未登录Predicting the Risk of Intensive Care Unit Admission in Patients With Coronavirus Disease 2019 Presenting in the Emergency Room: Development and Evaluation of the Confusion, Respiratory rate, Oxygen Saturation With or Without Concurrent Supplemental Oxygen, and Oxygen Supplementation Score
Xiang, Weiwei; Steinbeis, Fridolin; Dhindsa, Kiret; Kurth, Florian; Lingscheid, Tilman; Thibeault, Charlotte; Meyer, Hans-Jakob; Suttorp, Norbert; Mittermaier, Mirja; Stecher, Melanie; Scherer, Margarete; Hagen, Marina; Mitrov, Lazar; Geisler, Ramsia; Appel, Katharina S.; Hopff, Sina M.; Koll, Carolin; de Miranda, Susana M. Nunes; Weismantel, Christina; Reese, Jens-Peter; Heuschmann, Peter; Miljukov, Olga; Nuernberger, Carolin; Sander, Leif-Erik; Vehreschild, Joerg Janne; Witzenrath, Martin; van Smeden, Maarten; Zoller, Thomas .png)
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收藏A biomathematical model of SARS-CoV-2 in Syrian hamstersSchirm, Sibylle; Nouailles, Geraldine; Kirsten, Holger; Trimpert, Jakob; Wyler, Emanuel; Alves, Luiz Gustavo Teixeira; Landthaler, Markus; Ahnert, Peter; Suttorp, Norbert; Witzenrath, Martin; Scholz, Markus 分享 收藏 Blood eosinophil numbers as predictor of severity of community-acquired pneumonia in a prospective multicentre validation cohortWeckler, Barbara Christine; Ringshandl, Stephan; Ahnert, Peter; Pott, Hendrik; Bertrams, Wilhelm; Kutzinski, Max; Jung, Anna Lena; Laakmann, Katrin; Seidemann, Christian; Suttorp, Norbert; Witzenrath, Martin; Wildberg, Christian; Heider, Dominik; Martin, Roman; Vogelmeier, Claus Franz; Schmeck, Bernd 分享 收藏 Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19肠道菌群失调与新型冠状病毒肺炎色氨酸代谢改变和炎症反应失调有关Essex, Morgan; Pascual-Leone, Belen Millet; Loeber, Ulrike; Kuhring, Mathias; Zhang, Bowen; Bruening, Ulrike; Fritsche-Guenther, Raphaela; Krzanowski, Marta; Vernengo, Facundo Fiocca; Brumhard, Sophia; Roewekamp, Ivo; Bielecka, Agata Anna; Lesker, Till Robin; Wyler, Emanuel; Landthaler, Markus; Mantei, Andrej; Meisel, Christian; Caesar, Sandra; Thibeault, Charlotte; Corman, Victor M.; Marko, Lajos; Suttorp, Norbert; Strowig, Till; Kurth, Florian; Sander, Leif E.; Li, Yang; Kirwan, Jennifer A.; Forslund, Sofia K.; Opitz, Bastian 分享 收藏 Comparison of clinical outcomes in hospitalized patients with COVID-19 or non-COVID-19 community-acquired pneumonia in a prospective observational cohort study前瞻性观察队列研究中新型冠状病毒肺炎或non-COVID-19社区获得性肺炎住院患者的临床结局比较Meyer, Hans-Jakob; Moedl, Lukas; Unruh, Olesya; Xiang, Weiwei; Berger, Sarah; Mueller-Plathe, Moritz; Rohde, Gernot; Pletz, Mathias W.; Rupp, Jan; Suttorp, Norbert; Witzenrath, Martin; Zoller, Thomas; Mittermaier, Mirja; Steinbeis, Fridolin 分享 收藏 Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection激活素A水平在人类结核病期间升高，激活素信号轴的阻断影响小鼠对结核分枝杆菌感染的反应Nieuwenhuizen, Natalie E.; Nouailles, Geraldine; Sutherland, Jayne S.; Zyla, Joanna; Pasternack, Arja H.; Heyckendorf, Jan; Frye, Bjoern C.; Hoehne, Kerstin; Zedler, Ulrike; Bandermann, Silke; Abu Abed, Ulrike; Brinkmann, Volker; Gutbier, Birgitt; Witzenrath, Martin; Suttorp, Norbert; Zissel, Gernot; Lange, Christoph; Ritvos, Olli; Kaufmann, Stefan H. E. 