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Recombinant H77C gpE1/gpE2 heterodimer elicits superior HCV cross-neutralisation than H77C gpE2 alone 重组H77C gpE1/gpE2异二聚体引起的HCV交叉中和作用优于单独的H77C gpE2 Kundu, Juthika; Le, Hoa T.; Logan, Michael; Hockman, Darren; Landi, Abdolamir; Crawford, Kevin; Wininger, Mark; Johnson, Janelle; Kundu, Joydeb K.; Tiffney, E. Alana; Urbanowicz, Richard A.; Ball, Jonathan K.; Bailey, Justin R.; Bukh, Jens; Law, Mansun; Foung, Steven; Tyrrell, D. Lorne; Houghton, Michael; Law, John Lokman 分享 收藏
Small molecules targeting GRP78 mitigate anti-GRP78 autoantibody-mediated tissue factor procoagulant activity in cultured endothelial cells Chen, Jack; Lynn, Edward G.; Sharma, Hitesh; Byun, Jae H.; Kenyon, Victor A.; Sahu, Kamlesh K.; Tyrrell, D. Lorne; Houghton, Michael; Gross, Peter L.; Trigatti, Bernardo L.; Shayegan, Bobby; Austin, Richard C. 分享 收藏
Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model 丙型肝炎病毒控制的人类感染模型的挑战接种物 Liang, T. Jake; Law, John L. M.; Pietschmann, Thomas; Ray, Stuart C.; Bukh, Jens; Bull, Rowena; Chung, Raymond T.; Tyrrell, D. Lorne; Houghton, Michael; Rice, Charles M. 分享 收藏
Bovine Serum Albumin-Protected Gold Nanoclusters for Sensing of SARS-CoV-2 Antibodies and Virus Shen, Qiming; Hossain, Faisal; Fang, Changhao; Shu, Tong; Zhang, Xueji; Law, John Lok Man; Logan, Michael; Houghton, Michael; Tyrrell, D. Lorne; Joyce, Michael A.; Serpe, Michael J. 分享 收藏
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Three-Dimensional Reconstruction of the Hepatitis C Virus Envelope Glycoprotein E1E2 Heterodimer by Electron Microscopic Analysis Kanai, Tapan; Hu, Zongyi; Yang, Renbin; Wu, Weimin; Wang, Ziqiu; Ma, Christopher D.; Sanchez-Meza, Jaime; Law, Mansun; Houghton, Michael; Law, John Lokman; Logan, Michael; de Val, Natalia; Liang, T. Jake 分享 收藏
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A Fibrosis-Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis Gindin, Yevgeniy; Chung, Chuhan; Jiang, Zhaoshi; Zhou, Jing Zhu; Xu, Jun; Billin, Andrew N.; Myers, Robert P.; Goodman, Zachary; Landi, Abdolamir; Houghton, Michael; Green, Richard M.; Levy, Cynthia; Kowdley, Kris V.; Bowlus, Christopher L.; Muir, Andrew J.; Trauner, Michael 分享 收藏
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Chlorcyclizine Inhibits Viral Fusion of Hepatitis C Virus Entry by Directly Targeting HCV Envelope Glycoprotein 1 Hu, Zongyi; Rolt, Adam; Hu, Xin; Ma, Christopher D.; Le, Derek J.; Park, Seung Bum; Houghton, Michael; Southall, Noel; Anderson, D. Eric; Talley, Daniel C.; Lloyd, John R.; Marugan, Juan C.; Liang, T. Jake 分享 收藏
Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells Santer, Deanna M.; Minty, Gillian E. S.; Golec, Dominic P.; Lu, Julia; May, Julia; Namdar, Afshin; Shah, Juhi; Elahi, Shokrollah; Proud, David; Joyce, Michael; Tyrrell, D. Lorne; Houghton, Michael 分享 收藏
Effect of Different Adjuvants on the Longevity and Strength of Humoral and Cellular Immune Responses to the HCV Envelope Glycoproteins Akache, Bassel; Deschatelets, Lise; Harrison, Blair A.; Dudani, Renu; Stark, Felicity C.; Jia, Yimei; Landi, Amir; Law, John L. M.; Logan, Michael; Hockman, Darren; Kundu, Juthika; Tyrrell, D. Lorne; Krishnan, Lakshmi; Houghton, Michael; McCluskie, Michael J. 分享 收藏
A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1 重组丙型肝炎病毒基因型1a E1/E2包膜糖蛋白疫苗通过E2的N端高变区1与清道夫受体B1的相互作用，引发差异中和密切相关的2a菌株的抗体 Johnson, Janelle; Freedman, Holly; Logan, Michael; Wong, Jason Alexander Ji-Xhin; Hockman, Darren; Chen, Chao; He, Jianqi; Beard, Michael R.; Eyre, Nicholas S.; Baumert, Thomas F.; Tyrrell, D. Lorne; Law, John L. M.; Houghton, Michael 分享 收藏
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Comprehensive in vitro characterization of PD-L1 small molecule inhibitors Ganesan, Aravindhan; Ahmed, Marawan; Okoye, Isobel; Arutyunova, Elena; Babu, Dinesh; Turnbull, William L.; Kundu, Joydeb Kumar; Shields, Justin; Agopsowicz, Katharine Cheryl; Xu, Lai; Tabana, Yasser; Srivastava, Nutan; Zhang, Guangzhi; Moon, Tae Chul; Belovodskiy, Alexandr; Hena, Mostofa; Kandadai, Appan Srinivas; Hosseini, Seyedeh N. Argess; Hitt, Mary; Walker, John; Smylie, Michael; West, Frederick G.; Siraki, Arno G.; Lemieux, M. Joanne; Elahi, Shokrollah; Nieman, James A.; Tyrrell, D. Lorne; Houghton, Michael; Barakat, Khaled 分享 收藏
A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors Banda, Dominic H.; Perin, Paula M.; Brown, Richard J. P.; Todt, Daniel; Solodenko, Wladimir; Hoffmeyer, Patrick; Sahu, Kamlesh Kumar; Houghton, Michael; Meuleman, Philip; Mueller, Rolf; Kirschning, Andreas; Pietschmann, Thomas 分享 收藏
Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants Khera, Tanvi; Behrendt, Patrick; Bankwitz, Dorothea; Brown, Richard J. P.; Todt, Daniel; Doepke, Mandy; Khan, Abdul Ghafoor; Schulze, Kai; Law, John; Logan, Michael; Hockman, Darren; Wong, Jason Alexander Ji-Xhin; Dold, Leona; Gonzalez-Motos, Victor; Spengler, Ulrich; Viejo-Borbolla, Abel; Stroeh, Luisa J.; Krey, Thomas; Tarr, Alexander W.; Steinmann, Eike; Manns, Michael P.; Klein, Florian; Guzman, Carlos A.; Marcotrigiano, Joseph; Houghton, Michael; Pietschmann, Thomas 分享 收藏
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