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Humoral Immunogenicity of mRNA-1345 RSV Vaccine in Older Adults Goswami, Jaya; Baqui, Abdullah H.; Doreski, Pablo A.; Marc, Gonzalo Perez; Jimenez, Gilberto; Ahmed, Salahuddin; Zaman, Khalequz; Duncan, Christopher J. A.; Ujiie, Mugen; Ramet, Mika; Perez-Breva, Lina; Lan, Lan; Du, Jiejun; Kapoor, Archana; Mehta, Shraddah; Tomassini, Joanne E.; Huang, Wenmei; Zhou, Honghong; Stoszek, Sonia K.; Priddy, Frances; Lin, Nina; Le Cam, Nancy; Shaw, Christine A.; Slobod, Karen; Wilson, Eleanor; Miller, Jacqueline M.; Das, Rituparna 分享 收藏
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Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis 截断NFKB1变体会导致NLRP3炎性体激活和I型干扰素信号传导相结合，并易患坏死性筋膜炎 Nurmi, Katariina; Silventoinen, Kristiina; Keskitalo, Salla; Rajamaki, Kristiina; Kouri, Vesa-Petteri; Kinnunen, Matias; Jalil, Sami; Maldonado, Rocio; Wartiovaara, Kirmo; Nievas, Elma Ines; Denita-Juarez, Silvina Paola; Duncan, Christopher J. A.; Kuismin, Outi; Saarela, Janna; Romo, Inka; Martelius, Timi; Parantainen, Jukka; Beklen, Arzu; Bilicka, Marcelina; Matikainen, Sampsa; Nordstroem, Dan C.; Kaustio, Meri; Wartiovaara-Kautto, Ulla; Kilpivaara, Outi; Klein, Christoph; Hauck, Fabian; Jahkola, Tiina; Hautala, Timo; Varjosalo, Markku; Barreto, Goncalo; Seppanen, Mikko R. J.; Eklund, Kari K. 分享 收藏
Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults 基于mRNA的RSV PreF疫苗在老年人中的功效和安全性 Wilson, Eleanor; Goswami, Jaya; Baqui, Abdullah H.; Doreski, Pablo A.; Perez-Marc, Gonzalo; Zaman, Khalequ; Monroy, Jorge; Duncan, Christopher J. A.; Ujiie, Mugen; Raemet, Mika; Perez-Breva, Lina; Falsey, Ann R.; Walsh, Edward E.; Dhar, Rakesh; Wilson, Lauren; Du, Jiejun; Ghaswalla, Parinaz; Kapoor, Archana; Lan, Lan; Mehta, Shraddha; Mithani, Runa; Panozzo, Catherine A.; Simorellis, Alana K.; Kuter, Barbara J.; Schoedel, Florian; Huang, Wenmei; Reuter, Caroline; Slobod, Karen; Stoszek, Sonia K.; Shaw, Christine A.; Miller, Jacqueline M.; Das, Rituparna; Chen, Grace L. 分享 收藏
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CD4+and CD8+T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study CD4和CD8 T细胞和抗体与预防Delta疫苗突破性感染相关: PITCH研究中的巢式病例对照研究 Neale, Isabel; Ali, Mohammad; Kronsteiner, Barbara; Longet, Stephanie; Abraham, Priyanka; Deeks, Alexandra S.; Brown, Anthony; Moore, Shona C.; Stafford, Lizzie; Dobson, Susan L.; Plowright, Megan; Newman, Thomas A. H.; Wu, Mary Y.; Carr, Edward J.; Beale, Rupert; Otter, Ashley D.; Hopkins, Susan; Hall, Victoria; Tomic, Adriana; Payne, Rebecca P.; Barnes, Eleanor; Richter, Alex; Duncan, Christopher J. A.; Turtle, Lance; de Silva, Thushan I.; Carroll, Miles; Lambe, Teresa; Klenerman, Paul; Dunachie, Susanna; PITCH Consortium 分享 收藏
Omicron BA.1-containing mRNA-1273 boosters compared with the original COVID-19 vaccine in the UK: a randomised, observer-blind, active-controlled trial Lee, Ivan; Cosgrove, Catherine A.; Moore, Patrick; Bethune, Claire; Nally, Rhiannon; Bula, Marcin; Kalra, Philip A.; Clark, Rebecca; Dargan, Paul, I; Boffito, Marta; Sheridan, Ray; Moran, Ed; Darton, Thomas C.; Burns, Fiona; Saralaya, Dinesh; Duncan, Christopher J. A.; Lillie, Patrick J.; Ramos, Alberto San Francisco; Galiza, Eva P.; Heath, Paul; Girard, Bethany; Parker, Christy; Rust, Dondi; Mehta, Shraddha; de Windt, Elizabeth; Sutherland, Andrea; Tomassini, Joanne E.; Dutko, Frank J.; Chalkias, Spyros; Deng, Weiping; Chen, Xing; Feng, Jing; Tracy, Laree; Zhou, Honghong; Miller, Jacqueline M.; Das, Rituparna 分享 收藏
Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history 疫苗接种后的Omicron感染可增强依赖于感染史的广泛免疫反应 Hornsby, Hailey R.; Nicols, Alexander R.; Longet, Stephanie; Liu, Chang; Tomic, Adriana; Angyal, Adrienn; Kronsteiner, Barbara K.; Tyerman, Jessica K.; Tipton, Tom; Zhang, Peijun; Gallis, Marta; Supasa, Piyada; Selvaraj, Muneeswaran; Abraham, Priyanka; Neale, Isabel; Ali, Mohammad A.; Barratt, Natalie M.; Nell, Jeremy; Gustafsson, Lotta; Strickland, Scarlett; Grouneva, Irina; Rostron, Timothy C.; Moore, Shona M.; Hering, Luisa L.; Dobson, Susan L.; Bibi, Sagida; Mongkolsapaya, Juthathip; Lambe, Teresa; Wootton, Dan; Hall, Victoria; Hopkins, Susan; Dong, Tao; Barnes, Eleanor; Screaton, Gavin; Richter, Alex; Turtle, Lance; Rowland-Jones, Sarah L.; Carroll, Miles; Duncan, Christopher J. A.; Klenerman, Paul; Dunachie, Susanna J.; Payne, Rebecca P.; de Silva, Thushan, I 分享 收藏
Human inherited complete STAT2 deficiency underlies inflammatory viral diseases Bucciol, Giorgia; Moens, Leen; Ogishi, Masato; Rinchai, Darawan; Matuozzo, Daniela; Momenilandi, Mana; Kerrouche, Nacim; Cale, Catherine M.; Treffeisen, Elsa R.; Al Salamah, Mohammad; Al-Saud, Bandar K.; Lachaux, Alain; Duclaux-Loras, Remi; Meignien, Marie; Bousfiha, Aziz; Benhsaien, Ibtihal; Shcherbina, Anna; Roppelt, Anna; COVID Human Genetic Effort, C. O. V. I. D. Human Genetic Effort; Gothe, Florian; Houhou-Fidouh, Nadhira; Hackett, Scott J.; Bartnikas, Lisa M.; Maciag, Michelle C.; Alosaimi, Mohammed F.; Chou, Janet; Mohammed, Reem W.; Freij, Bishara J.; Jouanguy, Emmanuelle; Zhang, Shen-Ping; Boisson-Dupuis, Stephanie; Beziat, Vivien; Zhang, Qian; Duncan, Christopher J. A.; Hambleton, Sophie; Casanova, Jean-Laurent; Meyts, Isabelle 分享 收藏
Persistence of immune response in heterologous COVID vaccination schedules in the Com-COV2 study-A single-blind, randomised trial incorporating mRNA, viral-vector and protein-adjuvant vaccines Com-COV2研究中异源COVID疫苗接种计划中免疫反应的持久性-一项纳入mRNA，病毒载体和蛋白质佐剂疫苗的单盲，随机试验 Shaw, Robert H.; Greenland, Melanie; Stuart, Arabella S. V.; Aley, Parvinder K.; Andrews, Nick J.; Cameron, J. Claire; Charlton, Sue; Clutterbuck, Elizabeth A.; Collins, Andrea M.; Darton, Tom; Dinesh, Tanya; Duncan, Christopher J. A.; Faust, Saul N.; Ferreira, Daniela M.; Finn, Adam; Goodman, Anna L.; Green, Christopher A.; Hallis, Bassam; Heath, Paul T.; Hill, Helen; Lambe, Teresa; Libri, Vincenzo; Lillie, Patrick J.; Morey, Ella; Mujadidi, Yama F.; Payne, Ruth; Plested, Emma L.; Provstgaard-Morys, Samuel; Ramasamy, Maheshi N.; Ramsay, Mary; Read, Robert C.; Robinson, Hannah; Screaton, Gavin R.; Singh, Nisha; Turner, David P. J.; Turner, Paul J.; White, Rachel; Nguyen-Van-Tam, Jonathan S.; Liu, Xinxue; Snape, Matthew D. 分享 收藏
Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia Hanrath, Aidan T.; Hatton, Catherine F.; Gothe, Florian; Browne, Cathy; Vowles, Jane; Leary, Peter; Cockell, Simon J.; Cowley, Sally A.; James, William S.; Hambleton, Sophie; Duncan, Christopher J. A. 分享 收藏
