William C. Copeland - Publications, H-index & Citations

William C. Copeland

national institutes of health (nih) - usa

66H指数

204论文数

1.3W被引数

收录论文 94

发表时间

Mitochondrial DNA Replication and Disease: A Historical Perspective on Molecular Insights and Therapeutic Advances 线粒体DNA复制与疾病：从历史角度探讨分子见解和治疗进展

International Journal of Molecular Sciences 2025, Vol. 26, Page 10275

IF0

2025-10-22

OAAI

Shruti Somai; Chioma H. Aloh; Dillon E. King; William C. Copeland

DNA repair pathways in the mitochondria 线粒体中的DNA修复途径

DNA REPAIR

IF2.7

2025-02-01

PREAI

King, Dillon E.; Copeland, William C.

Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ

NUCLEIC ACIDS RESEARCH

IF13.1

2024-08-06

OAAI

Riccio, Amanda A.; Bouvette, Jonathan; Pedersen, Lars C.; Somai, Shruti; Dutcher, Robert C.; Borgnia, Mario J.; Copeland, William C.

Coordinated DNA polymerization by Polγ and the region of LonP1 regulated proteolysis

NUCLEIC ACIDS RESEARCH

IF13.1

2024-06-27

OAAI

Riccio, Amanda A.; Brannon, Asia J.; Krahn, Juno M.; Bouvette, Jonathan; Williams, Jason G.; Borgnia, Mario J.; Copeland, William C.

Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA

NUCLEIC ACIDS RESEARCH

IF13.1

2023-08-18

OAAI

Wojtaszek, Jessica L.; Hoff, Kirsten E.; Longley, Matthew J.; Kaur, Parminder; Andres, Sara N.; Wang, Hong; Williams, R. Scott; Copeland, William C.

Method for the structural analysis of Twinkle mitochondrial DNA helicase by cryo-EM Twinkle线粒体DNA解旋酶的冷冻电镜结构分析方法

METHODS

IF4.3

2022-09-01

OAAI

Riccio, Amanda A.; Bouvette, Jonathan; Longley, Matthew J.; Krahn, Juno M.; Borgnia, Mario J.; Copeland, William C.

Automated systematic evaluation of cryo-EM specimens with SmartScope 使用SmartScope自动系统评估cryo-em样品

ELIFE

IF0

2022-08-23

OAAI

Bouvette, Jonathan; Huang, Qinwen; Riccio, Amanda A.; Copeland, William C.; Bartesaghi, Alberto; Borgnia, Mario J.

Structural insight and characterization of human Twinkle helicase in mitochondrial disease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-08-01

OAAI

Riccio, Amanda A.; Bouvette, Jonathan; Perera, Lalith; Longley, Matthew J.; Krahn, Juno M.; Williams, Jason G.; Dutcher, Robert; Borgnia, Mario J.; Copeland, William C.

Activation of the SARS-CoV-2 NSP14 3′-5′ exoribonuclease by NSP10 and response to antiviral inhibitors

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-01-01

OAAI

Riccio, Amanda A.; Sullivan, Eric D.; Copeland, William C.

Mechanisms of SSBP1 variants in mitochondrial disease: Molecular dynamics simulations reveal stable tetramers with altered DNA binding surfaces

DNA REPAIR

IF2.7

2021-11-01

OAAI

Gustafson, Margaret A.; Perera, Lalith; Shi, Min; Copeland, William C.

Polymerase γ efficiently replicates through many natural template barriers but stalls at the HSP1 quadruplex

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-12-01

OAAI

Sullivan, Eric D.; Longley, Matthew J.; Copeland, William C.

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging

GENOME BIOLOGY

IF9.4

2020-09-17

OAAI

Lujan, Scott A.; Longley, Matthew J.; Humble, Margaret H.; Lavender, Christopher A.; Burkholder, Adam; Blakely, Emma L.; Alston, Charlotte L.; Gorman, Grainne S.; Turnbull, Doug M.; McFarland, Robert; Taylor, Robert W.; Kunkel, Thomas A.; Copeland, William C.

Consequences of compromised mitochondrial genome integrity

DNA REPAIR

IF2.7

2020-09-01

OAAI

Gustafson, Margaret A.; Sullivan, Eric D.; Copeland, William C.

Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase 人线粒体闪烁解旋酶解旋DNA的单分子水平结构动力学

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-04-01

OAAI

Kaur, Parminder; Longley, Matthew J.; Pan, Hai; Wang, Wendy; Countryman, Preston; Wang, Hong; Copeland, William C.

SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder SSBP1突变导致复杂的视神经萎缩疾病的mtDNA耗竭

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2019-11-18

OAAI

Del Dotto, Valentina; Ullah, Farid; Di Meo, Ivano; Magini, Pamela; Gusic, Mirjana; Maresca, Alessandra; Caporali, Leonardo; Palombo, Flavia; Tagliavini, Francesca; Baugh, Evan Harris; Macao, Bertil; Szilagyi, Zsolt; Peron, Camille; Gustafson, Margaret A.; Khan, Kamal; La Morgia, Chiara; Barboni, Piero; Carbonelli, Michele; Valentino, Maria Lucia; Liguori, Rocco; Shashi, Vandana; Sullivan, Jennifer; Nagaraj, Shashi; El-Dairi, Mays; Iannaccone, Alessandro; Cutcutache, Ioana; Bertini, Enrico; Carrozzo, Rosalba; Emma, Francesco; Diomedi-Camassei, Francesca; Zanna, Claudia; Armstrong, Martin; Page, Matthew; Stong, Nicholas; Boesch, Sylvia; Kopajtich, Robert; Wortmann, Saskia; Sperl, Wolfgang; Davis, Erica E.; Copeland, William C.; Seri, Marco; Falkenberg, Maria; Prokisch, Holger; Katsanis, Nicholas; Tiranti, Valeria; Pippucci, Tommaso; Carelli, Valerio

NATURE REVIEWS NEUROLOGY

IF33.1

2018-11-19

227

OAAI

Rahman, Shamima; Copeland, William C.

Single-molecule DREEM imaging reveals DNA wrapping around human mitochondrial single-stranded DNA binding protein

NUCLEIC ACIDS RESEARCH

IF13.1

2018-09-26

OAAI

Kaur, Parminder; Longley, Matthew J.; Pan, Hai; Wang, Hong; Copeland, William C.

The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein

DNA REPAIR

IF2.7

2018-05-01

OAAI

Sharma, Nidhi; Chakravarthy, Srinivas; Longley, Matthew J.; Copeland, William C.; Prakash, Aishwarya

DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria

DNA REPAIR

IF2.7

2017-12-01

OAAI

Prasad, Rajendra; Caglayan, Melike; Dai, Da-Peng; Nadalutti, Cristina A.; Zhao, Ming-Lang; Gassman, Natalie R.; Janoshazi, Agnes K.; Stefanick, Donna F.; Horton, Julie K.; Krasich, Rachel; Longley, Matthew J.; Copeland, William C.; Griffith, Jack D.; Wilson, Samuel H.

Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts

NUCLEIC ACIDS RESEARCH

IF13.1

2017-07-26

OAAI

Caglayan, Melike; Prasad, Rajendra; Krasich, Rachel; Longley, Matthew J.; Kadoda, Kei; Tsuda, Masataka; Sasanuma, Hiroyuki; Takeda, Shunichi; Tano, Keizo; Copeland, William C.; Wilson, Samuel H.

研究方向