分享 收藏 Preclinical analyses reveal spleen tyrosine kinase as regulator of pulmonary vasoconstrictionTabeling, Christoph; Herbert, Julia; Boiarina, Ekaterina; Hocke, Andreas C.; Danov, Olga; Sewald, Katherina; Gutbier, Birgitt; Russ, Martin; Pickerodt, Philipp A.; Spies, Claudia; Li, Mei; Michalick, Laura; Scheffel, Joerg; Maurer, Marcus; Fehrenbach, Heinz; Suttorp, Norbert; Braun, Armin; Weissmann, Norbert; Kuebler, Wolfgang M.; Witzenrath, Martin 分享 收藏 Analysis of acute COVID-19 including chronic morbidity: protocol for the deep phenotyping National Pandemic Cohort Network in Germany (NAPKON-HAP)包括慢性发病在内的急性新型冠状病毒肺炎分析: 德国深度表型全国大流行队列网络方案 (NAPKON-HAP)Steinbeis, Fridolin; Thibeault, Charlotte; Steinbrecher, Sarah; Ahlgrimm, Yvonne; Haack, Ira An; August, Dietrich; Balzuweit, Beate; Bellinghausen, Carla; Berger, Sarah; Chaplinskaya-Sobol, Irina; Cornely, Oliver; Doeblin, Patrick; Endres, Matthias; Fink, Claudia; Finke, Carsten; Frank, Sandra; Hanss, Sabine; Hartung, Tim; Hellmuth, Johannes Christian; Herold, Susanne; Heuschmann, Peter; Heyckendorf, Jan; Heyder, Ralf; Hippenstiel, Stefan; Hoffmann, Wolfgang; Kelle, Sebastian Ulrich; Knape, Philipp; Koehler, Philipp; Kretzler, Lucie; Leistner, David Manuel; Lienau, Jasmin; Lorbeer, Roberto; Lorenz-Depiereux, Bettina; Luettke, Constanze Dorothea; Mai, Knut; Merle, Uta; Meyer-Arndt, Lil Antonia; Miljukov, Olga; Muenchhoff, Maximilian; Mueller-Plathe, Moritz; Neuhann, Julia; Neuhauser, Hannelore; Nieters, Alexandra; Otte, Christian; Pape, Daniel; Pinto, Rafaela Maria; Pley, Christina; Pudszuhn, Annett; Reuken, Philipp; Rieg, Siegberg; Ritter, Petra; Rohde, Gernot; Roennefarth, Maria; Ruzicka, Michael; Schaller, Jens; Schmidt, Anne; Schmidt, Sein; Schwachmeyer, Verena; Schwanitz, Georg; Seeger, Werner; Stahl, Dana; Stobaeus, Nicole; Stubbe, Hans Christian; Suttorp, Norbert; Temmesfeld, Bettina; Thun, Sylvia; Triller, Paul; Trinkmann, Frederik; Vadasz, Istvan; Valentin, Heike; Vehreschild, Maria; von Kalle, Christof; von Lilienfeld-Toal, Marie; Weber, Joachim; Welte, Tobias; Wildberg, Christian; Wizimirski, Robert; Zvork, Saskia; Sander, Leif Erik; Vehreschild, Janne; Zoller, Thomas; Kurth, Florian; Witzenrath, Martin 分享 收藏 Pathogen spectrum of community acquired pneumonia in people living with HIV (PLWH) in the German CAPNETZ-Cohort德国CAPNETZ队列中HIV感染者 (PLWH) 的社区获得性肺炎病原体谱Schleenvoigt, Benjamin; Ankert, Juliane; Barten-Neiner, Grit; Voit, Florian; Suttorp, Norbert; Boesecke, Christoph; Hoffmann, Christian; Stolz, Daiana; Pletz, Mathias; Rohde, Gernot; Witzenrath, Martin; Panning, Marcus; Essig, Andreas; Rupp, Jan; Degen, Olaf; Stephan, Christoph; Dreher, M. 