Aberrant inflammatory responses to type I interferon in STAT2 or IRF9 deficiency Gothe, Florian; Stremenova Spegarova, Jarmila; Hatton, Catherine F.; Griffin, Helen; Sargent, Thomas; Cowley, Sally A.; James, William; Roppelt, Anna; Shcherbina, Anna; Hauck, Fabian; Reyburn, Hugh T.; Duncan, Christopher J. A.; Hambleton, Sophie 分享 收藏
Impact of vaccination on hospitalization and mortality from COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience Shields, Adrian M.; Tadros, Susan; Al-Hakim, Adam; Nell, Jeremy M.; Lin, Me Me Nay; Chan, Michele; Goddard, Sarah; Dempster, John; Dziadzio, Magdalena; Patel, Smita Y.; Elkalifa, Shuayb; Huissoon, Aarnoud; Duncan, Christopher J. A.; Herwadkar, Archana; Khan, Sujoy; Bethune, Claire; Elcombe, Suzanne; Thaventhiran, James; Klenerman, Paul; Lowe, David M.; Savic, Sinisa; Burns, Siobhan O.; Richter, Alex G. 分享 收藏
mRNA vaccination drives differential mucosal neutralizing antibody profiles in naive and SARS-CoV-2 previously-infected individuals Longet, Stephanie; Hargreaves, Alexander; Healy, Saoirse; Brown, Rebecca; Hornsby, Hailey R.; Meardon, Naomi; Tipton, Tom; Barnes, Eleanor; Dunachie, Susanna; Duncan, Christopher J. A.; Klenerman, Paul; Richter, Alex; Turtle, Lance; de Silva, Thushan I.; Carroll, Miles W. 分享 收藏
Safety and immunogenicity of the inactivated whole-virus adjuvanted COVID-19 vaccine VLA2001: A randomized, dose escalation, double-blind phase 1/2 clinical trial in healthy adults 灭活全病毒佐剂新型冠状病毒肺炎疫苗VLA2001的安全性和免疫原性: 健康成人的随机，剂量递增，双盲1/2期临床试验 Lazarus, Rajeka; Taucher, Christian; Brown, Claire; Ramljak, Irena Corbic; Danon, Leon; Dubischar, Katrin; Duncan, Christopher J. A.; Eder-Lingelbach, Susanne; Faust, Saul N.; Green, Christopher; Gokani, Karishma; Hochreiter, Romana; Wright, Johanna Kellett; Kwon, Dowan; Middleditch, Alexander; Munro, Alasdair P. S.; Naker, Kush; Penciu, Florentina; Price, David; Querton, Benedicte; Riaz, Tawassal; Ross-Russell, Amy; Sanchez-Gonzalez, Amada; Wardle, Hayley; Warren, Sarah; Finn, Adam 分享 收藏
Clinical features and management of human monkeypox: a retrospective observational study in the UK Adler, Hugh; Gould, Susan; Hine, Paul; Snell, Luke B.; Wong, Waison; Houlihan, Catherine F.; Osborne, Jane C.; Rampling, Tommy; Beadsworth, Mike Bj; Duncan, Christopher Ja; Dunning, Jake; Fletcher, Tom E.; Hunter, Ewan R.; Jacobs, Michael; Khoo, Saye H.; Newsholme, William; Porter, David; Porter, Robert J.; Ratcliffe, Libuse; Schmid, Matthias L.; Semple, Malcolm G.; Tunbridge, Anne J.; Wingfield, Tom; Price, Nicholas M. 分享 收藏
Conjunctival epithelial cells resist productive SARS-CoV-2 infection Jackson, Robert M.; Hatton, Catherine F.; Spegarova, Jarmila Stremenova; Georgiou, Maria; Collin, Joseph; Stephenson, Emily; Verdon, Bernard; Haq, Iram J.; Hussain, Rafiqul; Coxhead, Jonathan M.; Mudhar, Hardeep-Singh; Wagner, Bart; Hasoon, Megan; Davey, Tracey; Rooney, Paul; Khan, C. M. Anjam; Ward, Chris; Brodlie, Malcolm; Haniffa, Muzlifah; Hambleton, Sophie; Armstrong, Lyle; Figueiredo, Francisco; Queen, Rachel; Duncan, Christopher J. A.; Lako, Majlinda 分享 收藏
DUAL ANTIRETROVIRAL THERAPY WITH DOLUTEGRAVIR PLUS LAMIVUDINE: REAL WORLD EXPERIENCE FROM THE NORTH EAST OF ENGLAND Procter, Isabella; Hunter, Ewan; Dixon, Jill; Duncan, Christopher; Evans, Adam; Payne, Brendan; Price, Ashley; Schmid, Matthias; Schwab, Ulrich; Taha, Yusri; Duncan, Sarah 分享 收藏
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