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E

Elmar Wolf

university of wurzburg
H指数:47
被引数:6,268

个人简介

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工作经历

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荣誉奖项

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Targeted degradation of USP7 in solid cancer cells reveals distinct effects of deubiquitinase degraders and inhibitors

靶向降解实体癌细胞中的USP7揭示了去泛素化酶降解剂和抑制剂的特定效应

Nature Communications
IF15.7
2026-05-130
OAAI
Nikolas Klink; Sebastian Urban; Johanna A. Seier; Bikash Adhikari; Martin P. Schwalm; Juliane Müller; Madeleine Dorsch; Philine Steinbach; Jennifer Jung; Markus Vogt; Farnusch Kaschani; Johannes Koch; Siska Führer; Markus Kaiser; Nina Schulze; Stefan Knapp; Elmar Wolf; Annette Paschen; Barbara M. Grüner; Malte Gersch
Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma

基于靶向和表观遗传的联合治疗通过稳定胰腺导管腺癌GATA6-dependent MHCI表达来增强抗肿瘤免疫力

Nature Communications
IF15.7
2026-02-060
OAAI
JuanFei Peng; JiaJin Yang; Georgia Antonopoulou; Rui Fang; Bikash Adhikari; Markus Vogt; Elmar Wolf; Chong Sun; Shangce Du; Laura Godfrey; Aayush Gupta; Marija Trajkovic-Arsic; Nicole Teichmann; Barbara T. Grünwald; Niklas Krebs; Katja Steiger; Carolin Mogler; Kristina Althoff; Xin Wang; Giovanni Giglio; Sven-Thorsten Liffers; Konstantinos Savvatakis; Rickmer Braren; Rita T. Lawlor; Aldo Scarpa; Diana Behrens; Karl S. Lang; Phyllis F. Cheung; Jens T. Siveke
Unhooking the Hook: Optimization of the Aurora A Targeting PROTAC JB170 to CCT400028, an In Vitro Degrader Chemical Probe
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2026-01-010
PRE
O'Hanlon, Jack A.; Gutsche, Katrin; Muller, Juliane Elisabeth; Ranjan Prusty, Nihar; Mirza, Amin; Roumeliotis, Theodoros I.; Yang, Hengzhang; Stubbs, Mark; Hallett, Stephen T.; Eing, Lorenz; Mcandrew, Peter Craig; Choudhary, Jyoti Sharma; Le Bihan, Yann-Vai; Caldwell, John; Van Montfort, Rob L. M.; Workman, Paul; Wolf, Elmar; Newton, Gary K.; Evans, Lindsay E.
Workflow for E3 Ligase Ligand Validation for PROTAC Development
ACS CHEMICAL BIOLOGY
IF3.8
2025-02-110
OAAI
Miletic, Nebojsa; Weckesser, Janik; Mosler, Thorsten; Rathore, Rajeshwari; Hoffmann, Marina E.; Gehrtz, Paul; Schlesiger, Sarah; Hartung, Ingo V.; Berner, Nicola; Wilhelm, Stephanie; Mueller, Juliane; Adhikari, Bikash; Nemec, Vaclav; Sivashanmugam, Saran Aswathaman; Elson, Lewis; Holzmann, Hanna; Schwalm, Martin P.; Hoffmann, Lasse; Azeez, Kamal Rayees Abdul; Mueller, Susanne; Kuster, Bernhard; Wolf, Elmar; Dikic, Ivan; Knapp, Stefan
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer
ONCOGENE
IF7.3
2024-10-230
OAAI
Reissland, Michaela; Hartmann, Oliver; Tauch, Saskia; Bugter, Jeroen M.; Prieto-Garcia, Cristian; Schulte, Clemens; Loebbert, Sinah; Solvie, Daniel; Bitman-Lotan, Eliya; Narain, Ashwin; Jacomin, Anne-Claire; Schuelein-Voelk, Christina; Fuss, Carmina T.; Pahor, Nikolett; Ade, Carsten; Buck, Viktoria; Potente, Michael; Li, Vivian; Beliu, Gerti; Wiegering, Armin; Grossmann, Tom; Eilers, Martin; Wolf, Elmar; Maric, Hans; Rosenfeldt, Mathias; Maurice, Madelon M.; Dikic, Ivan; Gallant, Peter; Orian, Amir; Diefenbacher, Markus E.
CHIMERIC AURORA A KINASE (AURKA) DEGRADERS EFFICIENTLY TARGET N-MYC
NEURO-ONCOLOGY
IF13.4
2023-06-120
OAAI
Valinciute, Gintvile; Eing, Lorenz; Mihalic, Jeffrey; Casey, Colleen E.; Tian, Hua; Adhikari, Bikash; Guiducci, Cristiana; Rountree, Ryan; Grohmann, Christoph; Sridharan, Sangita; Lu, Ya-Wen; Vezina-Dawod, Simon; Wegrzyniak, Eric; Chaterjee, Abhinav; Hansen, Gwenn M.; Maris, John M.; Mosse, Yael P.; Eilers, Martin; Wolf, Elmar; Roussel, Martine F.

研究方向

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M
Martin Eilers
H 指数:89论文数:386被引数:2.8万
A
Apoorva Baluapuri
H 指数:22论文数:58被引数:2,086
C
Carsten P. Ade
H 指数:20论文数:89被引数:1,683
B
Bikash Adhikari
H 指数:11论文数:34被引数:1,124
S
Susanne Walz
H 指数:24论文数:80被引数:3,796
B
Björn von Eyß
H 指数:21论文数:55被引数:2,629
R
Reinhard Lührmann
H 指数:100论文数:358被引数:3.5万
P
Peter Gallant
H 指数:32论文数:126被引数:4,473
J
Julia Hofstetter
H 指数:7论文数:12被引数:513
C
Christina Schülein‐Völk
H 指数:12论文数:53被引数:951