分享 收藏 Novel protein biomarkers for pneumonia and acute exacerbations in COPD: a pilot studyCOPD肺炎和急性加重的新型蛋白质生物标志物: 一项初步研究Jung, Anna Lena; Han, Maria; Griss, Kathrin; Bertrams, Wilhelm; Nell, Christoph; Greulich, Timm; Klemmer, Andreas; Pott, Hendrik; Heider, Dominik; Vogelmeier, Claus F.; Hippenstiel, Stefan; Suttorp, Norbert; Schmeck, Bernd 分享 收藏 Surface proteome of plasma extracellular vesicles as mechanistic and clinical biomarkers for malaria血浆细胞外囊泡的表面蛋白质组作为疟疾的机制和临床生物标志物Jung, Anna Lena; Moller Jorgensen, Malene; Baek, Rikke; Artho, Marie; Griss, Kathrin; Han, Maria; Bertrams, Wilhelm; Greulich, Timm; Koczulla, Rembert; Hippenstiel, Stefan; Heider, Dominik; Suttorp, Norbert; Schmeck, Bernd 分享 收藏 Cystic fibrosis transmembrane conductance regulator modulators attenuate platelet activation and aggregation in blood of healthy donors and COVID-19 patients囊性纤维化跨膜传导调节调节剂可减弱健康供体和新型冠状病毒肺炎患者血液中的血小板活化和聚集Asmus, Erik; Karle, Weronika; Brack, Markus C.; Wittig, Corey; Behrens, Felix; Reinshagen, Leander; Pfeiffer, Moritz; Schulz, Sabrina; Mandzimba-Maloko, Bertina; Erfinanda, Lasti; Perret, Paul L.; Michalick, Laura; Smeele, Patrick J.; Lim, Endry H. T.; van den Brom, Charissa E.; Vonk, Alexander B. A.; Kaiser, Toralf; Suttorp, Norbert; Hippenstiel, Stefan; Sander, Leif E.; Kurth, Florian; Rauch, Ursula; Landmesser, Ulf; Haghikia, Arash; Preissner, Robert; Bogaard, Harm J.; Witzenrath, Martin; Kuebler, Wolfgang M.; Szulcek, Robert; Simmons, Szandor 分享 收藏 MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal PneumoniaMicroRNA-223抑制肺炎球菌肺炎期间的肺部炎症Goekeri, Cengiz; Pennitz, Peter; Groenewald, Wibke; Behrendt, Ulrike; Kirsten, Holger M.; Zobel, Christian; Berger, Sarah A.; Heinz, Gitta; Mashreghi, Mir-Farzin; Wienhold, Sandra-Maria; Dietert, Kristina; Dorhoi, Anca D.; Gruber, Achim; Scholz, Markus; Rohde, Gernot; Suttorp, Norbert; CAPNETZ Study Grp, Geraldine; Witzenrath, Martin; Nouailles, Geraldine 分享 收藏 Cenicriviroc for the treatment of COVID-19: first interim results of a randomised, placebo-controlled, investigator-initiated, double-blind phase II trialCenicriviroc治疗新型冠状病毒肺炎: 一项随机，安慰剂对照，研究者发起的双盲II期试验的第一个中期结果Kurth, Florian; Helbig, Elisa T.; Lippert, Lena J.; Thibeault, Charlotte; Barbone, Gianluca; Eckart, Marius A.; Kluge, Martin; Puengel, Tobias; Demir, Muenevver; Roehle, Robert; Keller, Theresa; Ruwwe-Gloesenkamp, Christoph; Witzenrath, Martin; Suttorp, Norbert; von Kalle, Christof; Sander, Leif E.; Jochum, Christoph; Tacke, Frank 分享 收藏 Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation内皮CFTR的丧失驱动肺部感染中的屏障衰竭和水肿形成，并且可以通过CFTR增强作用来靶向Erfinanda, Lasti; Zou, Lin; Gutbier, Birgitt; Kneller, Laura; Weidenfeld, Sarah; Michalick, Laura; Lei, Disi; Reppe, Katrin; Alves, Luiz Gustavo Teixeira; Schneider, Bill; Zhang, Qi; Li, Caihong; Fatykhova, Diana; Schneider, Paul; Liedtke, Wolfgang; Sohara, Eisei; Mitchell, Timothy J.; Gruber, Achim D.; Hocke, Andreas; Hippenstiel, Stefan; Suttorp, Norbert; Olschewski, Andrea; Mall, Marcus A.; Witzenrath, Martin; Kuebler, Wolfgang M. 分享 收藏 Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virus原代人肺细胞与肺组织样本和人A549肺细胞系的转录组比较突出了甲型流感病毒感染期间的细胞类型特异性反应Bertrams, Wilhelm; Hoenzke, Katja; Obermayer, Benedikt; Toennies, Mario; Bauer, Torsten T. T.; Schneider, Paul; Neudecker, Jens; Rueckert, Jens C.; Stiewe, Thorsten; Nist, Andrea; Eggeling, Stephan; Suttorp, Norbert; Wolff, Thorsten; Hippenstiel, Stefan; Schmeck, Bernd; Hocke, Andreas C. 分享 收藏 Functional limitations 12 months after SARS-CoV-2 infection correlate with initial disease severity: An observational study of cardiopulmonary exercise capacity testing in COVID-19 convalescentsSARS-CoV-2感染后12个月的功能限制与初始疾病严重程度相关: 新型冠状病毒肺炎康复期心肺运动能力测试的观察性研究Steinbeis, Fridolin; Knape, Philipp; Mittermaier, Mirja; Helbig, Elisa Theresa; Tober-Lau, Pinkus; Thibeault, Charlotte; Lippert, Lena Johanna; Xiang, Weiwei; Mueller-Plathe, Moritz; Steinbrecher, Sarah; Meyer, Hans-Jakob; Ring, Raphaela Maria; Ruwwe-Gloesenkamp, Christoph; Alius, Florian; Li, Yaosi; Mueller-Redetzky, Holger; Uhrig, Alexander; Lingscheid, Tilman; Grund, Daniel; Temmesfeld-Wollbrueck, Bettina; Suttorp, Norbert; Sander, Leif Erik; Kurth, Florian; Witzenrath, Martin; Zoller, Thomas 分享 收藏 Human alveolar progenitors generate dual lineage bronchioalveolar organoids人肺泡祖细胞产生双谱系支气管肺泡类器官Hoffmann, Karen; Obermayer, Benedikt; Hoenzke, Katja; Fatykhova, Diana; Demir, Zeynep; Loewa, Anna; Alves, Luiz Gustavo Teixeira; Wyler, Emanuel; Lopez-Rodriguez, Elena; Mieth, Maren; Baumgardt, Morris; Hoope, Judith; Firsching, Theresa C.; Toennies, Mario; Bauer, Torsten T.; Eggeling, Stephan; Tran, Hong-Linh; Schneider, Paul; Neudecker, Jens; Rueckert, Jens C.; Gruber, Achim D.; Ochs, Matthias; Landthaler, Markus; Beule, Dieter; Suttorp, Norbert; Hippenstiel, Stefan; Hocke, Andreas C.; Kessler, Mirjana 分享 收藏 A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics执行和分析跨物种单肺细胞转录组学的肺科医师指南Pennitz, Peter; Kirsten, Holger; Friedrich, Vincent D.; Wyler, Emanuel; Goekeri, Cengiz; Obermayer, Benedikt; Heinz, Gitta A.; Mashreghi, Mir-Farzin; Buettner, Maren; Trimpert, Jakob; Landthaler, Markus; Suttorp, Norbert; Hocke, Andreas C.; Hippenstiel, Stefan; Toennies, Mario; Scholz, Markus; Kuebler, Wolfgang M.; Witzenrath, Martin; Hoenzke, Katja; Nouailles, Geraldine 分享 收藏 
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