Gary Thomas - Publications, H-index & Citations

Gary Thomas

university of pittsburgh

51H指数

105论文数

10.0K被引数

收录论文 58

发表时间

PACS1 syndrome mutation disrupts dynein-mediated cargo transport via HDAC6 and BICD2 PACS1综合征突变通过HDAC6和BICD2破坏了驱动蛋白介导的货物转运

Communications Biology

IF5.1

2026-03-27

OAAI

Yunhan Yang; Laurel Thomas; Kun Chen; Sabrina Villar-Pazos; Wendy D. Haffey; Andrew D’Agostino; Kayleigh Fanelli; You-Jin Choi; Vihaan Rathi; Maanas S. Matlapudi; Kenneth D. Greis; Gary Thomas

The R203W substitution drives PACS-1 syndrome by disrupting intramolecular regulation R203W替换通过破坏分子内调控驱动PACS-1综合征

FEBS Journal

IF4.2

2026-03-01

OAAI

Krzysiak, Troy C.; Byeon, In-ja L.; Ponticelli, Ryan; Lucas, Mary E.; Thompson, Lariah; Dehaven, Christopher; Thomas, Gary; Gronenborn, Angela M.

Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1-or HDAC6-targeting therapy

NATURE COMMUNICATIONS

IF15.7

2023-10-17

OAAI

Villar-Pazos, Sabrina; Thomas, Laurel; Yang, Yunhan; Chen, Kun; Lyles, Jenea B.; Deitch, Bradley J.; Ochaba, Joseph; Ling, Karen; Powers, Berit; Gingras, Sebastien; Kordasiewicz, Holly B.; Grubisha, Melanie J.; Huang, Yanhua H.; Thomas, Gary

Genome-wide kinase-MAM interactome screening reveals the role of CK2A1 in MAM Ca2+ dynamics linked to DEE66

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-07-31

OAAI

Truong Thi My Nhung; Nguyen Phuoc Long; Tran Diem Nghi; Suh, Yeongjun; Nguyen Hoang Anh; Jung, Cheol Woon; Hong Minh Triet; Jung, Minkyo; Woo, Youngsik; Yoo, Jinyeong; Noh, Sujin; Kim, Soo Jeong; Lee, Su Been; Park, Seongoh; Thomas, Gary; Simmen, Thomas; Mun, Jiyoung; Rhee, Hyun-Woo; Kwon, Sung Won; Park, Sang Ki

Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins Rab32使用其效应物reticulon 3L触发线粒体相关膜蛋白 (MAM) 的自噬降解

BIOLOGY DIRECT

IF4.9

2021-11-07

OAAI

Herrera-Cruz, Maria Sol; Yap, Megan C.; Tahbaz, Nasser; Phillips, Keelie; Thomas, Laurel; Thomas, Gary; Simmen, Thomas

A novel role for PACS-1 in suppression of oncogenic replication stress in cancer cells

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Mani, Chinnadurai; Tripathi, Kaushlendra; Clark, David W.; Thomas, Gary; Palle, Komaraiah

The multifunctional protein PACS-1 is required for HDAC2-and HDAC3-dependent chromatin maturation and genomic stability

ONCOGENE

IF7.3

2020-01-27

OAAI

Mani, Chinnadurai; Tripathi, Kaushlendra; Luan, Shan; Clark, David W.; Andrews, Joel F.; Vindigni, Alessandro; Thomas, Gary; Palle, Komaraiah

Chemical Strike against a Dominant-Inherited MUC1-Frameshifted Protein Associated with Progressive Kidney Disease

Trends in Molecular Medicine

IF13.8

2019-10-01

OAAI

Thomas, Gary; Horwich, Arthur

The Multifunctional Sorting Protein PACS-2 Controls Mitophagosome Formation in Human Vascular Smooth Muscle Cells through Mitochondria-ER Contact Sites

CELLS

IF5.2

2019-06-25

OAAI

Moulis, Manon; Grousset, Elisa; Faccini, Julien; Richetin, Kevin; Thomas, Gary; Vindis, Cecile

An Insulin-Responsive Sensor in the SIRT1 Disordered Region Binds DBC1 and PACS-2 to Control Enzyme Activity

MOLECULAR CELL

IF16.6

2018-12-01

OAAI

Krzysiak, Troy C.; Thomas, Laurel; Choi, You-Jin; Auclair, Sylvain; Qian, Yiqi; Luan, Shan; Krasnow, Stephanie M.; Thomas, Laura L.; Koharudin, Leonardus M. I.; Benos, Panayiotis V.; Marks, Daniel L.; Gronenborn, Angela M.; Thomas, Gary

A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis (vol 102, pg 995, 2018)

