Charles Kooperberg

Fred Hutchinson Cancer Research Center

H指数:130

被引数:7.6万

个人简介

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教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

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Transcriptomic signatures of lipids in blood provide hypotheses of functional mechanisms linked to lipid metabolism and immune-cell regulation

血液中脂质转录组特征为与脂质代谢和免疫细胞调控相关的功能机制提供了假说

Human Molecular Genetics

IF3.2

2026-10-290

OAAI

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk

多群体全基因组关联研究荟萃分析鉴定膀胱癌易感位点并突出吸烟相关风险的遗传调控

Nature Communications

IF15.7

2026-08-080

Ludmila Prokunina-Olsson; Oscar Florez-Vargas; Michael G. Levin; Diptavo Dutta; Charles E. Breeze; Lauren M. Hurwitz; Wusheng Yan; Philippe Lamy; Brenen W. Papenberg; Kevin Wang; Chia-Han Lee; Roger L. Milne; Jian Gu; Caroline Y. Um; Vijai Joseph; Helena Furberg; Florence Le Calvez-Kelm; Adriana Lori; Parichoy Pal Choudhury; Nina Afshar; Manolis Kogevinas; Kenneth Offit; Sita H. Vermeulen; Evangelina López de Maturana; Demetrius Albanes; Mark P. Purdue; Victoria K. Cortessis; Margaret R. Karagas; Charles Kooperberg; Marc Bjurlin; Deborah A. Tadesse; Steven C. Moore; Wen-Yi Huang; Christopher A. Haiman; Mariana C. Stern; A. Heather Eliassen; Lorelei A. Mucci; Katja K. Aben; Tessel E. Galesloot; Anurag Verma; Soichiro Yoshino; Keiko Hikino; Chikashi Terao; Thorunn Rafnar; Koichi Matsuda; Taro Shuin; Montserrat Garcia-Closas; Francisco X. Real; Lambertus A. Kiemeney; Stephen J. Chanock; Núria Malats; Debra T. Silverman; Lars Dyrskjot; Nathaniel Rothman; Scott M. Damrauer; Stella Koutros; Jeffrey S. Damrauer

Physical activity and sitting over 9 years of the Women’s Health Initiative Strong & Healthy (WHISH) randomized physical activity intervention trial in older women

9年期间女性健康倡议强健与健康（WHISH）随机身体活动干预试验中老年女性的身体活动与久坐

Journals of Gerontology Series A-Biological Sciences and Medical Sciences

IF3.8

2026-07-310

OAAI

Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed

TOPMed中表达和剪接数量性状位点的跨队列分析

Science

IF45.8

2026-07-160

PRE

Peter Orchard; Thomas W. Blackwell; Linda Kachuri; Peter J. Castaldi; Michael H. Cho; Stephanie A. Christenson; Peter Durda; Stacey Gabriel; Craig P. Hersh; Scott Huntsman; Seungyong Hwang; Roby Joehanes; Mari Johnson; Xingnan Li; Honghuang Lin; Ching-Ti Liu; Yongmei Liu; Angel C. Y. Mak; Ani W. Manichaikul; David T. Paik; Aabida Saferali; Joshua D. Smith; Kent D. Taylor; Russell P. Tracy; Jiongming Wang; Mingqiang Wang; Joshua S. Weinstock; Jeffrey Weiss; Heather E. Wheeler; Ying Zhou; Sebastian Zöllner; Joseph C. Wu; Luisa Mestroni; Sharon Graw; Matthew R. G. Taylor; Victor E. Ortega; W. Craig Johnson; Weiniu Gan; Goncalo Abecasis; Deborah A. Nickerson; Namrata Gupta; Kristin Ardlie; Prescott G. Woodruff; Russell P. Bowler; Deborah A. Meyers; Alex Reiner; Charles Kooperberg; Elad Ziv; Ramachandran S. Vasan; Martin G. Larson; L. Adrienne Cupples; Edwin K. Silverman; Stephen S. Rich; Nancy Heard-Costa; Hua Tang; Jerome I. Rotter; Albert V. Smith; Daniel Levy; ; ; François Aguet; Laura J. Scott; Laura M. Raffield; Stephen C. J. Parker

