabolic heterogeneity of cancer

CHEMICAL SCIENCE

IF7.4

2017-01-01

124

OAAI

Inglese, Paolo; McKenzie, James S.; Mroz, Anna; Kinross, James; Veselkov, Kirill; Holmes, Elaine; Takats, Zoltan; Nicholson, Jeremy K.; Glen, Robert C.

研究方向