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William C. Copeland

national institutes of health (nih) - usa

H指数:66

被引数:1.2万

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Mitochondrial DNA Replication and Disease: A Historical Perspective on Molecular Insights and Therapeutic Advances

线粒体DNA复制与疾病：从历史角度探讨分子见解和治疗进展

International Journal of Molecular Sciences 2025, Vol. 26, Page 10275

IF0

2025-10-220

OAAI

DNA repair pathways in the mitochondria

线粒体中的DNA修复途径

IF2.7

2025-02-010

PRE

Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ

NUCLEIC ACIDS RESEARCH

IF13.1

2024-08-060

OA

Coordinated DNA polymerization by Polγ and the region of LonP1 regulated proteolysis

NUCLEIC ACIDS RESEARCH

IF13.1

2024-06-270

OA

Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA

NUCLEIC ACIDS RESEARCH

IF13.1

2023-08-183

OA

Method for the structural analysis of Twinkle mitochondrial DNA helicase by cryo-EM

Twinkle线粒体DNA解旋酶的冷冻电镜结构分析方法

IF4.3

2022-09-012

OAAI

Automated systematic evaluation of cryo-EM specimens with SmartScope

使用SmartScope自动系统评估cryo-em样品

IF0

2022-08-2328

OA

Structural insight and characterization of human Twinkle helicase in mitochondrial disease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-08-019

OAAI

Activation of the SARS-CoV-2 NSP14 3′-5′ exoribonuclease by NSP10 and response to antiviral inhibitors

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-01-0122

OAAI

Mechanisms of SSBP1 variants in mitochondrial disease: Molecular dynamics simulations reveal stable tetramers with altered DNA binding surfaces

IF2.7

2021-11-018

OAAI

Polymerase γ efficiently replicates through many natural template barriers but stalls at the HSP1 quadruplex

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-12-0117

OAAI

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging

IF9.4

2020-09-1749

OAAI

Consequences of compromised mitochondrial genome integrity

IF2.7

2020-09-0135

OAAI

Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase

人线粒体闪烁解旋酶解旋DNA的单分子水平结构动力学

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-04-0114

OAAI

SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder

SSBP1突变导致复杂的视神经萎缩疾病的mtDNA耗竭

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2019-11-1864

OA

Del Dotto, Valentina; Ullah, Farid; Di Meo, Ivano; Magini, Pamela; Gusic, Mirjana; Maresca, Alessandra; Caporali, Leonardo; Palombo, Flavia; Tagliavini, Francesca; Baugh, Evan Harris; Macao, Bertil; Szilagyi, Zsolt; Peron, Camille; Gustafson, Margaret A.; Khan, Kamal; La Morgia, Chiara; Barboni, Piero; Carbonelli, Michele; Valentino, Maria Lucia; Liguori, Rocco; Shashi, Vandana; Sullivan, Jennifer; Nagaraj, Shashi; El-Dairi, Mays; Iannaccone, Alessandro; Cutcutache, Ioana; Bertini, Enrico; Carrozzo, Rosalba; Emma, Francesco; Diomedi-Camassei, Francesca; Zanna, Claudia; Armstrong, Martin; Page, Matthew; Stong, Nicholas; Boesch, Sylvia; Kopajtich, Robert; Wortmann, Saskia; Sperl, Wolfgang; Davis, Erica E.; Copeland, William C.; Seri, Marco; Falkenberg, Maria; Prokisch, Holger; Katsanis, Nicholas; Tiranti, Valeria; Pippucci, Tommaso; Carelli, Valerio

POLG-related disorders and their neurological manifestations

NATURE REVIEWS NEUROLOGY

IF33.1

2018-11-19227

OAAI

Single-molecule DREEM imaging reveals DNA wrapping around human mitochondrial single-stranded DNA binding protein

NUCLEIC ACIDS RESEARCH

IF13.1

2018-09-2627

OAAI

The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein

IF2.7

2018-05-0121

OAAI

DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria

IF2.7

2017-12-0153

OAAI

Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts

NUCLEIC ACIDS RESEARCH

IF13.1

2017-07-2619

OAAI