未登录 STEM-PD trial protocol: a multi-centre, single-arm, first-in-human, dose-escalation trial, investigating the safety and tolerability of intraputamenal transplantation of human embryonic stem cell-derived dopaminergic cells for Parkinson's disease STEM-PD试验方案：一项多中心、单臂、首个人类、剂量递增试验，旨在研究向豆状核内移植人胚胎干细胞来源的多巴胺能细胞治疗帕金森病的安全性和耐受性。 Paul, Gesine; Bjartmarz, Hjalmar; Bjorklund, Anders; Cutting, Emma; Evans, Amy; Harry, Bronwen; Hansson, Oskar; Kayhanian, Saeed; Kirkeby, Agnete; Lao-Kim, Nicholas; Lindvall, Olle; Nelander, Jenny; Piccini, Paola; Smith, Ruben; Ullen, Susann; Van Vliet, Trinette; Widner, Hakan; Parmar, Malin; Barker, Roger A. 分享 收藏
The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease TransEuro开放标签试验：人类胎儿腹侧中脑移植治疗中度帕金森病患者的临床研究 Barker, Roger A.; Lao-Kaim, Nicholas P.; Guzman, Natalie Valle; Athauda, Dilan; Bjartmarz, Hjalmar; Bjoerklund, Anders; Church, Alistair; Cutting, Emma; Daft, Danielle; Dayal, Viswas; Dunnett, Stephen; Evans, Amy; Grealish, Shane; Hannaway, Naomi; He, Xiaoling; Hewitt, Sam; Kefalopoulou, Zinovia; Mahlknecht, Philipp; Martin-Bastida, Antonio; Farrell, Krista; Moore, Sarah; Bulstrode, Harry; Nakornchai, Tagore; Nelander-Wahlestedt, Jenny; Roupe, Linnea; Paul, Gesine; Peall, Kathryn; Rosser, Anne; Roca-Fernandez, Adriana; Rowlands, Sophie; Mcgorrian, Anne-Marie; Scherf, Caroline; Vinh, Ngoc Nga; Roberton, Victoria; Kelly, Claire; Lelos, Mariah; Torres, Eduardo; Shires, Kate; Hills, Rachel; Williams, Debbie; Roussakis, Andreas-Antonios; Sibley, Krista; Tyers, Pamela; Wijeyekoon, Ruwani; Williams-Gray, Caroline; Foltynie, Thomas; Piccini, Paola; Morris, Robert; Lazic, Stanley E.; Lindvall, Olle; Parmar, Malin; Widner, Hakan 分享 收藏
Mapping the distribution of neurotransmitters to resting-state functional connectivity in Parkinson's disease 将神经递质分布映射到帕金森病中的静息态功能连接 Li, Weihua; Lao-Kaim, Nicholas P.; Li, Runtian; Martin-Bastida, Antonio; Roussakis, Andreas-Antonios; Searle, Graham E.; Valle-Guzman, Natalie; Dayal, Viswas; Athauda, Dilan; Kefalopoulou, Zinovia; Mahlknecht, Philipp; Church, Alistair; Peall, Kathryn J.; Widner, Hakan; Paul, Gesine; Foltynie, Tom; Barker, Roger A.; Piccini, Paola 分享 收藏
Embedding Patient Input in Outcome Measures for Long-Term Disease-Modifying Parkinson Disease Trials Gonzalez-Robles, Cristina; Bartlett, Michele; Burnell, Matthew; Clarke, Caroline S.; Haar, Shlomi; Hu, Michele T.; Huxford, Brook; Jha, Ashwani; Lawton, Michael; Noyce, Alastair; Piccini, Paola; Pushparatnam, Kuhan; Rochester, Lynn; Siu, Carroll; van Wamelen, Daniel; Williams-Gray, Caroline H.; Zeissler, Marie-Louise; Zetterberg, Henrik; Carroll, Camille B.; Foltynie, Thomas; Weil, Rimona S.; Schrag, Anette 分享 收藏
Outcome Measures for Disease-Modifying Trials in Parkinson's Disease: Consensus Paper by the EJS ACT-PD Multi-Arm Multi-Stage Trial Initiative Gonzalez-Robles, Cristina; Weil, Rimona S.; van Wamelen, Daniel; Bartlett, Michele; Burnell, Matthew; Clarke, Caroline S.; Hu, Michele T.; Huxford, Brook; Jha, Ashwani; Lambert, Christian; Lawton, Michael; Mills, Georgia; Noyce, Alastair; Piccini, Paola; Pushparatnam, Kuhan; Rochester, Lynn; Siu, Carroll; Williams-Gray, Caroline H.; Zeissler, Marie-Louise; Zetterberg, Henrik; Carroll, Camille B.; Foltynie, Thomas; Schrag, Anette 分享 收藏
A PET-CT study on neuroinflammation in Huntington's disease patients participating in a randomized trial with laquinimod 参加拉喹莫德随机试验的亨廷顿病患者神经炎症的pet-ct研究 Roussakis, Andreas-Antonios; Gennaro, Marta; Gordon, Mark Forrest; Reilmann, Ralf; Borowsky, Beth; Rynkowski, Gail; Lao-Kaim, Nicholas P.; Papoutsou, Zoe; Savola, Juha-Matti; Hayden, Michael R.; Owen, David R.; Kalk, Nicola; Lingford-Hughes, Anne; Gunn, Roger N.; Searle, Graham; Tabrizi, Sarah J.; Piccini, Paola 分享 收藏
