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A role for astrocytic miR-129-5p in frontotemporal dementia 星形胶质细胞miR-129-5p在额颞叶痴呆中的作用 Kaurani, Lalit; Pradhan, Ranjit; Schroeder, Sophie; Burkhardt, Susanne; Schuetz, Anna-Lena; Krueger, Dennis M.; Pena, Tonatiuh; Heutink, Peter; Sananbenesi, Farahnaz; Fischer, Andre 分享 收藏
Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes Yin, Jiang-An; Frick, Lukas; Scheidmann, Manuel C.; Liu, Tingting; Trevisan, Chiara; Dhingra, Ashutosh; Spinelli, Anna; Wu, Yancheng; Yao, Longping; Vena, Dalila Laura; Knapp, Britta; Guo, Jingjing; De Cecco, Elena; Ging, Kathi; Armani, Andrea; Oakeley, Edward J.; Nigsch, Florian; Jenzer, Joel; Haegele, Jasmin; Pikusa, Michal; Taeger, Joachim; Rodriguez-Nieto, Salvador; Bouris, Vangelis; Ribeiro, Rafaela; Baroni, Federico; Bedi, Manmeet Sakshi; Berry, Scott; Losa, Marco; Hornemann, Simone; Kampmann, Martin; Pelkmans, Lucas; Hoepfner, Dominic; Heutink, Peter; Aguzzi, Adriano 分享 收藏
Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2 转录因子USF2和ONECUT2对 β-葡糖脑苷脂酶的直接和间接调控 Ging, Kathi; Frick, Lukas; Schlachetzki, Johannes; Armani, Andrea; Zhu, Yanping; Gilormini, Pierre-Andre; Dhingra, Ashutosh; Boeck, Desiree; Marques, Ana; Deen, Matthew; Chen, Xi; Serdiuk, Tetiana; Trevisan, Chiara; Sellitto, Stefano; Pisano, Claudio; Glass, Christopher K.; Heutink, Peter; Yin, Jiang-An; Vocadlo, David J.; Aguzzi, Adriano 分享 收藏
Dopamine Pathway and Parkinson's Risk Variants Are Associated with Levodopa-Induced Dyskinesia 多巴胺通路和帕金森风险变异与左旋多巴诱导的运动障碍相关 Sosero, Yuri L.; Bandres-Ciga, Sara; Ferwerda, Bart; Tocino, Maria T. P.; Belloso, Diaz R.; Gomez-Garre, Pilar; Faouzi, Johann; Taba, Pille; Pavelka, Lukas; Marques, Taina M.; Gomes, Clarissa P. C.; Kolodkin, Alexey; May, Patrick; Milanowski, Lukasz M.; Wszolek, Zbigniew K.; Uitti, Ryan J.; Heutink, Peter; van Hilten, Jacobus J.; Simon, David K.; Eberly, Shirley; Alvarez, Ignacio; Krohn, Lynne; Yu, Eric; Freeman, Kathryn; Rudakou, Uladzislau; Ruskey, Jennifer A.; Asayesh, Farnaz; Menendez-Gonzalez, Manuel; Pastor, Pau; Ross, Owen A.; Krueger, Rejko; Corvol, Jean-Christophe; Koks, Sulev; Mir, Pablo; De Bie, Rob M. A.; Iwaki, Hirotaka; Gan-Or, Ziv 分享 收藏
Team Science Approaches to Unravel Monogenic Parkinson's Disease on a Global Scale Junker, Johanna; Lange, Lara M.; Vollstedt, Eva-Juliane; Roopnarain, Karisha; Doquenia, Maria Leila M.; Annuar, Azlina Ahmad; Avenali, Micol; Bardien, Soraya; Bahr, Natascha; Ellis, Melina; Galandra, Caterina; Gasser, Thomas; Heutink, Peter; Illarionova, Anastasia; Kanana, Yuliia; Sarmiento, Ignacio J. Keller; Kumar, Kishore R.; Lim, Shen-Yang; Madoev, Harutyun; Mata, Ignacio F.; Mencacci, Niccolo E.; Nalls, Mike A.; Padmanabhan, Shalini; Shambetova, Cholpon; Solle, J. C.; Tan, Ai-Huey; Trinh, Joanne; Valente, Enza Maria; Singleton, Andrew; Blauwendraat, Cornelis; Lohmann, Katja; Fang, Zih-Hua; Klein, Christine 分享 收藏
