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N

Nunzio Bottini

harvard medical school

55H指数
264论文数
1.4W被引数
收录论文 122
发表时间
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A CD57+CD8+T cell subset links T cell cytotoxicity to fibrotic lung disease in systemic sclerosisCD57+CD8+T细胞亚群将T细胞细胞毒性与人系统性硬化症的纤维化肺疾病联系起来
errJournal of Clinical Investigation
IF13.6
err2026-05-01
err0
PREAI
errSasaki, Takanori; Cao, Ye; Sowerby, John M.; Higashioka, Kazuhiko; Marks, Kathryne E.; Elahee, Mehreen; Kamiya, Mari; Dellaripa, Paul F.; Ainsworth, Richard I.; Taylor, Kimberly E.; Bottini, Nunzio; Wolters, Paul; Kim, Edy Y.; Boin, Francesco; Rao, Deepak A.
err分享
err收藏
Rebalancing Inflammation in Arthritis: PEPITEM as a Restorer of Immune Regulation
errArthritis & Rheumatology
IF10.9
err2026-02-05
err0
PREAI
errMattias N.D Svensson PhD; Nunzio Bottini MD PhD
err分享
err收藏
Single-cell analysis reveals peripheral helper T cells in rheumatoid arthritis-related interstitial lung disease
errArthritis & Rheumatology
IF10.9
err2026-02-02
err0
PREAI
errKensuke Suga MD, PhD; Amara Seng MD, PhD; Changfu Yao PhD; Tanyalak Parimon MD; Anvita Singaraju PhD; Edo Israely PhD; Beulah Esther Rani Samuel PhD; Youn Jung Choi PhD; Justyna Fert-Bober PhD; Barry R. Stripp PhD; Paul J. Wolters MD; Jon T. Giles MD, MPH; Peter Chen MD; Nunzio Bottini MD, PhD
err分享
err收藏
Optimization of a synoviocyte-targeted biologic for inflammatory arthritis in combination or bispecific administration with TNF inhibitors针对炎性关节炎的滑膜细胞靶向生物制剂在联合或双特异性给药与TNF抑制剂中的应用优化
errJCI INSIGHT
IF6.1
err2025-11-10
err0
errOAAI
errRamsey, Sterling H.; Zhao, Zixuan; Lee, Megan C.; da Rosa, Thales Hein; Schneider, Ava C.; Bollmann, Miriam; Dada, Nour; Frizzi, Katie E.; Han, May M.; Kim, Jaeyeon; Zoccheddu, Martina; Calcutt, Nigel A.; Firestein, Gary S.; Bryson, James W.; Svensson, Mattias N. D.; Santelli, Eugenio; Stanford, Stephanie M.; Bottini, Nunzio
err分享
err收藏
TH17 cells converted into exTH17 cells sustain rheumatoid-like IL-17–independent inflammatory arthritisTH17细胞转化为exTH17细胞可维持类风湿样IL-17非依赖性炎性关节炎
errScience Immunology
IF16.3
err2025-11-07
err0
PREAI
errMartina Zoccheddu; Kensuke Suga; Amara Seng; Mattias N. D. Svensson; Paramita Dutta; Sanaz Panahandeh; Hadijat-Kubura Moradeke Makinde; Myungja Ro; Yizhou Wang; Hyobin Kim; Zbigniew Mikulski; Katarzyna Dobaczewska; Francesca Ingegnoli; Ruth Minsha; John F. Seagrist; Mary Carns; Kathleen Aren; Salina Dominguez; Mohammad Daud Khan; Angela Denn; Roberto Caporali; Pietro Simone Randelli; David A. McBride; Arthur M. Mandelin; Carla Marie Cuda; Zhiping Paul Wang; Jason H. Moore; Nisarg J. Shah; Kyoung Jae Won; Deborah R. Winter; Ferhat Ay; Harris Perlman; Nunzio Bottini
err分享
err收藏
Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in micePTPN2功能获得性突变与患者微生物组的相互作用促进小鼠自身免疫性关节炎
errJournal of Autoimmunity
IF7
err2025-08-01
err0
PREAI