Women's health initiative strong and healthy silent atrial fibrillation recording study: Rationale, study design, and baseline data

女性健康倡议强健与健康新闻：心房颤动记录研究：理论基础、研究设计和基线数据

American Heart Journal

IF3.5

2026-06-011

OAAI

Co-occurring clonal hematopoiesis exhibits strong selection and high leukemia risk

同时发生的克隆造血具有很强的选择性和高的白血病风险

Nature Communications

IF15.7

2026-05-210

OAAI

Kara M. Barnao; Aubrey K. Hubbard; Irenaeus C. C. Chan; Weiyin Zhou; Yasminka A. Jakubek; Giulio Genovese; Wendy S. W. Wong; Rebecca L. Kelly; Corey D. Young; Derek W. Brown; Wen-Yi Huang; Neal D. Freedman; Kristine Jones; Amy Hutchinson; Belynda Hicks; Duc Tran; Donna Arnett; Kathleen C. Barnes; Joshua C. Bis; Eric Boerwinkle; Jennifer A. Brody; April P. Carson; Daniel I. Chasman; Michael H. Cho; Pinkal Desai; Margaret F. Doyle; Myriam Fornage; Xiuqing Guo; Nancy Heard-Costa; Marguerite Ryan Irvin; Andrew D. Johnson; Sharon L. R. Kardia; Charles Kooperberg; Daniel Levy; Joshua P. Lewis; Yun Li; Ruth J. F. Loos; Taralynn M. Mack; Rasika A. Mathias; Braxton D. Mitchell; Kari E. North; Nathan Pankratz; Patricia A. Peyser; Michael H. Preuss; Bruce M. Psaty; Laura M. Raffield; Susan Redline; Stephen S. Rich; Jerome I. Rotter; Edwin K. Silverman; Albert V. Smith; Jennifer A. Smith; Adrienne Stilp; Yin Cao; Paul Scheet; Alexander P. Reiner; Alexander G. Bick; Stephen J. Chanock; Paul L. Auer; Kelly L. Bolton; Mitchell J. Machiela

An Efficient Lasso Framework for Admixture-Aware Polygenic Scores

一种高效的混杂因素感知多基因评分框架

Human Genetics and Genomics Advances

IF3.6

2026-05-180

OAAI

Admixture-informed polygenic risk reporting using the ePRS framework

基于admixture信息的ePRS框架多基因风险报告

Nature Communications

IF15.7

2026-04-300

OAAI

Yu-Jyun Huang; Nuzulul Kurniansyah; Matthew O. Goodman; Brian W. Spitzer; Jiongming Wang; Adrienne Stilp; Cecelia Laurie; Paul S. de Vries; Han Chen; Yuan-I Min; Mario Sims; Gina M. Peloso; Xiuqing Guo; Joshua C. Bis; Jennifer A. Brody; Laura M. Raffield; Jennifer A. Smith; Wei Zhao; Jerome I. Rotter; Stephen S. Rich; Susan Redline; Myriam Fornage; Robert Kaplan; Nora Franceschini; Daniel Levy; Alanna C. Morrison; Eric Boerwinkle; Nicholas L. Smith; Charles Kooperberg; Bruce M. Psaty; Sebastian Zöllner; Tamar Sofer

