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R

Ryan J. Sullivan

Harvard Medical School
H指数:90
被引数:4.4万

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Bispecific dual T cell agonist invikafusp alfa in solid tumors: the phase 1/2 START-001 trial

双特异性双T细胞激动剂invikafusp alfa在实体瘤中的研究：第1/2期START-001试验

Nature Medicine
IF50
2026-10-230
PRE
Ryan J. Sullivan; Nicholas P. Tschernia; Claire F. Friedman; Mercedes Herrera; Guru P. Sonpavde; Kai He; Antoine Italiano; Aurélien Marabelle; Matthieu Roulleaux-Dugage; François-Xavier Danlos; Elena Garralda Cabanas; Alberto Hernando-Calvo; Manuel Pedregal; Aparna Parikh; Gopakumar Iyer; Ahmed Zakari; E. John Wherry; Jeffrey Schlom; Renee N. Donahue; Shannon McCue; Sharon Cross; Karunya Srinivasan; Lisa Benincosa; Madan Katragadda; Zhenming Shun; Kevin Chin; Zhen Su; Ke Liu; Lillian L. Siu; James L. Gulley
An anti-PMEL antibody−drug conjugate with a Gq/11 inhibitor payload in GNAQ/GNA11-mutant melanomas: a phase 1 trial

在GNAQ/GNA11突变型黑色素瘤中具有Gq/11抑制剂载荷的抗PMEL抗体−药物偶联物：一项1期临床试验

Nature Medicine
IF50
2026-07-130
OA
Matteo S. Carlino; Ellen Kapiteijn; Sophie Piperno-Neumann; Ryan J. Sullivan; Richard Carvajal; Reinhard Dummer; Tanja Gromke; Jessica C. Hassel; Damien Kee; Egle Ramelyte; Alexander N. Shoushtari; Alexander Z. Wei; Alexander Enk; Eleanor E. Handel; Kamaneh Montazeri; Jorge Ramon-Patino; Heike Richly; Manuel Rodrigues; Shahneen Sandhu; James Smithy; Frank M. Speetjens; Pedro Milanez-Almeida; Anwesha Chaudhury; Keith Hoffmaster; Mary Ising; Javier A. Otero; Thiruvamoor RamKumar; Aimee Reynolds; Sherif Sharaby; Lillian Werner; Padmaja Yerramilli-Rao; Emiliano Calvo
Personalized targeting of BCL2 family proteins overcomes acquired resistance to BRAF-MEK inhibitors in preclinical melanoma

针对BCL2家族蛋白的个性化靶向策略可克服BRAF-MEK抑制剂在黑色素瘤模型中的获得性耐药

Nature Communications
IF15.7
2026-06-260
OAAI
Vashisht Gopal Y.N.; Evelyn de Groot; Kaley Loftin; Barbara Knighton; Debora Ledesma; Courtney Hudgens; Diana Shamsutdinova; Mehboob Ali; Zhenlin Ju; Min Xiao; Toshitha Kannan; Gregory Fontenot; Michael S. Nakazawa; Monzy Thomas; Khalida Wani; Clifford Stephan; Phyu P. Aung; Lawrence N. Kwong; Janos Roszik; Rehan Akbani; Andrew Kossenkov; Vito W. Rebecca; Ryan J. Sullivan; Meenhard Herlyn; Michael A. Davies
Multimodal blood based proteomic profiling reveals insights into mechanisms of immunotherapy resistance

多模态血液蛋白质组学分析揭示了免疫治疗耐药机制的见解

Nature Communications
IF15.7
2026-06-240
OA
Samuel J. Wright; Izabella Zamora; Milan Parikh; Deepika Yeramosu; Marijana Rucevic; Moshe Sade-Feldman; Thomas J. LaSalle; Emily M. Blaum; Baolin Liu; Lynn Bi; Sarah Kang; Steven M. Blum; Ngan Nguyen; Jamey Guess; Amrita Kar; Alexis M. Schneider; David Lieb; Elliot Woods; William Michaud; Aleigha R. Lawless; Tatyana Sharova; Sonia Cohen; Gyulnara Kasumova; Michelle S. Kim; Li-Chun Cheng; Alexandra-Chloé Villani; Ryan J. Park; Russell W. Jenkins; Samuel J. Klempner; Ryan J. Sullivan; Keith T. Flaherty; Nir Hacohen; Arnav Mehta; Genevieve M. Boland
Integrating multimodal management and molecular profiling in a patient with BRAF V600E–positive melanoma and brain metastases

