Janey L. Wiggs - Publications, H-index & Citations

Janey L. Wiggs

Harvard University

73H指数

534论文数

1.8W被引数

收录论文 137

发表时间

Working toward Clinical Implementation of Glaucoma Polygenic Risk Scores 向青光眼多基因风险评分的临床应用迈进

Ophthalmology

IF9.5

2026-09-07

PREAI

Janey L. Wiggs

ChatGPT-Assisted Glaucoma Diagnosis: A Health-Equitable Multi-Ancestry Analysis using Visual Field and Optical Coherence Tomography Data ChatGPT辅助青光眼诊断：一项基于视力和光学相干断层扫描数据的健康公平性多血统分析

American Journal of Ophthalmology

IF4.2

2025-12-03

OAAI

Andy S. Huang; Anthony Fam; Hetince Zhao; Nicole Paulescu; Anna Fabczak-Kubicka; Janey L. Wiggs; Nazlee Zebardast; David S. Friedman; Ron Do; Kanza Aziz; Jae Hee Kang; Tobias Elze; Mengyu Wang; Alon Harris; Tak Yee Tania Tai; James C. Tsai; Louis R. Pasquale

Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging 鉴定来自三个欧洲血统队列（包括加拿大老龄化纵向研究）中与青光眼和眼内压测量相关的血液来源DNA甲基化生物标志物

Epigenetics

IF3.2

2025-10-17

OAAI

Xiaofan Jiang; Omar A. Mahroo; Anthony P Khawaja; Dorota Skowronska-Krawczyk; David A. Mackey; Janey L. Wiggs; The International Glaucoma Genetics Consortium, Christopher J. Hammond; Pirro G. Hysi; Christopher G. Bell

Using genetics for glaucoma screening and risk stratification: The LXXXII Edward Jackson Memorial Lecture 利用遗传学进行青光眼筛查和风险分层：第LXXXII届爱德华·杰克逊纪念讲座

American Journal of Ophthalmology

IF4.2

2025-10-10

PREAI

Janey L. Wiggs

Genomic structural equation Modeling analysis of glaucoma Endophenotypes: investigating genetic architecture and non-intraocular pressure mechanisms 青光眼内表型的基因组结构方程模型分析：探究遗传结构和非眼内压机制

HUMAN MOLECULAR GENETICS

IF3.2

2025-10-01

PREAI

Marzban, Maryam; Diaz-Torres, Santiago; Thorp, Jackson; Ong, Jue Sheng; Khawaja, Anthony P.; Hammond, Christopher J.; Hysi, Pirro G.; Pasquale, Louis R.; Kraft, Peter; Kang, Jae H.; Hewitt, Alex W.; Mackey, David A.; Craig, Jamie E.; Wiggs, Janey L.; MacGregor, Stuart; Gharahkhani, Puya

Glaucoma Genetics: Lessons Learned and the New Frontier 青光眼遗传学：经验教训与新前沿

Ophthalmology Glaucoma

IF3.2

2025-09-03

PREAI

Janey L. Wiggs; Louis R. Pasquale

Metabolomic Signatures and Predictive Utility of LOXL1-Associated Genetic Risk Scores for Exfoliation Syndrome/Glaucoma in US Cohorts 代谢组学特征及LOXL1相关遗传风险评分对美国人群中的剥脱综合征/青光眼的预测效用

Metabolites 2025, Vol. 15, Page 582

IF3.7

2025-08-30

OAAI

Namuunaa Juramt; Oana A. Zeleznik; Louis R. Pasquale; Janey L. Wiggs; Jae H. Kang

Genetic Risk for Open-Angle Glaucoma Subtypes Is Associated with Specific Visual Field Defect Classes 开角型青光眼亚型的遗传风险与特定的视野缺损类别相关联

Ophthalmology

IF9.5

2025-04-11

PREAI

Sayuri Sekimitsu; Kavin Selvan; Yan Zhao; Saber Kazeminasab Hashemabad; Mohammad Eslami; Mengyu Wang; Tobias Elze; Ayellet V. Segrè; Joni A. Turunen; Aarno Palotie; Joel Rämō; Janey L. Wiggs; Louis R. Pasquale; Jae H. Kang; Nazlee Zebardast

Childhood or adolescent abuse and primary open-angle glaucoma in a longitudinal cohort of women 儿童期或青少年期虐待与女性纵向队列中的原发性开角型青光眼

EYE

IF3.2

2025-04-10

PREAI

Yu, Megan; Hwang, Hannah H.; Roberts, Andrea L.; Koenen, Karestan C.; Wiggs, Janey L.; Pasquale, Louis R.; Kang, Jae H.

Does Age Modify the Relation Between Genetic Predisposition to Glaucoma and Various Glaucoma Traits in the UK Biobank?

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2025-02-21

OAAI

Kim, Jihye; Kang, Jae H.; Wiggs, Janey L.; Zhao, Hetince; Li, Keva; Zebardast, Nazlee; Segre, Ayellet; Friedman, David S.; Do, Ron; Khawaja, Anthony P.; Aschard, Hugues; Pasquale, Louis R.

