Matthew J. A. Wood - Publications, H-index & Citations

Matthew J. A. Wood

university of oxford

101H指数

580论文数

5.5W被引数

收录论文 217

发表时间

Accurately modeling RNase H-mediated antisense oligonucleotide efficacy 准确模拟RNase H介导的反义寡核苷酸疗效

Molecular Therapy Nucleic Acids

IF6.1

2026-07-07

OAAI

Barney Hill; Maisie R. Jaques; Remya R. Nair; Nicola Whiffin; Matthew J.A. Wood; Stephan J. Sanders; Peter L. Oliver; Alyssa C. Hill; Carlo Rinaldi

Myonuclear Domain-Associated and Central Nucleation-Dependent Spatial Restriction of Dystrophin Protein Expression 肌核域相关及中心核化依赖的 dystrophin 蛋白表达的空域限制

journal of cachexia, sarcopenia and muscle

IF0

2026-04-07

OAAI

Katarzyna Chwalenia; Vivi-Yun Feng; Nicole Hemmer; John C. W. Hildyard; Liberty E. Roskrow; Richard J. Piercy; Eric T. Wang; Annemieke Aartsma-Rus; Maaike van Putten; Matthew J. A. Wood; Thomas C. Roberts

The CTDP1 Founder Variant in CCFDN: Insights into Pathogenesis, Phenotypic Spectrum and Therapeutic Approaches CTDP1奠基者变异在CCFDN中的研究：发病机制、表型谱及治疗方法的见解

International Journal of Molecular Sciences 2026, Vol. 27, Page 34

IF4.9

2025-12-20

OAAI

Iulia Maria Sabau; Alexandra Chera; Victor Gabriel Ungureanu; Mircea Cretu Stancu; Adela Chirita-Emandi; Matthew Wood; Maria Puiu; Octavian Bucur

Targeted BDNF upregulation via upstream open reading frame disruption 通过上游开放阅读框破坏实现靶向BDNF上调

Molecular Therapy

IF12

2025-12-11

OAAI

Ning Feng; Thomas Goedert; Nenad Svrzikapa; Dongnan Yan; Hans J. Friedrichsen; Britt Hanson; Alicia Ljungdahl; Ruxandra Dafinca; Kevin Talbot; Stephan J. Sanders; Dhanu Gupta; Mathew J.A. Wood; Thomas C. Roberts

Biophysical and biological properties of splice-switching oligonucleotides and click conjugates containing LNA-phosphothiotriester linkages 剪接开关寡核苷酸及其含LNA-磷酸硫三酯键的点击偶联物的生物物理和生物学特性

NUCLEIC ACIDS RESEARCH

IF13.1

2025-11-26

PREAI

Dhara, Debashis; Hill, Alyssa C.; Ramesh, Abinaya; Traore, Diallo; Radzikowska-Cieciura, Ewa; Wood, Matthew J. A.; Brown, Tom

Exon skipping peptide-conjugated morpholinos downregulate dynamin 2 to rescue centronuclear myopathy 外显子跳跃肽偶联的形态醇核酸类似物通过下调动力蛋白2来拯救中心核肌病

BRAIN

IF11.7

2025-11-01

OAAI

Moschovaki-Filippidou, Foteini; De Carvalho Neves, Juliana; Diedhiou, Nadege; Jad, Yahya; Bohm, Johann; Wood, Matthew J. A.; Varela, Miguel A.; Laporte, Jocelyn

Synthesis, Biological Activity, and Molecular Dynamics Simulations of LNA-Charge Neutral Linkages for Enhanced Splice-Switching Antisense Oligonucleotides LNA-电荷中性连接体的合成、生物活性及分子动力学模拟：用于增强剪接开关反义寡核苷酸

Angewandte Chemie International Edition

IF0

2025-09-21

OAAI

Alice Kennett; Lillian Lie; Martin Flerin; Belma Zengin Kurt; Ysobel R. Baker; Alyssa C. Hill; Abinaya Ramesh; Matthew J.A. Wood; Debashis Dhara; Afaf H. El-Sagheer; Fernanda Duarte; Tom Brown

AAV microdystrophin gene replacement therapy for Duchenne muscular dystrophy: progress and prospects AAV微抗肌营养不良蛋白基因替代疗法治疗杜氏肌营养不良症：进展与展望

Gene Therapy

IF4.5

2025-08-15

OAAI

Katarzyna Chwalenia; Vivi-Yun Feng; Nicole Hemmer; Hans J. Friedrichsen; Ioulia Vorobieva; Matthew J. A. Wood; Thomas C. Roberts

miR-107 represses DMPK and is sequestered by CUG repeats triggering the MSI2/miR-7 pathogenesis axis in myotonic dystrophy miR-107 抑制 DMPK，并被 CUG 重复序列捕获，从而触发强直性肌营养不良症中的 MSI2/miR-7 致病轴。

Molecular Therapy Nucleic Acids

IF6.1

2025-06-04

OAAI

N. Moreno; M. Sabater-Arcis; J. Espinosa-Espinosa; L. Mulet-Rivero; E. García-España; J. González-García; D. Seoane-Miraz; M.J.A. Wood; M.A. Varela; J. Ohana; T. Sevilla; M. Perez Alonso; A. Bargiela; R. Artero

uORF-targeting steric block antisense oligonucleotides do not reproducibly increase RNASEH1 expression 靶向uORF的空间阻断反义寡核苷酸不能重复增加RNASEH1的表达

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2025-03-01

OAAI

Ahlskog, Nina; Svrzikapa, Nenad; Abuhamdah, Rushdie; Kye, Mahnseok; Jad, Yahya; Feng, Ning; Hanson, Britt; Wood, Matthew J. A.; Roberts, Thomas C.