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS 血浆细胞外囊泡tau和TDP-43作为FTD和ALS的诊断生物标志物 Chatterjee, Madhurima; Ozdemir, Selcuk; Fritz, Christian; Mobius, Wiebke; Kleineidam, Luca; Mandelkow, Eckhard; Biernat, Jacek; Dogdu, Cem; Peters, Oliver; Cosma, Nicoleta Carmen; Wang, Xiao; Schneider, Luisa-Sophia; Priller, Josef; Spruth, Eike; Kuhn, Andrea A.; Krause, Patricia; Klockgether, Thomas; Vogt, Ina R.; Kimmich, Okka; Spottke, Annika; Hoffmann, Daniel C.; Fliessbach, Klaus; Miklitz, Carolin; McCormick, Cornelia; Weydt, Patrick; Falkenburger, Bjorn; Brandt, Moritz; Guenther, Rene; Dinter, Elisabeth; Wiltfang, Jens; Hansen, Niels; Bahr, Mathias; Zerr, Inga; Floel, Agnes; Nestor, Peter J.; Duzel, Emrah; Glanz, Wenzel; Incesoy, Enise; Burger, Katharina; Janowitz, Daniel; Perneczky, Robert; Rauchmann, Boris S.; Hopfner, Franziska; Wagemann, Olivia; Levin, Johannes; Teipel, Stefan; Kilimann, Ingo; Goerss, Doreen; Prudlo, Johannes; Gasser, Thomas; Brockmann, Kathrin; Mengel, David; Zimmermann, Milan; Synofzik, Matthis; Wilke, Carlo; Selma-Gonzalez, Judit; Turon-Sans, Janina; Santos-Santos, Miguel Angel; Alcolea, Daniel; Rubio-Guerra, Sara; Fortea, Juan; Carbayo, Alvaro; Lleo, Alberto; Rojas-Garcia, Ricardo; Illan-Gala, Ignacio; Wagner, Michael; Frommann, Ingo; Roeske, Sandra; Bertram, Lucas; Heneka, Michael T.; Brosseron, Frederic; Ramirez, Alfredo; Schmid, Matthias; Beschorner, Rudi; Halle, Annett; Herms, Jochen; Neumann, Manuela; Barthelemy, Nicolas R.; Bateman, Randall J.; Rizzu, Patrizia; Heutink, Peter; Dols-Icardo, Oriol; Hoeglinger, Guenter; Hermann, Andreas; Schneider, Anja 分享 收藏
Dissecting genetic architecture of rare dystonia: genetic, molecular and clinical insights Atasu, Burcu; Simon-Sanchez, Javier; Hanagasi, Hasmet; Bilgic, Basar; Hauser, Ann-Kathrin; Guven, Gamze; Heutink, Peter; Gasser, Thomas; Lohmann, Ebba 分享 收藏
Harnessing diversity to study Alzheimer's disease: A new iPSC resource from the NIH CARD and ADNI Screven, Laurel A.; Pantazis, Caroline B.; Andersh, Katherine M.; Hong, Samantha; Vitale, Dan; Lara, Erika; Ku, Ray Yueh; Heutink, Peter; Meyer, Jason; Faber, Kelley; Nho, Kwangsik; Saykin, Andrew J.; Foroud, Tatiana M.; Nalls, Mike A.; Blauwendraat, Cornelis; Singleton, Andrew; Narayan, Priyanka S. 分享 收藏