errSho Sendo; Allison J. Vela; Myungja Ro; Deepan Thiruppathy; Elizabeth L. Wilkinson; Zixuan Zhao; Wan-Chen Hsieh; Shen Yang; Roxana Coras; Anne-Sophie Bergot; Monica Guma; Anders Nguyen; David A. McBride; Suzanne Devkota; Ranjeny Thomas; Nisarg J. Shah; Mattias N.D. Svensson; Karsten Zengler; Stephanie M. Stanford; Nunzio Bottini
err分享
err收藏
Disease modifying biomaterials for modulating mechanical allodynia in a preclinical model of rheumatoid arthritis用于调节类风湿关节炎前临床模型中机械性异常疼痛的疾病修饰生物材料
errBioengineering & Translational Medicine
IF5.7
err2025-07-31
err0
errOAAI
errMaksim Dolmat; Julia Borges Paes Lemes; Wade T. Johnson; Elizabeth L. Wilkinson; Tony L. Yaksh; Nunzio Bottini; Nisarg J. Shah
err分享
err收藏
Modulation of the PTPRS proteoglycan switch by antibodies binding to the membrane-proximal fibronectin-type III domainPTPRS蛋白聚糖开关通过结合膜近端纤连蛋白III型结构域的抗体进行调节
errJournal of Biological Chemistry
IF3.9
err2025-07-10
err0
errOAAI
errThales Hein Da Rosa; Sterling H. Ramsey; Judy J. Lee; Natalia Y. Kozlova; Zixuan Zhao; Jaeyeon Kim; Ava C. Schneider; Sheng Li; Madhusudhanarao Katiki; Gary S. Firestein; Ramachandran Murali; Eugenio Santelli; Stephanie M. Stanford; Nunzio Bottini
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err收藏
REPLY: Macrophage Activation in Systemic Sclerosis回复：系统性硬化症中的巨噬细胞活化
errJACC-BASIC TO TRANSLATIONAL SCIENCE
IF7.2
err2025-04-01
err0
errOAAI
errJones, Xaviar M.; Soussi, Salwa; Bottini, Nunzio; Ibrahim, Ahmed G. E.; Marban, Eduardo
err分享
err收藏
Transcriptomics of SGLT2-positive early proximal tubule segments in mice: response to type 1 diabetes, SGLT1/2 inhibition, or GLP1 receptor agonism小鼠SGLT2-positive早期近端小管片段的转录组学: 对1型糖尿病，SGLT1/2抑制或GLP1受体激动的反应
errAMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
IF3.4
err2025-01-01
err0
PREAI
errKim, Young Chul; Das, Vivek; Kanoo, Sadhana; Yao, Huazhen; Stanford, Stephanie M.; Bottini, Nunzio; Karihaloo, Anil; Vallon, Volker
err分享
err收藏
Macrophages Contribute to Cardiac Fibrosis and Diastolic Dysfunction in Systemic Sclerosis巨噬细胞参与系统性硬化症中的心肌纤维化和舒张功能障碍
errJACC-BASIC TO TRANSLATIONAL SCIENCE
IF7.2
err2024-12-01
err3
errOAAI
errJones, Xaviar M.; Rogers, Russell G.; Tsi, Kara; Mesquita, Thassio; Marchevsky, Alberto; Ciullo, Alessandra; Soussi, Salwa; Bottini, Nunzio; Ibrahim, Ahmed G. E.; Marban, Eduardo
err分享
err收藏
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-06-01
err2
errOAAI
errZhuang, Chuling; Yang, Shen; Gonzalez, Carlos G.; Ainsworth, Richard I.; Li, Sheng; Kobayashi, Masumi Takayama; Wierzbicki, Igor; Rossitto, Leigh-Ana M.; Wen, Yutao; Peti, Wolfgang; Stanford, Stephanie M.; Gonzalez, David J.; Murali, Ramachandran; Santelli, Eugenio; Bottini, Nunzio
err分享
err收藏
Laser Capture Microscopy RNA Sequencing for Topological Mapping of Synovial Pathology During Rheumatoid Arthritis
errARTHRITIS & RHEUMATOLOGY
IF10.9
err2024-05-21
err0
PREAI
