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Apoorva Baluapuri

university of wurzburg
H指数:22
被引数:2,085

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GPCR antagonism via rewiring of receptor trafficking and degradation

通过重编程受体转运和降解实现GPCR拮抗

Nature
IF48.5
2026-09-300
OA
Kaitlin Rhee; Lawrence Shue; Akimasa Adachi; Pengwei Sun; James Osei-Owusu; Dingjingyu Zhou; Aoxing Cheng; Yi Ran Xu; Qingyue Li; Apoorva Baluapuri; Edward P. Harvey; Karen Adelman; Meredith A. Skiba; Bianxiao Cui; Jun R. Huh; Andrew C. Kruse; Xin Zhou
MYC multimers shield stalled replication forks from RNA polymerase
Nature
IF48.5
2022-11-230
PRE
Daniel Solvie; Apoorva Baluapuri; Leonie Uhl; Daniel Fleischhauer; Theresa Endres; Dimitrios Papadopoulos; Amel Aziba; Abdallah Gaballa; Ivan Mikicic; Ekaterina Isaakova; Celeste Giansanti; Jennifer Jansen; Marvin Jungblut; Teresa Klein; Christina Schülein-Völk; Hans Maric; Sören Doose; Markus Sauer; Petra Beli; Andreas Rosenwald; Matthias Dobbelstein; Elmar Wolf; Martin Eilers
RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells

RNA聚合酶I抑制诱导结直肠癌细胞的终末分化，生长停滞和对senolytics的脆弱性

MOLECULAR ONCOLOGY
IF4.5
2022-07-011
OA
Otto, Christoph; Kastner, Carolin; Schmidt, Stefanie; Uttinger, Konstantin; Baluapuri, Apoorva; Denk, Sarah; Rosenfeldt, Mathias T.; Rosenwald, Andreas; Roehrig, Florian; Ade, Carsten P.; Schuelein-Voelk, Christina; Diefenbacher, Markus E.; Germer, Christoph-Thomas; Wolf, Elmar; Eilers, Martin; Wiegering, Armin
NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-02-2318
OAAI
Doffo, Josefina; Bamopoulos, Stefanos A.; Koese, Hazal; Orben, Felix; Zang, Chuanbing; Pons, Miriam; den Dekker, Alexander T.; Brouwer, Rutger W. W.; Baluapuri, Apoorva; Habringer, Stefan; Reichert, Maximillian; Illendula, Anuradha; Kraemer, Oliver H.; Schick, Markus; Wolf, Elmar; van IJcken, Wilfred F. J.; Esposito, Irene; Keller, Ulrich; Schneider, Guenter; Wirth, Matthias
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma
NATURE COMMUNICATIONS
IF15.7
2022-01-1218
OAAI
Schick, Markus; Zhang, Le; Maurer, Sabine; Maurer, Hans Carlo; Isaakaidis, Konstandina; Schneider, Lara; Patra, Upayan; Schunck, Kathrin; Rohleder, Elena; Hofstetter, Julia; Baluapuri, Apoorva; Scherger, Anna Katharina; Slotta-Huspenina, Julia; Hettler, Franziska; Weber, Julia; Engleitner, Thomas; Maresch, Roman; Slawska, Jolanta; Lewis, Richard; Istvanffy, Rouzanna; Habringer, Stefan; Steiger, Katja; Baiker, Armin; Oostendorp, Robert A. J.; Miething, Cornelius; Lenhof, Hans-Peter; Bassermann, Florian; Chapuy, Bjoern; Wirth, Matthias; Wolf, Elmar; Rad, Roland; Mueller, Stefan; Keller, Ulrich
MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts

MYCN将核外泌体复合物招募到RNA聚合酶II以防止转录复制冲突

MOLECULAR CELL
IF16.6
2022-01-0122
OAAI
Papadopoulos, Dimitrios; Solvie, Daniel; Baluapuri, Apoorva; Endres, Theresa; Ha, Stefanie Anh; Herold, Steffi; Kalb, Jacqueline; Giansanti, Celeste; Schuelein-Voelk, Christina; Ade, Carsten Patrick; Schneider, Cornelius; Gaballa, Abdallah; Vos, Seychelle; Fischer, Utz; Dobbelstein, Matthias; Wolf, Elmar; Eilers, Martin
MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma

双链RNA的MYC和MIZ1-Dependent囊泡运输控制胰腺导管腺癌的免疫逃避

CANCER RESEARCH
IF16.6
2021-06-1819
OA
Krenz, Bastian; Gebhardt-Wolf, Anneli; Ade, Carsten P.; Gaballa, Abdallah; Roehrig, Florian; Vendelova, Emilia; Baluapuri, Apoorva; Eilers, Ursula; Gallant, Peter; D'Artista, Luana; Wiegering, Armin; Gasteiger, Georg; Rosenfeldt, Mathias T.; Bauer, Stefan; Zender, Lars; Wolf, Elmar; Eilers, Martin
Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription (vol 77, 1322.e1, 2020)
MOLECULAR CELL
IF16.6
2021-06-014
OAAI
Cossa, Giacomo; Roeschert, Isabelle; Prinz, Florian; Baluapuri, Apoorva; Vidal, Raphael Silveira; Schulein-Volk, Christina; Chang, Yun-Chien; Ade, Carsten Patrick; Mastrobuoni, Guido; Girard, Cyrille; Kumar, Amit; Wortmann, Lars; Walz, Susanne; Luhrmann, Reinhard; Kempa, Stefan; Kuster, Bernhard; Wolf, Elmar; Mumberg, Dominik; Eilers, Martin
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters

MYC的泛素化将转录延长与活性启动子上的双链断裂修复耦合在一起

MOLECULAR CELL
IF16.6
2021-02-0126
OA
Endres, Theresa; Solvie, Daniel; Heidelberger, Jan B.; Andrioletti, Valentina; Baluapuri, Apoorva; Ade, Carsten P.; Muhar, Matthias; Eilers, Ursula; Vos, Seychelle M.; Cramer, Patrick; Zuber, Johannes; Beli, Petra; Popov, Nikita; Wolf, Elmar; Gallant, Peter; Eilers, Martin
The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression (vol 39, pg 6841, 2020)
ONCOGENE
IF7.3
2020-12-010
OAAI
Jessen, Christina; Kress, Julia K. C.; Baluapuri, Apoorva; Hufnagel, Anita; Schmitz, Werner; Kneitz, Susanne; Roth, Sabine; Marquardt, Andre; Appenzeller, Silke; Ade, Carsten P.; Glutsch, Valerie; Wobser, Marion; Friedmann-Angeli, Jose Pedro; Mosteo, Laura; Goding, Colin R.; Schilling, Bastian; Geissinger, Eva; Wolf, Elmar; Meierjohann, Svenja
PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase
NATURE CHEMICAL BIOLOGY
IF13.7
2020-09-2893
OAAI
Adhikari, Bikash; Bozilovic, Jelena; Diebold, Mathias; Schwarz, Jessica Denise; Hofstetter, Julia; Schroeder, Martin; Wanior, Marek; Narain, Ashwin; Vogt, Markus; Dudvarski Stankovic, Nevenka; Baluapuri, Apoorva; Schoenemann, Lars; Eing, Lorenz; Bhandare, Pranjali; Kuster, Bernhard; Schlosser, Andreas; Heinzlmeir, Stephanie; Sotriffer, Christoph; Knapp, Stefan; Wolf, Elmar
The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
ONCOGENE
IF7.3
2020-09-2560
OAAI
Jessen, Christina; Kress, Julia K. C.; Baluapuri, Apoorva; Hufnagel, Anita; Schmitz, Werner; Kneitz, Susanne; Roth, Sabine; Marquardt, Andre; Appenzeller, Silke; Ade, Carsten P.; Glutsch, Valerie; Wobser, Marion; Friedmann-Angeli, Jose Pedro; Mosteo, Laura; Goding, Colin R.; Schilling, Bastian; Geissinger, Eva; Wolf, Elmar; Meierjohann, Svenja
Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription

NUAK1对蛋白磷酸酶1的局部抑制可促进剪接体活性并揭示MYC敏感的转录反馈控制

MOLECULAR CELL
IF16.6
2020-03-0137
OAAI
Cossa, Giacomo; Roeschert, Isabelle; Prinz, Florian; Baluapuri, Apoorva; Vidal, Raphael Silveira; Schuelein-Voelk, Christina; Chang, Yun-Chien; Ade, Carsten Patrick; Mastrobuoni, Guido; Girard, Cyrille; Wortmann, Lars; Walz, Susanne; Luehrmann, Reinhard; Kempa, Stefan; Kuster, Bernhard; Wolf, Elmar; Mumberg, Dominik; Eilers, Martin
A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer

MYC-GCN2-eIF2α 负反馈环限制蛋白质合成以防止结直肠癌中MYC依赖性细胞凋亡

NATURE CELL BIOLOGY
IF19.1
2019-11-0476
OAAI
Schmidt, Stefanie; Gay, David; Uthe, Friedrich Wilhelm; Denk, Sarah; Paauwe, Madelon; Matthes, Niels; Diefenbacher, Markus Elmar; Bryson, Sheila; Warrander, Fiona Clare; Erhard, Florian; Ade, Carsten Patrick; Baluapuri, Apoorva; Walz, Susanne; Jackstadt, Rene; Ford, Catriona; Vlachogiannis, Georgios; Valeri, Nicola; Otto, Christoph; Schuelein-Voelk, Christina; Maurus, Katja; Schmitz, Werner; Knight, John Raymond Philip; Wolf, Elmar; Strathdee, Douglas; Schulze, Almut; Germer, Christoph-Thomas; Rosenwald, Andreas; Sansom, Owen James; Eilers, Martin; Wiegering, Armin

研究方向

暂未获取到该数据
E
Elmar Wolf
H 指数:47论文数:173被引数:6,267
M
Martin Eilers
H 指数:89论文数:386被引数:2.8万
C
Carsten P. Ade
H 指数:20论文数:89被引数:1,683
S
Susanne Walz
H 指数:24论文数:80被引数:3,796
J
Julia Hofstetter
H 指数:7论文数:12被引数:512
P
Peter Gallant
H 指数:32论文数:126被引数:4,473
C
Christina Schülein‐Völk
H 指数:12论文数:53被引数:951
A
Armin Wiegering
H 指数:35论文数:315被引数:4,637
P
Pranjali Bhandare
H 指数:8论文数:23被引数:465
D
Daniel Solvie
H 指数:7论文数:17被引数:365