Panagiotis A. Konstantinopoulos

Dana-Farber Cancer Institute

65H指数

478论文数

1.9W被引数

收录论文 103

发表时间

Personalized neoantigen-targeting cancer vaccines in ovarian cancer: a phase 1 trial 卵巢癌中个性化新抗原靶向癌症疫苗：一项1期临床试验

Nature Medicine

IF50

2026-10-14

PREAI

MacLean C. Sellars; Jessica A. Frank; Bohoon Shim; Allison Vanasse; Ruolin Liu; Cleo Forman; Chloe R. Tu; Kyohei K. Tabata; Antonia Kowelewski; Su-Chun Cheng; Catherine Song; Kan Xiong; Pia Jain; Andjela Crnjac; Haley E. Sax; Vipheaviny Chea; Wesley Lu; J. Thomas Janes; Micah Rickles-Young; Amit Sud; Savni Sarolkar; Martin Hayes; Oriol Olive; Haley Greenslade; Carrie Cibulskis; Nir Hacohen; Edward F. Fritsch; Shuqiang Li; Kenneth J. Livak; Nabihah Tayob; Elizabeth H. Stover; Carolyn Krasner; Rebecca Porter; Ursula Matulonis; Gad Getz; Giacomo Oliveira; Patrick A. Ott; Jeremy M. Simon; Viktor A. Adalsteinsson; Derin B. Keskin; Panagiotis A. Konstantinopoulos; Catherine J. Wu

Molecular characterization of NSMP endometrial cancer and its relevance for treatment NSMP子宫内膜癌的分子特征及其与治疗的相关性

Gynecologic Oncology

IF4.1

2026-09-01

PREAI

Silk, Tarik; Matulonis, Ursula A.; Konstantinopoulos, Panagiotis A.

Toward precision prognosis: Predicting recurrence-free survival in high-grade serous ovarian cancer patients using multi-time point clinical and computed tomography radiomics data 迈向精准预后：利用多时间点临床数据和计算机断层扫描影像组学数据预测高级别浆液性卵巢癌患者的无复发生存期

Gynecologic Oncology

IF4.1

2026-07-01

PREAI

Roller, Lauren; Zhou, Ningxuan; Atre, Isha; Xiong, Niya; Li, Jiafei; Cheng, Su-Chun; Liu, Natalie; Lacad, Danniele; Adjei, Michie; Matulonis, Ursula A.; Konstantinopoulos, Panagiotis A.; Liu, Joyce F.; Tayob, Nabihah; Stover, Elizabeth H.; Shinagare, Atul B.

Targeting FGFR signaling overcomes therapeutic resistance and immune evasion in oncogenic PIK3CA-driven serous-like endometrial cancer 靶向FGFR信号克服由癌基因PIK3CA驱动的浆液样子宫内膜癌的疗法抵抗和免疫逃逸

Nature Communications

IF15.7

2026-05-04

OAAI

Xin Cheng; Yadong Zhang; Changli Qian; Erica Holdridge; Guruprasad Ananda; Tao Jiang; Jing Ni; Shaozhen Xie; Hao Gu; Renlei Ji; Elena V. Ivanova; Marisa R. Nucci; Zhe Wang; Kaifu Chen; Bose Kochupurakkal; Gordon J. Freeman; Geoffrey I. Shapiro; Joyce Liu; Panagiotis A. Konstantinopoulos; Ursula Matulonis; Jean J. Zhao

Mirvetuximab soravtansine plus pembrolizumab in recurrent folate receptor alpha-positive uterine serous carcinoma: a phase II trial Mirvetuximab soravtansine 联合 pembrolizumab 治疗 Folate 受体 α 阳性的复发性子宫浆液性癌：一项 II 期临床试验

Nature Communications

IF15.7

2026-03-26

OAAI

Rebecca L. Porter; Yinglu Zhou; Nebiyat Eskndir; Martin Hayes; Madeline Polak; Elizabeth K. Lee; Carolyn Krasner; Susana Campos; Alexi A. Wright; Joyce F. Liu; Elizabeth H. Stover; Hannah Sawyer; Niya Xiong; Kathleen L. Pfaff; Scott J. Rodig; Nabihah Tayob; Susan Zweizig; Veena John; Jennifer Veneris; Ursula A. Matulonis; Panagiotis A. Konstantinopoulos

Letrozole, abemaciclib and metformin in endometrial cancer: a non-randomized phase 2 trial 来曲唑、阿贝西利和二甲双胍在子宫内膜癌中的应用：一项非随机性Ⅱ期临床试验

