未登录 Phosphorylation of SNAP-25 at Ser187 is enhanced following its cleavage by Botulinum Neurotoxin Serotype A, promoting the dominant-negative effect of the resulting fragment BoNT/A介导的SNAP-25切割后，SNAP-25在Ser187位的磷酸化水平升高，并促进切割后产生的片段发挥显性负效应。 Koc, Dilara; Ezgin, Sena; Kavakli, Ebru; Kota, Krishna P.; Sen, Edanur; Mahone, Christopher; Palko, Mary Ellen; Cazares, Lisa H.; Can, Tolga; Tessarollo, Lino; Bavari, Sina; Marion, Antoine; Kiris, Erkan 分享 收藏
Recombinant chimeric horsepox virus (TNX-801) is attenuated relative to vaccinia virus strains in both in vitro and in vivo models Trefry, Stephanie V.; Awasthi, Mayanka; Raney, Christy N.; Cregger, Amy L.; Gonzales, Chase A.; Layton, Brittney L.; Enamorado, Robert N.; Martinez, Nelson A.; Gohegan, Deborah S.; Masoud-Bahnamiri, Masoudeh; Cho, Jennifer Y.; Myscofski, Dawn M.; Moulaei, Tinoush; Ziolkowska, Natasza E.; Goebel, Scott J.; Lederman, Seth; Bavari, Sina; Nasar, Farooq 分享 收藏
A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques Zumbrun, Elizabeth E.; Garvey, Carly B.; Wells, Jay B.; Lynn, Ginger C.; Van Tongeren, Sean A.; Steffens, Jesse T.; Wetzel, Kelly S.; Wetzel, Darrell L.; Esham, Heather L.; Garza, Nicole L.; Lee, Eric D.; Scruggs, Jennifer L.; Rossi, Franco D.; Brown, Elizabeth S.; Weidner, Jessica M.; Gomba, Laura M.; O'Brien, Kristan A.; Jay, Alexandra N.; Zeng, Xiankun; Akers, Kristen S.; Kallgren, Paul A.; Englund, Ethan; Meinig, J. Matthew; Kugelman, Jeffrey R.; Moore, Joshua L.; Bloomfield, Holly A.; Norris, Sarah L.; Bryan, Tameka; Scheuerell, Christie H.; Walters, Jesse; Mollova, Nevena; Blair, Christiana; Babusis, Darius; Cihlar, Tomas; Porter, Danielle P.; Singh, Bali; Hedskog, Charlotte; Bavari, Sina; Warren, Travis K.; Bannister, Roy 分享 收藏
High-Throughput Screening Assay for Convalescent Sera in COVID-19: Efficacy, Donor Selection, and Variant Neutralization Kota, Krishna P.; Trakht, Ilya; Kalantarov, Gavreel; Ordonez, David; Wei, Jiayi; Trefry, Stephanie; Bavari, Evia; Richardson, Jenny; Zamani, Rouzbeh; Raney, Christy; Nasar, Farooq; Daugherty, Bruce; Lederman, Seth; Bavari, Sina 分享 收藏
Immunogenicity and Efficacy of TNX-1800, A Live Virus Recombinant Poxvirus Vaccine Candidate, against SARS-CoV-2 Challenge in Nonhuman Primates Awasthi, Mayanka; Macaluso, Anthony; Myscofski, Dawn; Prigge, Jon; Koide, Fusataka; Noyce, Ryan S.; Fogarty, Siobhan; Stillwell, Helen; Goebel, Scott J.; Daugherty, Bruce; Nasar, Farooq; Bavari, Sina; Lederman, Seth 分享 收藏
Immunogenicity and Tolerability of a SARS-CoV-2 TNX-1800, a Live Recombinant Poxvirus Vaccine Candidate, in Syrian Hamsters and New Zealand White Rabbits Awasthi, Mayanka; Macaluso, Anthony; Goebel, Scott J.; Luea, Erin; Noyce, Ryan S.; Nasar, Farooq; Daugherty, Bruce; Bavari, Sina; Lederman, Seth 分享 收藏
Eastern equine encephalitis virus rapidly infects and disseminates in the brain and spinal cord of cynomolgus macaques following aerosol challenge Williams, Janice A.; Long, Simon Y.; Zeng, Xiankun; Kuehl, Kathleen; Babka, April M.; Davis, Neil M.; Liu, Jun; Trefry, John C.; Daye, Sharon; Facemire, Paul R.; Iversen, Patrick L.; Bavari, Sina; Pitt, Margaret L.; Nasar, Farooq 分享 收藏
A Novel Toll-Like Receptor 2 Agonist Protects Mice in a Prophylactic Treatment Model Against Challenge With Bacillus anthracis Chiang, Chih-Yuan; Lane, Douglas J.; Zou, Yefen; Hoffman, Tim; Pan, Jianfeng; Hampton, Janice; Maginnis, Jillian; Nayak, Bishnu P.; D'Oro, Ugo; Valiante, Nicholas; Miller, Andrew T.; Cooke, Michael; Wu, Tom; Bavari, Sina; Panchal, Rekha G. 分享 收藏
Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activation of autophagy Alem, Farhang; Olanrewaju, Adeyemi A.; Omole, Samson; Hobbs, Heather E.; Ahsan, Noor; Matulis, Graham; Brantner, Christine A.; Zhou, Weidong; Petricoin, Emanuel F.; Liotta, Lance A.; Caputi, Massimo; Bavari, Sina; Wu, Yuntao; Kashanchi, Fatah; Hakami, Ramin M. 分享 收藏
Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus Warren, Travis K.; Kane, Christopher D.; Wells, Jay; Stuthman, Kelly S.; Van Tongeren, Sean A.; Garza, Nicole L.; Donnelly, Ginger; Steffens, Jesse; Gomba, Laura; Weidner, Jessica M.; Norris, Sarah; Zeng, Xiankun; Bannister, Roy; Cihlar, Tomas; Bavari, Sina; Porter, Danielle P.; Iversen, Patrick L. 分享 收藏
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The utilization of advance telemetry to investigate critical physiological parameters including electroencephalography in cynomolgus macaques following aerosol challenge with eastern equine encephalitis virus Trefry, John C.; Rossi, Franco D.; Accardi, Michael V.; Dorsey, Brandi L.; Sprague, Thomas R.; Wollen-Roberts, Suzanne E.; Shamblin, Joshua D.; Kimmel, Adrienne E.; Glass, Pamela J.; Miller, Lynn J.; Burke, Crystal W.; Cardile, Anthony P.; Smith, Darci R.; Bavari, Sina; Authier, Simon; Pratt, William D.; Pitt, Margaret L.; Nasar, Farooq 分享 收藏
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Intensive Care Unit-Like Care of Nonhuman Primates with Ebola Virus Disease Blair, Paul W.; Kortepeter, Mark G.; Downey, Lydia G.; Madar, Cristian S.; Downs, Isaac L.; Martins, Karen A.; Rossi, Franco; Williams, Janice A.; Madar, Annie; Schellhase, Christopher W.; Bearss, Jeremy J.; Zeng, Xiankun; Bavari, Sina; Soloveva, Veronica; Wells, Jay B.; Stuthman, Kelly S.; Garza, Nicole L.; Vantongeren, Sean A.; Donnelly, Ginger C.; Steffens, Jesse; Kalapaca, Jennifer; Wiseman, Perry; Henry, Joseph; Marko, Shannon; Chappell, Mark; Lugo-Roman, Luis; Ramos-Rivera, Elliot; Hofer, Christian; Blue, Eugene; Moore, Joshua; Fiallos, Jimmy; Wetzel, Darrel; Pratt, William D.; Unangst, Tami; Miller, Adele; Sola, James J.; Reisler, Ronald B.; Cardile, Anthony P. 分享 收藏
Approach to Cataract Surgery in an Ebola Virus Disease Survivor with Prior Ocular Viral Persistence Wells, Jill R.; Crozier, Ian; Kraft, Colleen S.; Sexton, Mary Elizabeth; Hill, Charles E.; Ribner, Bruce S.; Bavari, Sina; Palacios, Gustavo; Pearce, William A.; Van Gelder, Russell; Grossniklaus, Hans; Cazares, Lisa; Zeng, Xiankung; Shantha, Jessica G.; Yeh, Steven 分享 收藏
Modeling mosquito-borne and sexual transmission of Zika virus in an enzootic host, the African green monkey Haddow, Andrew D.; Perez-Sautu, Unai; Wiley, Michael R.; Miller, Lynn J.; Kimmel, Adrienne E.; Principe, Lucia M.; Wollen-Roberts, Suzanne E.; Shamblin, Joshua D.; Valdez, Stephanie M.; Cazares, Lisa H.; Pratt, William D.; Rossi, Franco D.; Lugo-Roman, Luis; Bavari, Sina; Palacios, Gustavo F.; Nalca, Aysegul; Nasar, Farooq; Pitt, M. Louise M. 分享 收藏
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Remdesivir (GS-5734) Is Efficacious in Cynomolgus Macaques Infected With Marburg Virus Porter, Danielle P.; Weidner, Jessica M.; Gomba, Laura; Bannister, Roy; Blair, Christiana; Jordan, Robert; Wells, Jay; Wetzel, Kelly; Garza, Nicole; Van Tongeren, Sean; Donnelly, Ginger; Steffens, Jesse; Moreau, Alicia; Bearss, Jeremy; Lee, Eric; Bavari, Sina; Cihlar, Tomas; Warren, Travis K. 分享 收藏
Characterization of Ebola Virus Disease (EVD) in Rhesus Monkeys for Development of EVD Therapeutics Warren, Travis; Zumbrun, Elizabeth; Weidner, Jessica M.; Gomba, Laura; Rossi, Franco; Bannister, Roy; Tarrant, Jacqueline; Reed, Matthew; Lee, Eric; Raymond, Jo Lynne; Wells, Jay; Shamblin, Joshua; Wetzel, Kelly; Donnelly, Ginger; Van Tongeren, Sean; Lackemeyer, Nicole; Steffens, Jesse; Kimmel, Adrienne; Garvey, Carly; Bloomfield, Holly; Blair, Christiana; Singh, Bali; Bavari, Sina; Cihlar, Tomas; Porter, Danielle 分享 收藏
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