Wenxin Xu - Publications, H-index & Citations

Wenxin Xu

Dana-Farber Cancer Institute

26H指数

301论文数

5.2K被引数

收录论文 49

发表时间

6 Antitumor Activity of 177Lu-PSMA-617 in PSMA-Positive Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): Results from a Phase 2 Trial (LASER)6 177Lu-PSMA-617在PSMA阳性转移性透明细胞肾细胞癌(ccRCC)中的抗肿瘤活性：来自一项2期试验(LASER)的结果

Oncologist

IF4.2

2026-09-02

OAAI

Praful Ravi; Wanling Xie; Shir Hazut Krauthammer; Liliana Ascione; Luke Arsenault; Liliane Kabarame; Nicole LaBrecque; Hina Shah; Stephanie Berg; Atish Choudhury; Bradley McGregor; Michael Serzan; Wenxin Xu; Srinivas Viswanathan; Xiao Wei; Toni Choueiri; Heather Jacene

Current evidence and future directions for KIM-1 as a blood-based biomarker in RCC KIM-1作为RCC中基于血液的生物标志物的当前证据和未来方向

Nature Reviews Clinical Oncology

IF82.2

2026-05-20

PREAI

Wenxin Xu; Joseph V. Bonventre; Toni K. Choueiri

A Mitochondrial Plasma Proteomic Signature Identifies Metastatic Chromophobe Renal Cell Carcinoma 线粒体血浆蛋白质组学特征可识别转移性嗜酸性肾细胞癌

Cancers

IF4.4

2026-04-03

OAAI

Clara Steiner; Tiegang Han; Steven Safi; Wafaa Bzeih; Hadi Mansour; Eddy Saad; Jessica F. Williams; Michelle S. Hirsch; Vinay K. Giri; Liliana Ascione; Yehonatan Elon; Adam P. Dicker; Yan Tang; Toni K. Choueiri; Elizabeth P. Henske; Wenxin Xu

Advanced Urologic Cancer Consensus Conference (AUC3) 2025: Expert consensus on the management of renal cell and urinary tract cancers 高级泌尿肿瘤共识会议（AUC3）2025：肾细胞癌和尿路肿瘤管理的专家共识

CA: A Cancer Journal for Clinicians

IF0

2025-12-13

OAAI

Rana R. McKay MD; Sumanta Pal MD; Wanling Xie MS; David Aggen MD, PhD; Laurence Albiges MD, PhD; Andrea Apolo MD; Michael B. Atkins MD; Rick Bangs MBA, PMP; Kathryn E. Beckermann MD, PhD; Joaquim Bellmunt MD, PhD; Stephanie A. Berg DO; Mehmet A. Bilen MD; David Braun MD, PhD; Maria I. Carlo MD; Jason Efstathiou MD, DPhil; Matthew Galsky MD; Petros Grivas MD, PhD; Shilpa Gupta MD; Naomi Haas MD; A. Ari Hakimi MD; Hans Hammers MD, PhD; Daniel Y. C. Heng MSC; Michelle Hirsch MD, PhD; Gopakumar Iyer MD; Eric Jonasch MD; Vadim S. Koshkin MD; Oleksandr Kryvenko MD; Bryan Lewis JD; Roger Li MD; Surena Matin MD; Benjamin Maughan MD, PharmD; David F. McDermott MD; Bradley McGregor MD; Joshua Meeks MD, PhD; Matthew Milowsky MD; Robert Motzer MD; Andrea Necchi MD; Dan Petrylak MD; Sima Porten MD, MPH; Thomas Powles MBBS, MRCP, MD; Brian Rini MD; Brian Shuch MD; Arlene Siefker-Radtke MD; Guru Sonpavde MD; S. Srikala Sridhar MD; Cristina Suarez MD, PhD; Chad Tang MD; Abhishek Tripathi MD; Michiel S. Van Der Heijden MD, PhD; Martin Voss MD; Wenxin Xu MD; Tian Zhang MD; Jonathan Rosenberg MD; Toni K. Choueiri MD

Chromophobe Renal Cell Carcinoma: Emerging Vulnerabilities as a Promise for a New Therapeutic Landscape 淡色细胞肾细胞癌：新兴的易损性作为新治疗格局的希望

Critical Reviews in Oncology/Hematology

IF0

2025-10-22

PREAI

Samer Salem; Michel Alchoueiry; Wenxin Xu; Elizabeth P. Henske

More Than Causes: Unveiling Bidirectional Relationships Between Maladaptive Cognitive Emotion Regulation Strategies and Internalizing Problems in Adolescents 超越原因：揭示青少年不良认知情绪调节策略与内部化问题之间的双向关系