An integrated germline and somatic genomic model for coronary artery disease

冠心病整合了生殖细胞和体细胞基因组模型

Nature Communications

IF15.7

2026-03-260

OAAI

Xiong Yang; Min Seo Kim; Xinyu Zhu; Md Mesbah Uddin; Tetsushi Nakao; So Mi Jemma Cho; Satoshi Koyama; Tingfeng Xu; Laurens F. Reeskamp; Rufan Zhang; Zhaoqi Liu; Yunga A; Paul S. de Vries; Ramachandran S. Vasan; Eric Boerwinkle; Alanna C. Morrison; Bruce M. Psaty; Russell P. Tracy; Susan R. Heckbert; Michael H. Cho; Jeong H. Yun; Nicholette D. Palmer; Donald W. Bowden; Joanne M. Murabito; Daniel Levy; Nancy L. Heard-Costa; George T. O’Connor; Lewis C. Becker; Brian G. Kral; Lisa R. Yanek; Laura M. Raffield; Bertha Hidalgo; Jerome I. Rotter; Stephen S. Rich; Kent D. Taylor; Wendy S. Post; Charles Kooperberg; Alexander P. Reiner; Braxton D. Mitchell; Sharon L. R. Kardia; Jennifer A. Smith; Patricia A. Peyser; Lawrence F. Bielak; Dong Keon Yon; Hong-Hee Won; Donna K. Arnett; Albert V. Smith; Stacey B. Gabriel; Patrick T. Ellinor; Pradeep Natarajan; Minxian Wang; Akl C. Fahed

CD39 polymorphism enables lung thrombosis in sickle cell disease

CD39多态性导致镰状细胞病患者发生肺血栓形成。

Nature Communications

IF15.7

2026-01-140

OAAI

Tomasz Brzoska; Tomasz W. Kaminski; Omika Katoch; Elizaveta V. Menchikova; Adekunle E. Alagbe; Sarah E. Tashbook; Stevan P. Tofovic; Jude C. Jonassaint; Claudette M. St. Croix; Simon C. Watkins; Shane Howe; Joshua J. Field; Amanda A. Seyerle; Tirthadipa Pradhan-Sundd; Cecilia Laurie; Nathan D. Pankratz; Nicholas L. Smith; Ellen L. Goode; James S. Pankow; Charles Kooperberg; Gregory J. Kato; Yingze Zhang; Enrico M. Novelli; Mark T. Gladwin; Edwin K. Jackson; Seyed M. Nouraie; Prithu Sundd

Trans-ancestry GWAS of hot flashes reveals potent treatment target and overlap with psychiatric disorders

跨人群GWAS研究揭示潮热的治疗靶点及其与精神障碍的关联

Communications Medicine

IF6.3

2026-01-060

OAAI

cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions

cellSTAAR：整合基于单细胞测序的功能数据，以提升非编码区域稀有变异关联检验的功效

Nature Methods

IF32.1

2025-12-310

PRE

Eric Van Buren; Yi Zhang; Xihao Li; Margaret Sunitha Selvaraj; Zilin Li; Hufeng Zhou; Nicholette D. Palmer; Donna K. Arnett; John Blangero; Eric Boerwinkle; Brian E. Cade; Jenna C. Carlson; April P. Carson; Yii-Der Ida Chen; Joanne Curran; Ravindranath Duggirala; Myriam Fornage; Nora Franceschini; Misa Graff; Charles Gu; Xiuqing Guo; Jiang He; Nancy Heard-Cosa; Lifang Hou; Yi-Jen Hung; Rita R. Kalyani; Sharon L. R. Kardia; Eimear Kenny; Charles Kooperberg; Brian G. Kral; Leslie Lange; Dan Levy; Changwei Li; Simin Liu; Donald Lloyd-Jones; Ruth J. F. Loos; Ani W. Manichaikul; Lisa Warsinger Martin; Rasika Mathias; Ryan L. Minster; Braxton D. Mitchell; Josyf C. Mychaleckyj; Take Naseri; Kari North; Jeff O’Connell; James A. Perry; Patricia A. Peyser; Bruce M. Psaty; Laura M. Raffield; Ramachandran S. Vasan; Susan Redline; Alex P. Reiner; Stephen S. Rich; Jennifer A. Smith; Brian Spitzer; Hua Tang; Kent D. Taylor; Russell Tracy; Satupa’itea Viali; Lisa Yanek; Wei Zhao; Jerome I. Rotter; Gina M. Peloso; Pradeep Natarajan; Xihong Lin

Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy

全基因组甲基化关联研究：核DNA甲基化与线粒体异质性之间的关系

Nature Communications

IF15.7

2025-12-020

OAAI

Meng Lai; Kyeezu Kim; Yinan Zheng; Christina A. Castellani; Scott M. Ratliff; Mengyao Wang; Xue Liu; Jeffrey Haessler; Tianxiao Huan; Kwadwo Bonsu; Charles Newcomb; Kyler McKessy; Lawrence F. Bielak; Wei Zhao; Roby Joehanes; Jiantao Ma; Xiuqing Guo; JoAnn E. Manson; Megan L. Grove; Jan Bressler; Kent D. Taylor; Tuuli Lappalainen; Silva Kasela; Thomas W. Blackwell; Nicole J. Lake; Jessica D. Faul; Kendra R. Ferrier; Stephen C. Ekker; Lifang Hou; Charles Kooperberg; Alexander P. Reiner; Kai Zhang; Patricia A. Peyser; Myriam Fornage; Eric Boerwinkle; Laura M. Raffield; April P. Carson; Stephen S. Rich; Yongmei Liu; Daniel Levy; Jerome I. Rotter; Jennifer A. Smith; Dan E. Arking; Chunyu Liu

Human plasma proteomic profile of clonal hematopoiesis

克隆性造血的人类血浆蛋白质组谱

Nature Communications

IF15.7

2025-11-270

OAAI

Zhi Yu; Amélie Vromman; Ngoc Quynh H. Nguyen; Art Schuermans; Linke Li; Thiago Rentz; Tetsushi Nakao; Shamsudheen K. Vellarikkal; Md Mesbah Uddin; Abhishek Niroula; Gabriel Griffin; Michael C. Honigberg; Amy E. Lin; Christopher J. Gibson; Daniel H. Katz; Usman A. Tahir; Shi Fang; Jacqueline S. Dron; Michael Pan; Sara Haidermota; Shriienidhie Ganesh; Tajmara Antoine; Joshua Weinstock; Thomas R. Austin; Ramachandran S. Vasan; Gina M. Peloso; Whitney Hornsby; Peter Ganz; JoAnn E. Manson; Bernhard Haring; Charles Kooperberg; Alexander P. Reiner; Joshua C. Bis; Bruce M. Psaty; Yuan-I Min; Adolfo Correa; Leslie A. Lange; Wendy S. Post; Jerome I. Rotter; Stephen S. Rich; James G. Wilson; Benjamin L. Ebert; Bing Yu; Christie M. Ballantyne; Josef Coresh; Vijay G. Sankaran; Alexander G. Bick; Siddhartha Jaiswal; Robert E. Gerszten; Peter Libby; Rajat M. Gupta; Pradeep Natarajan

Integrating whole genome and transcriptome sequencing to characterize the genetic architecture of isoform variation

整合全基因组与转录组测序以表征异构体变异的遗传结构

Nature Communications

IF15.7

2025-11-220

OAAI

Different diabetes types and pancreatic ductal adenocarcinoma: a Mendelian randomization and pathway/gene-set analysis