Nature Communications

IF15.7

2025-12-03

OAAI

Panagiotis A. Konstantinopoulos; Ningxuan Zhou; Richard T. Penson; Tien V. Le; Susana Campos; Carolyn Krasner; Alexi A. Wright; Rebecca Porter; Neil Horowitz; Sara Bouberhan; Joyce F. Liu; Sarah Hindenach; Hannah Sawyer; Lani Koppermann; Martin Hayes; Madeline Polak; Meghan Shea; Page Widick; Su-Chun Cheng; Cesar Castro; Jan H. Beumer; Ursula A. Matulonis; Elizabeth K. Lee

A phase I clinical trial of radiation therapy, durvalumab and tremelimumab in recurrent gynecologic cancer 一项关于放射治疗、durvalumab和tremelimumab在复发性妇科癌症中的I期临床试验

gynecologic oncology

IF4.1

2025-06-01

PREAI

Fitzgerald, Kelly J.; Konstantinopoulos, Panagiotis; Matulonis, Ursula; Liu, Joyce; Horowitz, Neil; Lee, Elizabeth; Kolin, David L.; Lee, Larissa; King, Martin

Role of adjuvant radiotherapy modality on clinical outcomes for early-stage uterine carcinosarcoma 早期子宫癌肉瘤辅助放疗模式对临床结局的影响

gynecologic oncology

IF4.1

2025-04-01

PREAI

Tyan, Kevin; Liu, Kevin X.; Smart, Alicia C.; Feltmate, Colleen M.; Horowi, Neil S.; Muto, Michael G.; Worley Jr, Michael J.; Elias, Kevin M.; Liu, Joyce F.; Wright, Alexi A.; Konstantinopoulos, Panagiotis A.; Campos, Susana M.; Matulonis, Ursula A.; Franco, Idalid; Le, Larissa J.; King, Martin T.; Dyer, M. Aiven

53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer

NATURE COMMUNICATIONS

IF15.7

2024-08-06

OAAI

Sun, Yajie; Patterson-Fortin, Jeffrey; Han, Sen; Li, Zhe; Nowicka, Zuzanna; Hirohashi, Yuna; Kilgas, Susan; Yi, Jae Kyo; Spektor, Alexander; Fendler, Wojciech; Konstantinopoulos, Panagiotis A.; Chowdhury, Dipanjan

A phase 2, two-stage study of mirvetuximab soravtansine (IMGN853) in combination with pembrolizumab in patients with microsatellite stable (MSS) recurrent or persistent endometrial cancer

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Porter, Rebecca L.; Xiong, Niya; Tayob, Nabihah; Polak, Madeline; Sawyer, Hannah; Hayes, Martin; Gardner, Jeanette; Campos, Susana; Horowitz, Neil; Krasner, Carolyn; Lee, Elizabeth K.; Liu, Joyce F.; Stover, Elizabeth H.; Veneris, Jennifer; Wright, Alexi A.; Matulonis, Ursula A.; Konstantinopoulos, Panagiotis

Co-clinical endometrial cancer (EC) patient-derived organoids (PDO) to assess functional effects of replication stress (RS)-targeting agents

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Ivanova, Elena; Saldanha, Aisha L.; Roychoudhury, Shrabasti; Kochupurakkal, Bose; Zlota, Ari P.; Padrick, Clare E.; Vo, Ha V.; Greenberg, Eli K.; Sawyer, Hannah; Feeney, Carina; Qi, Courtney H.; Narayan, Swati; Curtis, Jennifer D.; Tayob, Nabihah; Nucci, Marisa R.; Konstantinopoulos, Panagiotis; Chowdhury, Dipanjan; Shapiro, Geoffrey; Paweletz, Cloud P.; Matulonis, Ursula A.; Liu, Joyce F.

Detection and dynamic monitoring of clonal hematopoiesis mutations in women receiving systemic therapies for high grade serous ovarian carcinoma

CANCER RESEARCH

IF16.6

2024-03-04

PREAI

Porter, Rebecca L.; Qi, Courtney H.; Feeney, Carina; Narayan, Swati; Tayob, Nabihah; Curtis, Jennifer; Campos, Susana; Horowitz, Neil; Krasner, Carolyn; Lee, Elizabeth; Stover, Elizabeth; Wright, Alexi; Weeks, Lachelle; Gibson, Christopher; Liu, Joyce; Konstantinopoulos, Panagiotis; Lindsley, Robert C.; Matulonis, Ursula

Personalized targeted circulating tumor DNA (ctDNA) and T-cell responses after combined neoantigen vaccine and immune checkpoint blockade in ovarian cancer

