Caroline S. Hill - Publications, H-index & Citations

Caroline S. Hill

Francis Crick Institute

61H指数

178论文数

1.9W被引数

收录论文 74

发表时间

Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling TGF-β与betaglycan及信号受体的结构揭示了复合物组装和信号传导的机制

NATURE COMMUNICATIONS

IF15.7

2025-02-26

OAAI

Wieteska, Lukasz; Taylor, Alexander B.; Punch, Emma; Coleman, Jonathan A.; Conway, Isabella O.; Lin, Yeu-Farn; Byeon, Chang-Hyeock; Hinck, Cynthia S.; Krzysiak, Troy; Ishima, Rieko; Lopez-Casillas, Fernando; Cherepanov, Peter; Bernard, Daniel J.; Hill, Caroline S.

Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is independent of NODAL signaling 在人类植入前发育中，多能原肠外胚层的启动和维持与NODAL信号通路无关。

DEVELOPMENTAL CELL

IF8.7

2025-01-01

OAAI

Brumm, A. Sophie; Mccarthy, Afshan; Gerri, Claudia; Fallesen, Todd; Woods, Laura; Mcmahon, Riley; Papathanasiou, Athanasios; Elder, Kay; Snell, Phil; Christie, Leila; Garcia, Patricia; Shaikly, Valerie; Taranissi, Mohamed; Serhal, Paul; Odia, Rabi A.; Vasilic, Mina; Osnato, Anna; Rugg-Gunn, Peter J.; Vallier, Ludovic; Hill, Caroline S.; Niakan, Kathy K.

Unlocking Enhanced Immunity in Pancreatic Ductal Adenocarcinoma: Activins Interplay with CAF-Stroma Mechanisms

BRITISH JOURNAL OF SURGERY

IF8.7

2024-03-18

PREAI

Mccluney, Simon; Park, Danielle; Miller, Daniel; Bloxham, Robert; Mehic, Merima; de Vries, Emma; Wang, Xuelu; Wilkinson, Robert; Hunt, James; Hyvonen, Marko; Boeing, Stefan; Sarker, Debashis; Hill, Caroline

An improved Erk biosensor detects oscillatory Erk dynamics driven by mitotic erasure during early development 改进的Erk生物传感器在早期开发过程中检测由有丝分裂擦除驱动的振荡Erk动力学

DEVELOPMENTAL CELL

IF8.7

2023-12-01

OAAI

Wilcockson, Scott G.; Guglielmi, Luca; Rodriguez, Pablo Araguas; Amoyel, Marc; Hill, Caroline S.

Context-dependent TGFβ family signalling in cell fate regulation

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2023-08-18

PREAI

Richardson, Louise; Wilcockson, Scott G.; Guglielmi, Luca; Hill, Caroline S.

Transforming growth factor β-independent shuttling of Smad4 between the cytoplasm and nucleus

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

279

OAAI

Pierreux, CE; Nicolás, FJ; Hill, CS

Arkadia activates Smad3/Smad4-Dependent transcription by triggering signal-induced SnoN degradation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

164

OAAI

Levy, Laurence; Howell, Michael; Das, Debipriya; Harkin, Sean; Episkopou, Vasso; Hill, Caroline S.

Kinetic analysis of smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor β-dependent nuclear accumulation of Smads

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

206

OAAI

Schmierer, B; Hill, CS

Smad4 dependency defines two classes of transforming growth factor β (TGF-β) target genes and distinguishes TGF-β-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

356

OAAI

Levy, L; Hill, CS

Transforming Growth Factor β-Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

283

OAAI

Daly, Amanda C.; Randall, Rebecca A.; Hill, Caroline S.

Recognition of phosphorylated-Smad2-containing complexes by a novel Smad interaction motif

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Randall, RA; Howell, M; Page, CS; Daly, A; Bates, PA; Hill, CS

Transforming Growth Factor β Inhibits Bone Morphogenetic Protein-Induced Transcription through Novel Phosphorylated Smad1/5-Smad3 Complexes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Groenroos, Eva; Kingston, Isabel J.; Ramachandran, Anassuya; Randall, Rebecca A.; Vizan, Pedro; Hill, Caroline S.

Nodal signaling establishes a competency window for stochastic cell fate switching

DEVELOPMENTAL CELL

IF8.7

2022-12-01

OAAI

Economou, Andrew D.; Guglielmi, Luca; East, Philip; Hill, Caroline S.

Mechanistic Insights into Deregulated TGF-β Family Signalling in Human Disease

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Hill, Caroline S.; Gori, Ilaria; Kjaer, Svend; George, Roger; Ramachandran, Anassuya; Mehic, Merima; Tolar, Pavel; Hyvonen, Marko; Jones, Chris

A network of transcription factors governs the dynamics of NODAL/Activin transcriptional responses

JOURNAL OF CELL SCIENCE

IF3.6

2022-04-26

OAAI

Coda, Davide M.; Patel, Harshil; Gori, Ilaria; Gaarenstroom, Tessa E.; Song, Ok-Ryul; Howell, Michael; Hill, Caroline S.

Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways

NATURE COMMUNICATIONS

IF15.7

2021-11-04

OAAI

Guglielmi, Luca; Heliot, Claire; Kumar, Sunil; Alexandrov, Yuriy; Gori, Ilaria; Papaleonidopoulou, Foteini; Barrington, Christopher; East, Philip; Economou, Andrew D.; French, Paul M. W.; McGinty, James; Hill, Caroline S.

Pathogenic ACVR1R206H activation by Activin A-induced receptor clustering and autophosphorylation

EMBO JOURNAL

IF8.3

2021-05-18

OAAI

Ramachandran, Anassuya; Mehic, Merima; Wasim, Laabiah; Malinova, Dessislava; Gori, Ilaria; Blaszczyk, Beata K.; Carvalho, Diana M.; Shore, Eileen M.; Jones, Chris; Hyvonen, Marko; Tolar, Pavel; Hill, Caroline S.

Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization

ELIFE

IF0

2021-01-08

OAAI

Gori, Ilaria; George, Roger; Purkiss, Andrew G.; Strohbuecker, Stephanie; Randall, Rebecca A.; Ogrodowicz, Roksana; Carmignac, Virginie; Faivre, Laurence; Joshi, Dhira; Kjaer, Svend; Hill, Caroline S.

Id1 and Id3 Are Regulated Through Matrix-Assisted Autocrine BMP Signaling and Represent Therapeutic Targets in Melanoma

ADVANCED THERAPEUTICS

IF2.6

2020-10-12

OAAI

Sedlmeier, Georg; Al-Rawi, Vanessa; Buchert, Justyna; Yserentant, Klaus; Rothley, Melanie; Steshina, Anastasia; Graessle, Simone; Wu, Ruo-Lin; Hurrle, Thomas; Richer, Wilfrid; Decraene, Charles; Thiele, Wilko; Utikal, Jochen; Abuillan, Wasim; Tanaka, Motomu; Herten, Dirk-Peter; Hill, Caroline S.; Garvalov, Boyan K.; Jung, Nicole; Braese, Stefan; Sleeman, Jonathan P.

Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses

CELL DEATH & DISEASE

IF9.6

2020-01-22

OAAI

Hutchinson, Luke D.; Darling, Nicola J.; Nicolaou, Stephanos; Gori, Ilaria; Squair, Daniel R.; Cohen, Philip; Hill, Caroline S.; Sapkota, Gopal P.

研究方向