不同糖尿病类型和胰腺导管腺癌：一项孟德尔随机化与通路/基因集分析

JNCI: Journal of the National Cancer Institute

IF0

2025-11-090

PRE

Ting Zhang, PhD; Xing Hua, PhD; Chirayu Mohindroo, MBBS; Xiaoyu Wang, MS; Diptavo Dutta, PhD; Jia Liu, PhD; Shilpa Katta, MS; Shengchao A Li, MS; Jiahui Wang, MS; Samuel O Antwi, PhD; Alan A Arslan, MD; Laura E Beane Freeman, PhD; Paige M Bracci, PhD, MPH; Federico Canzian, PhD; Mengmeng Du, PhD; Steven Gallinger, PhD; Phyllis J Goodman, MS; Verena Katzke, PhD; Charles Kooperberg, PhD; Loic Le Marchand, MD, PhD; Rachel E Neale, PhD; Alpa V Patel, PhD; Sandra Perdomo, PhD; Xiao-Ou Shu, MD, PhD, MPH; Kala Visvanathan, MD, MHS; Stephen K Van Den Eeden, PhD; Emily White, PhD, MS; Wei Zheng, MD, PhD, MPH; Demetrius Albanes, MD; Gabriella Andreotti, PhD, MPH; William R Bamlet, PhD; Paul Brennan, PhD; Julie E Buring, PhD; Stephen J Chanock, MD; Yu Chen, PhD, MPH; Burcu Darst, PhD; Pietro Ferrari, PhD; Edward L Giovannucci, MD, PhD; Michael Goggins, MD; Christopher Haiman, PhD; Manal Hassan, MD, MPH, PhD; Elizabeth A Holly, PhD, MPH; Rayjean J Hung, PhD; Miranda R Jones, PhD, MHS; Peter Kraft, PhD; Robert C Kurtz, MD; Núria Malats, MD, PhD; Steven C Moore, PhD, MPH; Kimmie Ng, MD, MPH; Ann L Oberg, PhD; Irene Orlow, PhD, MS; Ulrike Peters, PhD, MPH; Miquel Porta, MD, MPH, PhD; Kari G Rabe, MS; Nathaniel Rothman, MD, MPH, MHS; Maria-José Sánchez, PhD; Howard D Sesso, PhD, MPH; Debra T Silverman, PhD; Melissa C Southey, PhD; Caroline Y Um, PhD, MPH, RD; James Yarmolinsky, PhD; Herbert Yu, MD, PhD; Chen Yuan, PhD; Jun Zhong, PhD; Brian M Wolpin, MD, MPH; Harvey A Risch, MD, PhD; Laufey T Amundadottir, PhD; Alison P Klein, PhD, MHS; Kai Yu, PhD; Haoyu Zhang, PhD; Rachael Z Stolzenberg-Solomon, PhD, MPH, RD

Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations

非白血病源性体细胞点突变的遗传决定因素及其基因组后果

Nature Communications

IF15.7

2025-10-160

OAAI

Joshua S. Weinstock; Sharjeel A. Chaudhry; Maria Ioannou; Maria Viskadourou; Paula Reventun; Yasminka A. Jakubek; L. Alexander Liggett; Cecelia Laurie; Jai G. Broome; Alyna Khan; Kent D. Taylor; Xiuqing Guo; Patricia A. Peyser; Eric Boerwinkle; Nathalie Chami; Eimear E. Kenny; Ruth J. Loos; Bruce M. Psaty; Russell P. Tracy; Jennifer A. Brody; Jeong H. Yun; Michael H. Cho; Ramachandran S. Vasan; Sharon L. Kardia; Jennifer A. Smith; Laura M. Raffield; Aurelian Bidulescu; Emily C. O’Brien; Mariza de Andrade; Jerome I. Rotter; Stephen S. Rich; Russell P. Tracy; Yii Der Ida Chen; C. Charles. Gu; Chao A. Hsiung; Charles Kooperberg; Bernhard Haring; Rami Nassir; Rasika Mathias; Alex Reiner; Vijay G. Sankaran; Charles J. Lowenstein; Thomas W. Blackwell; Goncalo R. Abecasis; Albert V. Smith; Hyun M. Kang; Pradeep Natarajan; Siddhartha Jaiswal; Alexander Bick; Wendy S. Post; Paul Scheet; Paul Auer; Theodoros Karantanos; Alexis Battle; Marios Arvanitis

Polygenic risk score for type 2 diabetes shows context-dependent effects across populations

2型糖尿病的多基因风险评分在人群中显示出依赖情境的影响

Nature Communications

IF15.7

2025-10-010

OAAI

Boya Guo; Yanwei Cai; Daeeun Kim; Roelof A. J. Smit; Zhe Wang; Kruthika R. Iyer; Austin T. Hilliard; Jeffrey Haessler; Ran Tao; K. Alaine Broadaway; Yujie Wang; Nikita Pozdeyev; Frederik F. Stæger; Chaojie Yang; Brett Vanderwerff; Amit D. Patki; Lauren Stalbow; Meng Lin; Nicholas Rafaels; Jonathan Shortt; Laura Wiley; Maggie Stanislawski; Jack Pattee; Lea Davis; Peter S. Straub; Megan M. Shuey; Nancy J. Cox; Nanette R. Lee; Marit E. Jørgensen; Peter Bjerregaard; Christina Larsen; Torben Hansen; Ida Moltke; James B. Meigs; Daniel O. Stram; Xianyong Yin; Xiang Zhou; Kyong-Mi Chang; Shoa L. Clarke; Rodrigo Guarischi-Sousa; Joanna Lankester; Philip S. Tsao; Steven Buyske; Mariaelisa Graff; Laura M. Raffield; Quan Sun; Lynne R. Wilkens; Christopher S. Carlson; Charles B. Easton; Simin Liu; JoAnn E. Manson; Loïc L. Marchand; Christopher A. Haiman; Karen L. Mohlke; Penny Gordon-Larsen; Anders Albrechtsen; Michael Boehnke; Stephen S. Rich; Ani Manichaikul; Jerome I. Rotter; Noha A. Yousri; Ryan M. Irvin; Chris Gignoux; Kari E. North; Ruth J. F. Loos; Themistocles L. Assimes; Ulrike Peters; Charles Kooperberg; Sridharan Raghavan; Heather M. Highland; Burcu F. Darst

Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program

与胰岛素抵抗相关的遗传评分与 ancestry 多样化队列中神经病学结局的关联：来自精准医学跨组学计划 (TOPMed) 的数据

Communications Biology

IF5.1

2025-09-240

OAAI

Chloé Sarnowski; Yixin Zhang; Farah Ammous; Lincoln M. P. Shade; Daniel DiCorpo; Xueqiu Jian; Donna K. Arnett; Thomas R. Austin; Alexa Beiser; Joshua C. Bis; John Blangero; Eric Boerwinkle; Jan Bressler; Joanne E. Curran; Charles S. DeCarli; Harsha Doddapaneni; Josée Dupuis; David W. Fardo; Jose C. Florez; Stacey Gabriel; Richard A. Gibbs; David C. Glahn; Namrata Gupta; Hector M. González; Kevin A. González; Konstantinos Hatzikotoulas; Kathleen M. Hayden; Susan R. Heckbert; Bertha Hidalgo; Alicia Huerta-Chagoya; Timothy M. Hughes; Sharon L. R. Kardia; Charles L. Kooperberg; Lenore J. Launer; W. T. Longstreth; Ravi Mandla; Rasika A. Mathias; Andrew P. Morris; Thomas H. Mosley; Ilya M. Nasrallah; Paul Nyquist; Bruce M. Psaty; Qibin Qi; Laura M. Raffield; Nigel W. Rayner; Alexander P. Reiner; Claudia L. Satizabal; Elizabeth Selvin; Magdalena D. R. Sevilla-Gonzalez; Albert V. Smith; Jennifer A. Smith; Kirk Smith; Beverly M. Snively; Lorraine Southam; Tamar Sofer; Ken Suzuki; Henry J. Taylor; Miriam S. Udler; Karine A. Viaud-Martinez; Sylvia Wassertheil-Smoller; Alexis C. Wood; Lisa R. Yanek; Xianyong Yin; Alisa K. Manning; Jerome I. Rotter; Stephen S. Rich; James B. Meigs; Myriam Fornage; Sudha Seshadri; Alanna C. Morrison

Genetic architecture and analysis practices of circulating metabolites in the NHLBI Trans-Omics for Precision Medicine Program

循环代谢物的遗传结构与分析实践：美国国立心肺血液研究所精准医学跨组学计划

american journal of human genetics

IF0

2025-09-180

PRE

Nannan Wang; Franklin P. Ockerman; Laura Y. Zhou; Megan L. Grove; Taryn Alkis; John Barnard; Russell P. Bowler; Clary B. Clish; Shinhye Chung; Emily Drzymalla; Anne M. Evans; Nora Franceschini; Robert E. Gerszten; Madeline G. Gillman; Scott R. Hutton; Rachel S. Kelly; Charles Kooperberg; Martin G. Larson; Jessica Lasky-Su; Deborah A. Meyers; Prescott G. Woodruff; Alexander P. Reiner; Stephen S. Rich; Jerome I. Rotter; Edwin K. Silverman; Ramachandran S. Vasan; Scott T. Weiss; Kari E. Wong; Alexis C. Wood; Lang Wu; Ronit Yarden; Thomas W. Blackwell; Albert V. Smith; Han Chen; Laura M. Raffield; Bing Yu

Charles Kooperberg

个人简介

教育背景

工作经历

荣誉奖项

研究方向