Astrogliosis in aging and Parkinson's disease dementia: a new clinical study with 11C-BU99008 PET Mohamed, Mohamed A.; Zeng, Zhou; Gennaro, Marta; Lao-Kaim, Nicholas P.; Myers, Jim F. M.; Calsolaro, Valeria; Femminella, Grazia Daniela; Tyacke, Robin J.; Martin-Bastida, Antonio; Gunn, Roger N.; Nutt, David J.; Edison, Paul; Piccini, Paola; Roussakis, Andreas-Antonios 分享 收藏
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Neuromelanin-MRI to Quantify and Track Nigral Depigmentation in Parkinson's Disease: A Multicenter Longitudinal Study Using Template-Based Standardized Analysis Xing, Yue; Sapuan, Abdul Halim; Martin-Bastida, Antonio; Naidu, Saadnah; Tench, Christopher; Evans, Jonathan; Sare, Gillian; Schwarz, Stefan T.; Al-Bachari, Sarah; Parkes, Laura M.; Kanavou, Sofia; Raw, Jason; Silverdale, Monty; Bajaj, Nin; Pavese, Nicola; Burn, David; Piccini, Paola; Grosset, Donald G.; Auer, Dorothee P. 分享 收藏
Dissociable effects of age and Parkinson's disease on instruction-based learning Parkin, Beth L.; Daws, Richard E.; Das-Neves, Ines; Violante, Ines R.; Soreq, Eyal; Faisal, A. Aldo; Sandrone, Stefano; Lao-Kaim, Nicholas P.; Martin-Bastida, Antonio; Roussakis, Andreas-Antonios; Piccini, Paola; Hampshire, Adam 分享 收藏
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Longitudinal functional connectivity changes related to dopaminergic decline in Parkinson's disease Li, Weihua; Lao-Kaim, Nick P.; Roussakis, Andreas-Antonios; Martin-Bastida, Antonio; Valle-Guzman, Natalie; Paul, Gesine; Soreq, Eyal; Daws, Richard E.; Foltynie, Tom; Barker, Roger A.; Hampshire, Adam; Piccini, Paola 分享 收藏
Designing stem-cell-based dopamine cell replacement trials for Parkinson's disease 设计基于干细胞的帕金森病多巴胺细胞替代试验 Barker, Roger A.; Farrell, Krista; Guzman, Natalie Valle; He, Xiaoling; Lazic, Stanley E.; Moore, Sarah; Morris, Robert; Tyers, Pamela; Wijeyekoon, Ruwani; Daft, Danielle; Hewitt, Sam; Dayal, Viswas; Foltynie, Thomas; Kefalopoulou, Zinovia; Mahlknecht, Philipp; Lao-Kaim, Nick P.; Piccini, Paola; Bjartmarz, Hjalmar; Bjorklund, Anders; Lindvall, Olle; Nelander-Wahlestedt, Jenny; Parmar, Malin; Paul, Gesine; Widner, Hakan; Church, Alistair; Dunnett, Stephen; Peall, Kathryn; Rosser, Anne; Gurruchaga, Jean Marc; Palfi, Stephane; Piroth, Tobias; Winkler, Christian 分享 收藏
Comparison of phosphodiesterase 10A and dopamine transporter levels as markers of disease burden in early Parkinson's disease Pagano, Gennaro; Niccolini, Flavia; Wilson, Heather; Yousaf, Tayyabah; Khan, Naheed L.; Martino, Davide; Plisson, Christophe; Gunn, Roger N.; Rabiner, Eugenii A.; Piccini, Paola; Foltynie, Thomas; Politis, Marios 分享 收藏
Relationship between neuromelanin and dopamine terminals within the Parkinson's nigrostriatal system Martin-Bastida, Antonio; Lao-Kaim, Nicholas R.; Roussakis, Andreas Antonios; Searle, Graham E.; Xing, Yue; Gunn, Roger N.; Schwarz, Stefan T.; Barker, Roger A.; Auer, Dorothee P.; Piccini, Paola 分享 收藏
Role of Mycobacterium avium lysate INF-, IL-17, and IL-2 ELISPOT assays in diagnosing nontuberculous mycobacteria lymphadenitis in children Della Bella, Chiara; Venturini, Elisabetta; Devente, Savannah; Piccini, Paola; Tapinassi, Simona; Bianchi, Leila; Grassi, Alessia; Benagiano, Marisa; Alnwaisri, Heba F. Mustafa; Montagnani, Carlotta; Chiappini, Elena; Bitter, Wilbert; D'Elios, Mario M.; de Martino, Maurizio; Galli, Luisa 分享 收藏
Outcome of cell suspension allografts in a patient with Huntington's disease Maxan, Alexander; Mason, Sarah; Saint-Pierre, Martine; Smith, Emma; Ho, Aileen; Harrower, Timothy; Watts, Colin; Tai, Yen; Pavese, Nicola; Savage, Julie C.; Tremblay, Marie-Eve; Gould, Peter; Rosser, Anne E.; Dunnett, Stephen B.; Piccini, Paola; Barker, Roger A.; Cicchetti, Francesca 分享 收藏
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