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Elucidating causative gene variants in hereditary Parkinson's disease in the Global Parkinson's Genetics Program (GP2) (vol 9, 100, 2023) 在全球帕金森遗传学计划 (GP2) 中阐明遗传性帕金森病的致病基因变异 (第9卷，100，2023) Lange, Lara M.; Avenali, Micol; Ellis, Melina; Illarionova, Anastasia; Sarmiento, Ignacio J. Keller; Tan, Ai-Huey; Madoev, Harutyun; Galandra, Caterina; Junker, Johanna; Roopnarain, Karisha; Solle, Justin; Wegel, Claire; Fang, Zih-Hua; Heutink, Peter; Kumar, Kishore R.; Lim, Shen-Yang; Valente, Enza Maria; Nalls, Mike; Blauwendraat, Cornelis; Singleton, Andrew; Mencacci, Niccolo; Lohmann, Katja; Klein, Christine; Gatto, Emilia M.; Kauffman, Marcelo; Khachatryan, Samson; Tavadyan, Zaruhi; Shepherd, Claire E.; Hunter, Julie; Kumar, Kishore; Ellis, Melina; Renteria, Miguel E.; Koks, Sulev; Zimprich, Alexander; Schumacher-Schuh, Artur F.; Rieder, Carlos; Awad, Paula Saffie; Tumas, Vitor; Camargos, Sarah; Fon, Edward A.; Monchi, Oury; Fon, Ted; Galleguillos, Benjamin Pizarro; Miranda, Marcelo; Bustamante, Maria Leonor; Olguin, Patricio; Chana, Pedro; Tang, Beisha; Shang, Huifang; Guo, Jifeng; Chan, Piu; Luo, Wei; Arboleda, Gonzalo; Orozco, Jorge; del Rio, Marlene Jimenez; Hernandez, Alvaro; Salama, Mohamed; Kamel, Walaa A.; Zewde, Yared Z.; Brice, Alexis; Corvol, Jean-Christophe; Westenberger, Ana; Illarionova, Anastasia; Mollenhauer, Brit; Klein, Christine; Vollstedt, Eva-Juliane; Hopfner, Franziska; Hoglinger, Gunter; Madoev, Harutyun; Trinh, Joanne; Junker, Johanna; Lohmann, Katja; Lange, Lara M.; Sharma, Manu; Groppa, Sergio; Gasser, Thomas; Fang, Zih-Hua; Akpalu, Albert; Xiromerisiou, Georgia; Hadjigorgiou, Georgios; Dagklis, Ioannis; Tarnanas, Ioannis; Stefanis, Leonidas; Stamelou, Maria; Dadiotis, Efthymios; Medina, Alex; Chan, Germaine Hiu-Fai; Ip, Nancy; Cheung, Nelson Yuk-Fai; Chan, Phillip; Zhou, Xiaopu; Kishore, Asha; Kp, Divya; Pal, Pramod; Kukkle, Prashanth Lingappa; Rajan, Roopa; Borgohain, Rupam; Salari, Mehri; Quattrone, Andrea; Valente, Enza Maria; Parnetti, Lucilla; Avenali, Micol; Schirinzi, Tommaso; Funayama, Manabu; Hattori, Nobutaka; Shiraishi, Tomotaka; Karimova, Altynay; Kaishibayeva, Gulnaz; Shambetova, Cholpon; Kruger, Rejko; Tan, Ai Huey; Ahmad-Annuar, Azlina; Norlinah, Mohamed Ibrahim; Murad, Nor Azian Abdul; Ibrahim, Norlinah Mohamed; Azmin, Shahrul; Lim, Shen-Yang; Mohamed, Wael; Tay, Yi Wen; Martinez-Ramirez, Daniel; Rodriguez-Violante, Mayela; Reyes-Perez, Paula; Tserensodnom, Bayasgalan; Ojha, Rajeev; Anderson, Tim J.; Pitcher, Toni L.; Sanyaolu, Arinola; Okubadejo, Njideka; Ojo, Oluwadamilola; Aasly, Jan O.; Pihlstrom, Lasse; Tan, Manuela; Ur-Rehman, Shoaib; Cornejo-Olivas, Mario; Doquenia, Maria Leila; Rosales, Raymond; Vinuela, Angel; Iakovenko, Elena; Al Mubarak, Bashayer; Umair, Muhammad; Tan, Eng-King; Foo, Jia Nee; Amod, Ferzana; Carr, Jonathan; Bardien, Soraya; Jeon, Beomseok; Kim, Yun Joong; Cubo, Esther; Alvarez, Ignacio; Hoenicka, Janet; Beyer, Katrin; Perinan, Maria