Activation- induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles 活化诱导的thrombospondin-4与thrombospondin-1协同作用，共同构建细胞毒性超分子攻击颗粒。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-02-04

OAAI

Cassioli, Chiara; Capitani, Nagaja; Staton, Claire C.; Schirra, Claudia; Finetti, Francesca; Onnis, Anna; Alawar, Nadia; Tu, Szu - Min; Lopresti, Ludovica; Tatangelo, Vanessa; Tangredi, Carmela; Valvo, Salvatore; Chang, Hsin - Fang; Miccoli, Annachiara; Compeer, Ewoud B.; Nicholls, Jemma; Blazar, Bruce R.; Marotta, Giuseppe; Wood, Matthew J. A.; Trentin, Livio; Patrussi, Laura; Becherer, Ute; Baldari, Cosima T.

Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in BTK/Tec double deficient X-linked agammaglobulinemia model 穿膜肽偶联的剪接转换寡核苷酸可缓解BTK/Tec双缺陷型X连锁无丙种球蛋白血症模型的表型

RSC CHEMICAL BIOLOGY

IF3.1

2025-01-01

OAAI

Bestas, Burcu; Estupinan, H. Yesid; Wang, Qing; Kharazi, Shabnam; He, Chenfei; K. Mohammad, Dara; Gupta, Dhanu; Wiklander, Oscar P. B.; Lehto, Taavi; Lundin, Karin E.; Berglof, Anna; Karlsson, Mikael C. I.; Abendroth, Frank; El Andaloussi, Samir; Gait, Michael J.; Wood, Matthew J. A.; Leumann, Christian J.; Stetsenko, Dmitry A.; Mansson, Robert; Wengel, Jesper; Zain, Rula; Smith, C. I. Edvard

Synthesis, Biophysical and Biological Evaluation of Splice-Switching Oligonucleotides with Multiple LNA-Phosphothiotriester Backbones

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-10-14

OAAI

Dhara, Debashis; Hill, Alyssa C.; Ramesh, Abinaya; Wood, Matthew J. A.; El-Sagheer, Afaf H.; Brown, Tom

TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition

ACTA NEUROPATHOLOGICA

IF9.3

2024-09-21

OAAI

Torres, Pascual; Rico-Rios, Santiago; Ceron-Codorniu, Miriam; Santacreu-Vilaseca, Marta; Seoane-Miraz, David; Jad, Yahya; Ayala, Victoria; Marino, Guillermo; Beltran, Maria; Miralles, Maria P.; Andres-Benito, Pol; Fernandez-Irigoyen, Joaquin; Santamaria, Enrique; Lopez-Otin, Carlos; Soler, Rosa M.; Povedano, Monica; Ferrer, Isidro; Pamplona, Reinald; Wood, Matthew J. A.; Varela, Miguel A.; Portero-Otin, Manuel

Peptide-conjugated antimiRs improve myotonic dystrophy type 1 phenotypes by promoting endogenous MBNL1 expression

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2023-12-01

OAAI

Gonzalez-Martinez, Irene; Cerro-Herreros, Estefania; Moreno, Nerea; Garcia-Rey, Andrea; Espinosa-Espinosa, Jorge; Carrascosa-Saez, Marc; Piqueras-Losilla, Diego; Arzumanov, Andrey; Seoane-Miraz, David; Jad, Yahya; Raz, Richard; Wood, Matthew J.; Varela, Miguel A.; Llamusi, Beatriz; Artero, Ruben

A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models

HUMAN MOLECULAR GENETICS

IF3.2

2023-11-08

OAAI

Hoolachan, Joseph M.; Mccallion, Eve; Sutton, Emma R.; Cetin, Ozge; Pacheco-Torres, Paloma; Dimitriadi, Maria; Sari, Suat; Miller, Gavin J.; Okoh, Magnus; Walter, Lisa M.; Claus, Peter; Wood, Matthew J. A.; Tonge, Daniel P.; Bowerman, Melissa

An Induced Pluripotent Stem Cell-Derived Human Blood-Brain Barrier (BBB) Model to Test the Crossing by Adeno-Associated Virus (AAV) Vectors and Antisense Oligonucleotides

BIOMEDICINES

IF3.9

2023-10-04

OAAI

Selvakumaran, Jamuna; Ursu, Simona; Bowerman, Melissa; Lu-Nguyen, Ngoc; Wood, Matthew J.; Malerba, Alberto; Yanez-Munoz, Rafael J.

PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice

EMBO MOLECULAR MEDICINE

IF8.3

2023-09-19

OAAI

Kordala, Anna J.; Stoodley, Jessica; Ahlskog, Nina; Hanifi, Muhammad; Garcia Guerra, Antonio; Bhomra, Amarjit; Lim, Wooi Fang; Murray, Lyndsay M.; Talbot, Kevin; Hammond, Suzan M.; Wood, Matthew J. A.; Rinaldi, Carlo

Modulation of Pro-Inflammatory IL-6 Trans-Signaling Axis by Splice Switching Oligonucleotides as a Therapeutic Modality in Inflammation

CELLS

IF5.2

2023-09-15

OAAI

Gupta, Dhanu; Orehek, Sara; Turunen, Janne; O'Donovan, Liz; Gait, Michael J.; El-Andaloussi, Samir; Wood, Matthew J. A.

EV-mediated promotion of myogenic differentiation is dependent on dose , collection medium, and isolation method EV介导的肌源性分化的促进取决于剂量，收集介质和隔离方法

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2023-09-01

OAAI

Hanson, Britt; Vorobieva, Ioulia; Zheng, Wenyi; Conceicao, Mariana; Lomonosova, Yulia; Mager, Imre; Puri, Pier Lorenzo; El Andaloussi, Samir; Wood, Matthew J. A.; Roberts, Thomas C.

研究方向