errVan Espen, Benjamin; Prideaux, E. Barton; Wilson, Andrew R.; Machado, Camilla R. L.; Sendo, Sho; Parker, James; Seumois, Gregory; Sacchetti, Cristiano; Belongia, Anna C.; Perumal, Narayanan B.; Vijayanand, Pandurangan; Linnik, Matthew D.; Benschop, Robert J.; Wang, Wei; Bottini, Nunzio; Firestein, Gary S.; Stanford, Stephanie M.
err分享
err收藏
The therapeutic potential of immunoengineering for systemic autoimmunity
errNATURE REVIEWS RHEUMATOLOGY
IF32.7
err2024-02-21
err4
PREAI
errMcbride, David A.; Jones, Ryan M.; Bottini, Nunzio; Shah, Nisarg J.
err分享
err收藏
Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy
errSCIENCE ADVANCES
IF12.5
err2024-02-02
err2
errOAAI
errStanford, Stephanie M.; Nguyen, Tiffany P.; Chang, Joseph; Zhao, Zixuan; Hackman, G. Lavender; Santelli, Eugenio; Sanders, Colton M.; Katiki, Madhusudhanarao; Dondossola, Eleonora; Brauer, Brooke L.; Diaz, Michael A.; Zhan, Yuan; Ramsey, Sterling H.; Watson, Philip A.; Sankaran, Banumathi; Paindelli, Claudia; Parietti, Vanessa; Mikos, Antonios G.; Lodi, Alessia; Bagrodia, Aditya; Elliott, Andrew; Mckay, Rana R.; Murali, Ramachandran; Tiziani, Stefano; Kettenbach, Arminja N.; Bottini, Nunzio
err分享
err收藏
ABCD of IA: A multi-scale agent-based model of T cell activation in inflammatory arthritis
errBIOMATERIALS SCIENCE
IF5.7
err2024-01-01
err0
PREAI
errMcbride, David A.; Wang, James S.; Johnson, Wade T.; Bottini, Nunzio; Shah, Nisarg J.
err分享
err收藏
Inhibiting the Inhibitor in Synovial Macrophages and Cancer Immunotherapy-Associated Inflammatory Arthritis
errARTHRITIS & RHEUMATOLOGY
IF10.9
err2023-12-18
err1
PREAI
errShah, Nisarg J.; Bottini, Nunzio
err分享
err收藏
Immunomodulatory Nanoparticles for Modulating Arthritis Flares
errACS NANO
IF16
err2023-11-28
err6
PREAI
errJohnson, Wade T.; McBride, David; Kerr, Matthew; Nguyen, Anders; Zoccheddu, Martina; Bollmann, Miriam; Wei, Xiaofu; Jones, Ryan M.; Wang, Wei; Svensson, Mattias N. D.; Bottini, Nunzio; Shah, Nisarg J.
err分享
err收藏
Revisiting VH1 phosphatase at the time of monkeypox: back to the spotlight
errBIOCHEMICAL SOCIETY TRANSACTIONS
IF4.3
err2023-07-06
err2
PREAI
errBottini, Angel; Pacheco, Diana R. D. C. G.; Forti, Fabio L.; Bottini, Nunzio
err分享
err收藏
Clustering of phosphatase RPTPα promotes Src signaling and the arthritogenic action of synovial fibroblasts
errSCIENCE SIGNALING
IF6.6
err2023-07-04
err2
PREAI
errSendo, Sho; Kiosses, William B.; Yang, Shen; Wu, Dennis J.; Lee, Daniel W. K.; Liu, Lin; Aschner, Yael; Vela, Allison J.; Downey, Gregory P.; Santelli, Eugenio; Bottini, Nunzio
err分享
err收藏

研究方向

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合作学者
合作期刊
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John R. Yates
H 指数: 188 · 论文数: 1.5K
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Vijay K. Kuchroo
H 指数: 157 · 论文数: 682
J
John A. Todd
H 指数: 142 · 论文数: 1.1K
K
Klaus Ley
H 指数: 137 · 论文数: 969
T
Tony L. Yaksh
H 指数: 129 · 论文数: 967
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