Journal of Adolescence

IF3.2

2025-10-16

PREAI

Jianjun Huang; Yueqin Hui; Yuxin Xie; Yuan Feng; Wenxin Xu; Jin-Liang Wang

HMOX1+ macrophages determine immunosuppressive microenvironment and immunotherapy efficacy in hepatocellular carcinoma HMOX1+ 巨噬细胞决定肝细胞癌的免疫抑制微环境及免疫治疗效果

Hepatology Communications

IF4.6

2025-10-14

OAAI

Du, Yabing; Xu, Wenxin; Liu, Zhenkun; Wen, Peihao; Song, Ruifeng; Hao, Weiwei; Liu, Yating; Zhao, Xinlei; Gu, Meiying; Weng, Jialei; He, Wei

Plasma proteomic profiling reveals distinct mitochondrial signatures in chromophobe renal cell carcinoma 血浆蛋白质组学分析揭示了嗜色性肾细胞癌中独特的线粒体特征

ONCOLOGIST

IF4.2

2025-10-01

OAAI

Steiner, Clara; Mansour, Hadi; Bzeih, Wafaa; Han, Tiegang; Saad, Eddy; Williams, Jessica F.; Hirsch, Michelle S.; Elon, Yehonatan; Dicker, Adam P.; Choueri, Toni; Henske, Elizabeth P.; Xu, Wenxin (Vincent)

Lymphocyte heat shock signature predicts response to immune checkpoint blockade in renal cell carcinoma 淋巴细胞热休克特征可预测肾细胞癌对免疫检查点抑制剂的应答

ONCOLOGIST

IF4.2

2025-10-01

OAAI

Burns, Ethan; Kashima, Soki; Rout, Rishabh; Hugaboom, Miya; Ye, Zhaochen; Schindler, Nicholas; Dighe, Anasuya; Sun, Maxine; Lee, Gwo-Shu Mary; Xu, Wenxin (Vincent); Atkins, Michael B.; Signoretti, Sabina; McGregor, Bradley A.; McKay, Rana; Choueri, Toni; Braun, David

Integrative clinical, genomic, transcriptomic, and immunopathologic characterization of circulating KIM-1 in metastatic RCC 整合临床、基因组学、转录组学和免疫病理学特征，对转移性RCC外周血中KIM-1的综合性研究

ONCOLOGIST

IF4.2

2025-10-01

OAAI

Machaalani, Marc; Saliby, Renee Maria; Zhong, Caiwei; Saad, Eddy; Steiner, Clara; Yekeduz, Emre; Ascione, Liliana; Saleh, Mustafa; Masri, Jad El; Barrios, Pablo; Liu, Xiaowen; Cai, Ti; Sun, Maxine; Lee, Gwo-Shu Mary; Xie, Wanling; Signoretti, Sabina; McDermott, David; Choueri, Toni; Xu, Wenxin (Vincent)

Tumor matrix directed IL12/A3 fusion cytokine secreted by CD70-CAR NK cells markedly enhances anti-ccRCC responses with limited systemic exposure 肿瘤基质引导的IL12/A3融合细胞因子由CD70-CAR NK细胞分泌，可显著增强抗ccRCC反应，且全身暴露有限。

ONCOLOGIST

IF4.2

2025-10-01

OAAI

Liu, Fuguo; Deng, Xinyu; Nguyen, Maily; Tarannum, Mubin; Yang, Shaobo; Dulery, Remy; Chen, Jianzhu; Xu, Wenxin (Vincent); Choueri, Toni; Romee, Rizwan

Single-cell dissection of immunosuppressive myeloid subclusters driving resistance to immune checkpoint therapy in renal cell carcinoma (RCC)单细胞解析驱动肾细胞癌（RCC）对免疫检查点疗法产生耐药性的免疫抑制性髓系亚群。

ONCOLOGIST

IF4.2

2025-10-01

OAAI

Kashima, Soki; Rout, Rishabh; Hugaboom, Miya; Ye, Zhaochen; Schindler, Nicholas; Dighe, Anasuya; Sun, Maxine; Lee, Gwo-Shu Mary; Xu, Wenxin (Vincent); Signoretti, Sabina; McGregor, Bradley A.; McKay, Rana; Choueri, Toni; Braun, David

24TGF-Beta alters CD8+T cell phenotype and drives resistance to immune checkpoint inhibitors (ICI) in renal cell carcinoma (RCC)24TGF-Beta改变了CD8+T细胞表型，并驱动肾细胞癌（RCC）对免疫检查点抑制剂（ICI）产生耐药性。