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2018-10-01

OAAI

Olson, Heather E.; Jean-Marcais, Nolwenn; Yang, Edward; Heron, Delphine; Tatton-Brown, Katrina; van der Zwaag, Paul A.; Bijlsma, Emilia K.; Krock, Bryan L.; Backer, E.; Kamsteeg, Erik-Jan; Sinnema, Margje; Reijnders, Margot R. F.; Bearden, David; Begtrup, Amber; Telegrafi, Aida; Lunsing, Roelineke J.; Burglen, Lydie; Lesca, Gaetan; Cho, Megan T.; Smith, Lacey A.; Sheidley, Beth R.; El Achkar, Christelle Moufawad; Pearl, Phillip L.; Poduri, Annapurna; Skraban, Cara M.; Tarpinian, Jennifer; Nesbitt, Addie I.; van de Putte, Dietje E. Fransen; Ruivenkamp, Claudia A. L.; Rump, Patrick; Chatron, Nicolas; Sabatier, Isabelle; De Bellescize, Julitta; Guibaud, Laurent; Sweetser, David A.; Waxler, Jessica L.; Wierenga, Klaas J.; Donadieu, Jean; Narayanan, Vinodh; Ramsey, Keri M.; Nava, Caroline; Riviere, Jean-Baptiste; Vitobello, Antonio; Mau-Them, Frerdric Tran; Philippe, Christophe; Bruel, Ange-Line; Duffourd, Yannis; Thomas, Laurel; Lelieveld, Stefan H.; Schuurs-Hoeijmakers, Janneke; Brunner, Han G.; Keren, Boris; Thevenon, Julien; Faivre, Laurence; Thomas, Gary; Thauvin-Robinet, Christel

PACS-2 functions in colorectal cancer

AGING-US

IF3.9

2018-06-22

OAAI

Kveiborg, Marie; Thomas, Gary

A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2018-05-01

OAAI

Olson, Heather E.; Jean-Marcais, Nolwenn; Yang, Edward; Heron, Delphine; Tatton-Brown, Katrina; van der Zwaag, Paul A.; Bijlsma, Emilia K.; Krock, Bryan L.; Backer, E.; Kamsteeg, Erik-Jan; Sinnema, Margje; Reijnders, Margot R. F.; Bearden, David; Begtrup, Amber; Telegrafi, Aida; Lunsing, Roelineke J.; Burglen, Lydie; Lesca, Gaetan; Cho, Megan T.; Smith, Lacey A.; Sheidley, Beth R.; El Achkar, Christelle Moufawad; Pearl, Phillip L.; Poduri, Annapurna; Skraban, Cara M.; Tarpinian, Jennifer; Nesbitt, Addie I.; van de Putte, Dietje E. Fransen; Ruivenkamp, Claudia A. L.; Rump, Patrick; Chatron, Nicolas; Sabatier, Isabelle; De Bellescize, Julitta; Guibaud, Laurent; Sweetser, David A.; Waxler, Jessica L.; Wierenga, Klaas J.; Donadieu, Jean; Narayanan, Vinodh; Ramsey, Keri M.; Nava, Caroline; Riviere, Jean-Baptiste; Vitobello, Antonio; Mau-Them, Frederic Tran; Philippe, Christophe; Bruel, Ange-Line; Duffourd, Yannis; Thomas, Laurel; Lelieveld, Stefan H.; Schuurs-Hoeijmakers, Janneke; Brunner, Han G.; Keren, Boris; Thevenon, Julien; Faivre, Laurence; Thomas, Gary; Thauvin-Robinet, Christel

Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease

JOURNAL OF CELL SCIENCE

IF3.6

2017-06-01

OAAI

Thomas, Gary; Aslan, Joseph E.; Thomas, Laurel; Shinde, Pushkar; Shinde, Ujwal; Simmen, Thomas

PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage

CELL DEATH AND DIFFERENTIATION

IF15.4

2016-03-04

OAAI

Barroso-Gonzalez, J.; Auclair, S.; Luan, S.; Thomas, L.; Atkins, K. M.; Aslan, J. E.; Thomas, L. L.; Zhao, J.; Zhao, Y.; Thomas, G.

The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17

NATURE COMMUNICATIONS

IF15.7

2015-06-25

OAAI

Dombernowsky, Sarah Louise; Samsoe-Petersen, Jacob; Petersen, Camilla Hansson; Instrell, Rachael; Hedegaard, Anne-Mette Bornhardt; Thomas, Laurel; Atkins, Katelyn Mae; Auclair, Sylvain; Albrechtsen, Reidar; Mygind, Kasper Johansen; Frohlich, Camilla; Howell, Michael; Parker, Peter; Thomas, Gary; Kveiborg, Marie

A homeostatic switch in PACS-2 links membrane traffic to TRAIL-induced apoptosis

CELL CYCLE

IF3.4

2014-10-28

OAAI

You, Huihong; Thomas, Gary

The Multifunctional Sorting Protein PACS-2 Regulates SIRT1-Mediated Deacetylation of p53 to Modulate p21-Dependent Cell-Cycle Arrest

CELL REPORTS

IF6.9

2014-09-01

OAAI

Atkins, Katelyn M.; Thomas, Laura L.; Barroso-Gonzalez, Jonathan; Thomas, Laurel; Auclair, Sylvain; Yin, Jun; Kang, Hyeog; Chung, Jay H.; Dikeakos, Jimmy D.; Thomas, Gary

The Mechanism by Which a Propeptide-encoded pH Sensor Regulates Spatiotemporal Activation of Furin

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-06-01

OAAI

Williamson, Danielle M.; Elferich, Johannes; Ramakrishnan, Parvathy; Thomas, Gary; Shinde, Ujwal

The membrane traffic regulator PACS-1 mediates genome stability at S-phase of the cell cycle.

CANCER RESEARCH

IF16.6

2013-04-01

PREAI

Veena, Mysore S.; Basak, Saroj K.; Venkatesan, Natarajan; Zinabadi, Alborz; Thomas, Laurel; Thomas, Gary; Srivatsan, Eri S.

研究方向