Machine Learning on Prediagnostic Metabolite Data Identifies Etiologic Endotypes of Exfoliation Glaucoma in United States Health Professionals

OPHTHALMOLOGY SCIENCE

IF4.6

2024-12-01

OAAI

Hanyuda, Akiko; Zeleznik, Oana A.; Raita, Yoshihiko; Negishi, Kazuno; Pasquale, Louis R.; Lasky-Su, Jessica; Wiggs, Janey L.; Kang, Jae H.

Use of Diagnostic Codes for Primary Open-Angle Glaucoma Polygenic Risk Score Construction in Electronic Health Record-Linked Biobanks

AMERICAN JOURNAL OF OPHTHALMOLOGY

IF4.2

2024-11-01

PREAI

Tran, Jessica H.; Kang, Joyce; Han, Elaine; Gupta, Urvi; Seresirikachorn, Kasem; Vy, Ha My T.; Zhao, Yan; Rocheleau, Ghislain; Luo, Yuyang; Lee, Rachel; Do, Ron; Friedman, David S.; Kang, Jae H.; Wiggs, Janey L.; Pasquale, Louis R.; Segre, Ayellet, V; Zebardast, Nazlee

Glaucoma-Protective Human Single-Nucleotide Polymorphism in the Angpt2 Locus Increased ANGPT2 Expression and Schlemm Canal Area in Mice-Brief Report

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2024-10-01

PREAI

Kiyota, Naoki; Onay, Tuncer; Leeaw, Phoebe; Liu, Pan; Deb, Dilip K.; Thomson, Benjamin R.; Segre, Ayellet V.; Wiggs, Janey L.; Quaggin, Susan E.

Independent Effects of Blood Pressure on Intraocular Pressure and Retinal Ganglion Cell Degeneration: A Mendelian Randomization Study 血压对眼压和视网膜神经节细胞变性的独立影响: 孟德尔随机化研究

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2024-07-19

OAAI

Rajasundaram, Skanda; Segre, Ayellet V.; Gill, Dipender; Woolf, Benjamin; Zekavat, Seyedeh M.; Burgess, Stephen; Khawaja, Anthony P.; Zebardast, Nazlee; Wiggs, Janey L.

POU6F2, a risk factor for glaucoma, myopia and dyslexia, labels specific populations of retinal ganglion cells

SCIENTIFIC REPORTS

IF3.9

2024-05-02

OAAI

Lin, Fangyu; Li, Ying; Wang, Jiaxing; Jardines, Sandra; King, Rebecca; Chrenek, Micah A.; Wiggs, Janey L.; Boatright, Jeffrey H.; Geisert, Eldon E.

Association between Diabetes and Exfoliation Syndrome A Systematic Review and Meta-Analysis of Observational Studies 糖尿病与剥脱综合征之间的关联观察性研究的系统回顾和荟萃分析

OPHTHALMOLOGY SCIENCE

IF4.6

2024-05-01

OAAI

Yu, Megan; Hwang, Hannah H.; Wiggs, Janey L.; Pasquale, Louis R.; Kang, Jae H.

Machine Learning-Derived Baseline Visual Field Patterns Predict Future Glaucoma Onset in the Ocular Hypertension Treatment Study

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2024-02-23

OAAI

Singh, Rishabh K.; Smith, Sophie; Fingert, John; Gordon, Mae; Kass, Michael; Scheetz, Todd; Segre, Ayellet V.; Wiggs, Janey; Elze, Tobias; Zebardast, Nazlee

Phenome- and genome-wide analyses of retinal optical coherence tomography images identify links between ocular and systemic health

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-01-24

PREAI

Zekavat, Seyedeh Maryam; Jorshery, Saman Doroodgar; Rauscher, Franziska G.; Horn, Katrin; Sekimitsu, Sayuri; Koyama, Satoshi; Nguyen, Trang T.; Costanzo, Maria C.; Jang, Dongkeun; Burtt, Noel P.; Kuehnapfel, Andreas; Shweikh, Yusrah; Ye, Yixuan; Raghu, Vineet; Zhao, Hongyu; Ghassemi, Marzyeh; Elze, Tobias; Segre, Ayellet V.; Wiggs, Janey L.; Del Priore, Lucian; Scholz, Markus; Wang, Jay C.; Natarajan, Pradeep; Zebardast, Nazlee

TIE1 and TEK signalling, intraocular pressure, and primary open-angle glaucoma: a Mendelian randomization study

JOURNAL OF TRANSLATIONAL MEDICINE

IF7.5

2023-11-24

OAAI

Rajasundaram, Skanda; Zebardast, Nazlee; Mehta, Puja; Khawaja, Anthony P.; Warwick, Alasdair; Duchinski, Katherine; Burgess, Stephen; Gill, Dipender; Segre, Ayellet V.; Wiggs, Janey

The Association of Physical Activity with Glaucoma and Related Traits in the UK Biobank 英国生物库中体力活动与青光眼及相关特征的关联

OPHTHALMOLOGY

IF9.5

2023-10-01

OAAI

Madjedi, Kian M.; Stuart, Kelsey V.; Chua, Sharon Y. L.; Ramulu, Pradeep Y.; Warwick, Alasdair; Luben, Robert N.; Sun, Zihan; Chia, Mark A.; Aschard, Hugues; Wiggs, Janey L.; Kang, Jae H.; Pasquale, Louis R.; Foster, Paul J.; Khawaja, Anthony P.

研究方向