整合多模态管理与分子分型在BRAF V600E阳性黑色素瘤伴脑转移患者中的应用

ca: a cancer journal for clinicians
IF0
2026-03-260
OAAI
David Gritsch MD, PhD; Riley M. Fadden CNP; Maura K. Mahar CNP; Melin J. Khandsekar MD, PhD; Kevin S. Oh MD. MBA; Daniel P. Cahil III MD, PhD; Gavin P. Dunn MD, PhD; Ryan J. Sullivan MD; Priscilla K. Brastianos MD
Understanding tumor-immune-stromal dynamics driving response and resistance to immune checkpoint blockade in melanoma
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Tarantino, Giuseppe; He, Yiwen; Solanky, Priyanka; Cui, Xinyu; Pfaff, Kathleen; Thorner, Aaron R.; Blosser, Timothy; Boblitt, Elliot; Frangieh, Allison; Aprati, Tyler; Zhang, Boyang; Chen, Jiajia; Faulkner, Hannah Mae; Lawless, Aleigha; Manos, Michael; Helvie, Karla; Sharova, Tatyana; Frederick, Dennie; Krishna, Sachi; Mangum, Chanell; Abbondanza, Domenic; Mccann, Cai; Johnson, Bruce; Shalek, Alex K.; Van Allen, Eliezer; Zhuang, Xiaowei; Sullivan, Ryan; Engelhardt, Barbara; Farhi, Sami; Rodig, Scott; Hodi, F. Stephen; Boland, Genevieve M.; Liu, David
NASCENT CLINICAL EXPERIENCE WITH RADIOTHERAPEUTIC MANAGEMENT OF MELANOMA BRAIN METASTASES IN PATIENTS TREATED WITH TUMOR-INFILTRATING LYMPHOCYTE (TIL) THERAPY

早期临床经验：肿瘤浸润淋巴细胞（TIL）疗法治疗患者中，放射性疗法管理黑色素瘤脑转移的应用

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Choudhury, Abrar; Lawrence, Donald; Frigault, Matthew; Cohen, Sonia; Mooradian, Meghan; Sullivan, Ryan; Khandekar, Melin; Oh, Kevin; Brastianos, Priscilla; Shih, Helen; Haugh, Alexandra; Marciscano, Ariel
Concurrent local therapy extends clinical benefit of tebentafusp in metastatic uveal melanoma patients

联合局部疗法可延长tebentafusp在转移性眼葡萄膜黑色素瘤患者中的临床获益

ONCOLOGIST
IF4.2
2025-10-010
OAAI
Lim, Tristan L.; Montazeri, Kamaneh; Wehrenberg-Klee, Eric; Desilets, Antoine; Seedor, Rino; Orloff, Marlana; Sato, Takami; Caplan, Michael; El-Ashmawy, Mariam; Izar, Benjamin; Khan, Shaheer; Mehmi, Inderjit; Lawless, Aleigha; Hong, Theodore S.; Hamid, Omid; Carvajal, Richard D.; Shoushtari, Alexander; Sullivan, Ryan J.
B NASCENT CLINICAL EXPERIENCE WITH RADIOTHERAPEUTIC MANAGEMENT OF MELANOMA BRAIN METASTASES IN PATIENTS TREATED WITH TUMOR-INFILTRATING LYMPHOCYTE (TIL) THERAPY

B 新的临床经验：使用放射治疗管理接受肿瘤浸润淋巴细胞（TIL）疗法患者的黑色素瘤脑转移

NEURO-ONCOLOGY
IF13.4
2025-10-010
OAAI
Choudhury, A.; Lawrence, D. P.; Frigault, M. J.; Cohen, S.; Mooradian, M. J.; Sullivan, R. J.; Khandekar, M. J.; Oh, K. S.; Brastianos, P.; Shih, H. A.; Haugh, A. M.; Marciscano, A. E.
Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma

成熟和迁移的树突状细胞促进免疫浸润以及对转移性黑素瘤中抗PD-1检查点阻断的应答

Nature Communications
IF15.7
2025-09-010
OAAI
Jiekun Yang; Cassia Wang; Doris Fu; Li-Lun Ho; Kyriakitsa Galani; Lee Chen; Jose Gonzalez; Jolene Fu; Amy Y. Huang; Dennie T. Frederick; Liang He; Mukta Asnani; Rahul Tacke; Emily J. Robitschek; Sandeep K. Yadav; Wentao Deng; Kelly P. Burke; Tatyana Sharova; Ryan J. Sullivan; Sarah Weiss; Kunal Rai; David Liu; Genevieve M. Boland; Manolis Kellis
Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants

通过靶向CD38克服人类肿瘤移植组织对免疫治疗的抵抗

Cell Reports Medicine
IF10.6
2025-06-270
OAAI
Or-Yam Revach; Angelina M. Cicerchia; Ofir Shorer; Claire A. Palin; Boryana Petrova; Seth Anderson; Baolin Liu; Joshua Park; Lee Chen; Arnav Mehta; Samuel J. Wright; Niamh McNamee; Aya Tal-Mason; Giulia Cattaneo; Payal Tiwari; Hongyan Xie; Johanna M. Sweere; Li-Chun Cheng; Natalia Sigal; Elizabeth Enrico; Marisa Miljkovic; Shane A. Evans; Ngan Nguyen; Mark E. Whidden; Ramji Srinivasan; Matthew H. Spitzer; Yi Sun; Tatyana Sharova; Aleigha R. Lawless; William A. Michaud; Martin Q. Rasmussen; Jacy Fang; Jeannette R. Brook; Feng Chen; Xinhui Wang; Cristina R. Ferrone; Donald P. Lawrence; Ryan J. Sullivan; David Liu; Uma M. Sachdeva; Debattama R. Sen; Keith T. Flaherty; Robert T. Manguso; Lloyd Bod; Manolis Kellis; Genevieve M. Boland; Keren Yizhak; Jiekun Yang; Naama Kanarek; Moshe Sade-Feldman; Nir Hacohen; Russell W. Jenkins
Inherited mitochondrial genetics as a predictor of immune checkpoint inhibition efficacy in melanoma

Monson, K.R.; Ferguson, R.; Handzlik, J.E.; Morales, L.; Xiong, J.; Chat, V.; Dagayev, S.; Khodadadi-Jamayran, A.; Simpson, D.; Kazlow, E.; 等. 继承的线粒体遗传学作为预测黑色素瘤免疫检查点抑制疗效的指标。Nat. Med. 2025, 31, 2385–2396. [Google Scholar] [CrossRef]

Nature Medicine
IF50
2025-06-050
OAAI
Kelsey R. Monson; Robert Ferguson; Joanna E. Handzlik; Leah Morales; Jiahan Xiong; Vylyny Chat; Sasha Dagayev; Alireza Khodadadi-Jamayran; Danny Simpson; Esther Kazlow; Anabelle Bunis; Chaitra Sreenivasaiah; Milad Ibrahim; Iryna Voloshyna; Wouter Ouwerkerk; Rosalie M. Luiten; Mariaelena Capone; Gabriele Madonna; Yuting Lu; Yongzhao Shao; Anna Pavlick; Michelle Krogsgaard; Janice Mehnert; Hao Tang; Sonia Dolfi; Daniel Tenney; John B. A. G. Haanen; Thomas F. Gajewski; F. Stephen Hodi; Keith T. Flaherty; Kasey Couts; William Robinson; Igor Puzanov; Marc S. Ernstoff; Osama Rahma; Michael Postow; Ryan J. Sullivan; Jason J. Luke; Paolo A. Ascierto; Iman Osman; Tomas Kirchhoff
Characterizing Chronic Cutaneous Immune-Related Adverse Events Following Immune Checkpoint Inhibitors

评估免疫检查点抑制剂治疗后慢性皮肤免疫相关不良事件的特征

JAMA DERMATOLOGY
IF11
2025-05-010
PRE
Fletcher, Kylie A.; Goodman, Rachel S.; Lawless, Aleigha; Woodford, Rachel; Fa'ak, Faisal; Tipirneni, Asha; Patrinely, J. Randall; Yeoh, Hui Ling; Rapisuwon, Suthee; Haydon, Andrew; Osman, Iman; Mehnert, Janice M.; Long, Georgina V.; Sullivan, Ryan J.; Carlino, Matteo S.; Menzies, Alexander M.; Dewan, Anna K.; Johnson, Douglas B.
Cutaneous melanoma

皮肤黑色素瘤

Nature Reviews Disease Primers
IF60.6
2025-04-030
PRE
Tasdogan, Alpaslan; Sullivan, Ryan J.; Katalinic, Alexander; Lebbe, Celeste; Whitaker, Dagmar; Puig, Susana; van de Poll-Franse, Lonneke V.; Massi, Daniela; Schadendorf, Dirk

研究方向

暂未获取到该数据
K
Keith T. Flaherty
H 指数:146论文数:1,736被引数:12.1万
D
Donald P. Lawrence
H 指数:67论文数:425被引数:2.9万
G
Genevieve M. Boland
H 指数:69论文数:770被引数:2.8万
K
Kerry L. Reynolds
H 指数:54论文数:334被引数:1.3万
D
Dennie T. Frederick
H 指数:65论文数:533被引数:3.0万
D
Douglas B. Johnson
H 指数:100论文数:744被引数:4.6万
G
Georgina V. Long
H 指数:169论文数:1,833被引数:17.2万
A
Alexander M. Menzies
H 指数:85论文数:759被引数:3.1万
P
Paolo A. Ascierto
H 指数:126论文数:1,662被引数:10.8万
J
Justine V. Cohen
H 指数:43论文数:243被引数:1.1万