CANCER RESEARCH

IF16.6

2024-03-04

PREAI

Sellars, MacLean C.; Porter, Rebecca; Liu, Ruolin; Howard, Alexis A.; Xiong, Kan; Crnjac, Andela; Tayob, Nabihah; Keskin, Derin; Adalsteinsson, Vicktor; Wu, Catherine; Konstantinopoulos, Panagiotis

53BP1 loss mediated PARP inhibitor resistance in BRCA1-deficient pancreatic cancer is overcome with immune checkpoint blockade

CANCER RESEARCH

IF16.6

2024-01-09

PREAI

Patterson-Fortin, Jeffrey; Sun, Yajie; Han, Sen; Li, Zhe; Nowicka, Zuzanna; Hirohashi, Yuna; Kilgas, Susan; Yi, Jae Kyo; Spektor, Alexander; Fendler, Wojciech; Konstantinopoulos, Panagiotis; D'Andrea, Alan D.; Chowdhury, Dipanjan

A phase 1 study of DS-8201a in combination with olaparib in HER2-expressing malignancies (CTEP #10355): Results of module 1 dose escalation

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-01

PREAI

Lee, Elizabeth K.; Hendrickson, Andrea E. Wahner; Colon-Otero, Gerardo; Pickett, Cheryl A.; Xiong, Niya; Cheng, Su-Chun; Polak, Madeline; Sawyer, Hannah; Hayes, Martin; Matulonis, Ursula A.; Shapiro, Geoffrey I.; Konstantinopoulos, Panagiotis A.

Transforming ovarian cancer care by targeting minimal residual disease 通过针对最小残留疾病转变卵巢癌护理

MED

IF11.8

2023-11-01

OAAI

Jazaeri, Amir A.; Grisham, Rachel; Knisely, Anne; Spranger, Stefani; Zamarin, Dmitriy; Hillman, R. Tyler; Lawson, Barrett C.; Burns, Kathleen H.; Lee, Sanghoon; Westin, Shannon N.; Moiso, Enrico; Williams, Marc J.; Bardhan, Neelkanth M.; Pisanic, Thomas; Matulonis, Ursula; Weigelt, Britta; Shih, Ieming; Konstantinopoulos, Panagiotis A.; Gaillard, Stephanie; Wang, Linghua; Aghajanian, Carol; D'Andrea, Alan D.; Hammond, Paula; Shah, Sohrab; Wucherpfennig, Kai W.; Lu, Karen H.

Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs DYNLL1-MRE11复合物的动力学调节DNA末端切除和Shieldin向dsb的募集

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-09-11

OAAI

Swift, Michelle L.; Zhou, Rui; Syed, Aleem; Moreau, Lisa A.; Tomasik, Bartlomiej; Tainer, John A.; Konstantinopoulos, Panagiotis A.; D'Andrea, Alan D.; He, Yizhou Joseph; Chowdhury, Dipanjan

Clinical and translational advances in ovarian cancer therapy

NATURE CANCER

IF28.5

2023-08-31

PREAI

Konstantinopoulos, Panagiotis A.; Matulonis, Ursula A.

ARTISTRY-7: Phase III trial of nemvaleukin alfa plus pembrolizumab vs chemotherapy for platinum-resistant ovarian cancer ARTISTRY-7: nemvaleukin alfa联合pembrolizumab与化疗治疗铂类耐药卵巢癌的III期试验

FUTURE ONCOLOGY

IF2.6

2023-06-19

OAAI

Herzog, Thomas J.; Hays, John L.; Barlin, Joyce N.; Buscema, Joseph; Cloven, Noelle G.; Kong, Lynn R.; Tyagi, Nidhi Kumar; Lanneau, Grainger S.; Long, Beverly J.; Marsh, Robert L.; Seward, Shelly M.; Starks, David C.; Welch, Stephen; Moore, Kathleen N.; Konstantinopoulos, Panagiotis A.; Gilbert, Lucy; Monk, Bradley J.; O'Malley, David M.; Chen, Xiwei; Dalal, Rita; Coleman, Robert L.; Sehouli, Jalid

Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer

NPJ PRECISION ONCOLOGY

IF8

2022-12-29

OAAI

Perez-Villatoro, Fernando; Oikkonen, Jaana; Casado, Julia; Chernenko, Anastasiya; Gulhan, Doga C.; Tumiati, Manuela; Li, Yilin; Lavikka, Kari; Hietanen, Sakari; Hynninen, Johanna; Haltia, Ulla-Maija; Tyrmi, Jaakko S.; Laivuori, Hannele; Konstantinopoulos, Panagiotis A.; Hautaniemi, Sampsa; Kauppi, Liisa; Farkkila, Anniina

研究方向