Teresa; Pastor, Pau; El-Sadig, Sarah; Zweier, Christiane; Paul, Krack; Lin, Chin-Hsien; Wu, Hsiu-Chuan; Kung, Pin-Jui; Wu, Ruey-Meei; Wu, Serena; Wu, Yihru; Amouri, Rim; Ben Sassi, Samia; Basak, A. Nazl; Genc, Gencer; Cakmak, Ozgur Oztop; Ertan, Sibel; Noyce, Alastair; Martinez-Carrasco, Alejandro; Schrag, Anette; Schapira, Anthony; Carroll, Camille; Bale, Claire; Grosset, Donald; Stafford, Eleanor J.; Houlden, Henry; Morris, Huw R.; Hardy, John; Mok, Kin Ying; Rizig, Mie; Wood, Nicholas; Williams, Nigel; Okunoye, Olaitan; Lewis, Patrick Alfryn; Kaiyrzhanov, Rauan; Weil, Rimona; Love, Seth; Stott, Simon; Jasaitye, Simona; Dey, Sumit; Obese, Vida; Espay, Alberto; O'Grady, Alyssa; Singleton, Andrew B.; Sobering, Andrew K.; Siddiqi, Bernadette; Casey, Bradford; Fiske, Brian; Jonas, Cabell; Cruchaga, Carlos; Pantazis, Caroline B.; Comart, Charisse; Wegel, Claire; Blauwendraat, Cornelis; Vitale, Dan; Hall, Deborah; Hernandez, Dena; Shiamim, Ejaz; Riley, Ekemini; Faghri, Faraz; Serrano, Geidy E.; Leonard, Hampton; Iwaki, Hirotaka; Chen, Honglei; Mata, Ignacio F.; Sarmiento, Ignacio Juan Keller; Williamson, Jared; Kim, Jonggeol Jeff; Jankovic, Joseph; Shulman, Joshua; Solle, Justin C.; Murphy, Kaileigh; Nuytemans, Karen; Kieburtz, Karl; Markopoulou, Katerina; Marek, Kenneth; Levine, Kristin S.; Chahine, Lana M.; Screven, Laurel; Ruffrage, Lauren; Shulman, Lisa; Marsili, Luca; Kuhl, Maggie; Dean, Marissa; Makarious, Mary B.; Koretsky, Mathew; Inca-Martinez, Miguel; Nalls, Mike A.; Louie, Naomi; Mencacci, Niccolo Emanuele; Albin, Roger; Alcalay, Roy; Walker, Ruth; Bandres-Ciga, Sara; Chowdhury, Sohini; Dumanis, Sonya; Lubbe, Steven; Xie, Tao; Foroud, Tatiana; Beach, Thomas; Sherer, Todd; Song, Yeajin; Duan Nguyen; Toan Nguyen; Atadzhanov, Masharip 分享 收藏
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Elucidating causative gene variants in hereditary Parkinson's disease in the Global Parkinson's Genetics Program (GP2) Lange, Lara; Avenali, Micol; Ellis, Melina; Illarionova, Anastasia J.; Sarmiento, Ignacio Keller; Tan, Ai-Huey; Madoev, Harutyun; Galandra, Caterina; Junker, Johanna; Roopnarain, Karisha; Solle, Justin; Wegel, Claire; Fang, Zih-Hua; Heutink, Peter R.; Kumar, Kishore; Lim, Shen-Yang; Valente, Enza Maria; Nalls, Mike; Blauwendraat, Cornelis; Singleton, Andrew; Mencacci, Niccolo; Lohmann, Katja; Klein, Christine 分享 收藏
Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease Lake, Julie; Warly Solsberg, Caroline; Kim, Jonggeol Jeffrey; Acosta-Uribe, Juliana; Makarious, Mary B.; Li, Zizheng; Levine, Kristin; Heutink, Peter; Alvarado, Chelsea X.; Vitale, Dan; Kang, Sarang; Gim, Jungsoo; Lee, Kun Ho; Pina-Escudero, Stefanie D.; Ferrucci, Luigi; Singleton, Andrew B.; Blauwendraat, Cornelis; Nalls, Mike A.; Yokoyama, Jennifer S.; Leonard, Hampton L. 分享 收藏
Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes 额颞叶变性的脑DNA甲基组学分析揭示了跨病理亚型的共享失调特征中的OTUD4 Fodder, Katherine; Murthy, Megha; Rizzu, Patrizia; Toomey, Christina E. E.; Hasan, Rahat; Humphrey, Jack; Raj, Towfique; Lunnon, Katie; Mill, Jonathan; Heutink, Peter; Lashley, Tammaryn; Bettencourt, Conceicao 分享 收藏
The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism Bressan, Elisangela; Reed, Xylena; Bansal, Vikas; Hutchins, Elizabeth; Cobb, Melanie M.; Webb, Michelle G.; Alsop, Eric; Grenn, Francis P.; Illarionova, Anastasia; Savytska, Natalia; Violich, Ivo; Broeer, Stefanie; Fernandes, Noemia; Sivakumar, Ramiyapriya; Beilina, Alexandra; Billingsley, Kimberley J.; Berghausen, Joos; Pantazis, Caroline B.; Pitz, Vanessa; Patel, Dhairya; Daida, Kensuke; Meechoovet, Bessie; Reiman, Rebecca; Courtright-Lim, Amanda; Logemann, Amber; Antone, Jerry; Barch, Mariya; Kitchen, Robert; Li, Yan; Amer Genome Ctr, Patrizia; Rizzu, Patrizia; Hernandez, Dena G.; Hjelm, Brooke E.; Nalls, Mike; Gibbs, J. Raphael; Finkbeiner, Steven; Cookson, Mark R.; Van Keuren-Jensen, Kendall; Craig, David W.; Singleton, Andrew B.; Heutink, Peter; Blauwendraat, Cornelis 分享 收藏
Mitochondrial haplogroups and cognitive progression in Parkinson's disease 线粒体单倍群与帕金森病的认知进展 Liu, Ganqiang; Ni, Chunming; Zhan, Jiamin; Li, Weimin; Luo, Junfeng; Liao, Zhixiang; Locascio, Joseph J.; Xian, Wenbiao; Chen, Ling; Pei, Zhong; Corvol, Jean-Christophe; Maple-Grodem, Jodi; Campbell, Meghan C.; Elbaz, Alexis; Lesage, Suzanne; Brice, Alexis; Hung, Albert Y.; Schwarzschild, Michael A.; Hayes, Michael T.; Wills, Anne-Marie; Ravina, Bernard; Shoulson, Ira; Taba, Pille; Koks, Sulev; Beach, Thomas G.; Cormier-Dequaire, Florence; Alves, Guido; Tysnes, Ole-Bjorn; Perlmutter, Joel S.; Heutink, Peter; van Hilten, Jacobus J.; Barker, Roger A.; Williams-Gray, Caroline H.; Scherzer, Clemens R. 分享 收藏
17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease are associated with LRRC37A/2 expression in astrocytes Bowles, Kathryn R.; Pugh, Derian A.; Liu, Yiyuan; Patel, Tulsi; Renton, Alan E.; Bandres-Ciga, Sara; Gan-Or, Ziv; Heutink, Peter; Siitonen, Ari; Bertelsen, Sarah; Cherry, Jonathan D.; Karch, Celeste M.; Frucht, Steven J.; Kopell, Brian H.; Peter, Inga; Park, Y. J.; Charney, Alexander; Raj, Towfique; Crary, John F.; Goate, A. M. 分享 收藏
Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia Miedema, Suzanne S. M.; Mol, Merel O.; Koopmans, Frank T. W.; Hondius, David C.; van Nierop, Pim; Menden, Kevin; Mestdagh, Christina F. de Veij; van Rooij, Jeroen; Ganz, Andrea B.; Paliukhovich, Iryna; Melhem, Shamiram; Li, Ka Wan; Holstege, Henne; Rizzu, Patrizia; van Kesteren, Ronald E.; van Swieten, John C.; Heutink, Peter; Smit, August B. 分享 收藏
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