ONCOLOGIST

IF4.2

2025-10-01

OAAI

Rout, Rishabh; Kashima, Soki; Hugaboom, Miya; Ye, Zhaochen; Schindler, Nicholas; Dighe, Anasuya; Sun, Maxine; Lee, Gwo-Shu Mary; Xu, Wenxin (Vincent); Signoretti, Sabina; McGregor, Bradley A.; McKay, Rana; Choueri, Toni; Braun, David

LASER-a phase 2 trial of 177Lu-PSMA-617 as systemic therapy for renal cell carcinoma (NCT06964958)LASER-a：177Lu-PSMA-617作为系统性疗法治疗肾细胞癌的2期临床试验（NCT06964958）

ONCOLOGIST

IF4.2

2025-10-01

OAAI

Ravi, Praful; Xie, Wanling; Berg, Stephanie; Serzan, Michael; Thapa, Bicky; Viswanathan, Srinivas; Xu, Wenxin (Vincent); Mcgregor, Bradley A.; Choueri, Toni; Jacene, Heather

A phase 0 pilot study of memory-like natural killer (NK) cell immune therapy in patients with renal cell carcinoma or urothelial carcinoma (NCT06318871)一项关于记忆样自然杀伤（NK）细胞免疫疗法在肾细胞癌或尿路上皮癌患者中的0期探索性研究（NCT06318871）

ONCOLOGIST

IF4.2

2025-10-01

OAAI

Xu, Wenxin (Vincent); Xie, Wanling; Liu, Fuguo; Birch, Grace; Welch, Casey; Nguyen, Maily; Stanojevic, Mila; Viswanathan, Srinivas; McGregor, Bradley A.; Ritz, Jerome; Braun, David; Nikiforow, Sarah; Romee, Rizwan; Choueri, Toni

Circulating kidney injury molecule-1 (KIM-1) and association with outcome to adjuvant immunotherapy in renal cell carcinoma 循环性肾损伤分子-1 (KIM-1) 与辅助性免疫疗法在肾细胞癌中的预后关联

Annals of Oncology

IF65.4

2025-08-28

OAAI

B.I. Rini; L. Albiges; X. Tang; H. Koeppen; A. Bex; C. Suárez; R. Uzzo; H. Hamidi; Z.J. Assaf; S. Dubey; E.T. Goluboff; C. Carter; S.K. Pal; R. Banchereau; W. Xu; M.A. Huseni

KIM-1 as a Prognostic Marker in Renal Cell Carcinoma KIM-1作为肾细胞癌的预后标志物

European Urology Focus

IF5.6

2025-07-01

PREAI

Clara Steiner; Marc Machaalani; Joseph V. Bonventre; David F. McDermott; Toni K. Choueiri; Wenxin Xu

CLDN4 palmitoylation promotes hepatic-to-biliary lineage transition and lenvatinib resistance in hepatocellular carcinoma CLDN4棕榈酰化促进肝细胞癌中肝向胆管细胞分化谱系转换及仑伐替尼耐药。

Cell Reports Medicine

IF10.6

2025-06-30

OAAI

Minghao Xu; Yimin Zheng; Junbo Chen; Chao Gao; Miao Zhu; Aying Ma; Bugang Liang; Wenxin Xu; Jia Fan; Haibo Zhou; Aiwu Ke; Yinghao Shen

Integration of Single-Cell RNA Sequencing Data and Bulk Sequencing Data to Characterise the CD8+T-Cell Exhaustion Mediated Immune Microenvironment in CRC 整合单细胞RNA测序数据和 bulk sequencing 数据以表征CRC中由CD8+T细胞耗竭介导的免疫微环境

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IF4.2

2025-05-12

OAAI

Ling, Xiao-Hua; Chen, Gang; Liu, Nan-Nan; Xu, Wen-Xin; Ding, Ming-Feng

Progressive natural killer cell dysfunction in advanced-stage clear-cell renal cell carcinoma and association with clinical outcomes

ESMO OPEN

IF8.3

2025-02-01

PREAI

Xu, W.; Birch, G.; Meliki, A.; Moritz, V.; Bharadwaj, M.; Schindler, N. R.; Labaki, C.; Saliby, R. M.; Dinh, K.; Horst, J. T.; Sun, M.; Kashima, S.; Hugaboom, M.; Dighe, A.; Machaalani, M.; Lee, G. -s. m.; Hurwitz, M.; Mcgregor, B. A.; Hirsch, M. S.; Shukla, S. A.; Mcdermott, D. F.; Signoretti, S.; Romee, R.; Choueiri, T. K.; Braun, D. A.

研究方向